Quantitative Determination (e.g., Mass, Concentration, Density) Patents (Class 702/23)
  • Patent number: 8761943
    Abstract: A control system for optimizing a chemical loop system includes one or more sensors for measuring one or more parameters in a chemical loop. The sensors are disposed on or in a conduit positioned in the chemical loop. The sensors generate one or more data signals representative of an amount of solids in the conduit. The control system includes a data acquisition system in communication with the sensors and a controller in communication with the data acquisition system. The data acquisition system receives the data signals and the controller generates the control signals. The controller is in communication with one or more valves positioned in the chemical loop. The valves are configured to regulate a flow of the solids through the chemical loop.
    Type: Grant
    Filed: January 27, 2011
    Date of Patent: June 24, 2014
    Assignee: ALSTOM Technology Ltd
    Inventors: Xinsheng Lou, Abhinaya Joshi, Hao Lei
  • Patent number: 8755941
    Abstract: A method and system for controlling a temperature of an exhaust gas being introduced to a catalyst is provided. Using an adjustable flow controller, an adjustable amount of tempering fluid is provided to the exhaust gas prior to the exhaust gas proceeding to the catalyst. A sensor senses a parameter indicative of a temperature of the exhaust gas being introduced to the catalyst. A computer processor uses a relationship to relate the parameter to an adjustment of the adjustable flow controller that will adjust the amount of tempering fluid provided to the exhaust gas and change the temperature of the exhaust gas being introduced to the catalyst toward a target temperature. Adjustment of the adjustable flow controller is initiated by the computer processor to change the flow of the tempering fluid, and the relationship between the parameter and the adjustment of the adjustable flow controller is updated.
    Type: Grant
    Filed: September 2, 2010
    Date of Patent: June 17, 2014
    Assignee: General Electric Company
    Inventors: Larry William Swanson, Douglas Frank Beadie, Neil Colin Widmer, Hua Zhang, Gilbert Otto Kraemer
  • Publication number: 20140156204
    Abstract: Methods to provide glycemic control and therapy management based on monitored glucose data, and current and/or target Hb1AC levels are provided. Systems to provide glycemic control and therapy management based on monitored glucose data, and current and/or target Hb1AC levels are provided. Kits to provide glycemic control and therapy management based on monitored glucose data, and current and/or target Hb1AC levels are provided.
    Type: Application
    Filed: February 6, 2014
    Publication date: June 5, 2014
    Applicant: Abbott Diabetes Care Inc.
    Inventors: Marc Barry Taub, Timothy Christian Dunn, Nathan Christopher Crouther
  • Publication number: 20140156201
    Abstract: A peak assigning apparatus for assigning peaks of a FP configured by peaks and retention time points of the peaks detected from a chromatogram of a multicomponent material includes a peak pattern preparing part preparing a peak pattern for each peak of the target FP and a reference FP that comprises n+1 peaks including n peaks being present on at least one of sides located in front and in the rear of each peak in a time axis direction, and a peak assigning part specifying the peaks corresponding to each other by comparison of the peak patterns.
    Type: Application
    Filed: May 31, 2012
    Publication date: June 5, 2014
    Applicant: TSUMURA & CO.
    Inventors: Yoshikazu Mori, Keiichi Noda, Bunsho Makino
  • Publication number: 20140156202
    Abstract: Analysis system for the quantitative chemical analysis of samples includes a detection equipment to detect the quantity of target analytes in the samples to be analyzed, which includes a chromatography system, an ion source and a mass spectrometer; a data processing system to process quantitative data of the target analytes in the samples analyzed, as detected by the detection equipment; and an innovative database containing corrective and control data and coefficients to calibrate and correct the instrumental response of the detection equipment, wherein the corrective and control data and coefficients are determined and acquired by the database before the actual analysis of the samples, the sample being prepared with a universal dilution solution to minimize the corresponding matrix effect, the data processing system determining the quantitative data of the target analytes by processing the quantitative data taking account of the corrective and control data and coefficients contained in the database.
    Type: Application
    Filed: March 29, 2012
    Publication date: June 5, 2014
    Inventors: Matteo Floridia, Simone Cristoni
  • Publication number: 20140156203
    Abstract: Data of a plurality of samples collected by an LC/MS, GC/MS or other systems are converted into a two-dimensional table format. After LC/MS measurement data on a plurality of samples are obtained and the respective extracted ion chromatograms (XICs) are created, a time-axis adjustment for correcting a discrepancy in the retention time is performed, followed by a process of correcting the missing of data which has occurred in the head and/or tail section of the data as a result of the time-axis adjustment.
    Type: Application
    Filed: June 29, 2011
    Publication date: June 5, 2014
    Applicant: SHIMADZU CORPORATION
    Inventor: Shinichi Yamaguchi
  • Publication number: 20140149050
    Abstract: A data processing system for a chromatograph, in which, when the inflection points in one of the front and rear parts of a peak divided at a peak top cannot be appropriately detected, a tangent to the peak is drawn at the detected inflection point, and an intersection point of the tangent and a baseline is detected. Furthermore, a point at which a perpendicular drawn from the peak top to the baseline intersects with the baseline is also detected. Then, the distance between the intersection points is calculated, and a value obtained by doubling this distance is adopted as a peak width.
    Type: Application
    Filed: June 22, 2012
    Publication date: May 29, 2014
    Applicant: SHIMADZU CORPORATION
    Inventor: Toshinobu Yanagisawa
  • Publication number: 20140142866
    Abstract: Provided are a target FP preparing step, a target FP peak assigning step 149, a target FP peak feature value preparing step, a target FP type-2 preparing step, a target FP area segmentation feature value preparing step, a target FP feature value integrating step, and an evaluating step, to prepare target FP integrated feature values by integrating target FP peak feature values and target FP area segmentation feature values, and to compare and evaluate the target FP integrated feature values and reference FP integrated feature values that correspond to the target FP integrated feature values and are based on a plurality of reference FPs of multicomponent materials as evaluation criteria.
    Type: Application
    Filed: May 31, 2012
    Publication date: May 22, 2014
    Applicant: TSUMURA & CO.
    Inventors: Yoshikazu Mori, Keiichi Noda
  • Publication number: 20140141523
    Abstract: A use composition monitor determines the concentration of peracid and/or peroxide in a use composition using a kinetic assay procedure. A sample mixture containing a sample of the use composition, a diluent and at least one reagent is prepared and analyzed using, for example, an optical detector. A reduced-turbulence optical detector can be used to improve collected response data. A reduced-turbulence optical detector can include a cell body disposed about a length of transparent tubing. The cell body positions one or more emitter/receiver pairs about the transparent tubing. Thus, tube junctions are eliminated and sample flow within the tube is substantially turbulence free.
    Type: Application
    Filed: October 11, 2013
    Publication date: May 22, 2014
    Inventors: Eugene Tokhtuev, Christopher Owen, Anna Pilipchenko, Paul Schilling, Daniel Kamben
  • Publication number: 20140142865
    Abstract: A method of acquiring and interpreting data using a mass spectrometer system and a local mass spectral library comprises: (a) generating a multiplexed mass spectrum, the multiplexed mass spectrum comprising a superposition of a plurality of product-ion mass spectra comprising a plurality of product-ion types, each product-ion mass spectrum corresponding to fragmentation of a respective precursor-ion type; (b) recognizing a respective set of two or more product-ion types corresponding to each of one or more of the product-ion mass spectra by recognizing correlations between the elution profiles of said two or more product-ion types corresponding to each said respective set; and (c) determining if each recognized set of two or more product-ion types corresponds to a product-ion mass spectrum previously observed using said mass spectrometer system by comparing the m/z ratios of the product ion types to information in at least one entry of the local mass spectral library.
    Type: Application
    Filed: November 20, 2012
    Publication date: May 22, 2014
    Inventor: David A. WRIGHT
  • Publication number: 20140140890
    Abstract: The automatic analysis device measures time sequential data on a scattered light amount as reaction process data, and quantitatively determines the concentration of an analyte from a change in light amount. The automatic analysis device has a function of selecting reaction process data to be used for quantitative determination from the reaction process data obtained by measurement using a plurality of light receivers at different angles. As a result of using this function, data is selected from the reaction process data obtained by measurement using the plurality of light receivers at different angles in accordance with the concentration of the analyte and whether the priority is given to high sensitivity in the case where sensitivity is prioritized or a dynamic range, and the result of the quantitative determination is displayed.
    Type: Application
    Filed: May 9, 2012
    Publication date: May 22, 2014
    Applicant: HITACHI HIGH-TECHNOLOGIES CORPORATION
    Inventors: Sakuichiro Adachi, Tomonori Mimura, Hajime Yamazaki, Masaki Shiba
  • Publication number: 20140134653
    Abstract: A method for performing an assay on a liquid sample for the detection of one or more analytes of interest in an assay device having a flow path which includes a sample zone and detection zone thereon includes: dispensing the sample onto the sample zone; combining the sample and a reagent, wherein the sample and reagent may be combined prior to addition of the sample to the sample zone or on the assay device, flowing the combined sample/reagent by capillary action into and through the detection zone having capture elements bound thereto, wherein a signal at least partially representative of the presence or concentration of analyte(s) is produced and detected; determining a reaction time or reaction volume; and determining the concentration of the analyte by using both the detected signal and the reaction time or reaction volume.
    Type: Application
    Filed: November 15, 2013
    Publication date: May 15, 2014
    Inventors: Zhong Ding, Edward R. Scalice
  • Patent number: 8710837
    Abstract: For container-carried explosives or contraband in which the container is made of conductive material and can therefore constitute a Faraday cage, stimulated emissions due to nuclear quadrupole resonance are detected utilizing a terminated balanced transmission line and a directional coupler for the detection of explosives, contraband, narcotics and the like that exist in metal containers.
    Type: Grant
    Filed: December 1, 2010
    Date of Patent: April 29, 2014
    Assignee: BAE Systems Information and Electronic Systems Integration Inc.
    Inventors: Paul A. Zank, John T. Apostolos, Judy Feng
  • Publication number: 20140110574
    Abstract: Methods, apparatus and systems for acquiring spectrometric data from analyte ions implement transient-level data acquisition and peak correction in a time-of-flight mass spectrometer. Transient spectra including analyte peaks and reference mass peaks are recorded, from which a set of averaged peak centroids of the reference masses is generated. The peaks of reference masses in each transient spectrum are compared to the averaged peak centroids. From this comparison, an appropriate correction function is applied to each transient spectrum to correct the positions of the analyte peaks in each transient spectrum. The corrected transient spectra are then summed to obtain a corrected averaged spectrum.
    Type: Application
    Filed: October 19, 2012
    Publication date: April 24, 2014
    Applicant: Agilent Technologies, Inc.
    Inventor: Michael Ugarov
  • Publication number: 20140114586
    Abstract: A method of and apparatus for improving the resolution of compounds eluted from a separation device are disclosed, particularly suited for use in the fields of gas or liquid chromatography.
    Type: Application
    Filed: December 20, 2013
    Publication date: April 24, 2014
    Applicant: Thermo Fisher Scientific (Bremen) GmbH
    Inventor: Hans PFAFF
  • Patent number: 8704166
    Abstract: Provide is an ion trap mass spectrometer which is configured to gain an MS spectrum of only fragment data in an MS/MS analysis, thereby makes it possible to perform the analysis in a short period. For this purpose, the device is comprised of: an ionization unit configured to ionize a sample which has been separated into respective components; an ion trap unit configured to trap ions ionized by ionization unit in an electric field and eject the ions in accordance with the respective masses of the ions; a detection unit configured to detect the ions ejected from the ion trap unit; and a processing unit configured to generate an MS spectrum (mass spectrum) on the basis of data detected in the detection unit. The processing unit further configured to gain an MS spectrum of only fragment data of a target ion from a difference between an MS spectrum gained in an MS analysis made before and/or after an MS/MS analysis and an MS spectrum gained in the MS/MS analysis.
    Type: Grant
    Filed: July 25, 2011
    Date of Patent: April 22, 2014
    Assignee: Hitachi High-Technologies Corporation
    Inventor: Tetsuya Nishida
  • Publication number: 20140100795
    Abstract: Methods for determining a quantitative composition of a multi-component medium comprising at least two known immiscible components comprises determining temperature dependencies of specific heat capacity of each of the components. A sample of the multi-component medium is weighed. Specific heat capacity of the sample is determined at least at i?1 temperature levels, where i is the number of components of the multi-component medium. On the basis of the results from determination of specific heat capacity of the components and the temperature dependencies of specific heat capacity of the components, weight coefficients are calculated for each component of the medium. Quantitative content of each of the components of the multi-component medium is determined on the basis of the obtained values of the weight coefficients of the components.
    Type: Application
    Filed: October 9, 2013
    Publication date: April 10, 2014
    Inventors: ALEXANDER NIKOLAEVICH NADEEV, DMITRY ALEXANDROVICH KOROBKOV, OLEG YURIEVICH DINARIEV, DMITRY EVGENYEVICH MIKLASHEVSKY
  • Publication number: 20140100794
    Abstract: Technologies for increasing sample throughput by predicting the end point response time of a sensor for the analysis of an analyte in a sample are disclosed. In one aspect, a system includes a sensor that generates data signals associated with the measurement of an analyte within the sample. A processor records appropriate data points corresponding to the signals, converts them to a logarithmic function of time scale, and plots the converted data points. The processor then determines a curve that fits the plotted data points and determines a curve fitting equation for the curve. Once the equation is determined, the processor extrapolates an end point response of the sensor using the equation. A value, such as analyte concentration, is then calculated using the extrapolated end point response.
    Type: Application
    Filed: October 2, 2013
    Publication date: April 10, 2014
    Inventors: Sohrab Mansouri, Jose Maria Cervera
  • Publication number: 20140100796
    Abstract: Methods and apparatus for providing data processing and control for use in a medical communication system are provided.
    Type: Application
    Filed: December 13, 2013
    Publication date: April 10, 2014
    Applicant: Abbott Diabetes Care Inc.
    Inventors: Gary Alan Hayter, Geoffrey V. McGarraugh, Kenneth J. Doniger
  • Patent number: 8692991
    Abstract: A method for determining a paint formulation includes: obtaining target color information for a target color, identifying a plurality of toners and corresponding concentrations of the toners in a paint formula that can be used to produce a paint having a color that is similar to the target color, and modifying the paint formula by removing one of the identified toners having a lowest concentration to produce a modified paint formula that can be used to produce a paint having a color that is similar to the target color, and determining if the modified paint formula meets user specified acceptance criteria. An apparatus that can be used to perform the method is also described.
    Type: Grant
    Filed: February 3, 2012
    Date of Patent: April 8, 2014
    Assignee: PPG Industries Ohio, Inc.
    Inventors: Paul Michael Beymore, Jon David Whitby
  • Patent number: 8688389
    Abstract: Absolute quantitation of protein in a sample is provided by comparing a sum or average of the N highest ionization intensities observed for peptides of a particular protein along with a calibration standard. The calibration standard can be in the form of a table generated by prior protein peptide analysis performed using one or more pre-determined proteins. The comparison is used to determine a corresponding absolute quantity of protein based on the observed sum or average of ionization intensities. A simple conversion factor can be applied to the calibration standard value to determine the absolute quantity of protein in the sample.
    Type: Grant
    Filed: August 20, 2012
    Date of Patent: April 1, 2014
    Assignee: Waters Technologies Corporation
    Inventors: Scott Geromanos, Jeffrey Cruz Silva, Hans Vissers, Guo-Zhong Li
  • Publication number: 20140088822
    Abstract: A method of determining payload material density includes a step of determining a capacity volume of a work tool of a machine using an electronic controller of the machine. The work tool is loaded with an initial amount of loaded material matching the capacity volume, and an onboard payload mass calculation algorithm is executed using the electronic controller to determine a mass of the initial amount of loaded material. A density of the initial amount of loaded material is calculated responsive to the mass of the initial amount of loaded material and the capacity volume using the electronic controller. The density of the initial amount of loaded material is stored using the electronic controller, and a productivity datum is calculated responsive to the density of the initial amount of loaded material and a subsequent amount of loaded material.
    Type: Application
    Filed: September 21, 2012
    Publication date: March 27, 2014
    Applicant: CATERPILLAR INC.
    Inventor: Jeffrey Edward Jensen
  • Patent number: 8679851
    Abstract: A method for determining a turbidity point and a free carbohydrate buffer coefficient of an iron-carbohydrate complex. The method includes: (1) contacting the complex with an acid; (2) determining hydrogen ion concentrations and solution turbidities of the complex in acid degradation; and (3) mathematically fitting the data, to obtain the turbidity point of the complex and the free carbohydrate buffer coefficient through mathematical treatment. A method for evaluating the safety of the iron-carbohydrate complex with the turbidity point and the free carbohydrate buffer coefficient.
    Type: Grant
    Filed: January 13, 2010
    Date of Patent: March 25, 2014
    Assignee: Nanjing Lifenergy R&D Co., Ltd
    Inventors: Wen Fang, Chuanzheng Hua, Jie Yang, Guoxin He, Shoujun Xiong
  • Patent number: 8682596
    Abstract: Disclosed is a method for detecting one or both of the native material in an object and any foreign material in the object by parallel-mode spectroscopy, comprising parallel-mode data acquisition, signal processing and data reduction and providing results. Parallel-mode data acquisition comprises producing an interrogating signal simultaneously containing electromagnetic radiation of sufficient bandwidth in the range of approximately 10 GHz to approximately 25 THz to allow simultaneous detection of a plurality of signals at a plurality of frequencies, each signal being at some amplitude, which collectively provide a unique spectral signature of a material whose detection is desired. The signal processing and data reduction comprises processing a signal resulting from exposing the object to the interrogating radiation to produce a three-dimensional data matrix representative of at least any foreign or native material associated with the object.
    Type: Grant
    Filed: February 14, 2011
    Date of Patent: March 25, 2014
    Assignee: Advanced Fusion Systems LLC
    Inventor: Curtis A. Birnbach
  • Patent number: 8682597
    Abstract: A method for determining the composition of a material including the steps of fitting multivariate analytical data of the material to a combination of multivariate analytical data in a database to determine coefficients of the combination so as to determine a reference model of composition based on the coefficients and the compositions in the database, wherein the database includes multivariate analytical data of database materials whose compositions are known, and reconciling the reference model of composition to match properties of the material.
    Type: Grant
    Filed: October 10, 2008
    Date of Patent: March 25, 2014
    Assignee: ExxonMobil Research and Engineering Company
    Inventors: James M. Brown, Anantha Sundaram, Roland B. Saeger, Helen S. Wellons, Clinton R. Kennedy, Stephen B. Jaffe
  • Patent number: 8676513
    Abstract: Methods and devices to detect analyte in body fluid are provided. Embodiments include receiving one or more analyte sensor data, receiving a reference measurement value associated with an analyte level, determining a sensitivity parameter based on the received one or more analyte sensor data and the reference measurement value, performing a probability analysis based on prior analyte sensor data to determine presence of signal attenuation, and generating an output value based on the probability analysis.
    Type: Grant
    Filed: June 21, 2013
    Date of Patent: March 18, 2014
    Assignee: Abbott Diabetes Care Inc.
    Inventors: Kenneth J. Doniger, Erwin Satrya Budiman, Gary Alan Hayter
  • Publication number: 20140067281
    Abstract: The invention allows determining a local change of an admixture concentration in a fluid flow at an entrance to a measurement cell. The change of the admixture concentration in time inside the measurement cell is first determined for a fluid containing the admixture, the change of concentration of which in time at the entrance to the measurement cell is known. Then, an impulse response of the cell is found applying the deconvolution method. The change of the admixture concentration inside the measurement cell is then determined for a fluid being studied with an unknown concentration of the admixture at the entrance. The unknown concentration is determined using the impulse response of the measurement cell and the change of the admixture concentration inside the cell.
    Type: Application
    Filed: August 30, 2013
    Publication date: March 6, 2014
    Applicant: SCHLUMBERGER TECHNOLOGY CORPORATION
    Inventors: EVGENY PIMONOV, ALEXANDER STAROSTIN, OLEG YURIEVICH DINARIEV, DMITRY ALEXANDROVICH KOROBKOV
  • Patent number: 8664590
    Abstract: A method of processing a plurality of image charge/current signals representative of trapped ions undergoing oscillatory motion, e.g. for use in an ion trap mass spectrometer. The method includes producing a linear combination of the plurality of image charge/current signals using a plurality of predetermined coefficients, the predetermined coefficients having been selected so as to suppress at least one harmonic component of the image charge/current signals within the linear combination of the plurality of image charge/current signals.
    Type: Grant
    Filed: March 15, 2013
    Date of Patent: March 4, 2014
    Assignee: Shimadzu Corporation
    Inventors: Li Ding, Ranjan Badheka
  • Patent number: 8666667
    Abstract: Methods and systems are provided for allocating production among reservoir compartments by way of compositional and isotopic analysis. That is, where individual reservoir compartments contribute differing amounts of fluid to a commingled production stream, the methods herein determine the relative contribution of fluid volume from each reservoir compartment. Both a composition-based relative contribution and an isotope-based relative contribution of fluid from each reservoir compartment may be determined to allocate production to each reservoir compartment, the determinations respectively being based on composition mass balances and stable carbon isotope mass balances of components. The combination of both allocation analysis provides quality checks on the results that identify improper allocations that may arise. In addition to production allocation, other applications include, among others, determining the effectiveness of intervention operations and providing feedback for adjusting operations.
    Type: Grant
    Filed: May 18, 2011
    Date of Patent: March 4, 2014
    Assignee: ConocoPhillips Company
    Inventors: Gerald Eric Michael, Olufemi Akande Jokanola
  • Publication number: 20140058684
    Abstract: A dive computer with a free dive mode and/or wireless data transmission capabilities. In one embodiment the invention relates to a diving apparatus including a dive computer having a free dive mode, where the dive computer is configured to calculate a nitrogen loading in the free dive mode using a default value which is the fraction of oxygen in air, and where the free dive mode is used when a diver makes a dive without a self-contained underwater breathing apparatus. Another embodiment includes a method of operating a dive computer including recording two or more first identifiers, receiving pressure information from two or more pressure transmitters, the pressure information comprising second identifiers and pressure measurements, determining whether the pressure information contains one of the two or more first identifiers, and displaying a message indicative of the pressure information that contains one of the two or more first identifiers.
    Type: Application
    Filed: November 1, 2013
    Publication date: February 27, 2014
    Applicant: American Underwater Products, Inc.
    Inventors: Robert Hollis, Michael S. Hollis, Jack Calvin Holman
  • Patent number: 8660803
    Abstract: Nuclear quadrupole resonance measurement using two or more wire loop(s) within a space to define a portal, and driving the wire loop(s) with a baseband digital transmitter generating a chirped or stepped signal, to create a corresponding varying electromagnetic field within the portal. Coherent emissions reflected thereby are detected through a directional coupler feeding the transceiver. The detected coherent emissions are processed with a matched filter to determine presence of a target object within the portal.
    Type: Grant
    Filed: September 27, 2012
    Date of Patent: February 25, 2014
    Assignee: AMI Research & Development, LLC
    Inventors: John T. Apostolos, Judy Feng, William Mouyos, Benjamin McMahon
  • Publication number: 20140052385
    Abstract: A method, computer program and system to identify peaks generated by different physical ions in a solution including substances by analyzing mass and intensity coordinates of all peaks in a set of mass spectra measured with errors for a certain concentration c of the solution is here disclosed. The peaks in different mass spectra are associated to a same ion if they are sufficiently ‘close’ according to specific discrimination criteria that go beyond the proximity of mass values.
    Type: Application
    Filed: October 16, 2013
    Publication date: February 20, 2014
    Applicant: International Business Machines Corporation
    Inventor: Marcello Vitaletti
  • Patent number: 8655601
    Abstract: The present invention relates to a method of detecting soil nutrients or soil nutrients in soil from reflected light, and also includes systems for the measurement, calculation and transmission of data relating to or carrying out that method.
    Type: Grant
    Filed: February 8, 2010
    Date of Patent: February 18, 2014
    Assignee: Bowling Green State University
    Inventors: B. B. Maruthi Sridhar, Robert K. Vincent
  • Patent number: 8645080
    Abstract: A testing method for the bolt to be used under the conditions of excessive wind force by which bolts made of Cr—Mo steel can be separated into a group of bolts usable in cold areas and a group of bolts unusable in cold areas without conducting Charpy impact test involving complicated operation, specifically, a testing method for determining whether bolts made of heat-treated Cr—Mo steel are usable or unusable in cold areas, wherein the determination is conducted on the basis of both J parameter calculated by formula: J=(Si %+Mn %) (P %+Sn %) 104 (wherein P %, Si %, Mn % and Sn % are contents (mass %) of phosphorus (P), silicon (Si), manganese (Mn) and tin (Sn) respectively as disclosed in the inspection certificate of the Cr—Mo steel) and bolt diameter.
    Type: Grant
    Filed: January 9, 2009
    Date of Patent: February 4, 2014
    Assignee: Mitsubishi Heavy Industries, Ltd.
    Inventors: Shin Nakayama, Masuo Tada, Tomohiro Numajiri
  • Publication number: 20140032129
    Abstract: Improved gas leak detection from moving platforms is provided. Automatic horizontal spatial scale analysis can be performed in order to distinguish a leak from background levels of the measured gas. Source identification can be provided by using isotopic ratios and/or chemical tracers to distinguish gas leaks from other sources of the measured gas. Multi-point measurements combined with spatial analysis of the multi-point measurement results can provide leak source distance estimates. These methods can be practiced individually or in any combination.
    Type: Application
    Filed: October 19, 2012
    Publication date: January 30, 2014
    Inventor: Picarro, Inc.
  • Publication number: 20140025313
    Abstract: Methods and sensors for selective fluid sensing are provided. Each sensor includes a resonant inductor-capacitor-resistor (LCR) sensor that is coated with a sensing material. In order to collect data, an impedance spectrum is acquired over a relatively narrow frequency range, such as the resonant frequency range of the LCR circuit. A multivariate signature may be calculated from the acquired spectrum to discern the presence of certain fluids and/or fluid mixtures. The presence of fluids is detected by measuring the changes in dielectric, dimensional, resistance, charge transfer, and other changes in the properties of the materials employed by observing the changes in the resonant electronic properties of the circuit. By using a mathematical procedure, such as principal components analysis (PCA) and others, multiple fluids and mixtures can be detected in the presence of one another, even in a high humidity environment or an environment wherein one or more fluids has a substantially higher concentration (e.g.
    Type: Application
    Filed: September 19, 2013
    Publication date: January 23, 2014
    Applicant: General Electric Company
    Inventors: Radislav Alexandrovich Potyrailo, Cheryl Margaret Surman, Andrew Arthur Paul Burns, Nandini Nagraj
  • Patent number: 8635030
    Abstract: A method is provided for the determination of a NOx concentration value upstream of a Selective Catalytic Reduction (SCR) catalyst in a Diesel engine, the engine having an exhaust line, a Diesel Particulate Filter and a NOx concentration sensor downstream of the SCR catalyst, the method including, but is not limited to estimating the NOx concentration value upstream of the SCR catalyst as a function of at least two engine parameters, measuring the NOx concentration downstream of the SCR catalyst, calculating the difference Z(x, y) between the estimated NOx concentration value and the measured value and, in case the difference is higher than a predetermined threshold, correcting the estimated NOx concentration value with a NOx concentration correction value. The NOx concentration correction value is calculated using a correction map that correlates the at least two engine parameters and the difference Z(x, y) with the NOx concentration correction value.
    Type: Grant
    Filed: June 24, 2011
    Date of Patent: January 21, 2014
    Assignee: GM Global Technology Operations LLC
    Inventors: Igor Zanetti, Davide Mercuri, Marco Petronzi
  • Patent number: 8635024
    Abstract: A sensing device for use in determining at least one attribute of a weather event comprising a plurality of elements. The sensing device can comprise a pressure sensitive surface. The pressure sensitive surface can comprise a pressure sensor. In response to receiving pressure applied by one of the elements, the pressure sensor can generate an output. A first attribute of the at least one attribute of the weather event is determinable at least in part from the output. A system, method, and computer program product for use in determining the at least one attribute are also provided.
    Type: Grant
    Filed: August 2, 2010
    Date of Patent: January 21, 2014
    Assignee: International Business Machines Corporation
    Inventors: David C. Brillhart, Nicholas J. Karels
  • Patent number: 8626342
    Abstract: The present invention comprises devices, systems, methods, and computer program products for managing data related to the dispensing of contrast media as part of a medical procedure. The device and system provide a controller that is capable of communicating with a dispensing device so as to extract, arrange, process, and present a data set (e.g., a usage data set) from the dispensing device to a user such that the user may selectively monitor statistics related to the administration of contrast media, saline, or other consumables used during one or more dispensing operations. The method and computer program product for managing data related to the dispensing of contrast media may further allow for extraction, arrangement, processing, and presentation of the data set via the controller, via a user interface that is operably engaged with the dispensing device and/or via a computer network that may be in communication with the dispensing device.
    Type: Grant
    Filed: October 27, 2005
    Date of Patent: January 7, 2014
    Assignee: Acist Medical Systems, Inc.
    Inventors: Robert C. Williams, Jr., Steven Hartman, Tito Tengco, Clark Godfrey, Alan Cross-Hansen
  • Patent number: 8626451
    Abstract: A method and device allow the determination of the concentrations of a plurality of gas species in a gas mixture based on the output signals from a plurality of gas sensors, each of which is sensitive to a plurality of gas species in the gas mixture. The method includes measuring the response of each sensor at a number of levels of each gas in the mixture, determining a mathematical representation of the response characteristics of each sensor, and using the mathematical representation to determine gas concentrations from sensor readings.
    Type: Grant
    Filed: December 21, 2010
    Date of Patent: January 7, 2014
    Assignee: Delphi Technologies, Inc.
    Inventors: Da Yu Wang, David M. Racine, David D. Cabush
  • Publication number: 20140005954
    Abstract: A method of processing multidimensional data acquired from analytical equipment, which method comprises the steps of providing raw multidimensional data that includes mass spectrometric analytical data obtained from a sample, conducting a first processing step of identifying regions of interest within the raw multidimensional data and conducting a second processing step of refining the raw multidimensional data associated with the one or more regions of interest using peak detection of the mass spectrometric analytical data, wherein the first processing step is conducted using a first processing means and/or a first software program and the second processing step is conducted using a second processing means and/or a second software program, whereby the first and second processing steps are capable of independent implementation.
    Type: Application
    Filed: January 6, 2012
    Publication date: January 2, 2014
    Applicant: MICROMASS UK LIMITED
    Inventors: Keith Richardson, Richard Denny
  • Publication number: 20140005955
    Abstract: A method and apparatus use a first detector (7) sensitive to the interaction of cosmic rays and/or one or more types of particle generated by cosmic rays and a second detector (5a) sensitive to emissions from radioactive material to investigate a volume of material at the investigation location (1). By detecting signals from the first detector (7) during a first measurement period (W) and detecting signals from the first detector and/or second detector during the second measurement period (X), a ratio for their values can be obtained and used to indicate a possibility, wherein the possibility could be the presence of radioactive material associated with the volume of material; or the absence of radioactive material associated with the volume of material; or uncertainty as to whether there is radioactive material associated with the volume of material; or the presence of high atomic number material associated with the volume of material.
    Type: Application
    Filed: December 5, 2011
    Publication date: January 2, 2014
    Applicant: BABCOCK NUCLEAR LIMITED
    Inventor: Mark Wilson
  • Patent number: 8620595
    Abstract: The present disclosure relates to methods for separating or isolating a peptide using reverse phase chromatography. The disclosure also relates to methods for calculating or determining the slope S of a peptide, wherein S is defined according to the Linear-Solvent-Strength equation log k=log k0?S*?. Also provided are a set of peptides with known S values suitable for use in the described methods.
    Type: Grant
    Filed: March 28, 2011
    Date of Patent: December 31, 2013
    Assignee: University of Manitoba
    Inventors: Oleg V. Krokhin, Vic Spicer
  • Patent number: 8615369
    Abstract: A method of and apparatus for improving the resolution of compounds eluted from a separation device are disclosed, particularly suited for use in the fields of gas or liquid chromatography.
    Type: Grant
    Filed: August 25, 2010
    Date of Patent: December 24, 2013
    Assignee: Thermo Fisher Scientific (Bremen) GmbH
    Inventor: Hans Pfaff
  • Publication number: 20130338935
    Abstract: In the case where a peak on a mass spectrum is saturated due to, for example, signal saturation in a detector or an amplifier provided downstream thereof, a data processor performs fitting with a Gaussian function using data included in the rising part and the falling part (range A) of the peak which are not affected by the saturation, to thereby obtain a desired approximate peak shape B. Then, a mass spectrum in which the saturated peak is replaced with the approximate peak thus obtained is created, the mass-to-charge ratio of the peak top is calculated for this mass spectrum, and this mass spectrum is then displayed on a display screen. Moreover, an extracted ion chromatogram is created on the basis of information on mass-to-charge ratio to intensity of this modified mass spectrum and displayed.
    Type: Application
    Filed: May 30, 2013
    Publication date: December 19, 2013
    Inventors: Jun Watanabe, Takashi Sumiyoshi
  • Patent number: 8612163
    Abstract: Methods and apparatus for providing data processing and control for use in a medical communication system are provided.
    Type: Grant
    Filed: August 30, 2012
    Date of Patent: December 17, 2013
    Assignee: Abbott Diabetes Care Inc.
    Inventors: Gary Hayter, Geoffrey V. McGarraugh, Kenneth J. Doniger
  • Patent number: 8612162
    Abstract: A method creates an accurate mass spectrum with a high resolving power based on a plurality of TOF spectra, while reducing the computation to assure real-time processing. TOF spectra are measured when ions are ejected from the loop orbit. Then a coincidence detection method determines what mass-to-charge ratio a peak appearing on the TOF spectra originates from. The time range in which a corresponding peak appears on other TOF spectra is set, and the existence of the peak in that range is determined. When the corresponding peak is found on other TOF spectra, the m/z is deduced from the peak on the TOF spectrum with the highest resolving power and a mass spectrum is created. From the peak density around the peak of interest, the reliability of the deduction is computed. For a low reliability peak, the ion ejection time is optimized and the TOF spectrum is measured again.
    Type: Grant
    Filed: March 14, 2011
    Date of Patent: December 17, 2013
    Assignee: Shimadzu Corporation
    Inventors: Osamu Furuhashi, Kiyoshi Ogawa, Shigeki Kajihara, Tohru Kinugawa
  • Publication number: 20130323771
    Abstract: The present invention relates to analytical methods such as molecular weight determination of polypeptide, in particular Glatiramer acetate. The present invention further relates to an improved process for preparation of polypeptides or pharmaceutically acceptable salts thereof, particularly Glatiramer acetate also known as Copolymer-1. The present invention further relates to characterization of Glatiramer acetate by peptide mapping.
    Type: Application
    Filed: February 14, 2012
    Publication date: December 5, 2013
    Applicant: USV LIMITED
    Inventors: Dhananjay Govind Sathe, Avinash Venkatraman Naidu, Sundaram Subramanian, Anindya Sibnath Bhattacharyya, Rakesh Shekhawat, Divya Lal Saksena, Ramanujam Sukumar, Sanjay Vyankatrao Patil
  • Patent number: 8598513
    Abstract: A mass spectrometer is disclosed wherein a signal output from an ion detector is digitised using an Analogue to Digital Converter. A background or baseline level is dynamically subtracted from the digitised signal whilst the time of flight data is still being acquired. A threshold is also applied dynamically to the digitised signal in order to reduce electronic noise.
    Type: Grant
    Filed: May 14, 2008
    Date of Patent: December 3, 2013
    Assignee: Micromass UK Limited
    Inventors: Anthony James Gilbert, Martin Green
  • Publication number: 20130317756
    Abstract: A method of improving the fidelity of m/z dependent measurements for a species of interest in an analyte in a mass spectrometer, which method comprises the steps of acquiring raw data produced in a mass spectrometer, identifying a region within the raw data that relates to the species of interest, forming a mathematical model to calculate the joint probability distribution of the parameters effecting the m/z dependent measurements, analytically obtaining samples from the joint probability distribution to produce corrected or refined m/z dependent measurements with associated uncertainties.
    Type: Application
    Filed: January 9, 2012
    Publication date: November 28, 2013
    Applicant: MICROMASS UK LIMITED
    Inventors: Keith Richardson, Richard Denny, Martin Green, Jason Lee Wildgoose