Abstract: A laser treatment apparatus for irradiating a treatment part with a laser beam for treatment is disclosed. The apparatus includes a treatment light irradiation unit including a treatment light source which emits the treatment laser beam, an irradiation optical system which delivers the treatment laser beam emitted from the light source to irradiate the treatment part, and a laser emission end unit internally provided with a part of the irradiation optical system. The apparatus further includes a movement unit which moves the emission end unit with respect to the treatment part, a determination unit which determines an irradiation position of the treatment laser beam, and a control section which transmits a control signal to the movement unit based on a determination result by the determination unit and controls laser irradiation.

Abstract: A method for photoselective vaporization of uterine tissue includes delivering laser radiation to the treatment area on the tissue, via an optical fiber for example, wherein the laser radiation has a wavelength and irradiance in the treatment area on the surface of the tissue sufficient because vaporization of a substantially greater volume of tissue than a volume of residual coagulated tissue caused by the laser radiation. The laser radiation is generated using a neodymium doped solid-state laser, including optics producing a second or higher harmonic output with greater than 60 watts average output power. The delivered laser radiation has a wavelength for example in a range of about 200 run to about 650 nm, and has an average irradiance in the treatment area greater than about 10 kilowatts/cm2, in a spot size of at least 0.05 mm2.

Abstract: Pain localized to a particular body area is treated by subjecting the affected body area to a flexible array of light emitting units that conforms to the contour of the affected body area, thereby delivering a therapeutic dose of light to that affected body area. A flexible array of light emitting units is conformingly placed onto the localized pain area. The light emitting units are energized to deliver a therapeutic dose of light over the localized pain area. Additionally, the same methodology is useful for treating facial wrinkles, remodeling facial and body collagen and providing holistic relaxation and stress relief.

Abstract: A method and apparatus are provided for targeting lipid-rich tissue to effect a desired, the method/apparatus involving irradiating the lipid-rich tissue with energy at a wavelength preferentially absorbed by lipid cells, such wavelength being preferably in a band between 880 nm and 935 nm, 1150 nm and 1230 nm, 1690 nm to 1780 nm, or 2250 nm to 2450 nm with a fluence and duration sufficient to achieve a desired treatment. For preferred embodiments, the irradiation wavelength is between 900-930 nm, 1190-1220 nm, 1700-1730 nm, or 2280-2350 nm. The method and apparatus may for example be used to target one or more sebaceous glands for the treatment of acne or hair removal, to target subcutaneous fat for removal thereof or for targeting fat on anatomical elements for various purposes.

Abstract: A long pulse alexandrite laser hair removal system is disclosed using light pulses of greater than 1 msec and fluences between 10 and 50 J/cm2. The use of an alexandrite laser allows good penetration while still achieving an acceptable combination of hemoglobin and melanin absorption. The use an index-matching application on the skin sections to be treated is also described. This substance will be absorbed into the epidermal layer to provide better coupling of the laser light into the skin. Also, and most advantageously, it will reduce reflections at the epidermal-dermal junction, which can lead to the damage of the skin. Also a topical thermal or photochromic indicator is suggested since skin irradiation in the near-infrared generally does not produce any characteristic skin color change as is found when using pulsed dye lasers, for example.

Abstract: A laser treatment device and process with controlled cooling. The device contains a cooling element with high heat conduction properties, which is transparent to the laser beam. A surface of the cooling element is held in contact with the tissue being treated while at least one other surface of the cooling element is cooled by the evaporation of a cryogenic fluid. The cooling is coordinated with the application of the laser beam so as to control the temperatures of all affected layers of tissues. In a preferred embodiment useful for removal of wrinkles and spider veins, the cooling element is a sapphire plate. A cryogenic spray cools the top surface of the plate and the bottom surface of the plate is in contact with the skin. In preferred embodiments the wavelength of the laser beam is chosen so that absorption in targeted tissue is low enough so that substantial absorption occurs throughout the targeted tissue. In a preferred embodiment for treating large spider veins with diameters in the range of 1.

Abstract: A method for the treatment of Barrett's Esophagus of a patient having endothelial esophageal complications. The treatment comprises connecting a wavelength specific light source to an elongated light guide having a distal end, the light guide arranged within a lumen of a steerable endoscope, guiding the endoscope into the esophagus of the patient, energyzing the light source, and manipulating the distal end of the light source onto a target on the endothelial complications inside of the patient's esophagus for the selective thermolysis of the target in the esophagus, thereby reverting the red secretory esophageal lining to a normal lining.

Abstract: A surgical apparatus has a body portion that includes a shaft terminating in a distal head or tip and a means for directing light radiation from the apparatus onto the lining of a body cavity for treating an ailment in a body cavity of a patient as for example a gastrointestinal ailment of a patient such as gastritis, gastric ulcer, duodenal ulcer, gastric cancer, gastric lymphoma, ulcerative colitis, or Crohn's disease as well as for treating diseases of the circulatory system, urogenital systems and other body cavities. The method of use of the apparatus comprises inserting the shaft of the apparatus into a body cavity, e.g., stomach or colon, of the patient to place the distal tip of the shaft in the desired position. The body cavity of the patient is then irradiated with light radiation so as to kill or debilitate microorganisms lining the body cavity without serious destruction of the body tissue of the patient to thereby improve or alleviate one or more of the symptoms of the ailment.

Abstract: A single laser system that operates at any one or any combination of at least five wavelengths each of which are important to medical facilities offering laser cosmetic services. The present invention includes appropriate laser optics and a crystal rod configured to produce a first pulsed laser beam, and appropriate laser optics and a second crystal rod configured to produce a second pulsed laser beam. Both rods are pumped simultaneously preferably from the same pump source. Beams from each of these lasers are frequency doubled using frequency-doubling crystals to produce third and fourth laser beams. The frequencies of the first and second beams are also combined in a sum frequency generating crystal to produce a fifth laser beam. In a preferred embodiment the first and second laser beams are produced using YAP:Nd crystals with wavelengths of 1079 nm and 1341 nm. The third and fourth laser beams at 539.5 nm and 670.

Abstract: A laser system in which the gain medium is an excited YAP:Nd crystal. The system is configured so that the crystal produces a twin laser beam comprising wavelengths at both 1079 nm and 1340 nm with substantial intensities at each wavelength. Optical components are described which establish the desired ratio of the intensities of the light at each of the two wavelengths. These ratios, I1079 nm/I1340 nm, may vary from about 0.1 to 10. In a preferred embodiment of the invention a kit including a YAP:Nd crystal and a specially coated output coupler is provided for converting an existing Nd:YAG laser system to a twin light laser capable of producing the above described twin laser beam.

Abstract: A method and apparatus are provided to increase the accuracy and safety of ablative laser treatments of the eye. In an illustrative embodiment, tissue is removed from the cornea, via a laser, to provide an effluent from the cornea. The effluent is aspirated and deposited into a chemical analyzer. The amount of effluent that has been deposited is quantitated. Data relating to a dimension of the ablated cornea is inputted to a computer and data relating to the quantitized effluent is also inputted to the computer. The computer uses the quantitized effluent data and the inputted dimension data to estimate the number of diopters of treatment accomplished. The estimated number of diopters of treatment accomplished is compared to a desired number of diopters of treatment and the laser treatment is modified based on the comparison for most accurate optical results.

Abstract: A long pulse alexandrite laser for treating dermatological specimens is disclosed. The use of alexandrite allows operation in the near-infrared, specifically in a 50 nm range surrounding 755. Infrared in this range allows good penetration while still achieving an acceptable ratio of hemoglobin to melanin absorption. In operation, the laser generates pulses having a durations between 5 and 100 msec and fluences between 10 and 50 J/cm2. A light delivery system is provided that transmits the laser light output pulse to dermatological targets of a patient. The invention is also directed to a hair removal system. Here, it is desirable to use an index-matching application on the skin sections to be treated, and a visual indicator is thermo- or photo-responsive or otherwise responsive to the laser light pulse to generate a visible change. Also, the invention is directed to a combined sclerotherapy and light treatment method and kit for unwanted veins.

Abstract: A light irradiation apparatus for a dental photo polymerization composite resin of multi-purpose type which can efficiently and completely polymerize and cure the dental photo polymerization composite resin using a combination of the camphor quinone and the tertiary amine as the photo polymerization catalyst, and can also polymerize and cure the dental photo polymerization composite resin using the acylphosphine oxide as the newly developed photo polymerization initiator, with a structure such that there are arranged a blue ray radiation LED 5 having luminous wavelengths peaked at a wavelength of 430 nm or more but not more than 500 nm, and a near ultraviolet rays and/or violet rays radiation LED 6 having luminous wavelengths peaked at a wavelength of 350 nm or more but less than 430 nm, and there is provided a circuit changing switch 7 at least for simultaneously turning on these two kinds of LEDs 5, 6 and for turning on only the near ultraviolet rays and/or violet rays radiation LED 6.

Abstract: A method and apparatus are provided for targeting lipid-rich tissue to effect a desired, the method/apparatus involving irradiating the lipid-rich tissue with energy at a wavelength preferentially absorbed by lipid cells, such wavelength being preferably in a band between 880 nm and 935 nm, 1150 nm and 1230 nm, 1690 nm to 1780 nm, or 2250 nm to 2450 nm with a fluence and duration sufficient to achieve a desired treatment. For preferred embodiments, the irradiation wavelength is between 900-930 nm, 1190-1220 nm, 1700-1730 nm, or 2280-2350 nm. The method and apparatus may for example be used to target one or more sebaceous glands for the treatment of acne or hair removal, to target subcutaneous fat for removal thereof or for targeting fat on anatomical elements for various purposes.

Abstract: Systems, methods and apparatus for generating images of portions of the patient's eye, such as the anterior surface of the cornea. The methods and apparatus of the present invention are particularly useful for directly imaging the profile of the ablated region of the cornea during or immediately following a laser ablation procedure, such as photorefractive keratometry (PRK), phototherapeutic keratectomy (PTK), laser in-situ keratomileusis (LASIK) or the like. These methods and apparatus allow the surgeon to precisely image the exterior edge of the eye to characterize the profile of ablated corneas and to determine the spatial variance of tissue ablation rates during the surgical procedures. Methods and apparatus are also provided for generating one or more images depicting the profile of the ablated region of the cornea. The profile is registered with a pre-ablation profile to provide feedback regarding the true ablation properties of the eye.

Abstract: A device is disclosed which is therapeutically beneficial to the well-being of living organisms such as humans, animals, and/or plant life, using photon or light waves. The device is intended to lie against the skin or surface, near the skin/surface, and/or from a distance ranging up to several feet from the skin/surface. The device is intended to be used for: general relaxation and detoxification of an organism; stimulating the healing process in an organism which is ill, diseased or injured; aiding in the elimination of pain and inflammation in an organism; stimulating/sedating the acupressure meridian system of an organism and rebalancing the electromagnetic energy-field surrounding the organism.

Abstract: A system and method is disclosed for improved treatment of oral tissues using 980 nm laser radiation and a handpiece with means for concurrently delivering the laser radiation and a liquid/gas spray onto the treatment area to improve the treatment effects. Unwanted heating and carbonization of surrounding tissues is reduced. The liquid/gas spray may be mixed inside the handpiece or in a separate device. The combination of cooling sprays with radiation wavelengths having high absorption in water has previously been avoided due to the thought that energy absorption by the cooling fluid would render the energy delivered to the tissue uncontrollable and of minimal benefit. Preferably, pulsed laser light provides a localized energy deposition and heating to avoid unwanted heating of underlying tissue. The liquid spray flushes way tissue debris in addition to cooling the treated tissue.

Abstract: A method is provided of removing hair from the skin of a patient using a laser apparatus capable of producing an emission of laser energy in the form of a group of pulses having defined parameters, being a defined pulse group, and using an optical delivery system, which includes the steps of controlling the laser apparatus in each emission of laser energy to emit a defined pulse group of 2 to 15 pulses of coherent light energy; transmitting the defined pulse group of pulses of coherent light energy through an optical delivery system to the same spot on the skin of the patient; irradiating the same spot on the skin containing the hair to be removed with the defined pulse group of coherent light energy transmitted through the optical delivery system from the laser apparatus; controlling the laser apparatus in each emission of laser energy to emit the defined pulse group through the optical delivery system, the defined pulse group having 2 to 15 pulses at a wavelength in the range of 550 to 1200 nm, each pulse a

Abstract: Method and apparatus to cause the cessation of hair growth on a specific area of the body and for the treatment of unwanted dermatological conditions. The area of treatment is exposed to a particular pattern and wavelength of light generated by multiple flashlamps, which allow simultaneous, overlap, or consecutive firing. Controlling the intensity of light, the output wavelength and the delay between pulses allow treatment to be adjusted to different skin conditions and hair types. Skin damage is virtually eliminated by the length and characteristic shape of the individual pulse of light.

Abstract: A method for photoselective vaporization of prostate tissue includes delivering laser radiation to the treatment area on the tissue, via an optical fiber for example, wherein the laser radiation has a wavelength and irradiance in the treatment area on the surface of the tissue sufficient because vaporization of a substantially greater volume of tissue than a volume of residual coagulated tissue caused by the laser radiation. The laser radiation is generated using a neodymium doped solid-state laser, including optics producing a second or higher harmonic output with greater than 60 watts average output power. The delivered laser radiation has a wavelength for example in a range of about 200 nm to about 650 nm, and has an average irradiance in the treatment area greater than about 10 kilowatts/cm2, in a spot size of at least 0.05 mm2.

Abstract: The present invention provides for a device, a method, and a treatment system for chronic disease conditions. The present invention was designed using the theoretical concepts of Quantum Biology. The principles of operation are based on the device's ability to stimulate a Bose-Einstein condensate and excitation of Frolich resonance in living tissue The wavenumbers necessary for this excitation are derived from the solution to the equations for optical phonon scattering in living tissue generated by optical photon excitation. The establishment of this degeneracy condition induces a super conducting state in the tissue. This super conducting state facilitates DNA replication, transcription and translation, thereby allowing the proper formation or regeneration of healthy tissue. This superconducting state provides the conditions necessary for establishing the violation of time reversal invariance in living tissue.

Abstract: A method for photoselective vaporization of prostate tissue includes delivering laser radiation to the treatment area on the tissue, via an optical fiber for example, wherein the laser radiation has a wavelength and irradiance in the treatment area on the surface of the tissue sufficient because vaporization of a substantially greater volume of tissue than a volume of residual coagulated tissue caused by the laser radiation. The laser radiation is generated using a neodymium doped solid-state laser, including optics producing a second or higher harmonic output with greater than 60 watts average output power. The delivered laser radiation has a wavelength for example in a range of about 200 nm to about 650 nm, and has an average irradiance in the treatment area greater than about 10 kilowatts/cm2, in a spot size of at least 0.05 mm2.

Abstract: A photocoagulation apparatus for coagulating an affected part of a patient by irradiating the part with a treatment laser beam emitted from a laser oscillator (10) is disclosed. The apparatus includes an input section (3) for setting an irradiation condition of the treatment laser beam, a detecting section (27, 40-43, 46, 47, 51) for optically detecting a coagulating state of a coagulation part produced by irradiation of the treatment beam, an analysis section (51) for analyzing the coagulating state detected by the detection section as compared with a desired coagulating state to be produced by irradiation of the treatment laser beam under the irradiation condition set with the input section, and a control section (50) for instructing a change in the irradiation condition as needed based on a result of analysis by the analysis section.

Abstract: The invention concerns a laser photocoagulator comprising a laser emitting at a wavelength within the ICG absorption spectrum and provided with focusing means and a programmed or controlled module powering the laser such that the mean fluence (F) at the focus starting from an initial time varies according to an increasing function in time not varying at any time by more than 10% of an increasing monoexponential corresponding to formula F−F0(1−e−t/r) wherein F is the initial fluence and &tgr; is a time constant ranging between 3 and 5 mn.

Abstract: A long pulsed dye laser device for selective photothermolysis comprises at least two pulsed dye lasers, such as flash lamp excited dye lasers, each generating corresponding pulsed laser beams successively in time. These laser can be coordinated by a synchronizer that sequentially triggers the lasers. A combining network merges the pulse laser beams into a combined beam and a delivery system conveys the combined pulse laser beam to a patient. An example of a delivery device is a single optical fiber. This invention enables production of the necessary pulse widths, on the order of 2 msec, which can not be achieved by individual dye lasers, generally lower than 0.8 msec. Also disclosed is a selective photothermolysis method. This method comprises irradiating a tissue section of a patient with a pulsed laser beam having a changing color across a time period of the pulse.

Abstract: An apparatus and technique for transscleral light-mediated biostimulation of the trabecular plates of a patient's eye in a treatment for glaucoma or ocular hypertension. The apparatus includes; (i) a working end geometry for contacting the anterior surface of the sclera and cornea to insure that a laser emission reaches the trabecular meshwork from a particular location on the anterior surface of the sclera, (ii) a laser energy source providing a wavelength appropriate for absorption beneath the anterior scleral surface to the depth of the trabecular plates, and (iii) a dosimetry control system for controlling the exposure of the laser emission at the particular spatial locations. The device uses a light energy source that emits wavelengths in the near-infrared portion of the spectrum, preferably in the range of about 1.30 &mgr;m to 1.40 &mgr;m or from about 1.55 &mgr;m to 1.85 &mgr;m.

Abstract: A apparatus and method for controlling an apparatus for removing tissue from the eye performs various types of corrections using a relatively large beam, but oscillating, or dithering, that being to prevent reinforcing ridges from being formed during the tissue removal process. Further, various types of correction, such as hyperopia and astigmatism correction, are performed using a large beam that is scanned over the area to be ablated using overlapping shots. Further, the epithelium in the area to be treated is removed using an infrared fluorescent dye to dye the epithelium, and then observing the fluorescent patterns from the epithelium area to be removed. Once a certain area is no longer fluorescent after laser shots, smaller shots are then applied, selectively removing the epithelium from the remaining regions. Again, the fluorescence patterns are observed, and the process is repeated until no epithelium remains.

Abstract: A selective aperture for a laser delivery system for providing incision, ablation and coagulation. A laser crystal disposed between two reflective surfaces forms a laser beam. An aperture member positioned between the laser crystal and one of the reflective surfaces includes a substantially circular aperture for passing the laser beam. The size of the aperture is selectively adjustable. The aperture member has a plurality of apertures of various different sizes and is rotatable about an axis of rotation. The axis of rotation is parallel to the longitudinal axis of the laser crystal. By appropriately rotating the aperture member, a selected one of the apertures is positioned to pass the laser beam. A stepper motor and flexible shaft are utilized for rotating the aperture member. At least one of the apertures is surrounded by a beveled portion of the rotatable member. Alternatively, two lasers with different size fixed apertures could be utilized and directed to a common surface.

Abstract: Surgical apparatus and surgical methods are proposed for the prevention of age-related macular degeneration (AMD) and choroidal neovascularization (CNV), and other eye diseases such as glaucoma by removal of the sclera tissue to reduce its rigidity and increase the flood flow and decrease pressure in the choriocapillaris. The disclosed preferred embodiments of the system consists of a tissue ablation means and a control means of ablation patterns and a fiber delivery unit. The basic laser beam includes UV lasers and infrared lasers having wavelength ranges of (0.15-0.36) microns and (0.5-3.2) microns and diode lasers of about 0.98, 1.5 and 1.9 microns.

Abstract: A laser system and process by which prior art medical and cosmetic laser techniques using laser beams chosen to produce selective thermolysis are enhanced by the addition of a second laser beam chosen for much deeper transmission in tissue and more uniform absorption. Preferred embodiments include enforcement with a 1079 nm YAP:Nd laser beam of a 532 nm beam produced by a frequency doubled YAG:Nd laser beam.

Abstract: The invention provides improved structures, systems, and methods for supporting the optical elements of a microscope relative to the optical train of a laser surgery system. As the field of view of the microscope is substantially fully determined by the position of the objective lens, the laser delivery optics and the microscope can be aligned with a target location of the patient's eye by accurately aligning just the objective lens with the delivery optics. By structurally separating the objective lens from the other optical components of the microscope, and by maintaining accurate alignment between the objective lens and the laser delivery optics with a simple, tight-tolerance support structure, the remaining optical components of the microscope can be allowed to “float” relative to the objective lens with a looser-tolerance without degrading the operator's ability to align, observe, and optically direct an ophthalmic laser procedure.

Abstract: A method for enhancing the accuracy of PRK wherein a UV power meter is placed in the optical path of the laser beam. In one preferred embodiment, the power meter is placed distal to the last optical element so that any optical degradation that affects laser performance is taken into account. The meter consists of a UV-B cube and a pulnix camera with a software package. The meter is used to monitor the fluence of each laser pulse. The power meter is used to size each pulse and to quantify the energy in each pulse. Sensing means is employed to measure intraoperative pulse-to-pulse energy during photorefractive keratectomy (PRK), using said data in conjunction with the location of the pulse within the ablation zone to determine the cumulative energy thus being achieved, and adjusting said laser to treat more or less at each point based upon the difference between the ideal cumulative energy map and the observed cumulative energy map derived from intraoperative power determination.

Abstract: Methods are provided for treating prostate glands or other targeted soft tissue using a solid-state laser. The laser can be operated to generate a pulsed output beam having pulse durations of between 0.1 and 500 milliseconds. The output beam is delivered to the targeted tissue through an optical fiber, preferably terminating in a side-firing probe or diffusing tip. By operating the laser in a long-duration pulse mode, charring of the targeted tissue is initiated quickly, thereby increasing ablation rates and reducing overall procedure time.

Abstract: A laser therapy assembly (1) for the revascularization of muscular tissues (t), especially cardiac muscular tissue, with a laser source (2) and an optical coupling unit (9, 11) for transmitting the laser beam (L) into the muscular tissue, with an ultrasound generator (6) connected to the optical coupling unit for a transfer of heat to the muscular tissue, which can be regulated independently from the laser beam with the purpose of producing a thermal effect that can be separately adjusted, especially a marginal thermal necrosis, in a channel generated in the muscular tissue.

Abstract: A photosensitizer together with complementary light energy are used to prevent the development of infection associated with an indwelling medical catheter or device. Light of a selected wavelength or wavelength band is coupled to the catheter or device and transmitted by a wall or walls thereof to one or both of the external and internal surfaces thereof. The catheter or device also incorporates at least one photosensitizer which releases a toxic substance when activated by the light energy which destroys bacteria on or around the catheter or device. A method of preventing infection using photosensitizers and complementary light energy is also disclosed.

Abstract: Laser energy produced by a laser operating In the mid-infrared region (approximately 2 micrometers) Is delivered by an optical fiber in a catheter to a surgical site for biological tissue removal and repair. Disclosed laser sources which have an output wavelength in this region include: Holmium-doped Yttrium Aluminum Garnet (Ho:YAG), Holmium-doped Yttrium Lithium Fluoride (Ho:YLF), Erbium-doped YAG, Erbium-doped YLF and Thulium-doped YAG. For tissue removal, the lasers are operated with relatively long pulses at energy levels of approximately 1 joule per pulse. For tissue repair, the lasers are operated in a continuous wave mode at low power. Laser output energy is applied to a silica-based optical fiber which has been specially purified to reduce the hydroxyl-ion concentration to a low level. The catheter may be comprised of a single optical fiber or a plurality of optical fibers arranged to give overlapping output patterns for large area coverage.

Abstract: The present invention is a method and apparatus for removing the lens of the eye in which pulsed ultrasound and laser energy are transmitted by means of an optical fiber delivery system to the lens of the eye for therapeutic purposes. The parameters of laser radiation are chosen to optimize the processes of photo-phacoablation and photo-phacodisruption. The vibrational frequencies of ultrasound are selected to optimize sono-fragmentation sono-cavitation. Both laser radiation and ultrasound energy are delivered in effective combinations to maximize the precise removal of cataractous lens material.

Abstract: A fluid retention assembly for use in association with an iontophoretic drug delivery device comprising: a matrix, wherein the matrix is fabricated from a hydroxylated polyvinyl acetal; a first excipient associated with the matrix, wherein the first excipient comprises a substantially non-ionic thickening agent; and a second excipient associated with the matrix, wherein the second excipient comprises a hydration enhancer. A method for preparing a fluid retention assembly for use in association with an iontophoretic drug delivery device comprising the steps of: providing a first excipient, wherein the first excipient comprises a substantially non-ionic thickening agent; providing a second excipient, wherein the second excipient comprises a hydration enhancer; preparing a solution of the first and second excipients in a solvent; soaking a matrix fabricated from a hydroxylated polyvinyl acetal in the prepared solution; and drying the matrix.

Abstract: An electromagnetically induced mechanical cutting mechanism provides accurate cutting and ablating operations on soft tissues such as skin. Electromagnetic energy is concentrated into moist air and/or atomized fluid particles above the skin and, subsequently, the electromagnetic energy is absorbed by the moisture and/or atomized fluid particles to impart disruptive forces onto the skin. The moist air and/or atomized fluid particles may be medicated.

Abstract: Myocardial revascularization is performed by an apparatus and method which forms channels in the myocardium from inside the ventricular cavity without penetrating the full thickness of the ventricular wall. A catheter has a fiber optic connected at its handling end to a laser, and terminates at the insertable end of the catheter. A servomotor controls the advancing of the fiber to stop positions relative to the catheter. At each stop position another channel is created. An aiming beam aids in directing the channel forming fiber end to different desired channel positions.

Abstract: A device for laser treatment of painful symptomatologies with a first laser source 1, a conveying device for conveying the laser energy to a hand unit 5, and optical structure 11, 13 for defocusing the laser beam.

Abstract: Disclosed herein is a method of treating mammalian, for example, human, skin afflicted with a sebaceous follicle disorder, for example, acne. The method involves cooling an exposed surface of a region afflicted with the disorder and applying light, for example, light from a coherent or incoherent light source, to the region. The applied light reduces the size and/or density of lesions associated with the disorder in the treated region, and can reduce or otherwise alleviate lesion-associated skin inflammation in the treated region. Cooling preserves the surface, for example, epidermis, of the skin. The method, therefore, is effective at treating the disorder while at the same time avoiding or minimizing thermal damage to the exposed surface of the skin.

Abstract: Photodynamic therapy (PDT), the light activation of methylene blue or benzoporphyrin derivatives to produce free-radicals, was shown in vivo to inhibit intimal hyperplasia (IH) and restenosis. The present invention provides an effective clinical approach for PDT treatment which modulates the vascular intervention injury healing response.

Abstract: A system and method for the treatment of ocular collagen connective tissue comprises identifying a portion of the ocular collagen connective tissue having a connector portion which transitions into the ciliary muscle and the lens of an eye. A source of energy is then directed at at least one selected site along the portion of the connective tissue, the amount of energy being sufficient to cause longitudinal shrinkage in the length of connective tissue.

Abstract: The invention relates to a method and a device for the superficial heating of tissue by means of a pulsed light source. According to the invention a series of light pulses is applied to the tissue surface. The first part of this series is configured such that the tissue surface and, by heat conduction, tissue areas situated below the tissue surface are rapidly heated to a defined target temperature without tissue removal. The subsequent part of the series results in oscillation of the temperature of the tissue areas located below the tissue surface around a value which is slightly lower than the target temperature.

Abstract: Apparatus and methods for electromagnetic skin treatment, including the removal of hair. Devices include pulsed light sources such as flashlamps for providing electromagnetic treatment of the skin, including hair removal. The devices and methods provide for the removal of large numbers of hairs at the same time, rather than on a hair by hair basis.

Abstract: A method for removing hairs from living skin is provided which includes steps of measuring with a colorimeter the color of the area of the skin where the hair is to be removed to obtain a color value, employing the color value to select an optimum range of laser energy necessary to kill hair follicles in the area yet minimize inflammatory reaction, and directing the laser energy of the optimum range at the skin area.

Abstract: Methods are provided for treating prostate glands or other targeted soft tissue using a solid-state laser. The laser can be operated to generate a pulsed output beam having pulse durations of between 0.1 and 500 milliseconds. The output beam is delivered to the targeted tissue through an optical fiber, preferably terminating in a side-firing probe or diffusing tip. By operating the laser in a long-duration pulse mode, charring of the targeted tissue is initiated quickly, thereby increasing ablation rates and reducing overall procedure time.

Abstract: Aging or damaged skin is treated by irradiating affected skin areas with an effective amount of blue and/or violet visible light having a wavelength of about 400 nm to about 500 nm. The light may be sunlight or artificial light, coherent or noncoherent, pulsed or continuous, of high or low energy, exposed generally or directed to target areas, or any combination of these. A variety of irradiation methods may be employed. In one embodiment, filtered sun or artificial light is used. This can be widely exposed to skin areas, or directed to discrete skin regions, particularly to areas especially susceptible to aging, e.g., the backs of hands and the periorbital and perioral areas of the face. In an alternate embodiment, light-emitting diodes are applied directly to discrete skin areas as needed as patches or thin sheets such as pliable masks. Green light (about 500 to about 590 nm) may be used as adjunct therapy with blue/violet light in some embodiments.

Abstract: Laser systems medical or cosmetic applications, comprising diode lasers or diode lasers with other solid state lasers which can deliver up to 30 cw or more, and which generally operate at more than wavelength within the range of 1000 to 1300 nm are presented. Individual emitter or emitter groups within the diode laser system can be powered independently. These laser systems provide maximum penetration depths for procedures such as Laser-induced Interstitial Tumor Therapy, alone or in conjunction with other therapies such as PhotoDynamic Therapy, chemotherapy, or radiation therapy. Where beneficial for the procedure, the operating wavelength of the system can be changed without interruption. In some variants, active tissue cooling at the distal end of the delivery fibers is incorporated as well as individual feedback loops to control and stabilize the temperature induced in the tissue.