Abstract: An intraocular lens derivation system 10 includes an eye surface measurement device 12 for measuring the shape and position of at least the anterior and a posterior corneal surfaces of the eye, a length measurement device 14 for measuring at least the axial length of the eye, and an IOL calculator 24, connected to devices 12 and 14, for accurately selecting the proper IOL using at least in the selection the measured anterior and posterior corneal surface information and the axial length of the eye.

Abstract: A high refractive index, foldable polymer suitable for use in ophthalmic devices, such as intraocular lenses, is provided. The polymer may be produced from a polymerization reaction of first, second and third monomeric components and a crosslinking agent. The first monomeric component includes an aryl acrylate or an aryl methacrylate. The second monomeric component, which is not an acrylate, includes a monomer having an aromatic ring with a substituent having at least one site of ethylenic unsaturation. The third monomeric component includes a high water content hydrogel-forming monomer. The resulting high refractive index copolymer is durable enough to be cut and polished when dry, and becomes soft and foldable when hydrated.

Abstract: A high refractive index, foldable polymer suitable for use in ophthalmic devices, such as intraocular lenses, is provided. The polymer may be produced from a polymerization reaction of first, second and third monomeric components and a crosslinking agent. The first monomeric component includes an aryl acrylate or an aryl methacrylate. The second monomeric component, which is not an acrylate, includes a monomer having an aromatic ring with a substituent having at least one site of ethylenic unsaturation. The third monomeric component includes a high water content hydrogel-forming monomer. The resulting high refractive index copolymer is durable enough to be cut and polished when dry, and becomes soft and foldable when hydrated.

Abstract: Covalently-bound, hydrophilic copolymer coatings for implants are disclosed. The copolymer coatings comprise 2-phenylethyl (meth)acrylate, a hydrophilic monomer selected from the group consisting of hydroxyalkyl (meth)acrylates and acrylamides, and a reactive plasticizer.

Abstract: An intraocular implant for implantation into the interior of an eye is disclosed. The intraocular implant includes a body member, (the body member has an anterior surface and a posterior surface, and has optical properties,) and, at least one mirror, wherein the at least one mirror is contained within the body member.

Abstract: An eye model system for remotely predicting the in-vivo performance of a vision altering optic includes a representative cornea, a dispersion medium, and a retinal surface. The corneal surfaces provide anatomical shape, optical power, and higher order aberration content. The dispersion medium mimics chromatic dispersion in an actual eye. The retinal surface is moveable to provide selected defocus. A humidity and temperature enclosure may be provided. Model eye elements can be tilted or decentered to simulate actual conditions. An associated method for remotely measuring the performance of a vision altering optic to predict its performance in-vivo includes making topography, wavefront, interferometry, PSF, MTF, or other optical and/or physical measurements of the model eye system with and without the optic in combination.

Abstract: A method of deriving a prediction model and calculating a predicted lens power to provide a desired post-operative spherical equivalent to correct myopia in a phakic eye of a patient using an intraocular lens includes measuring and determining the predictive significance of certain pre-operative characteristics of the eye, including cycloplegic and manifest spherical equivalent, vertex distance, anterior chamber depth, and keratometry. The prediction model is derived using multiple regression analysis on the pre-operative and post operative data. Measured data corresponding to a particular patient is used in the lens power prediction model to calculate the predicted lens power for implantation in the patient.

Abstract: A lens case for a refractive or non-refractive intraocular lens having a support disk for the optic. The case is designed to provide protection and support during washing, sterilization, shipping, and storage. This case has a removable disk that provides a work surface for surgery. Additional features assist in the washing and sterilization of the lens.

Abstract: Apparatus and methods for protecting the edge geometry of an intraocular lens during polishing are disclosed. The apparatus comprises a protective device having a cavity configured to receive the lens and an annular peripheral portion for surrounding and protecting at least one edge corner of the lens. In one embodiment, the peripheral portion has a constant inner diameter and receives the lens in an interference fit. In another embodiment, the lens is trapped between flanges which extend radially inwardly from the peripheral portion. A lens that is encased in the protective device will have a polished central portion and an unpolished peripheral portion after the polishing process has been completed and the protective device has been removed.

Abstract: A two-optic accommodative lens system. The first lens has a negative power and is located posteriorly within the capsular bag and laying against the posterior capsule. The periphery of the first optic contains a pair of generally T-shaped haptics having a generally rectangular slot within the top portion of the “T”. The second optic is located anteriorly to the first optic outside of the capsular bag and is of a positive power. The peripheral edge of the second optic contains a pair of encircling haptics having a notched tab sized and shape to fit within the slots in the haptics on the first optic to lock the second optic onto the first optic. Hinge structures on the encircling haptics allow the second optic to move relative to the first optic along the optical axis of the lens system in reaction to movement of the ciliary muscle.

Abstract: The present invention relates to compositions comprising polysiloxanes suitable for the preparation of accommodating intraocular lenses, having a specific gravity of greater than about 1.0, a refractive index suitable for restoring the refractive power of the natural crystalline lens and a viscosity suitable for injection through a standard cannula. The present invention includes intraocular lenses made from said polysiloxane compositions having a Young's modulus less than about 10 kPa.

Abstract: In a process for treating moulds or mould halves (3) for the production of ophthalmic lenses, in particular contact lenses, the moulds or mould halves (3) are exposed to a plasma at least in the area of their shaping surfaces (310).

Abstract: Disclosed are soft, high refractive index, acrylic materials having an elongation of at least 150%. These materials, especially useful as intraocular lens materials, contain an aryl acrylic hydrophobic monomer as the single principal device-forming monomer. In addition to their use as intraocular lens materials, the present materials are also suitable for use in other ophthalmic or otorhinolaryngological devices, such as contact lenses, keratoprostheses, corneal inlays or rings; otological ventilation tubes and nasal implants.

Abstract: A method of producing intra-ocular lenses or contact lenses including the following steps: a) mechanically forming a lens blank such that it is suitable for correcting an ametropic visual defect, b) measuring the aberration of an eye to be corrected, c) calculating an ablation profile with respect to the lens blank on the basis of the measured aberration, and d) ablating material of the lens blank in accordance with the calculated ablation profile by means of laser radiation.

Abstract: The present invention relates to polymerizable compositions for the manufacture of optical lenses with a high refractive index and a high Abbe number, and optical lenses comprising these compositions.

Abstract: A polymerizable composition that includes a monomer of the formula 1

Abstract: An intraocular lens implant including a telescope body defining an optical path for light to pass therethrough, at least one lens attached to the telescope body, mounting structure connected to the telescope body for mounting the implant in an eye, and an optical blocker disposed in the implant outside of the optical path which minimizes a transmission of light outside the optical path but does not impede transmission of light through the optical path.

Abstract: An intraocular lens for inhibiting posterior capsular opacification, or secondary cataract, includes an optic having a periphery provided with at least two sharp edges which lie radially spaced from each other with respect to the optical axis of the lens optic.

Abstract: An intraocular lens (IOL) insertion apparatus including a cartridge with an IOL-receiving chamber, a handpiece into which the cartridge is loaded, and a plunger rod that extends through a lumen in the cartridge to reliably engage the IOL therein. The chamber is stepped in one section to cause the IOL positioned therein to assume a complex curve. A lip or projection on the plunger rod is aligned with the complex curve and intersects the IOL to reliably engage the IOL across its thickness. The cartridge may be a folding type with a pair of arcuate walls and extension wings joined at a living hinge. The stepped section of the chamber may coincide with the location of the hinge.

Abstract: A method of changing the shape and/or size of an intracorneal ring in situ. The intracorneal ring can be a lens. Preferably, the intracorneal ring is made of a collagen-based polymer material such as COLLAMER.

Abstract: A deformable intraocular lens having frosted and/or colored haptic portions. The frosted haptic portions increase the frictional resistance to movement or rotation within the inner structure of the eye once implanted.

Abstract: Ocular implants composed of homopolymers containing stable elasticity inducing crosslinkers which contain rigid chemical groups disposed between at least two polymerizable ethyleneically unsaturated chemical groups are disclosed. These ocular implants are stable, elastic, soft, optically clear, have high refractive index and low-tack surfaces.

Abstract: Disclosed are soft, high refractive index, acrylic materials having an elongation of at least 150%. These materials, especially useful as intraocular lens materials, contain an aryl acrylic hydrophobic monomer as the single principal device-forming monomer. In addition to their use as intraocular lens materials, the present materials are also suitable for use in other ophthalmic or otorhinolaryngological devices, such as contact lenses, keratoprostheses, corneal inlays or rings; otological ventilation tubes and nasal implants.

Abstract: A method for selecting the size of a phakic intraocular lens positioned in the eye between the iris and the natural lens, is disclosed. In this method, the white-to-white distance of the patient's eye is measured and the length of the lens is based on that measurement. A photographic method of measurement is disclosed.

Abstract: An ophthalmic surgical lens to prevent retinopathy caused by microscopic illumination during cataract or intra-ocular lens surgery. The lens is soft and includes a transparent lens portion placed on a cornea, at least one haptic that extends from the base of the lens portion, and at least one aperture formed by the at least one haptic and the base of the lens portion. The at least one aperture exposes the ocular surface to allow for surgical incisions. The lens portion prevents incisions from being made on the cornea during surgery. The lens also absorbs a patient's corneal refraction so as to prevent the retinopathy.

Abstract: The device comprises a prosthesis designed as a hollow body compressed against the action of restoring spring forces to a cross section reduced relative to an expanded use position, and held in this position by a strippable sheath. After the sheath is stripped, the prosthesis automatically expands to a cross section corresponding to the use position. The sheath, which can be a meshwork in the approximate form of crocheted material, extends over the entire length of the prosthesis and consists of at least one continuous thread and at least one drawstring. The prosthesis, held in the radially compressed position by the sheath, can be mounted displacebly on a feed wire or non-axially-displacebly on the insertion end of a probe or a catheter.

Abstract: The invention is directed to a catheter system having an ultrasonic delivery device, a dilatation balloon, and a stent. The ultrasonic distal head is used to ablate a lesion permitting the dilation balloon to cross the lesion for dilatation and for delivering the stent to the lesion. A catheter body includes a first lumen for dilatation balloon expansion control fluid, and a second lumen for the guide wire. The ultrasonic distal head includes a guide wire aperture large enough to permit complete retraction of the guide wire so that the guide wire may be replaced with another while the catheter remains in place within the vasculature of the patient.

Abstract: There is disclosed an accommodating intraocular lens for implantation in an eye having an optical axis. The lens comprises an anterior portion which in turn comprises an anterior viewing element and an anterior biasing element. The lens further comprises a posterior portion which in turn comprises a posterior viewing element in spaced relationship to the anterior viewing element and a posterior biasing element. The anterior portion and posterior portion meet at first and second apices of the intraocular lens. The anterior portion and the posterior portion and/or the apices are responsive to force thereon to cause the separation between the viewing elements to change. Additional embodiments and methods are also disclosed.

Abstract: A method for determining the propensity of an intraocular lens material to prevent posterior capsule opacification is disclosed. The method involves incubating replicate samples of an IOL material with collagen IV, washing off any loosely bound collagen IV. Following the washing step, one sample is counted to determine the amount of collagen IV that remains adhered to the IOL material. A second sample is further processed prior to counting by subjecting it to a desorption step and a further washing step.

Abstract: The present invention relates to lenses that are capable of post-fabrication power modifications. In general, the inventive lenses comprise (i) a first polymer matrix and (ii) a refraction modulating composition that is capable of stimulus-induced polymerization dispersed therein. When at least a portion of the lens is exposed to an appropriate stimulus, the refraction modulating composition forms a second polymer matrix. The amount and location of the second polymer matrix may modify a lens characteristic such as lens power by changing its refractive index and/or by altering its shape. The inventive lenses have a number of applications in the electronics and medical fields as data storage means and as medical lenses, particularly intraocular lenses, respectively.

Abstract: Biomedical devices, such as ophthalmic lenses, and methods of making such devices having a surface coating including at least one polyionic layer. A preferred method involves spray coating a polycationic material onto a core lens, rinsing and drying the lens, followed by spray coating a polyanionic material, rinsing and drying. The coating process may be applied a plurality of times to achieve a multi-layer coating on the lens surface. A particularly preferred embodiment is a contact lens comprising a highly oxygen permeable hydrophobic core coated with a 5 to 20 bilayers of hydrophilic polyionic materials.

Abstract: An improved intraocular lens (28) is provided which more closely mimics the accommodation and focusing of the eye's natural lens. The lens (28) includes a central optic (30) together with a resilient positioning element (38) including a plurality of spaced-apart positioning legs (44) with openings (46) therebetween. The element (38) is configured so that the equatorial segment (48) thereof is maintained in substantial contact with at least a part of the corresponding equatorial portion (27) of the capsule (20), during essentially all orientations of the lens (28) within the capsule (20). A thin membrane (56) may be used to cover the openings (46) to thereby impede the passage of cells into the lens (28).

Abstract: An intraocular lens made from a class of optically clear, ultraviolet (UV) light absorbing, vulcanized silicone compositions containing about 35 mole % or greater phenyl groups (C6H5), suitable for implanting in the human eye is disclosed. The high mole percentage of phenyl groups in the vulcanized silicone compositions provides a high refractive index (at least about 1.50) and partially blocks ultraviolet light absorption.

Abstract: A surface design method for designing refractive optical devices, and the optical devices themselves, using a wave transform analysis technique to control aberrations and produce a device with more precise refractive properties in response to topographical data derived from the corneal surface. The method can be used to produce other output surfaces.

Abstract: A method of selecting an intraocular lens material for reducing the risk of posterior capsule opacification is disclosed. The method comprises determining the tack of the material.

Abstract: A method of correcting optical aberrations and abnormalities within the optical system of an eye having an intraocular lens implanted therein. The method includes the step of measuring and determining the extent of the aberrations and abnormalities. Removing at least one removable component of the intraocular lens. Modifying at least one surface of the removable component to eliminate or correct the aberrations and abnormalities. Reinserting the modified removable component within the intraocular lens in the optical system through a same wound formed to originally implant the intraocular lens.

Abstract: An improved method of inserting an intraocular lens into an eye comprising removing an existing lens so as to leave a capsular bag intact; at least partially inserting an intraocular lens having at least one haptic incorporating an aperture therein into the capsular bag; and inserting a capsular tension ring into the capsular bag such that the capsular tension ring passes through the aperture is disclosed. A replacement lens arrangement and a sterile packaging therefore are also disclosed.

Abstract: The present invention relates to photocurable siloxane polymers having functional acryl groups, useful in the preparation of intraocular lenses (IOLs). The polymers are siloxane copolymers, wherein the siloxane can be selected from the group consisting of diphenyl siloxane, phenylalkyl siloxane, dialkyl siloxane, and trifluoroalkyl alkyl siloxane. The invention also relates to methods for producing the said siloxane polymers, as well as to producing accommodating lenses in vivo, which means that the tens is formed in the capsular bag of the eye.

Abstract: Collars are disposed on loops of intraocular lenses for improved fixation of loops in rims of capsular bags of eyes. A collar may preferably be positioned on an outer portion of a loop and retained on the loop by an enlarged end portion of the loop.

Abstract: An elliptical accommodative intraocular lens assembly is provided for placement in the evacuated capsular bag of the posterior chamber of an eye after a small incision capsulorhexis, such that as the capsular bag is pulled and released by ciliary muscles, the lenses approach and withdraw from each other to provide focal accommodation.

Abstract: High refractive index copolymers suitable for use in ophthalmic devices are disclosed. The copolymers comprise a) two or more monomers of the structure: wherein: X is H or CH3; m is 0-10; Y is nothing, O, S, or NR wherein R is H, CH3, CnH2n+1(n=1-10), iso-OC3H7, C6H5, or CH2C6H5; Ar is any aromatic ring which can be unsubstituted or substituted with H, CH3, C2H5, n-C3H7, iso-C3H7, OCH3, C6H11, Cl, Br, C6H5, or CH2C6H5; a crosslinking monomer having a plurality of polymerizable ethylenically unsaturated groups, and b) a total of about 5 mole % or less of one or more monomers of the structure: wherein: X is H or CH3; W is —CH3 or (CH2═C(—X)—C(═O)—); and n is such that the weight average molecular weight is approximately 600-1000 if W is —CH3 and approximately 400-1000 if W is (CH2═C(—X)—C(═O)—).

Abstract: Ocular implant of the type comprising an optical portion to which there is connected a haptic portion arranged to position the focal axis of the said optical portion off-center with respect to the geometric axis of the eye, towards the nasal side, provided for insertion into a phakic eye to correct presbyopia, its optical portion having, at least in its central region (7), a multifocal treatment constituting an addition of from +1 to +3.5 dioptres, and its haptic portion (6) ensuring that the focal axis (9) of the optical portion (5) is arranged from 0 to 0.75 mm off-center when the implant is in position in the eye.

Abstract: The present invention relates to methods of implementing an optical element having a refraction modulating composition. The methods include using a wavefront sensor to provide an optical measurement of the optical element. The present invention also relates to systems comprising an optical element having a refraction modulating composition and a wavefront sensor.

Abstract: Optically transparent, high refractive index hydrogels and intraocular lenses fabricated therefrom. The preferred hydrogels have a refractive index of 1.45 or above and a water content of approximately 5 to 30 percent by weight.

Abstract: A method for selecting the size of a phakic intraocular lens positioned in the eye between the iris and the natural lens, is disclosed. In this method, the white to white distance of the patient's eye is measured and the length of the lens is based on that measurement. A photographic method of measurement is disclosed.

Abstract: A surface design method for designing refractive optical devices, and the optical devices themselves, using a wave transform analysis technique to control aberrations and produce a device with more precise refractive properties in response to topographical data derived from the corneal surface. The method can be used to produce other output surfaces.

Abstract: An intraocular lens (38) having focusing capabilities permitting focusing movement of the lens (38) in response to normal ciliary muscle movement incident to changes in the distance between the eye and an object under observation is provided. The lens (38) is designed for surgical implantation within the capsule (22) of an eye (10) and includes an optic (40) and a resilient body (46) which cooperate to form a discoid shaped lens (38) that generally conforms to the shape of the natural capsule (22). When distant objects are viewed, the ciliary body (32) is retracted and the capsule (22) flattens, thus causing the lens (38) to likewise flatten, moving the optic (40) posteriorly, closer to the fovea (26). When viewing near objects, the ciliary body (32) contracts, causing the capsule (22) and thus the lens (38) to expand to their original shape, shifting the optic (40) anteriorly, away from the fovea (26).

Abstract: In apparatus for optical lens forming and displacing, the combination comprises body structure including lens deforming surfaces to receive a lens therebetween and to form the lens into multiple folds; multiple prongs to engage the lens folds; a plunger to displace the prongs endwise of and relative to surfaces and to discharge the folded lens endwise from the structure; and the structure including guide surfaces to cam the prongs toward one another to reduce the lens cross-section being displaced from the structure.

Abstract: A refractive intraocular lens including an optic portion having an outer peripheral edge and two or more but preferably two balanced opposed looped haptic elements. Each looped haptic element is formed to have two broad connecting portions, two radial orientation portions, two spring portions and a linking portion for supporting the optic portion in a patient's eye. The two broad connecting portions of each looped haptic element is permanently connected to the outer peripheral edge of the optic portion. Each looped haptic element is likewise formed to have greater resistance to bending in a plane generally parallel to an eye's optical axis than in a plane generally perpendicular to the eye's optical axis. The intraocular lens is so designed to exhibit less than approximately 1.0 mm axial displacement or tilting of the optic portion along the eye's optical axis under a compression force suitable to effect a 1.0 mm in diameter compression in overall length of the intraocular lens.

Abstract: Collars are disposed on loops of intraocular lenses for improved fixation of loops in rims of capsular bags of eyes. A collar may preferably be positioned on an outer portion of a loop and retained on the loop by an enlarged end portion of the loop.