Treating Or Preventing Abnormally High Heart Rate Patents (Class 607/14)
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Patent number: 9352163Abstract: A defibrillating system includes a processor coupled to a memory. The processor and the memory are configured to identify a treatment event associated with treatment of a victim with the defibrillating system, and transmit a representation of a portion of an ECG signal associated with the identified treatment event. In some cases, the processor and the memory are configured to identify the portion of the ECG signal associated with the identified treatment event. In some cases, the portion of the ECG signal is of a predetermined length of time having a start time and an end time based on a time associated with the identified treatment event.Type: GrantFiled: August 20, 2015Date of Patent: May 31, 2016Assignee: ZOLL Medical CorporationInventor: John Amann
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Patent number: 9289165Abstract: In general, the invention is directed to methods and devices for determining an ion concentration in the extracellular fluid of a patient. As examples, the ion may be one or more of potassium, sodium, chloride, or calcium. A system includes an electrode deployed in or near a tissue, such as a skeletal muscle, of the patient. A pulse generator supplies one or more stimulations to the tissue, and a sensor, such as an accelerometer, detects the response of the tissue to the stimulations. A processor determines a concentration of ions in the extracellular fluid as a function of the response. The system may detect an ion imbalance based upon the determined concentration of ions.Type: GrantFiled: October 15, 2014Date of Patent: March 22, 2016Assignee: Medtronic, Inc.Inventors: Orhan Soykan, Timothy H. Robinson, James K. Carney, Tara L. Nahey, Cygni Chan
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Patent number: 9269044Abstract: An event-driven neural network includes a plurality of interconnected core circuits is provided. Each core circuit includes an electronic synapse array has multiple digital synapses interconnecting a plurality of digital electronic neurons. A synapse interconnects an axon of a pre-synaptic neuron with a dendrite of a post-synaptic neuron. A neuron integrates input spikes and generates a spike event in response to the integrated input spikes exceeding a threshold. Each core circuit also has a scheduler that receives a spike event and delivers the spike event to a selected axon in the synapse array based on a schedule for deterministic event delivery.Type: GrantFiled: August 14, 2012Date of Patent: February 23, 2016Assignees: International Business Machines Corporation, Cornell UniversityInventors: Filipp Akopyan, John V. Arthur, Rajit Manohar, Paul A. Merolla, Dharmendra S. Modha, Alyosha Molnar, William P. Risk, III
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Patent number: 9265432Abstract: Methods, systems, and devices for signal analysis in an implanted cardiac monitoring and treatment device such as an implantable cardioverter defibrillator. In some examples, captured data including detected events is analyzed to identify likely overdetection of cardiac events. In some illustrative examples, when overdetection is identified, data may be modified to correct for overdetection, to reduce the impact of overdetection, or to ignore overdetected data. Several examples emphasize the use of morphology analysis using correlation to static templates and/or inter-event correlation analysis.Type: GrantFiled: May 23, 2014Date of Patent: February 23, 2016Assignee: CAMERON HEALTH, INC.Inventors: Jay A. Warren, Rick Sanghera, Venugopal Allavatam, Surekha Palreddy
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Patent number: 9262581Abstract: A system for noninvasively determining at least one physiological characteristic of a patient may include at least one computer system configured to, using a three-dimensional surface mesh model created using patient-specific imaging data, create a three-dimensional combined surface and volume mesh model, including at least a first model portion that has a different spatial resolution than at least a second model portion. The computer system may be further configured to input the three-dimensional surface and volume mesh model into a fluid simulation system and determine a measurement of the physiological characteristic, using the fluid simulation system.Type: GrantFiled: September 24, 2012Date of Patent: February 16, 2016Assignee: HeartFlow, Inc.Inventors: Jin Kim, Michael Singer
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Patent number: 9227069Abstract: An implantable medical device senses atrial depolarizations having associated refractory periods thereafter and delivers electrical stimulation pulses during the associated refractory periods to stimulate the atrioventricular (AV) node to cause a prolonged conduction time of an atrial depolarization to a ventricular chamber. The device delivers a pacing pulse to a first ventricular chamber during the prolonged conduction time to cause a contraction and associated refractory period of the first ventricular chamber, the first ventricular chamber contraction occurring earlier than a contraction of a second ventricular chamber.Type: GrantFiled: March 15, 2011Date of Patent: January 5, 2016Assignee: Medtronic, Inc.Inventors: Vinayakrishnan Rajan, Richard N. M. Cornelussen, Berthold Stegemann, Lilian Kornet
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Patent number: 9211413Abstract: The disclosure herein relates generally to methods for treating heart conditions using vagal stimulation, and further to systems and devices for performing such treatment. Such methods may include monitoring physiological parameters of a patient, detecting cardiac conditions, and delivering vagal stimulation (e.g., electrical stimulation to the vagus nerve or neurons having parasympathetic function) to the patient to treat the detected cardiac conditions.Type: GrantFiled: July 14, 2014Date of Patent: December 15, 2015Assignee: Medtronic, Inc.Inventors: Paul D. Ziegler, Lilian Kornet, Xiaohong Zhou, Richard N. M. Cornelussen, Robert Stadler, Eduardo Warman, Karen J. Kleckner, Alberto Della Scala
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Patent number: 9211412Abstract: Various aspects of the present subject matter relate to a method. According to various method embodiments, cardiac activity is detected, and neural stimulation is synchronized with a reference event in the detected cardiac activity. Neural stimulation is titrated based on a detected response to the neural stimulation. Other aspects and embodiments are provided herein.Type: GrantFiled: March 13, 2013Date of Patent: December 15, 2015Assignee: Cardiac Pacemakers, Inc.Inventors: Aaron R. McCabe, Imad Libbus, Yi Zhang, Paul A. Haefner, Alok S. Sathaye, Anthony V. Caparso, M. Jason Brooke
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Patent number: 9183352Abstract: A method, a system and an arrangement for predicting at least one system event and a corresponding computer program and a corresponding computer-readable storage medium are configured so that it is possible to predict a system event based on trends in observables over a certain period of time prior to the event occurring. One example of a system event is the failure of a system because the abnormal behavior of a component is reflected in irregularities in one or a plurality of observables. Another example of a system event is the early recognition or pre-acute prediction of a specific critical condition of a patient.Type: GrantFiled: April 8, 2010Date of Patent: November 10, 2015Assignee: BIOTRONIK CRM Patent AGInventors: Sergey Berdyshev, Manuel Ebert, Thomas Kraemer, Wolfgang Meyer
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Patent number: 9179974Abstract: Helical push wire electrodes are provided. The electrodes may create a continuous helical lesion. One or more electrodes may wind around a support section and create a set of helixes having fixed ends and hitches. Pushing or pulling an end of the electrode transforms the electrodes between a delivery configuration and a deployed configuration such that the set of helixes expand or contract axially. Different portions of the electrodes may be surrounded by sleeves. The sleeves may regulate how the wires transform and provide insulation. Various insulation configurations of the electrodes may provide creations of discrete lesions, efficient energy delivery and reduced power consumption.Type: GrantFiled: April 25, 2013Date of Patent: November 10, 2015Assignee: Medtronic Ardian Luxembourg S.a.r.l.Inventors: Vincent W. Ku, Andrew E. Wu
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Patent number: 9162074Abstract: Methods, systems, and devices for signal analysis in an implanted cardiac monitoring and treatment device such as an implantable cardioverter defibrillator. In illustrative examples, captured data including detected events is analyzed to identify likely overdetection of cardiac events. In some illustrative examples, when overdetection is identified, data may be modified to correct for overdetection, to reduce the impact of overdetection, or to ignore overdetected data. New methods for organizing the use of morphology and rate analysis in an overall architecture for rhythm classification and cardiac signal analysis are also discussed.Type: GrantFiled: November 24, 2014Date of Patent: October 20, 2015Assignee: CAMERON HEALTH, INC.Inventors: Venugopal Allavatam, Surekha Palreddy, Rick Sanghera, Jay A. Warren
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Patent number: 9149637Abstract: Methods and devices for adjusting therapy delivery decisions in an implantable cardiac stimulus device by observing cardiac activity following an initial identification of a treatable condition. In some examples, cardiac activity that appears benign is quantified and a therapy confirmation threshold is adjusted according to how much apparently benign cardiac activity is seen after an initial identification of a treatable condition. In other examples, a new threshold is applied following the initial identification of treatable condition, removing historical data preceding the initial identification from subsequent therapy delivery decisions.Type: GrantFiled: June 29, 2010Date of Patent: October 6, 2015Assignee: CAMERON HEALTH, INC.Inventors: Jay A. Warren, Rick Sanghera, Venugopal Allavatam
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Patent number: 9149639Abstract: According to some method embodiments, a left pulmonary artery electrode is positioned in a left pulmonary artery, and the left pulmonary artery electrode is used to sense atrial activity, or capture cardiac tissue, or deliver neural stimulation. According to some method embodiments, a right pulmonary artery electrode is positioned in a right pulmonary artery and a left pulmonary artery electrode is positioned in a left pulmonary artery, the right pulmonary artery electrode is used to sense atrial activity, or capture cardiac tissue, or deliver neural stimulation, and the left pulmonary artery electrode is used to sense atrial activity, or capture cardiac tissue, or deliver neural stimulation.Type: GrantFiled: April 2, 2013Date of Patent: October 6, 2015Assignee: Cardiac Pacemakers, Inc.Inventors: Yongxing Zhang, Yunlong Zhang
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Patent number: 9144390Abstract: A defibrillating system includes a processor coupled to a memory. The processor and the memory are configured to identify a treatment event associated with treatment of a victim with the defibrillating system, and transmit a representation of a portion of an ECG signal associated with the identified treatment event. In some cases, the processor and the memory are configured to identify the portion of the ECG signal associated with the identified treatment event. In some cases, the portion of the ECG signal is of a predetermined length of time having a start time and an end time based on a time associated with the identified treatment event.Type: GrantFiled: September 27, 2013Date of Patent: September 29, 2015Inventor: John Amann
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Patent number: 9138160Abstract: Embodiments of the invention provide methods for the detection and treatment of atrial fibrillation (AF) and related conditions. One embodiment provides a method comprising measuring electrical activity of the heart using electrodes arranged on the heart surface to define an area for detecting aberrant electrical activity (AEA) and then using the measured electrical activity (MEA) to detect foci of AEA causing AF. A pacing signal may then be sent to the foci to prevent AF onset. Atrial wall motion characteristics (WMC) may be sensed using an accelerometer placed on the heart and used with MEA to detect AF. The WMC may be used to monitor effectiveness of the pacing signal in preventing AF and/or returning the heart to normal sinus rhythm (NSR). Also, upon AF detection, a cardioversion signal may be sent to the atria using the electrodes to depolarize an atrial area causing AF and return the heart to NSR.Type: GrantFiled: March 25, 2014Date of Patent: September 22, 2015Assignee: InCube Labs, LLCInventor: Mir Imran
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Patent number: 9119965Abstract: Techniques are provided for controlling spinal cord stimulation (SCS) or other forms of neurostimulation. In one example, SCS treatment is delivered to a patient and nerve impulse firing signals are sensed along the spinal cord following the SCS treatment. The nerve impulse signals are analyzed to determine whether the signals are associated with effective SCS and then the delivery of additional SCS is controlled to improve SCS efficacy. For example, the nerve impulse signals can be analyzed to determine whether the signals are consistent with a positive patient mood associated with pain mitigation and, if not, SCS control parameters are adjusted to improve the efficacy of the SCS in reducing pain. In other examples, heart rate variability (HRV) is also used to control SCS. Still further, adjustments may be made to SCS control parameters to improve antiarrhythmic or sympatholytic effects associated with SCS. Techniques employing baseline/target calibration procedures are also described.Type: GrantFiled: April 9, 2012Date of Patent: September 1, 2015Assignee: Pacesetter, Inc.Inventors: Cecilia Qin Xi, Stuart Rosenberg
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Patent number: 9108058Abstract: A system for stimulating a left phrenic nerve and a right phrenic nerve of a patient includes a signal generator to produce stimulation signals; a lead structure configured for insertion into a venous system of the patient, the lead structure having a plurality of leads to receive stimulation signals from the signal generator; a plurality of second pairs of electrodes on the lead structure proximate a distal portion of the lead structure and configured to receive stimulation signals from at least one of the plurality of leads; a plurality of first pairs of electrodes on the lead structure proximal of the plurality of second pairs of electrodes and configured to receive stimulation signals from at least one of the plurality of leads; and a control system programmed to (a) select a first stimulation pair of electrodes from the plurality of first pairs of electrodes to stimulate the left phrenic nerve, and (b) select a second stimulation pair of electrodes from the plurality of second pairs of electrodes to stimType: GrantFiled: July 31, 2014Date of Patent: August 18, 2015Assignee: Simon Fraser UniversityInventor: Joaquin Andres Hoffer
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Patent number: 9084898Abstract: Various system embodiments comprise at least one sensor input adapted to receive at least one sensed signal associated with a tachyarrhythmia, a feature set extractor adapted to extract at least two features from the at least one sensed signal associated with the tachyarrhythmia, a feature set generator adapted to form a feature set using the at least two features extracted by the feature set extractor, at least one generator adapted for use to selectively apply an anti-tachycardia pacing (ATP) therapy and a neural stimulation (NS) therapy, and a controller adapted to respond to the feature set. The controller is adapted to initiate the NS therapy when the feature set corresponds to criteria for applying the NS therapy to modify the tachyarrhythmia, and initiate the ATP therapy to terminate the modified tachyarrhythmia. Other aspects and embodiments are provided herein.Type: GrantFiled: August 8, 2012Date of Patent: July 21, 2015Assignee: Cardiac Pacemakers, Inc.Inventor: Dan Li
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Patent number: 9078574Abstract: Techniques are provided for use by implantable medical devices such as pacemakers or by external systems in communication with such devices. An intracardiac electrogram (IEGM) is sensed within a patient in which the device is implanted using a cardiac signal sensing system. Cardiac events of interest such as arrhythmias, premature atrial contractions (PACs), premature ventricular contractions (PVCs) and pacemaker mediated tachycardias (PMTs) are detected within the patient using event detection systems and then portions of the IEGM representative of the events of interest are recorded in device memory. Subsequently, during an off-line or background analysis, the recorded IEGM data is retrieved and analyzed to identify false detections. In response to false detections, the cardiac signal sensing systems and/or the event detection systems of the implantable device are selectively adjusted or reprogrammed to reduce or eliminate any further false detections, including false-positives or false-negatives.Type: GrantFiled: December 20, 2013Date of Patent: July 14, 2015Assignee: Pacesetter, Inc.Inventors: Jeffery D. Snell, Euljoon Park
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Publication number: 20150148854Abstract: A non-invasive bodily-attached ambulatory medical monitoring and treatment device with pacing is provided. The noninvasive ambulatory pacing device includes a battery, at least one therapy electrode coupled to the battery, a memory storing information indicative of a patient's cardiac activity, and at least one processor coupled to the memory and the at least one therapy electrode. The at least one processor is configured to identify a cardiac arrhythmia within the information and execute at least one pacing routine to treat the identified cardiac arrhythmia.Type: ApplicationFiled: January 30, 2015Publication date: May 28, 2015Inventors: Jason T. Whiting, Thomas E. Kaib, Rachel H. Carlson, Gregory R. Frank
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Method and system to select a neurostimulation system configuration based on cardiac rhythm feedback
Patent number: 9037236Abstract: Methods and systems are provided to control a configuration of a neural stimulation (NS) system having an NS device coupled to an NS lead. The methods and systems change between configurations of the NS system and collect cardiac signals from a patient that are representative of cardiac rhythms experienced by the patient over a period of time and in connection with multiple NS configurations. The methods and systems derive, from the cardiac signals, characteristic values for at least one physiologic characteristic indicative of at least one of normal and abnormal cardiac rhythms in connection with the multiple NS configurations; and select, from the multiple NS configurations, an NS operating configuration to be used by the NS system based on the characteristic values.Type: GrantFiled: June 29, 2012Date of Patent: May 19, 2015Assignee: Pacesetter, Inc.Inventors: Cecilia Qin Xi, Lanitia Ness, Stuart Rosenberg -
Patent number: 9031649Abstract: An implantable medical device (IMD) identifies suspected non-lethal ventricular arrhythmia, and takes one or more actions in response to the identification to avoid or delay delivery of a defibrillation or cardioversion shock. The IMD employs number of intervals to detect (NID) thresholds for detection of ventricular arrhythmias. When a NID threshold is met, the IMD determines whether the ventricular rhythm is a suspected non-lethal rhythm despite satisfying a NID threshold. In some embodiments, the IMD increases the NID threshold, i.e., extends the time for detection, in response to identifying a rhythm as a suspected non-lethal rhythm, and monitors subsequent ventricular beats to determine if the increased NID threshold is met before detecting a ventricular arrhythmia and delivering therapy. The IMD can determine whether a rhythm is a suspected non-lethal arrhythmia by, for example, comparing the median ventricular cycle length (VCL) to the median atrial cycle length (ACL).Type: GrantFiled: November 25, 2013Date of Patent: May 12, 2015Assignee: Medtronic, Inc.Inventor: Kevin T. Ousdigian
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Patent number: 8996101Abstract: A method and device for detecting a cardiac event that includes sensing cardiac electrical signals representative of electrical activity of a heart of a patient, detecting the cardiac event in response to the sensed cardiac signals, determining an indication of signal reliability corresponding to the sensed cardiac signals as being one of a reliable signal and a not reliable signal, and switching operation of the device between a first mode of determining whether the sensed signal is one of treatable and not treatable and a second mode of determining whether the sensed signal is one of treatable and not treatable in response to the determined indication of signal reliability.Type: GrantFiled: April 27, 2012Date of Patent: March 31, 2015Assignee: Medtronic, Inc.Inventors: Xusheng Zhang, Teresa A. Whitman, Paul J. DeGroot, Mark L. Brown, Jeffrey M. Gillberg
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Publication number: 20150088218Abstract: A method to provide electrical stimulation therapy to stabilize ventricular rate of a heart during episodes of atrial fibrillation. The stimulation therapy may be a plurality of stimulation pulses delivered to the AV node during the AV node refractory period following the sensing of an atrial event.Type: ApplicationFiled: December 2, 2014Publication date: March 26, 2015Inventors: Euljoon Park, You-Ho Kim, Taraneh Ghaffari Farazi
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Publication number: 20150088217Abstract: An implantable cardiac stimulation device provides electrical stimulation therapy to stabilize the ventricular rate of a heart during episodes of atrial fibrillation. The stimulation therapy may be a plurality of sub-threshold stimulation pulses delivered to capture AV node vagal innervations following the detection of atrial fibrillation.Type: ApplicationFiled: December 2, 2014Publication date: March 26, 2015Inventors: Euljoon Park, You-Ho Kim, Taraneh Ghaffari Farazi
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Publication number: 20150088216Abstract: A system including a programmable implantable monitoring device and a programmer for programming the device and a method of use thereof. The programmer may be configured to transmit programming commands responsive to entry of a reason for monitoring to the implantable device including a prioritization of an arrhythmia storage criterion. The implantable may be configured to thereafter store and/or transmit records of the arrhythmia according to the prioritization. The programmer may be configured to transmit the patient's age to the implantable device and the implantable may be configured to thereafter apply arrhythmia detection criteria based upon the patient's age.Type: ApplicationFiled: April 9, 2014Publication date: March 26, 2015Inventors: Charles R Gordon, Paul G Krause, Grant Alan Neitzell, Shantanu Sarkar, Ryan Wyszynski
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Patent number: 8983600Abstract: A cardiac pacing system introduces a transitional period when pacing mode changes, such as when pacing starts and stops, or when one or more pacing parameter values change substantially. For each pacing parameter that changes substantially when the pacing mode changes, its value is adjusted incrementally over the transitional period to protect the heart from potentially harmful conditions associated with an abrupt change in the value of that pacing parameter.Type: GrantFiled: April 28, 2010Date of Patent: March 17, 2015Assignee: Cardiac Pacemakers, Inc.Inventors: Allan C. Shuros, Eric A. Mokelke
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Patent number: 8965505Abstract: A medical device and method for detecting and classifying cardiac rhythm episodes that includes a sensing module to sense cardiac events, a therapy delivery module, and a detection module configured to determine intervals between the sensed cardiac events, determine a predetermined cardiac episode is occurring in response to the determined intervals, determine whether a ventricular rate is greater than an atrial rate in response to the determined intervals, determine whether undersensing is occurring in response to the ventricular rate being greater than the atrial rate, perform a supraventricular tachycardia (SVT) discrimination analysis in response to undersensing occurring, and control the therapy delivery module to deliver therapy in response to the SVT discrimination analysis.Type: GrantFiled: March 15, 2013Date of Patent: February 24, 2015Assignee: Medtronic, Inc.Inventors: Sandra B. Charlton, Troy E. Jackson, Benjamin P. Rhodes
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Patent number: 8965504Abstract: An implantable sensor circuit can be configured to generate a first sensor signal representative of mechanical activation of a first chamber of a heart of a subject and a second sensor signal representative of mechanical activation of a second chamber of the heart. A chamber synchrony measurement circuit can be configured to generate a measure of synchrony of the mechanical activations of the first heart chamber and the second heart chamber using the first and second sensor signals, a tachyarrhythmia detector circuit, and a control circuit. The control circuit can be configured to receive an indication of a detected episode of tachyarrhythmia, and to initiate, select, or adjust a device-based therapy at least in part using the measure of synchrony of the mechanical activations in response to the tachyarrhythmia detection.Type: GrantFiled: February 28, 2013Date of Patent: February 24, 2015Assignee: Cardiac Pacemakers, Inc.Inventor: Dan Li
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Patent number: 8965495Abstract: An implantable electronic therapy device, having a therapy unit, a heart rate capturing unit, a contractility determination unit, and an evaluation and control unit. The therapy unit delivers an antitachycardiac therapy. The heart rate capturing unit determines a ventricular heart rate from an input signal, and the contractility determination unit generates from an input signal, a contraction signal reflecting a contractility of a ventricle. The evaluation and control unit is connected to the therapy unit, the heart rate capturing unit, and the contractility determination unit actuates the therapy unit to administer an antitachycardiac therapy when the heart rate capturing unit detects an increase in the heart rate above a specified threshold value and the contractility determination unit supplies a contraction signal which is not physiologically adequate for the increase in the heart rate.Type: GrantFiled: August 1, 2011Date of Patent: February 24, 2015Assignee: Biotronik Se & Co. KGInventor: Thomas Doerr
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Patent number: 8965503Abstract: In various method embodiments, a supraventricular arrhythmia event is detected, and a supraventricular arrhythmia treatment, including neural stimulation to elicit a sympathetic response, is delivered in response to a detected supraventricular arrhythmia event. Some embodiments detect a precursor for a supraventricular arrhythmia episode, and deliver prophylactic neural stimulation to avoid the supraventricular arrhythmia event. Some embodiments detect a supraventricular arrhythmia episode, and deliver therapeutic neural stimulation for the supraventricular arrhythmia event.Type: GrantFiled: July 23, 2012Date of Patent: February 24, 2015Assignee: Cardiac Pacemakers, Inc.Inventor: Imad Libbus
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Publication number: 20150045846Abstract: For terminating a high frequency arrhythmic electric state of a heart an electric signal representative of the present electric state of the heart is obtained. From the electric signal a dominant frequency of the present electric state is determined, and from the dominant frequency it is determined whether the present electric state of the heart is a high frequency arrhythmic electric state displaying at least one rotating wave. Further, a dominance level indicative of how dominant the dominant frequency is in the high frequency arrhythmic electric state is determined from the electric signal. Depending on the at least one dominant frequency, at least one series of electric pulses at intervals is generated. The electric pulses are applied to the heart starting at a point in time at which the dominance level exceeds a predefined threshold value for the heart being in a determined high frequency arrhythmic electric state.Type: ApplicationFiled: October 23, 2014Publication date: February 12, 2015Inventors: Stefan Luther, Eberhard Bodenschatz, Valentin Krinski, Robert Gilmour, Flavio Fenton
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Publication number: 20150039041Abstract: This document discusses, among other things, a modular antitachyarrhythmia therapy system. In an example, a modular antitachyarrhythmia system includes at least two separate modules that coordinate delivery an antitachyarrhythmia therapy, such as defibrillation therapy. In another example, a modular antitachyarrhythmia therapy system includes a sensing module, an analysis module, and a therapy module.Type: ApplicationFiled: October 9, 2014Publication date: February 5, 2015Inventors: Joseph M. Smith, Richard Milon Dujmovic, JR.
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Patent number: 8948867Abstract: In connection with capture detection for a heart chamber with backup pacing in a contralateral heart chamber, a cardiac signal of the first heart chamber is sensed following delivery of a pacing pulse. The cardiac response of the first heart chamber to the pacing pulse is classified based on one or more features of the sensed cardiac signal. A backup pacing pulse is delivered to a second heart chamber contralateral to the first heart chamber. For example, the timing of the delivery of the backup pacing pulse may be based on the expected or detected timing of the features used to classify the cardiac pacing response. The backup pace may be delivered within a detection window used for sensing the features indicative of the cardiac pacing response.Type: GrantFiled: September 14, 2006Date of Patent: February 3, 2015Assignee: Cardiac Pacemakers, Inc.Inventors: Alok Sathaye, M. Jason Brooke
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Publication number: 20150032170Abstract: Apparatus and method for treating an arrhythmia in a patient using an electrotherapy device such as a subcutaneous pacing device. The device applies a series of electrotherapy pulses in response to the presence of the arrhythmia. Various provisions are disclosed for mitigating pain or discomfort as a result of the electrotherapy pulses.Type: ApplicationFiled: July 30, 2014Publication date: January 29, 2015Inventors: Byron L. Gilman, Mark W. Kroll
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Publication number: 20150025592Abstract: An implantable heart therapy device connected to at least one right-ventricular electrode and one left-ventricular electrode that sense and stimulate the heart. The at least one right-ventricular and left-ventricular electrodes are each connected to a tachycardia identification unit, wherein the identification unit identifies ventricular tachycardias, and simultaneously evaluates the heart rate at the right-ventricular and at the left-ventricular electrodes. The implantable heart therapy device includes a right-ventricular stimulation unit that delivers antitachycardia stimulation to the right-ventricular electrode, a left-ventricular stimulation unit that delivers antitachycardia stimulation to the left-ventricular electrode, and a therapy control unit that assigns the stimulation location for the antitachycardia stimulation to the slower ventricle side if a dissimilar tachycardia is present.Type: ApplicationFiled: July 3, 2014Publication date: January 22, 2015Applicant: BIOTRONIK SE & CO. KGInventors: Thomas DOERR, Andreas Kucher
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Patent number: 8929983Abstract: Cardioprotective pre-excitation pacing may be applied to stress or de-stress a particular myocardial region delivering of pacing pulses in a manner that causes a dyssynchronous contraction. Such dyssynchronous contractions are responsible for the desired cardioprotective effects of pre-excitation pacing. A method and device for applying reverse hysteresis and mode switching to the delivery of such cardioprotective pacing are described.Type: GrantFiled: November 9, 2009Date of Patent: January 6, 2015Assignee: Cardiac Pacemakers, Inc.Inventors: Shantha Arcot-Krishnamurthy, Gary T. Seim, Kent Lee, Yanting Dong, Allan C. Shuros, David L. Whitehouse
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Patent number: 8914106Abstract: A medical device and method for detecting and classifying cardiac rhythm episodes that includes a sensing module to sense cardiac events; a therapy delivery module, and a detection module configured to determine intervals between the sensed cardiac events, determine a predetermined cardiac episode is occurring in response to the determined intervals, determine whether a ventricular rate is greater than an atrial rate in response to the determined intervals, determine whether oversensing is occurring in response to the ventricular rate being greater than the atrial rate, adjust the determined intervals in response to oversensing occurring to generate an adjusted ventricular rate, determine whether the cardiac episode is occurring in response to the adjusted ventricular rate, perform a supraventricular tachycardia (SVT) discrimination analysis in response to the cardiac episode occurring in response to the adjusted ventricular rate, and control the therapy delivery module to deliver therapy in response to the SType: GrantFiled: March 15, 2013Date of Patent: December 16, 2014Assignee: Medtronic, Inc.Inventors: Sandra B. Charlton, Troy E. Jackson, Benjamin P. Rhodes
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Patent number: 8909337Abstract: Various aspects of the present subject matter provide devices and methods to treat AV-conducted ventricular tachyarrhythmia (AVCVT). According to various embodiments of the method, an AVCVT is sensed, an IVC-LA fat pad is stimulated when the AVCVT is sensed to block AV conduction, and bradycardia support pacing is provided while the IVC-LA fat pad is stimulated. Other aspects and embodiments are provided herein.Type: GrantFiled: May 17, 2012Date of Patent: December 9, 2014Assignee: Cardiac Pacemakers, Inc.Inventors: Julia Moffitt, Andrew P. Kramer, Imad Libbus
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Patent number: 8903490Abstract: In various method embodiments for classifying an arrhythmia, a characteristic of a ventricle is sensed before delivering a diagnostic neural stimulation. The diagnostic neural stimulation is delivered, and the characteristic of the ventricle is sensed while delivering the diagnostic neural stimulation. The sensed characteristic of the ventricle before and during the diagnostic neural stimulation is used to classify the arrhythmia as either a supraventricular tachyarrhythmia (SVT) or a ventricular tachycardia (VT). According to various embodiments, the characteristic of the ventricle is ventricular rate, similarity values of sensed ventricular morphology to a normal sinus rhythm (NSR), or ventricular hemodynamics. Various embodiments use ventricular rate regularity before and during the diagnostic neural stimulation to classify an SVT as atrial fibrillation (AF) or as another SVT.Type: GrantFiled: February 2, 2011Date of Patent: December 2, 2014Assignee: Cardiac Pacemakers, Inc.Inventor: Dan Li
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Publication number: 20140350624Abstract: A rules engine acquires sensor data from sensors applied to the heart to determine the presence of a rapid heartbeat. The rules engine applies rules to the sensor data to determine whether to deliver an electrical waveform to a vagus nerve. The rules engine further determines whether an electrical waveform should be applied to the heart and, if so, the type of electrical waveform.Type: ApplicationFiled: May 23, 2014Publication date: November 27, 2014Applicant: MR3 Medical, LLCInventor: Morton M. MOWER
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Patent number: 8886309Abstract: For terminating a high frequency arrhythmic electric state of a biological tissue an electric signal representative of the present electric state of the biological tissue is obtained. From the electric signal a dominant frequency of the present electric state is determined, and from the dominant frequency it is determined whether the present electric state of the biological tissue is a high frequency arrhythmic electric state. Further, a dominance level indicative of how dominant the dominant frequency is in the high frequency arrhythmic electric state is determined from the electric signal. Depending on the at least one dominant frequency, at least one series of electric pulses at intervals is generated. The electric pulses are applied to the biological tissue starting at a point in time at which the dominance level exceeds a predefined threshold value for the biological tissue being in a determined high frequency arrhythmic electric state.Type: GrantFiled: December 13, 2013Date of Patent: November 11, 2014Assignees: Max-Planck-Gesellschaft zur Foerderung der Wissenschaften E.V., Cornell UniversityInventors: Stefan Luther, Eberhard Bodenschatz, Valentin Krinski, Robert Gilmour, Flavio H. Fenton
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Patent number: 8886296Abstract: The present disclosure is directed to the classification of cardiac episodes using an algorithm. In various examples, an episode classification algorithm evaluates electrogram signal data to determine whether T-wave oversensing has occurred. The T-wave oversensing analysis may include, for example, identifying beat runs within the cardiac episode whether the beats within the run have at least one characteristic that alternates beat to be or clustering beats within the cardiac episode based on beat to beat interval length. The T-wave oversensing determination may be based on probabilistic analysis in some examples.Type: GrantFiled: October 14, 2011Date of Patent: November 11, 2014Assignee: Medtronic, Inc.Inventor: Amisha S. Patel
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Patent number: 8874208Abstract: Methods and apparatus for a three-stage ventricular cardioversion and defibrillation therapy that treats ventricular tachycardia and fibrillation at low energy levels. An implantable therapy generator adapted to generate and selectively deliver a three-stage ventricular therapy and at least two leads operably each having at least one electrode adapted to be positioned proximate the ventricle of the patient. The device is programmed to deliver a three-stage therapy via both a far-field configuration and a near-field configuration of the electrodes upon detection of a ventricular arrhythmia. The three-stage therapy includes a first stage for unpinning of one or more singularities associated with the ventricular arrhythmia, a second stage for anti-repinning of the one or more singularities, both of which are delivered via the far-field configuration of the electrodes, and a third stage for extinguishing of the one or more singularities associated delivered via the near-field configuration of the electrodes.Type: GrantFiled: January 12, 2012Date of Patent: October 28, 2014Assignee: The Washington UniversityInventors: Igor R. Efimov, Wenwen Li, Ajit Janardhan
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Patent number: 8862214Abstract: A system is provided which processes cardiac condition data representative of heart electrical signals to identify a cardiac condition. An acquisition processor is conditioned for acquiring data representing a sequence of successive pulses of a type of electrical heart waveform of a patient. A computation processor is electrically coupled to the acquisition processor and is conditioned for calculating a pulse interval irregularity measure based on a sum of time interval differences occurring between pairs of successive pulses of the sequence of successive pulses and excluding time interval differences exceeding a predetermined maximum threshold from the sum. The computation processor is further conditioned to compare a calculated pulse interval irregularity measure with a predetermined irregularity measure threshold.Type: GrantFiled: April 2, 2009Date of Patent: October 14, 2014Assignee: Draeger Medical Systems, Inc.Inventor: Alireza Ghodrati
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Patent number: 8855763Abstract: A cardiac rhythm management (CRM) system includes an implantable medical device that delivers anti-tachyarrhythmia therapies including ATP. When a tachyarrhythmia episode is detected, the implantable medical device analyzes the morphology of a cardiac signal to determine whether and/or when to deliver an ATP therapy. In various embodiments, the implantable medical device produces morphological parameters indicative of the likeliness of success of the ATP therapy and selects an anti-tachyarrhythmia therapy mode based on the morphological parameters. In various embodiments, the implantable medical device also controls the timing of the ATP therapy delivery using morphological features of the cardiac signal to maximize the probability that the ATP therapy is delivered into an ATP window during which a tachyarrhythmia episode can be effectively terminated by pacing.Type: GrantFiled: March 31, 2011Date of Patent: October 7, 2014Assignee: Cardiac Pacemakers, Inc.Inventor: Dan Li
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Patent number: 8855762Abstract: A pacing system delivers cardiac protection pacing to protect the heart from injuries associated with ischemic events. The pacing system detects an ischemic event and, in response, initiates one or more cardiac protection pacing sequences each including alternative pacing and non-pacing periods. In one embodiment, the pacing system initiates cardiac protection pacing sequences including at least one postconditioning sequence to protect the heart from a detected ischemic event and a plurality prophylactic preconditioning sequences to protect the heart from probable future ischemic events.Type: GrantFiled: December 20, 2012Date of Patent: October 7, 2014Assignee: Cardiac Pacemakers, Inc.Inventors: Tamara Colette Baynham, Yi Zhang, Joseph M. Pastore
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Publication number: 20140275928Abstract: A device adapted to attach to a subject for detecting an ECG signal of the subject. The device includes a first, a second, and a third electrode, where the electrodes form an orthogonal configuration. Two channels of ECG data can be obtained using a common electrode, and can be further combined to obtain a further channel using vector mathematics. The channel combination can be performed at vector angles suitable for optimizing the detection of various features of the ECG spectra of the subject. A method of using an implantable cardiac device together with surface-attached wireless sensor(s) is also provided where the acquired data from the implantable cardiac device and from the surface-attached wireless sensor(s) are both used for diagnosing patient's heart conditions and administering appropriate therapies.Type: ApplicationFiled: March 17, 2014Publication date: September 18, 2014Applicant: Peerbridge Health, Inc.Inventors: Angelo Joseph Acquista, Avi Kometz, Leung-Hang Ma, John Shambroom
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Publication number: 20140277232Abstract: A patient suffering from congestive heart failure is at increased risk of cardiac arrhythmogenesis during sleep, particularly if experiencing central sleep apnea as a co-morbidity. Low intensity peripheral neurostimulation therapies that target imbalance of the autonomic nervous system have been shown to improve clinical outcomes. Thus, bi-directional autonomic regulation therapy is delivered to the cervical vagus nerve at an intensity that is insufficient to elicit pathological or acute physiological side effects and without the requirement of an enabling physiological feature or triggering physiological marker. The patient's physiology is monitored to identify periods of sleep. In one embodiment, upon sensing a condition indicative of tachyarrhythmia following a period of bradycardia, as naturally occurs during sleep, an enhanced “boost” dose of bi-directional neural stimulation intended to “break” the tachyarrhythmic condition is delivered.Type: ApplicationFiled: March 14, 2013Publication date: September 18, 2014Applicant: Cyberonics, IncInventors: Imad LIBBUS, Badri AMURTHUR, Bruce H. KENKNIGHT
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Patent number: 8838240Abstract: Systems and methods provide for sensing, during an event of tachycardia, hemodynamic signals concurrently from at least two spatially separated locations within a patient, and quantifying a spatial relationship between the hemodynamic signals. Hemodynamic stability or state of the patient during the tachycardia event is determined based at least in part on the quantified spatial relationship. One or more anti-tachycardia therapies to treat the tachycardia may be selected based at least in part on the determined stability or state of patient hemodynamics, and the selected one or more anti-tachycardia therapies may be delivered to treat the tachycardia. The hemodynamic signals may comprise at least two, or a mixed combination, of cardiac impedance signals, cardiac chamber pressure signals, arterial pressure signals, heart sounds; and acceleration signals.Type: GrantFiled: September 10, 2008Date of Patent: September 16, 2014Assignee: Cardiac Pacemakers Inc.Inventors: Dan Li, Krzysztof Siejko, Abhilash Patangay