Physical Activity Patents (Class 607/19)
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Patent number: 7869877Abstract: An implantable cardiac device is configured and programmed to assess a patient's cardiopulmonary function by evaluating the patient's heart rate response. Such evaluation may be performed by computing a heart rate response slope, defined as the ratio of an incremental change in intrinsic heart rate to an incremental change in measured activity level. The heart rate response slope may then be compared with a normal range to assess the patient's functional status.Type: GrantFiled: September 10, 2007Date of Patent: January 11, 2011Assignee: Cardiac Pacemakers, Inc.Inventors: Veerichetty Kadhiresan, Donald Hopper, Richard Fogoros, Lemont Baker
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Patent number: 7869878Abstract: An implantable cardiac stimulation device provides an intracardiac electrogram with reduced respiratory modulation effect. The device includes a sensing circuit that senses cardiac activity and provides an intracardiac electrogram signal extending over a plurality of cardiac cycles, a respiration monitor that monitors respiration associated with the sensed cardiac activity, and a cardiac cycle selector that selects a set of intracardiac electrogram cardiac cycles of the plurality of cardiac cycles in response to the monitored respiration. A processing circuit processes the selected set of intracardiac electrogram cardiac cycles to provide the intracardiac electrogram with reduced respiratory modulation effect.Type: GrantFiled: October 6, 2005Date of Patent: January 11, 2011Assignee: Pacesetter, Inc.Inventor: Steve Koh
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Patent number: 7848811Abstract: A system and method determines the posture of a body. The system is first calibrated by attaching it to, or implanted it into, a body, placing the body in particular postures, and generating spectral signatures for each of those postures. Thereafter, the system generates spectral signatures for particular instants in time, correlates these instant signatures with the stored signatures, from which the posture of the body at that instant in time is determined.Type: GrantFiled: December 21, 2005Date of Patent: December 7, 2010Assignee: Cardiac Pacemakers, Inc.Inventors: Loell Boyce Moon, David C Johnson, Veerichetty Kadhiresan, Karen Franke, Brandi Tait
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Patent number: 7844330Abstract: A cardiac rhythm management system includes an implantable device executing a dynamic pacing algorithm after an myocardial infarction (MI) event. The dynamic pacing algorithm dynamically adjusts one or more pacing parameters based on a person's gross physical activity level. Examples of the one or more pacing parameters include atrioventricular pacing delays and pacing channels/sites. The dynamic pacing algorithm provides for improved hemodynamic performance when a person's metabolic need is high, and post MI remodeling control when the person's metabolic need is low.Type: GrantFiled: March 22, 2007Date of Patent: November 30, 2010Assignee: Cardiac Pacemakers, Inc.Inventors: Yinghong Yu, Jiang Ding, Joseph M. Pastore
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Patent number: 7844334Abstract: An implantable medical device includes a dual-use sensor such as a single accelerometer that senses an acceleration signal. A sensor processing circuit processes the acceleration signal to produce an activity level signal and a heart sound signal. The implantable medical device provides for rate responsive pacing in which at least one pacing parameter, such as the pacing interval, is dynamically adjusted based on the physical activity level. The implantable medical device also uses the heart sounds for pacing control purposes or transmits a heart sound signal to an external system for pacing control and/or diagnostic purposes.Type: GrantFiled: July 16, 2007Date of Patent: November 30, 2010Assignee: Cardiac Pacemakers, Inc.Inventors: Keith R. Maile, Krzysztof Z. Siejko
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Patent number: 7844336Abstract: This document discusses, among other things, a system including an implantable medical device. The implantable medical device includes a control circuit and a motion sensing device. The motion sensing device is coupled to the control circuit, and the motion sensing device is configured to transmit signals to the control circuit. The control circuit is configured to identify one or more steps of a patient using the motion sensing device signal.Type: GrantFiled: April 10, 2007Date of Patent: November 30, 2010Assignee: Cardiac Pacemakers, Inc.Inventors: Jilliann G. Fricke, Lemont Baker, Donald L. Hopper, Aaron McCabe, James A. Esler, Chie Kawahara
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Publication number: 20100298898Abstract: An aspect of the present subject matter relates to a system for providing baroreflex stimulation. An embodiment of the system comprises an adverse event detector to sense an adverse event and provide a signal indicative of the adverse event, and a baroreflex stimulator. The stimulator includes a pulse generator to provide a baroreflex stimulation signal adapted to provide a baroreflex therapy, and a modulator to receive the signal indicative of the adverse event and modulate the baroreflex stimulation signal based on the signal indicative of the adverse event to change the baroreflex therapy from a first baroreflex therapy to a second baroreflex therapy. Other aspects are provided herein.Type: ApplicationFiled: August 4, 2010Publication date: November 25, 2010Inventor: Imad Libbus
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Publication number: 20100228308Abstract: Systems including an implantable receiver-stimulator and an implantable controller-transmitter are used for leadless electrical stimulation of body tissues. Cardiac pacing and arrhythmia control is accomplished with one or more implantable receiver-stimulators and an external or implantable controller-transmitter. Systems are implanted by testing external or implantable devices at different tissue sites, observing physiologic and device responses, and selecting sites with preferred performance for implanting the systems. In these systems, a controller-transmitter is activated at a remote tissue location to transmit/deliver acoustic energy through the body to a receiver-stimulator at a target tissue location. The receiver-stimulator converts the acoustic energy to electrical energy for electrical stimulation of the body tissue. The tissue locations(s) can be optimized by moving either or both of the controller-transmitter and the receiver-stimulator to determine the best patient and device responses.Type: ApplicationFiled: September 4, 2009Publication date: September 9, 2010Applicant: EBR Systems, Inc.Inventors: Mark W. Cowan, Debra S. Echt, Richard E. Riley, Axel F. Brisken
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Patent number: 7792581Abstract: Methods and systems for treating patients with diastolic heart failure (DHF) are disclosed which include slowing a patient's heart rate below its intrinsic rate, and controlling the rate using cardiac pacing therapy to improve LV filling and cardiac output. In certain embodiments, a pacing treatment rate may be determined by adjusting an adaptive rate by an amount determined by evaluating one or more patient parameters.Type: GrantFiled: February 28, 2006Date of Patent: September 7, 2010Assignee: Medtronic, Inc.Inventors: Douglas A. Hettrick, Lawrence J. Mulligan, David E. Euler
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Patent number: 7792583Abstract: A medical device delivers a therapy to a patient. Posture events are identified, e.g., a posture of the patient is periodically determined and/or posture transitions by the patient are identified, and each determined posture event is associated with a current therapy parameter set. A value of at least one posture metric is determined for each of a plurality of therapy parameter sets based on the posture events associated with that therapy parameter set. A list of the therapy parameter sets is presented to a user, such as a clinician, for evaluation of the relative efficacy of the therapy parameter sets. The list may be ordered according to the one or more posture metric values to aid in evaluation of the therapy parameter sets. Where values are determined for a plurality of posture metrics, the list may be ordered according to the one of the posture metrics selected by the user.Type: GrantFiled: March 26, 2007Date of Patent: September 7, 2010Assignee: Medtronic, Inc.Inventors: Keith A. Miesel, Kenneth T. Heruth
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Patent number: 7792582Abstract: An active implantable medical device, preferably a device for pacing, resynchronization, defibrillation and/or cardioversion of a patient, that includes functionality that assists in the diagnosis of the patient's clinical status. This devices comprises circuits (10, 12) for measuring one physiologic parameter, preferably minute ventilation (VE), and circuits (14, 16) for measuring a physical parameter, preferably acceleration (G), control logic (18) for discriminating between activity and rest phases of the patient, and analysis circuits (20-28), to process and combine these signals and memorize (store in memory) the obtained results in the form of a data history. The analysis will establish characteristics providing, for successive dates, representative values, for a given period of time, of the physical signal and physiologic signal during activity phases of the patient, and/or of the physiologic signal during rest phases.Type: GrantFiled: November 24, 2006Date of Patent: September 7, 2010Assignee: ELA Medical S.A.S.Inventor: Cyrille Casset
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Patent number: 7783353Abstract: According to an embodiment of a method for providing neural stimulation, activity is sensed, and neural stimulation is automatically controlled based on the sensed activity. An embodiment determines periods of rest and periods of exercise using the sensed activity, and applies neural stimulation during rest and withdrawing neural stimulation during exercise.Type: GrantFiled: November 9, 2006Date of Patent: August 24, 2010Assignee: Cardiac Pacemakers, Inc.Inventors: Imad Libbus, Andrew P. Kramer
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Publication number: 20100185252Abstract: In a device and method for a medical implant for monitoring progression of heart failure in a human heart, an activity sensor provides information related to the activity level of a patient and an oxygen sensor provides information related to the level of oxygen content in venous blood. A determined level of venous oxygen content at a determined activity level is obtained, and that level of venous oxygen content is compared to stored values at a corresponding activity level. The result of the comparison is used as a basis for determining a degree of heart failure.Type: ApplicationFiled: September 27, 2007Publication date: July 22, 2010Inventors: Anders Björling, Malin Öhlander, Tom Eriksson, Johan Eckerdal, Urban Lönn, Kenth Nilsson, Cecilia Tuvstedt, Johan Svahn, Anna-Karin Johansson, Kjell Norén, Michael Broomé
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Patent number: 7761159Abstract: Cardiac devices and methods that select pacing rates for automatic threshold tests based on a patient's hemodynamic need. A sensor-indicated pacing rate corresponding to a patient's hemodynamic need is determined. A test pacing rate is selected from either the sensor-indicated rate or another rate. Capture threshold testing is performed using the selected pacing rate.Type: GrantFiled: March 16, 2005Date of Patent: July 20, 2010Assignee: Cardiac Pacemakers, Inc.Inventors: David William Yost, Clayton Scott Foster
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Patent number: 7756579Abstract: A sensor which can be implanted in a body part to collect data relating to the body part, the sensor includes a jacket which has a side wall which can be deformed inwardly, and first and second ends. A sensor part is contained within the jacket, and fastened to the jacket at or towards the first end of the jacket. The sensor part is at least partially isolated from compressive forces applied to the sensor which cause the side wall of the jacket to deform inwardly.Type: GrantFiled: February 22, 2005Date of Patent: July 13, 2010Assignee: Depuy International Ltd.Inventors: Yaacov Nitzan, Ben-Zion Spector
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Patent number: 7725187Abstract: Provided herein are implantable systems, and methods for use therewith, for estimating a level of noise in a signal produced by an implantable sensor that is sensitive to motion induced noise. Sample data is obtained that is representative of a window of a signal produced by the implantable sensor that is sensitive to motion induced noise. Such sample data includes a plurality of samples each having a magnitude (e.g., amplitude). Each of at least some of the samples is assigned to one of a plurality of bins based on the magnitude of the sample, wherein each bin corresponds to a different range of magnitudes. The plurality of bins includes at least a low bin defining a lowest magnitude range and a high bin defining a highest magnitude range. A level of motion induced noise in the sensor signal is estimated based on a distribution of the samples to the bins.Type: GrantFiled: November 6, 2006Date of Patent: May 25, 2010Assignee: Pacesetter, Inc.Inventors: Yelena Nabutovsky, Taraneh Ghaffari Farazi, Gene A. Bornzin
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Publication number: 20100106212Abstract: In a medical system and a method for operating such a system, the system includes an implantable medical device of a patient, a programmer device, and an extracorporeal stress equipment adapted to exert a physiological stress on the patient, for automatically determining settings of a sensor for sensing a physiological parameter of the patient or for automatically determining a pacing setting of the device over a broad range of workloads of the equipment. The ingoing units and/or devices of the medical system, i.e. the implantable medical device of the patient, the programmer device, and the extracorporeal stress equipment, communicate bi-directionally with each other and form a closed loop.Type: ApplicationFiled: September 25, 2006Publication date: April 29, 2010Inventors: Sven-Erik Hedberg, Patrik Malmberg, Leif Lychou, Jürgen Kerstna
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Publication number: 20100094370Abstract: A method and apparatus for treatment of hypertension and heart failure by increasing secretion of endogenous atrial hormones by pacing of the heart atria. Atrial pacing is done during the ventricular refractory period resulting in premature atrial contraction that does not result in ventricular contraction. Pacing results in the atrial wall stress, peripheral vasodilation, ANP secretion. Concomitant reduction of the heart rate is monitored and controlled as needed with backup pacing.Type: ApplicationFiled: September 8, 2009Publication date: April 15, 2010Applicant: G & L Consulting, LLCInventors: Howard Levin, Mark Gelfand
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Publication number: 20100087887Abstract: Cardioprotective pre-excitation pacing may be applied to stress or de-stress a particular myocardial region delivering of pacing pulses in a manner that causes a dyssynchronous contraction. Such dyssynchronous contractions are responsible for the desired cardioprotective effects of pre-excitation pacing but may also be hazardous. Described herein is a method and system that uses measures of a patient's heart rate or exertion level to control the duty cycles of intermittent pre-excitation pacing.Type: ApplicationFiled: October 5, 2009Publication date: April 8, 2010Inventors: Yanting Dong, Shantha Arcot-Krishnamurthy, Allan C. Shuros, David L. Whitehouse
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Publication number: 20100082078Abstract: Calibration of adaptive-rate pacing by a cardiac rhythm management system using an intrinsic chronotropic response. The cardiac rhythm management system may include an adaptive-rate pacing device. The adaptive-rate pacing device may include an adaptive-rate sensor module for measuring an activity level of the individual. A monitor module may be coupled to the adaptive-rate sensor module, the monitor module monitoring an intrinsic chronotropic response. A calculator module may be coupled to the monitor module, the calculator module calculating a calibrated parameter for the adaptive-rate pacing device based on the intrinsic chronotropic response. An adjuster module may be coupled to the calculator module, wherein the adjuster module adjusts the adaptive-rate pacing device based on the calibrated parameter. The parameters of the adaptive-rate pacing device adjusted by the adjuster module may include a sensor rate target, a maximum sensor rate, and a response factor.Type: ApplicationFiled: September 23, 2009Publication date: April 1, 2010Inventors: Douglas R. Daum, Quan Ni
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Publication number: 20100057157Abstract: A pacemaker with position sensing capability permits built-in monitoring of hemodynamic changes. A miniature position sensor, such as a magnetic coil, is fixed to each implanted pacing lead. The pacemaker housing contains a generator unit, including a magnetic field transmitter. The magnetic field transmitted by the generator unit causes the position sensors to generate position signals, which are returned via the pacing leads to a control unit of the pacemaker. Based on these signals, the control unit senses relative positions of the location sensors, and hence the motion of the leads in the heart. Other location sensing techniques are also disclosed.Type: ApplicationFiled: August 28, 2008Publication date: March 4, 2010Inventors: Assaf Govari, Yitzhack Schwartz
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Patent number: 7672729Abstract: An exemplary method includes delivering stimulation according to one or more stimulation parameters to cause contraction of the diaphragm, monitoring chest activity related to respiration and, in response to the monitoring, adjusting one or more of the one or more stimulation parameters during contraction of the diaphragm and continuing the delivering. Various other exemplary methods, devices, systems, etc., are also disclosed.Type: GrantFiled: January 17, 2007Date of Patent: March 2, 2010Assignee: Pacesetter, Inc.Inventors: Steve Koh, Michael E. Benser
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Patent number: 7672721Abstract: An implantable medical device provides ventricular pacing capabilities and optimizes AV intervals for multiple purposes. In general, intrinsic conduction is promoted by determining when electromechanical systole (EMS) ends and setting an AV interval accordingly. EMS is determined utilizing various data including QT interval, sensor input, and algorithmic calculations.Type: GrantFiled: October 25, 2005Date of Patent: March 2, 2010Assignee: Medtronic, Inc.Inventors: Raul Chirife, William J. Combs, Russell R. Lundstrom
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Patent number: 7672725Abstract: A cardiac rhythm management system modulates the delivery of pacing and/or autonomic neurostimulation pulses based on heart rate variability (HRV). An HRV parameter being a measure of the HRV is produced to indicate a patient's cardiac condition, based on which the delivery of pacing and/or autonomic neurostimulation pulses is started, stopped, adjusted, or optimized. In one embodiment, the HRV parameter is used as a safety check to stop an electrical therapy when it is believed to be potentially harmful to continue the therapy.Type: GrantFiled: January 18, 2005Date of Patent: March 2, 2010Assignee: Cardiac Pacemakers, Inc.Inventors: Joseph M. Pastore, Rodney W. Salo, Gerrard M. Carlson, Andrew P. Kramer, Jiang Ding, Yinghong Yu
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Patent number: 7668590Abstract: A device, such as an implantable cardiac device, and methods for determining exercise diagnostic parameters of a patient are disclosed. Specifically, a maximum observed heart rate of a patient during exercise can be identified when an activity level and a heart rate measurement of the patient exceed predetermined thresholds. Included are methods for filtering out premature heartbeats or noise from the maximum heart rate determination. Methods of determining other exercise parameters, such as workload are also disclosed. The device includes hardware and/or software for performing the described methods.Type: GrantFiled: February 10, 2006Date of Patent: February 23, 2010Assignee: Pacesetter, Inc.Inventor: Michael Paris
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Publication number: 20100042174Abstract: An exemplary method for multi-tier pacing includes delivering single site, left ventricular pacing, sensing patient activity; comparing the sensed patient activity to a patient activity threshold and, if the sensed patient activity exceeds the patient activity threshold, then delivering multi-site, left ventricular pacing for a predetermined period of time and, after the predetermined period of time, delivering single, site left ventricular pacing. In such a method, the period of time may be determined based on cardio-pulmonary demand. Other exemplary technologies are also disclosed.Type: ApplicationFiled: August 12, 2008Publication date: February 18, 2010Applicant: PACESETTER, INC.Inventors: Steve Koh, Michael Yang, Kyungmoo Ryu
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Publication number: 20100036448Abstract: Embodiments of the invention are related to medical systems and methods that can be used to control features of implanted medical devices, amongst other things. In an embodiment, the invention includes a medical system including an external medical device. The external medical device including a video output and a processor in communication with the video output. The system can be configured to display information through the video output as a graph, the graph comprising data representing pacing rates of an implantable device as a function of activity level over time. The system can further be configured to accept user input through direct manipulation of the graph. Other embodiments are also included herein.Type: ApplicationFiled: August 7, 2009Publication date: February 11, 2010Applicant: CARDIAC PACEMAKERS, INCInventors: Jonathan H. Kelly, James Kalgren, David L. Perschbacher, James O. Gilkerson, Les N. Peterson
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Patent number: 7657312Abstract: A method and device for delivering multi-site ventricular pacing therapy in conjunction with parasympathetic stimulation for reducing ventricular wall stress. Such reduction in ventricular wall stress is useful in reversing or preventing the ventricular remodeling which can occur in heart failure patients.Type: GrantFiled: November 3, 2003Date of Patent: February 2, 2010Assignee: Cardiac Pacemakers, Inc.Inventors: Joseph M. Pastore, Zoe Harris-Hajenga, Julio C. Spinelli
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Publication number: 20100016913Abstract: A pacing system delivers cardiac protective pacing therapy (CPPT) to protect the heart from injuries and/or to treat existing injuries. The pacing system receives a set of inputs and delivers optimized cardiac protection pacing tailored for each of different purposes. The system delivers electrical stimulation to provide therapy for angina and/or to provide therapy for co-morbidities related to neural imbalance. In one embodiment, a method for treating angina is provided. A signal is sensed indicative of an incidence of angina and an angina region being a myocardial region affected by the angina. The incidence of angina is detected and the angina region is located. A pacing location is selected remote from the angina region, and CPPT is initiated at the pacing location. The CPPT is adapted to create increased stress at the angina region, to promote mass-redistribution and angiogenesis at the angina region to treat the angina.Type: ApplicationFiled: July 16, 2009Publication date: January 21, 2010Inventors: Shantha Arcot-Krishnamurthy, Allan C. Shuros, Robert Shipley, Jason J. Hamann
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Publication number: 20090312815Abstract: Adaptive rate pacing for improving heart rate kinetics in heart failure patients involves determining onset and sustaining of patient activity. The patient's heart rate response to the sustained activity is evaluated during a time window defined between onset of the activity and a steady-state exercise level. If the patient's heart rate response to the sustained activity is determined to be slow, a pacing therapy is delivered at a rate greater than the patient's intrinsic heart rate based on a profile of the patient's heart rate response to varying workloads. If determined not to be slow, the pacing therapy is withheld. Monitoring-only configurations provide for acquisition and organization of physiological data for heart failure patients. These data can be acquired on a per-patient basis and used to assess the HF status of the patient.Type: ApplicationFiled: August 21, 2009Publication date: December 17, 2009Inventors: Donald L. Hopper, Yinghong Yu, Yanting Dong
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Publication number: 20090306733Abstract: An implantable heart stimulating device for indicating congestive heart failure (CHF) has a processor, an activity sensor that generates an activity signal indicative of a patient's activity, and a blood temperature sensor that measures blood temperature inside the heart of the patient and generates a temperature signal indicative of the measured temperature. From the activity signal and the temperature signal, the processor identifies a characteristic dip in the temperature signal related to a predetermined increase in the activity signal. The processor determines a CHF indicator value indicating the degree of CHF based on the magnitude of the temperature sensor dip for at least two increased activity levels.Type: ApplicationFiled: June 16, 2005Publication date: December 10, 2009Inventor: Anders Bjorling
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Publication number: 20090306734Abstract: Methods and devices for delivering cardiac therapy to a patient are provided. Various implantable device embodiments comprise a plurality of leads and a controller. The leads include at least one lead to be positioned within a lead path to deliver ventricular pacing pulses and to deliver neural stimulation at a site proximate to the heart to inhibit sympathetic nerve activity. The controller controls delivery of the ventricular pacing pulses in accordance with a programmed pacing mode and controls delivery of the neural stimulation. The controller is programmed to deliver remodeling control therapy (RCT) by delivering ventricular pacing to pre-excite a ventricular myocardium region to mechanically unload that region during systole, and further is programmed to deliver anti-remodeling therapy (ART) by delivering neural stimulation to inhibit sympathetic nerve activity in conjunction with RCT. Other embodiments are provided herein.Type: ApplicationFiled: August 19, 2009Publication date: December 10, 2009Inventors: Julia Moffitt, Sophia Wang, Bruce H. Kenknight, Imad Libbus
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Patent number: 7630766Abstract: A method of tuning a cardiac prosthetic pacing device includes (a) monitoring the flow output from the heart, and (b) adjusting the timing of pacing events by the cardiac prosthetic pacing device so as to optimise the flow from the heart under operational conditions.Type: GrantFiled: June 26, 2003Date of Patent: December 8, 2009Assignee: USCOM LimitedInventor: Robert Allan Phillips
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Publication number: 20090287103Abstract: Patient activity and heart rate (HR) are monitored. For each of a plurality of time periods, periods of patient exercise and/or patient activity, if any, are detected based on the monitored patient activity and HR and an activity threshold. A cumulative duration of exercise and/or a cumulative duration of activity is/are determined for each time period, and the peak exercise HR for each period of patient exercise is detected. Information is stored, including duration information indicative of the cumulative duration of exercise and/or the cumulative duration of activity for each time period, and peak exercise information associated with the period of patient exercise during which the highest peak exercise HR occurred for each time period.Type: ApplicationFiled: May 14, 2008Publication date: November 19, 2009Applicant: PACESETTER, INC.Inventor: Ajit Pillai
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Publication number: 20090287270Abstract: A system and method for automatically adjusting the operating parameters of a rate-adaptive cardiac pacemaker. In accordance with the method, maximum exertion levels attained by the patient are measured at periodic intervals and stored. The stored maximum exertion levels may then be used to update a long-term maximal exertion level, and the slope of the rate-response curve is adjusted to map the updated long-term maximal exertion level to a maximum allowable pacing rate. The stored maximum exertion levels may also be used to update a sensor target rate which is used to adjust the slope of the rate response curve.Type: ApplicationFiled: July 22, 2009Publication date: November 19, 2009Inventors: Weimin Sun, Bruce R. Jones, Douglas J. Lang, Donald L. Hopper
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Publication number: 20090281589Abstract: Methods and systems are directed to delivering cardiac pacing therapy to a patient. A pacing therapy associated with one or more pacing parameters is delivered. Alternate cardiac pacing therapies associated with one or more alternate pacing parameters are transitioned to, based on a sleep/wake cycle of the patient. Interactions between the pacing parameters of the pacing therapy and the alternate pacing parameters are resolved. Resolving pacing parameters may be based on analysis of lower rate limits and/or lower rate hysteresis, for example.Type: ApplicationFiled: July 23, 2009Publication date: November 12, 2009Inventors: Jesse W. Hartley, Kent Lee, Quan Ni, Michael A. Querimit, Kenneth L. Baker, Ankur Garg, Kenneth L. Tobacman, Corey J. Miklos
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Patent number: 7610089Abstract: Embodiments include strain sensor devices for detecting movement, morphological changes or other physical parameters within a patient's body tissue. Some embodiments are directed specifically to measuring parameters within a patient's heart and may also be configured to communicate with an implantable stimulation device and associated external programming device.Type: GrantFiled: February 21, 2007Date of Patent: October 27, 2009Assignee: Pacesetter, Inc.Inventors: Rodolfo Rodriguez, Annapurna Karicherla
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Patent number: 7606616Abstract: Calibration of adaptive-rate pacing by a cardiac rhythm management system using an intrinsic chronotropic response. The cardiac rhythm management system may include an adaptive-rate pacing device. The adaptive-rate pacing device may include an adaptive-rate sensor module for measuring an activity level of the individual. A monitor module may be coupled to the adaptive-rate sensor module, the monitor module monitoring an intrinsic chronotropic response. A calculator module may be coupled to the monitor module, the calculator module calculating a calibrated parameter for the adaptive-rate pacing device based on the intrinsic chronotropic response. An adjuster module may be coupled to the calculator module, wherein the adjuster module adjusts the adaptive-rate pacing device based on the calibrated parameter. The parameters of the adaptive-rate pacing device adjusted by the adjuster module may include a sensor rate target, a maximum sensor rate, and a response factor.Type: GrantFiled: March 3, 2006Date of Patent: October 20, 2009Assignee: Cardiac Pacemakers, Inc.Inventors: Douglas R. Daum, Quan Ni
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Publication number: 20090254141Abstract: An apparatus and method for reversing ventricular remodeling with electro-stimulatory therapy. A ventricle is paced by delivering one or more stimulatory pulses in a manner such that a stressed region of the myocardium is pre-excited relative to other regions in order to subject the stressed region to a lessened preload and afterload during systole. The unloading of the stressed myocardium over time effects reversal of undesirable ventricular remodeling.Type: ApplicationFiled: June 15, 2009Publication date: October 8, 2009Inventors: Andrew P. Kramer, Rodney W. Salo, Julio C. Spinelli, Bruce H. KenKnight
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Patent number: 7599741Abstract: Adaptive rate pacing for improving heart rate kinetics in heart failure patients involves determining onset and sustaining of patient activity. The patient's heart rate response to the sustained activity is evaluated during a time window defined between onset of the activity and a steady-state exercise level. If the patient's heart rate response to the sustained activity is determined to be slow, a pacing therapy is delivered at a rate greater than the patient's intrinsic heart rate based on a profile of the patient's heart rate response to varying workloads. If determined not to be slow, the pacing therapy is withheld. Monitoring-only configurations provide for acquisition and organization of physiological data for heart failure patients. These data can be acquired on a per-patient basis and used to assess the HF status of the patient.Type: GrantFiled: June 29, 2006Date of Patent: October 6, 2009Assignee: Cardiac Pacemakers, Inc.Inventors: Donald L. Hopper, Yinghong Yu, Yanting Dong
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Publication number: 20090234401Abstract: This document discusses, among other things, an apparatus comprising an implantable cardiac depolarization sensing circuit, an electrical stimulation circuit, and a pacing mode controller. The pacing mode controller is configured to deliver pacing therapy according to a first pacing mode that is a normal operating mode, and to deliver pacing therapy according to second and third pacing modes. The second and third pacing modes increase mechanical stress on at least a particular portion of the ventricle as compared to the pacing therapy delivered during the first pacing mode. The pacing mode controller alternates between the second and third pacing modes when pacing is changed from the normal operating mode to a stress augmentation mode. The pacing mode controller suspends the change from the normal operating mode to the stress augmentation mode when a condition to prevent the change is detected.Type: ApplicationFiled: March 17, 2009Publication date: September 17, 2009Inventors: John R. Zielinski, Shantha Arcot-Krishnamurthy, Joseph M. Pastore, Jeffrey E. Stahmann, Allan C. Shuros
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Patent number: 7567839Abstract: A system and method for automatically adjusting the operating parameters of a rate-adaptive cardiac pacemaker. In accordance with the method, maximum exertion levels attained by the patient are measured at periodic intervals and stored. The stored maximum exertion levels may then be used to update a long-term maximal exertion level, and the slope of the rate-response curve is adjusted to map the updated long-term maximal exertion level to a maximum allowable pacing rate. The stored maximum exertion levels may also be used to update a sensor target rate which is used to adjust the slope of the rate response curve.Type: GrantFiled: July 13, 2006Date of Patent: July 28, 2009Assignee: Cardiac Pacemakers, Inc.Inventors: Weimin Sun, Bruce R. Jones, Douglas J. Lang, Donald Hopper
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Patent number: 7548785Abstract: An exemplary method includes selecting a cross-correlation frequency having an associated cross-correlation period, detecting and binning a heart rate in a heart rate bin, detecting and binning an activity state in an activity state bin, repeating the detecting and binning a heart rate and the detecting and binning an activity state during a cross-correlation period, and summing the products a bin count of the heart rate bins and a bin count of the activity state bins to provide a cross-correlation index for the cross-correlation period. Other exemplary algorithms, methods, devices, systems, etc., are also disclosed.Type: GrantFiled: June 10, 2004Date of Patent: June 16, 2009Assignee: Pacesetter, Inc.Inventors: Steve Koh, Euljoon Park, Gene A. Bornzin
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Patent number: 7539539Abstract: A method of providing cardiac stimulation therapy and a device for providing the therapy. A patient's cardiac activity as well as cyclical respiration is monitored. Cardiac stimulation is provided as indicated as therapeutic intervention for a variety of cardiac arrhythmias according to variable timing parameters. One or more of the timing parameters under which cardiac pacing stimulations are provided is varied or modulated with the cyclical variations in respiration. The one or more timing parameters are generally shortened or elongated in concert with the alternating inspiration/exhalation phases of respiration. In certain implementations, the patient's respiration is inferred from cardiac based physiologic signals. The methods and devices for providing cardiac stimulation therapy more accurately emulate natural healthy physiologic activity.Type: GrantFiled: October 11, 2005Date of Patent: May 26, 2009Assignee: Pacesetter, Inc.Inventor: Rupinder Bharmi
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Patent number: 7491181Abstract: A device, such as an implantable medical device (IMD) or a programming device, determines when a patient is attempting to sleep. When the device determines that the patient is attempting to sleep, the device determines values for one or more metrics that indicate the quality of a patient's sleep based on at least one physiological parameter of the patient. When the device determines that the patient is not attempting to sleep, the device periodically determines activity levels of the patient. Activity metric values may be determined based on the determined activity levels. A clinician may use sleep quality information and patient activity information presented by a programming device to, for example, evaluate the effectiveness of therapy delivered to the patient by the medical device.Type: GrantFiled: April 15, 2004Date of Patent: February 17, 2009Assignee: Medtronic, Inc.Inventors: Kenneth T. Heruth, Keith A. Miesel
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Patent number: 7493163Abstract: A method and system for automatically adjusting the operating parameters of a rate-adaptive cardiac pacemaker in which maximum exertion levels attained by the patient are measured at periodic intervals and stored in order to compute or update a maximum exercise capacity. The slope of the rate-response curve is then adjusted to map an exertion level corresponding to the updated maximum exercise capacity to a maximum allowable pacing rate. In accordance with the invention, a maximum exercise capacity is determined by cross-checking periodic maximum exertion level sensor values with a motion-level sensor value.Type: GrantFiled: August 1, 2006Date of Patent: February 17, 2009Assignee: Cardiac Pacemakers, Inc.Inventors: Weimin Sun, Bruce R. Jones, Douglas J. Lang
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Patent number: 7471290Abstract: Methods, systems, and apparatus are described for posture detection. Orientations of a body are detected with respect to first and second axes. A movement of the body with respect to a third axis is also detected. Three-dimensional orientations of the body are determined based on the orientations and the movement. The detected posture may be used for applications such as controlling medical devices and detecting patient disorders.Type: GrantFiled: November 18, 2005Date of Patent: December 30, 2008Assignee: Cardiac Pacemakers, Inc.Inventors: Hua Wang, John Hatlestad, Keith R. Maile
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Publication number: 20080306566Abstract: A method for detecting a condition of a heart of a patient using an implantable medical device including the steps of sensing acoustic signals indicative of heart sounds of the heart of the patient; extracting signals corresponding to a first heart sound (S1) and a second heart sound (S2) from sensed signals; calculating an energy value corresponding to a signal corresponding to the first heart sound (S1) and an energy value corresponding to the second heart sound (S2); calculating a relation between the energy value corresponding to the first heart sound and the energy value corresponding to the second heart sound for successive cardiac cycles; and using at least one relation to detect the condition or a change of the condition. A medical device for determining the posture of a patient and a computer readable medium encoded with instructions are used to perform the inventive method.Type: ApplicationFiled: December 16, 2005Publication date: December 11, 2008Inventors: Nils Holmstrom, Kjell Noren
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Publication number: 20080300641Abstract: Embodiments include cardiac information and activity information association systems, apparatus, and methods. An apparatus embodiment includes a cardiac sensor adapted to generate cardiac information descriptive of cardiac functioning of a patient, an activity sensor adapted to generate activity information indicating physical activity of the patient, a processing element adapted to detect a cardiac anomaly based on the cardiac information, an information association element adapted to generate associated cardiac/activity information during the cardiac anomaly, and a data storage apparatus adapted to store the associated cardiac/activity information.Type: ApplicationFiled: June 1, 2007Publication date: December 4, 2008Inventors: Willie N. Brunekreeft, Joanneke G. Groen, Christianus J.J.E. Van Groeningen
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Publication number: 20080294213Abstract: A method for operating an implantable medical device to obtain substantially synchronized closure of the mitral and tricuspid valves based on sensed heart sounds includes sensing an acoustic energy; producing signals indicative of heart sounds of the heart of the patient over predetermined periods of a cardiac cycle during successive cardiac cycles; calculating a pulse width of such a signal; and iteratively controlling a delivery of the ventricular pacing pulses based on calculated pulse widths of successive heart sound signals to identify an RV interval or VV interval that causes a substantially synchronized closure of the mitral and tricuspid valve. A medical device for optimizing an RV interval or VV interval based on sensed heart sounds implements such a method and a computer readable medium encoded with instructions causes a computer to perform such a method.Type: ApplicationFiled: November 30, 2005Publication date: November 27, 2008Inventors: Nils Holmstrom, Kjell Noren