Quantitative Determination (e.g., Mass, Concentration, Density) Patents (Class 702/23)
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Patent number: 10448873Abstract: Systems and methods for processing sensor data and self-calibration are provided. In some embodiments, systems and methods are provided which are capable of calibrating a continuous analyte sensor based on an initial sensitivity, and then continuously performing self-calibration without using, or with reduced use of, reference measurements. In certain embodiments, a sensitivity of the analyte sensor is determined by applying an estimative algorithm that is a function of certain parameters. Also described herein are systems and methods for determining a property of an analyte sensor using a stimulus signal. The sensor property can be used to compensate sensor data for sensitivity drift, or determine another property associated with the sensor, such as temperature, sensor membrane damage, moisture ingress in sensor electronics, and scaling factors.Type: GrantFiled: December 1, 2015Date of Patent: October 22, 2019Assignee: DexCom, Inc.Inventors: Sebastian Böhm, Daiting Rong, Peter C. Simpson
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Patent number: 10422781Abstract: A dive computer with a free dive mode and/or wireless data transmission capabilities. In one embodiment the invention relates to a diving apparatus including a dive computer having a free dive mode, where the dive computer is configured to calculate a nitrogen loading in the free dive mode using a default value which is the fraction of oxygen in air, and where the free dive mode is used when a diver makes a dive without a self-contained underwater breathing apparatus. Another embodiment includes a method of operating a dive computer including recording two or more first identifiers, receiving pressure information from two or more pressure transmitters, the pressure information comprising second identifiers and pressure measurements, determining whether the pressure information contains one of the two or more first identifiers, and displaying a message indicative of the pressure information that contains one of the two or more first identifiers.Type: GrantFiled: July 11, 2017Date of Patent: September 24, 2019Assignee: Pelagic Pressure Systems Corp.Inventors: Robert R. Hollis, Michael S. Hollis, Jack Calvin Holman
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Patent number: 10393883Abstract: The subject matter disclosed herein relates to determining a background location of a mobile device using one or more signal metrics.Type: GrantFiled: November 24, 2015Date of Patent: August 27, 2019Assignee: QUALCOMM IncorporatedInventors: Marc Anthony Ische, Ahmad Hatami, Ardalan Heshmati, Zoltan F. Biacs, Douglas Neal Rowitch, Dominic Gerard Farmer, Srigouri Kamarsu, Jie Wu
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Patent number: 10386346Abstract: A data processing system for a chromatograph has an impurity detector including a differential chromatogram creator and a determining section. The differential chromatogram creator calculates a wavelength differential coefficient by differentiating an absorbance spectrum with respect to the wavelength at each point in time of the measurement and creates a differential chromatogram which shows a temporal change in the wavelength differential coefficient. Based on a shape of the thus created differential chromatogram, the determining section determines whether or not a peak of a target component contains an impurity. By this method, whether or not the peak of the target component contains an impurity can be determined with high accuracy, without requiring complex calculations.Type: GrantFiled: August 31, 2012Date of Patent: August 20, 2019Assignee: SHIMADZU CORPORATIONInventors: Yasuhiro Mito, Etsuho Kamata, Hiroshi Miura, Kenichi Mishima, Toshinobu Yanagisawa
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Patent number: 10379234Abstract: A gamma-ray analysis system is described for analyzing gamma-ray emitting radionuclides. The gamma-ray analysis system includes an analytical apparatus having a gamma-ray detector in operative communication with a modular and scalable shield assembly that encases a sample container having a sample to be tested. The detector communicates data to an electronic interface device that converts the data from an analog format to a digital format before a controller transmits the data to a central laboratory for further data processing, analysis and conclusion by qualified laboratory analysts. The controller runs an application software package on a graphic user interface that allows simple steps for conducting testing and data acquisition by the end user, while permitting real time data transmission between the field site and the central location. Functions were implemented for ensuring laboratory quality results while removing knowledge and experience requirements of an end user.Type: GrantFiled: September 8, 2016Date of Patent: August 13, 2019Assignees: THE UNITED STATES OF AMERICA, as represented by the Secretary, Department of Health and Human Services, Mirion Technologies, Inc., Mirion Technologies (Canberra UK) LimitedInventors: Cong Wei, Kelly M. Garnick, Thomas A. Scott, Elon M. Malkin, Jennifer T. Szymanski, Steve Laskos, James Cocks, Jeffrey Raimondi, Richard Mowry, Hiram Gonzalez, Ronald White, Wilhelm Mueller, Robert Fournier
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Patent number: 10319574Abstract: Methods, systems, apparatuses, and/or computer programs. Mass spectrometer test data (e.g. a blood sample of a medical patient) may be associated with metadata information. The associated metadata information may be associated with the medical patient. A subset of a sample reference library may be based on the associated metadata information. The sample reference library may include a plurality of sets of mass spectrometer reference data, in accordance with embodiments. Embodiments match the mass spectrometer test data with mass spectrometer reference data of the selected subset of the sample reference library. Embodiments determine characteristic information of a source of the mass spectrometer test data (e.g. the medical patient) based on the known characteristics of the matched mass spectrometer reference data.Type: GrantFiled: June 30, 2017Date of Patent: June 11, 2019Assignee: Highland Innovations Inc.Inventors: Eung Joon Jo, Yohahn Jo
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Patent number: 10203319Abstract: The invention relates to a process for determining the degree of branching of modified polymers wherein the polymers are modified in the sense that their degree of branching after polymerization was increased once more, wherein the modified polymers are treated with a polar transformation mixture comprising a compound of general formula (I) R1—S—S—R1?? (I) wherein the Mooney viscosity (ML 1+4 at 100° C.) of the polymers is determined before and after the treatment with the polar transformation mixture and the degree of branching is determined.Type: GrantFiled: October 9, 2014Date of Patent: February 12, 2019Assignee: ARLANXEO DEUTSCHLAND GMBHInventors: Heike Kloppenburg, Alicia Le-Sattler
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Patent number: 10203277Abstract: There is provided a technique for automatically determining or predicting a line range specific to a sample that appears in a reaction curve in an automated analyzer for mixing a specimen and a reagent and measuring a change in a mixture of the specimen and the reagent with time. This invention approximates reaction curve data by a function and automatically determines a curve part at an early stage or a second stage of a reaction. The invention determines a line range not including a curve part for each sample and calculates a laboratory test value using absorbance data within the determined line range. This invention also automatically determines a start time of line at the early stage of the reaction on the basis of absorbance data obtained up to a point halfway through the reaction curve, predicts a line range on the basis of the end time of line and a planned end time of line, and calculates a predictive value on the basis of a result of the prediction.Type: GrantFiled: April 5, 2011Date of Patent: February 12, 2019Assignee: HITACHI HIGH-TECHNOLOGIES CORPORATIONInventors: Chihiro Manri, Satoshi Mitsuyama, Tomonori Mimura, Kumiko Kamihara
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Patent number: 10190899Abstract: A thermal flow sensor with improved measurement accuracy is provided. The thermal flow sensor includes: an air flow rate detection element with a diaphragm having a thin-film portion in a semiconductor substrate; at least one heat generating resistor on the diaphragm; at least one temperature measuring resistor that detects temperature on each of an upstream side and a downstream side of the heat generating resistor; and a correction circuit portion that processes an output signal of the air flow rate detection element on the basis of temperature difference information of at least the two temperature measuring resistors on the upstream side and the downstream side, wherein a waveform of the output signal processed by the correction circuit portion is a waveform obtained by cutting a part of a mountain part or a valley part constituting a peak value by outputting of an arbitrary predetermined value when the peak value of the waveform exceeds the arbitrary predetermined value.Type: GrantFiled: February 3, 2014Date of Patent: January 29, 2019Assignee: Hitachi Automotive Systems, Ltd.Inventors: Ryosuke Doi, Shinobu Tashiro, Kazunori Suzuki, Masahiro Matsumoto
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Patent number: 10134008Abstract: Embodiments of the present invention provide systems and methods for evaluating specification data of two or more components. In one embodiment, informational data, including specifications, provides details on these two or more components. The system then derives a set of interactions within these two or more components. From the informational data, in conjunction with interactions within the two or more components, it is determined whether one or more incompatibility issues exist. In instances where one or more incompatibility issues exist, the issue is highlighted and given a description.Type: GrantFiled: September 21, 2015Date of Patent: November 20, 2018Assignee: International Business Machines CorporationInventor: Eric V. Kline
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Patent number: 10060942Abstract: Systems and methods for measuring turbulent gas flux using high-speed vertical wind speed measurements (e.g., on the order of 5-10 Hz or more frequently) and low-speed gas content measurements (e.g., on the order of 5 Hz or less frequently), without the need for the sophisticated and expensive high-speed hardware to separate gas samples (e.g., into accumulation bags) according to updrafts and downdrafts. A time series of high-speed vertical wind speed data is used as a guide to distinguish between updrafts and downdrafts. When vertical wind speed is upward (updraft), the low-speed gas content is recorded into a data structure in one location, or marked with one flag. When vertical wind speed is downward (downdraft), the low-speed gas content is recorded into a different location, or marked with a different flag. Eddy Accumulation or Relaxed Eddy Accumulation computations can be performed using the stored gas content data to determine gas flux.Type: GrantFiled: April 6, 2012Date of Patent: August 28, 2018Assignee: Li-Cor, Inc.Inventors: George G. Burba, Dayle McDermitt, Xiaomao Lin, Liukang Xu, Dave Johnson
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Patent number: 10001462Abstract: A method and system for detecting pesticide residue in agricultural products. The system includes a chromatographic and mass-spectrometric system and a computer. The system inspects first and second sample solutions prepared from two identical extracts of an agricultural product. The first sample solution includes no additives while the second sample is added with a pesticide standard which is intended to be detected by the system for comparison. The computer compares the mass chromatograms of the first and second sample solutions, and calculate an increased integral area by which the peak of the second sample solution in the second mass chromatogram exceeds the peak of the first sample solution in the first mass chromatogram at the same retention time. As such, the concentration of pesticide residue in the sample can be determined by a ratio between the increased integral area and the concentration of the pesticide standard.Type: GrantFiled: March 31, 2017Date of Patent: June 19, 2018Assignee: AGRICULTURAL CHEMICALS AND TOXIC SUBSTANCES RESEARCH INSTITUTE, COUNCIL OF AGRICULTURE, EXECUTIVE YUANInventors: Shao-Kai Lin, Wei-Chen Chuang
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Patent number: 9997341Abstract: A method of mass spectrometry is disclosed comprising experimentally determining or measuring one or more first ion mobility values, collision cross sections or interaction cross sections collision cross sections or first ion mobility parameters and one or more mass or mass to charge ratios of one or more analyte ions, generating a first list of possible candidate compounds which correspond to said one or more analyte ions on the basis of the one or more determined or measured masses or mass to charge ratios, and calculating, estimating or determining one or more second ion mobility values, collision cross sections or interaction cross sections collision cross sections or second ion mobility parameters of at least some of the candidate compounds in the first list.Type: GrantFiled: March 10, 2015Date of Patent: June 12, 2018Assignee: MICROMASS UK LIMITEDInventors: Martin Raymond Green, Kevin Giles, Keith Richardson, Jason Lee Wildgoose
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Patent number: 9989505Abstract: A system includes a gas chromatograph configured to determine experimental chromatographic data including retention times associated with samples. The system also includes a mass spectrometer configured to determine experimental mass spectral data associated with samples. The mass spectrometer can include a quadrupole field ion trap that uses a non-classical detection technique. The system determines a retention index for an unknown sample based upon retention times for a calibration sample and the unknown sample, and identifies reference mass spectral data using the retention index. The reference mass spectral data can include spectra measured using a classical detection technique. The system can compare the experimental mass spectral data to the reference mass spectral data using one or more comparison metrics, such as a percent fragment match and/or a variance match. A score can be determined to identify the unknown sample using one or more of the metrics.Type: GrantFiled: March 14, 2014Date of Patent: June 5, 2018Assignee: SMITHS DETECTION INC.Inventors: Charles S. Sadowski, Greger Andersson, Kevin Judge
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Patent number: 9976997Abstract: When there are a plurality of concentration value candidates, an extreme value of the calibration curve is detected, and the number of calibration points respectively contained in a region having a low concentration and a region having a high concentration is calculated using the extreme value as a boundary. If there is a difference between the numbers of calibration points of both regions, a concentration value candidate present in the region having a larger number of calibration points is selected as a quantitation result. When the numbers of calibration points are the same, the sign of the coefficient of the term of the second degree of the calibration curve is assessed, and a concentration value candidate present in a region in which the relationship between peak area values and concentration values is monotonically increasing is selected as a quantitation result.Type: GrantFiled: October 17, 2016Date of Patent: May 22, 2018Assignee: SHIMADZU CORPORATIONInventor: Kazuma Maeda
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Patent number: 9733227Abstract: A dive computer with a free dive mode and/or wireless data transmission capabilities. In one embodiment the invention relates to a diving apparatus including a dive computer having a free dive mode, where the dive computer is configured to calculate a nitrogen loading in the free dive mode using a default value which is the fraction of oxygen in air, and where the free dive mode is used when a diver makes a dive without a self-contained underwater breathing apparatus. Another embodiment includes a method of operating a dive computer including recording two or more first identifiers, receiving pressure information from two or more pressure transmitters, the pressure information comprising second identifiers and pressure measurements, determining whether the pressure information contains one of the two or more first identifiers, and displaying a message indicative of the pressure information that contains one of the two or more first identifiers.Type: GrantFiled: February 8, 2016Date of Patent: August 15, 2017Assignee: Pelagic Pressure Systems Corp.Inventors: Robert R. Hollis, Michael S. Hollis, Jack Calvin Holman
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Patent number: 9733214Abstract: MRM triggered MRM, where the triggered MRM transitions make use of mobility device parameter values for the same compound, is performed. A plurality of primary MRM transitions are received and stored together with a mobility device parameter value for each transition as an MRM cycle list. Control information instructs a mobility device and a mass spectrometer to interrogate each MRM transition on the MRM cycle list within an MRM cycle of the mass spectrometer. If a product ion intensity value of an MRM transition exceeds a threshold value for a primary MRM transition, a plurality of secondary MRM transitions of the primary MRM transition with different mobility device parameter values are added to the MRM cycle list. The intensities of the measured secondary MRM transitions provide information on the optimum mobility device parameter for each compound.Type: GrantFiled: February 10, 2015Date of Patent: August 15, 2017Assignee: DH Technologies Development Pte. Ltd.Inventors: Christie L. Hunter, David M. Cox
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Patent number: 9464983Abstract: A concentration determination apparatus may determine a concentration of a target component in an arbitrary layer of an observed object including a plurality of light scattering medium layers. The concentration determination apparatus may include an irradiation unit, light scattering medium layer selection unit, a light receiving unit, a light intensity acquisition unit, an optical absorption coefficient calculation unit, and a concentration calculation unit.Type: GrantFiled: July 5, 2011Date of Patent: October 11, 2016Assignees: SEIKO EPSON CORPORATION, NATIONAL UNIVERSITY CORPORATION HOKKAIDO UNIVERSITYInventors: Kazuhiko Amano, Koichi Shimizu
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Patent number: 9431224Abstract: When performing an automatic MS2 analysis on a specimen containing components that include elements whose abundance ratio of stable isotopes is close, to prevent the same component that includes isotopes of differing masses to be successively selected as a precursor ion and allow the MS2 analysis of various components whose retention time to elution is close. As precursor selection conditions, the user is allowed to set in advance the time period for automatic exclusion and a m/z range (?p, q) with respect to any m/z. When the analysis is performed, a precursor selection unit selects a precursor according to a predetermined selection condition for the MS spectrum that was obtained and repeats the MS2 analysis on the precursor ion (m/z=M) for the number of times that is set. Thereafter, for a specified automatic exclusion period, ions falling in a m/z range of M?p to M+q are excluded from selection as a precursor.Type: GrantFiled: April 19, 2011Date of Patent: August 30, 2016Assignee: SHIMADZU CORPORATIONInventor: Shigenobu Nakano
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Patent number: 9399289Abstract: A robot control apparatus, which controls motions of an industrial robot based on processing results of an image processing apparatus which images the robot or objects around the robot, includes: a first communication unit which communicates with a computer for development as an external computer; a second communication unit which is connected to the image processing apparatus via a network; and a command processing unit which opens a communication port of the second communication unit and causes the second communication unit to start communication with the image processing apparatus via a server on the network in response to an open command received by the first communication unit.Type: GrantFiled: September 11, 2012Date of Patent: July 26, 2016Assignee: Seiko Epson CorporationInventor: Nobuyuki Setsuda
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Patent number: 9280516Abstract: The present invention provides a method and system using wireless sensors to validate wired sensors used in applications where the requirements on the reliability of wired sensors are stringent. A computing means periodically collects measurements for each variable from the wired and wireless sensors and compares them against an expected value. The expected value is a weighted average of all the measurements for a variable, in which the weight assigned to the measurement from each sensor is determined according to both its reliability and accuracy. As such, measurements are compared with the corresponding expected value for a particular variable. If the difference between a measurement and its corresponding expected value is found to be unacceptable, the validation computer will generate a corresponding alert. Application examples include 1) validating wired sensors used in safety shutdown systems for industrial facilities and 2) validating wired sensors used to monitor storage tanks.Type: GrantFiled: April 5, 2012Date of Patent: March 8, 2016Assignee: THE UNIVERSITY OF WESTERN ONTARIOInventors: Jin Jiang, Qingfeng Li
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Patent number: 9222873Abstract: An optical device mounted on the interior of an aircraft for distinguishing the morphology of individual atmospheric particles, identifying them as water droplets, ice crystals, dust particles or volcanic ash, including a source of collimated, polarized light and providing this information to the flight crew to assist them in making informed decisions on conditions that might impact aircraft performance.Type: GrantFiled: October 21, 2013Date of Patent: December 29, 2015Assignee: Droplet Measurement Technologies, Inc.Inventors: Darrel Baumgardner, Roy Newton
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Patent number: 9207119Abstract: A spectral feature of a pulsed light beam produced by an optical source is estimated by modifying the wavelength of the pulsed light beam based on a predefined repeating pattern having a pattern period including a plurality of steps, the modification including shifting the wavelength of the pulsed light beam by a wavelength offset from a baseline wavelength for each step in the pattern period; measuring the wavelength of the light beam for each step in the pattern period as the wavelength is modified across the pattern; and estimating a spectral feature of the pulsed light beam over an evaluation window that includes all of the steps within the pattern period based at least in part on the measured wavelength of the light beam for each step in the pattern period.Type: GrantFiled: March 14, 2013Date of Patent: December 8, 2015Assignee: Cymer, LLCInventors: Rostislav Rokitski, Nakgeuon Seong, Kevin O'Brien
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Patent number: 9140677Abstract: In exemplary implementations of this invention, an electronic olfactor determines whether a scent being tested matches the scent of a positive control. The electronic olfactor can perform this scent matching even in a changing olfactory environment, and even if the positive control scent is a combination of hundreds or thousands of different odorants. No prior training is needed, and no attempt is made to identify a single odorant that is unambiguously responsible for a scent. Instead, a computer compares the total scent pattern of a positive control sample with the total scent pattern of a test sample, across a sweep of many permutations of electrical inputs to scent sensors, to try to find any condition under which the total scent patterns do not match. If such a condition cannot be found, then the computer declares a match between the test and target scents.Type: GrantFiled: August 13, 2013Date of Patent: September 22, 2015Assignee: Massachusetts Institute of TechnologyInventors: Andreas Mershin, Asmamaw Wassie, Yael Maguire, David Kong, Shuguang Zhang, Patrick Moran, Karolina Corin
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Patent number: 9112474Abstract: An RC filter that is tunable in terms of its cut-off frequency comprising a drop placed on one or more dielectric layers, a conducting layer underneath the dielectric layer, a nonconducting layer underneath the conducting layer, and an external resistor attached to the drop via an electrode, wherein the cut-off frequency of the filter is tuned by changing the shape or composition of the drop and methods of using the filter as a detector.Type: GrantFiled: August 19, 2011Date of Patent: August 18, 2015Assignee: Board of Regents, The University of Texas SystemInventors: Daniel W. Armstrong, Yasith S. Nanayakkara, Hyejin Moon
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Patent number: 9043162Abstract: A method and apparatus for acquiring data from a mass spectrometer and its transmission to a computer system including a data acquisition engine, a network interface and a throughput optimization module which includes a ring buffer and a protocol stack. A compression engine may be provided between the acquisition engine and the ring buffer. The ring buffer is configured as a number of segments containing portions of memory matching the size of data words from the acquisition engine. When a segment is full of data corresponding to the words, or is partially full and has received data containing an end of scan marker, the number of words in the segment is written into a header word in the segment and the data in that segment are moved to the protocol stack. Subsequent data is received by the next segment in the buffer.Type: GrantFiled: May 28, 2010Date of Patent: May 26, 2015Assignee: Micromass UK LimitedInventors: Peter Gerard Spreadbury, Stephen John Platt
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Patent number: 9037418Abstract: Methods and sensors for selective fluid sensing are provided. Each sensor includes a resonant inductor-capacitor-resistor (LCR) sensor that is coated with a sensing material. In order to collect data, an impedance spectrum is acquired over a relatively narrow frequency range, such as the resonant frequency range of the LCR circuit. A multivariate signature may be calculated from the acquired spectrum to discern the presence of certain fluids and/or fluid mixtures. The presence of fluids is detected by measuring the changes in dielectric, dimensional, resistance, charge transfer, and other changes in the properties of the materials employed by observing the changes in the resonant electronic properties of the circuit. By using a mathematical procedure, such as principal components analysis (PCA) and others, multiple fluids and mixtures can be detected in the presence of one another, even in a high humidity environment or an environment wherein one or more fluids has a substantially higher concentration (e.g.Type: GrantFiled: September 19, 2013Date of Patent: May 19, 2015Assignee: General Electric CompanyInventors: Radislav Alexandrovich Potyrailo, Cheryl Margaret Surman, Andrew Arthur Paul Burns, Nandini Nagraj
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Patent number: 9034594Abstract: A method for verifying carbon storage in seawater to which a growth stimulant has been supplied for stimulating a bloom of nitrogen fixing organisms for enhancing carbon storage therein, comprises selecting a region of seawater including a surface mixed layer, a euphotic zone extending below the surface mixed layer, and a plurality of deeper zones; determining the effect of growth stimulant on the rate of nitrogen fixation and carbon transport in the region; and determining the amount of carbon stored at different depths and projected duration of carbon storage at each of the depths.Type: GrantFiled: April 23, 2008Date of Patent: May 19, 2015Assignee: UNIVERSITY OF SOUTHERN CALIFORNIAInventors: Anthony Michaels, Sergio Sanudo-Wilhelmy, Douglas Capone, James Moffett
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Patent number: 9023651Abstract: The invention relates to a method and a device (100) for determining the amount of a target component (2) in a sample, wherein magnetic particles (2) can bind to a contact surface (4) with kinetics that depend on the sample-amount of the target component. The method comprises at least two washing steps during which magnetic particles (2) are magnetically moved away from the contact surface (4) and corresponding measurements of the remaining amount of magnetic particles (2) at the contact surface (4). The amount of target component in the sample is estimated from at least one of such measurement results. The measurement allows to determine also high concentrations of target component for which the sensor surface (4) is saturated in a steady-state.Type: GrantFiled: October 6, 2009Date of Patent: May 5, 2015Assignee: Koninklijke Philips N.V.Inventors: Toon Hendrik Evers, Wendy Uyen Dittmer
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Patent number: 9020764Abstract: The concept underlying the invention is the development of a generic method for the detection and identification of gases in airplane interior spaces and an associated device, which is small and manageable, has a simple design, and allows the immediate and simultaneous detection and identification of the gases to be examined. This is achieved in that the supply air of the airplane interior space (20) is fed to a measuring device (1) and the measurement results of the measuring device (1) are analyzed by means of mathematical methods. Such methods and the associated devices for the detection and identification of gases in airplane interior spaces are used in order to spot and verify gases, particularly odors and explosive gases and/or gases harmful to people's health.Type: GrantFiled: March 10, 2008Date of Patent: April 28, 2015Assignee: Airsense Analytics GmbHInventors: Andreas Walte, Wolf Münchmeyer, Mario Schmidt
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Patent number: 9014990Abstract: By accurately estimating the survival cell count in a probiotic product, the time for developing the product can be shortened. In a device (1) for estimating survival cell count, a calculation unit (14) calculates an estimated result of the survival cell count nt (CFU/g) of a specific strain contained in a composition after storage, in accordance with the following equation (I). (I) Log10nt=Log10n0?t×EXP{(AT×T+BT)w+(CT×T+DT)}, provided that t stands for the storage period (days)× 1/30, nt stands for the survival cell count (CFU/g) of the strain contained in the composition after the storage period t (days), n0 stands for the viable cell count (CFU/g) of the strain contained in the composition at the initiation of storage, T stands for the storage temperature (° C.), w stands for the water activity value of the composition, AT and CT stand for experimentally determined coefficients specific to the strain, and BT and DT stand for experimentally determined constants specific to the strain.Type: GrantFiled: May 29, 2009Date of Patent: April 21, 2015Assignee: Morinaga Milk Industry Co., Ltd.Inventors: Fumiaki Abe, Ayako Uchijima, Masamichi Muto, Ayako Horigome
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Publication number: 20150106029Abstract: A system and a method are provided for calculating the cetane number, octane number, pour point, cloud point and aniline point of a crude oil fractions from the density and high pressure liquid chromatography (HPLC) of a sample of the crude oil.Type: ApplicationFiled: May 10, 2012Publication date: April 16, 2015Inventors: Omer Refa KOSEOGLU, Adran AL-HAJJI, Saroj Kumar PANDA
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Publication number: 20150106030Abstract: Endotoxin detection systems and corresponding detection methods integrate an optical path detection system based on a conventional laser particle size detector and detect the particle size distribution characteristics of the endotoxin colloidal particles in an aqueous solution by using laser light scattering. One system calculates the concentration of the endotoxin by fitting the correlation of the astigmatism with the concentration of the endotoxin based on scattering intensity of the endotoxin particles at more than three different angles via a quantitative operator.Type: ApplicationFiled: June 13, 2013Publication date: April 16, 2015Applicant: NANJING TUOZHU PHARMACEUTICAL & TECH CO., LTDInventor: Guoping Peng
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Publication number: 20150106028Abstract: A system, method and computer program product are provided for calculating the cetane number, octane number, pour point, cloud point and aniline point of crude oil fractions from the density and Fourier transform ion cyclotron resonance mass spectrometry (FT-ICR MS) of a sample of the crude oil.Type: ApplicationFiled: May 9, 2012Publication date: April 16, 2015Inventors: Omer Refa KOSEOGLU, Adnan Al-Hajji, Hendrik Muller, Hanadi H. Jawad
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Publication number: 20150106027Abstract: A system and a method for applying 13C or 1H NMR spectroscopy to a sample of crude oil in order to calculate the cetane number, pour point, cloud point, aniline point and octane number of a gas oil fraction of the crude oil.Type: ApplicationFiled: February 15, 2012Publication date: April 16, 2015Inventors: Omer Refa Koseoglu, Adnan Al-Hajji, Mohammed Abdullah Al-Ghamdi, Alexander Rebrov
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Publication number: 20150106031Abstract: A system and a method for calculating the cetane number, pour point, cloud point and aniline point of a gas oil fraction of a crude oil from the density and near infrared spectroscopy of a sample of the crude oil.Type: ApplicationFiled: February 15, 2012Publication date: April 16, 2015Inventors: Omer Refa Koseoglu, Adnan Al-Hajji, Anaam Al-Shaikh Ali
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Patent number: 9007073Abstract: Provided are a method of measuring a degree of degradation of a lubricating oil and a measuring device therefor, in which (a) acidity is measured through use of an ISFET of hydrogen ion sensitive type and (b) dielectric constants or electrostatic capacitances at two or more different frequencies are obtained, to thereby determine a degradation state of the lubricating oil based on the acidity and a plurality of values of the dielectric constants or the electrostatic capacitances. Accordingly, the degree of degradation of the lubricating oil can be measured easily and precisely and a degradation mechanism of the lubricating oil can be predicted.Type: GrantFiled: November 22, 2010Date of Patent: April 14, 2015Assignee: Idemitsu Kosan Co., Ltd.Inventor: Tadashi Katafuchi
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Publication number: 20150090872Abstract: A hardware module which operatively carries out a method of compressing mass spectral data, the method comprising: receiving a first signal output from an ion detector of a mass spectrometer; processing the first signal to a digital signal at an output being data frame types representative of the first signal output; temporarily storing the data frame types in a memory block and reading a data frame from the memory block and determining its data frame type and according to its data frame type compressing the data frame according to one or more compression algorithms to generate a compressed data output stream.Type: ApplicationFiled: March 28, 2013Publication date: April 2, 2015Inventors: Stephen John Platt, Keith George Richardson, Darrell Williams, Richard Denny
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Publication number: 20150073726Abstract: The present invention discloses a method of cumulative helium mass spectrometric combination test by using argon gas as gross-leak tracer gas, and specifically gives the procedure for this gross-leak and fine-leak combination test, comprising steps and methods of selecting helium-argon prefilling method or helium-argon pressuring method, fixed or flexible scheme and the criterion RAr0max for argon measured leak rate of gross-leak test according to the rigour grade THemin, cavity volume, leak rate of surficially absorbed helium and argon and the history of the test of a component under test; designing time for pressuring of helium-argon pressuring method, the maximum test-waiting time of fine-leak test and the criterion for helium measured leak rate, helium-argon prefilling and helium-argon pressuring, removing absorbed helium and argon gas, gross-leak test, fine-leak test and complementally testing bigger gross leak, which enhances the sensitivity of gross-leak test, lengthens the maximum test-waiting time ofType: ApplicationFiled: December 19, 2013Publication date: March 12, 2015Inventors: Genglin WANG, Ningbo Li, Fei Li
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Publication number: 20150073725Abstract: In an analyzing system including a commanding unit for sending a command and an executing unit for executing a processing upon receiving the command, a processing instruction may not be executed at the right time due to a heavy traffic of information and other factors. In order to solve this problem, in a preparative separation system 1 according to the present invention, a PC 20 provides the execution time for starting/finishing the fractionation processing to a controller 18. Therefore, even in the case where the time of the PC 20 and that of the controller 18 are not synchronized, the controller 18 can accurately set the execution time for starting/finishing the fractionation in a preparative separation unit 16. A piping 17 may be placed so that the traveling time of sample components is sufficiently larger than the delay time of signals due to the signal transfer lag and other reasons. This can absorb the delay time, allowing the units to cooperate with each other at a correct timing.Type: ApplicationFiled: September 6, 2013Publication date: March 12, 2015Inventors: Keisuke Munetaka, Toshinobu Yanagisawa
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Publication number: 20150073727Abstract: A method of quantifying analytes from mass spectral data, comprising: obtaining a first set of mass spectral data from a first set of analytes eluted from a chromatography column; obtaining a second set of mass spectral data from a second set of analytes eluted from a chromatography column; determining apparent abundances of analytes in each data set; selecting a target analyte and determining localised neighboring analytes by their locality to the target analyte with respect to retention time; determining a locally corrected abundance of the target analyte based on differences between the first and second data sets in the apparent abundance of the localised neighboring analytes; and quantifying the target analyte based on its corrected abundance. A majority of the neighboring analytes are typically substantially unchanged in actual abundance between the first and second data sets and can be used for aligning the abundances between the data sets.Type: ApplicationFiled: March 28, 2013Publication date: March 12, 2015Inventors: Roman Zubarev, Yaroslav Lyutvinskiy
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Publication number: 20150065581Abstract: The present invention relates to methods for the treatment or prevention of fatigue associated with disordered sleep, for example, in multiple sclerosis, fibromyalgia, Fabry's disease, Parkinson's disease, or traumatic brain injury, using cyclobenzaprine. The present invention further relates to a biomarker for the therapeutic effects of a cyclobenzaprine treatment.Type: ApplicationFiled: September 5, 2014Publication date: March 5, 2015Inventors: Seth Lederman, Herb Harris
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Publication number: 20150066387Abstract: MS1 and MS2 measurements of fractionated samples are performed. Based on the identification results and the S/N ratios of the MS1 peaks, an identification probability estimation model showing a relationship between the cumulative number of MS1 peaks and the number of MS1 peaks successfully identified through the MS2 measurements and identifications performed in ascending order of S/N ratio is created. S/N ratios of the MS1 peaks obtained by MS1 measurements are determined, and probabilities of substances in a target sample are estimated from S/N ratios using the aforementioned model. Optimization of precursor-ion selection and data-accumulation number is defined as the problem of maximizing the sum of identification probabilities of MS1 peaks selected for MS2 measurement, and formulated as an objective function using 0-1 variables. This function is solved as a 0-1 integer programming problem under preset conditions.Type: ApplicationFiled: August 28, 2014Publication date: March 5, 2015Applicant: SHIMADZU CORPORATIONInventors: Yoshihiro YAMADA, Shigeki KAJIHARA
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Publication number: 20150066386Abstract: The present disclosure relates to methods and systems for calculating a food additive. A first method includes identifying chemical compounds of an averse food ingredient, identifying chemical compounds of a flavorful food ingredient and calculating a set of chemical compounds for the food additive such that an olfactory perception of a mixture of the averse food ingredient, the flavorful food ingredient and the food additive is the same as an olfactory perception of only the flavorful food ingredient. A first device includes a database storing information identifying chemical compounds of an averse food ingredient and identifying chemical compounds of a flavorful food ingredient, and a processor for calculating a food additive such that an olfactory perception of flavors of a mixture of the averse food ingredient, the flavorful food ingredient and the food additive is the same as an olfactory perception of only the flavorful food ingredient.Type: ApplicationFiled: October 22, 2013Publication date: March 5, 2015Applicant: International Business Machines CorporationInventors: Kush R. Varshney, Lav R. Varshney
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Patent number: 8969791Abstract: In an MS unit, both an intensity of an ion having the highest intensity among the ions originating from a compound as the target of quantitative determination and an intensity of an isotopic ion are measured. A saturation detector determines whether or not digital data produced by an A/D converter from ion-intensity signals have reached a saturation level. A data selection controller selects the ion-intensity data showing the highest intensity when the signal is not saturated or the intensity data of the isotopic ion when the saturation has occurred or is probable to occur. When the latter data is selected, an ion intensity converter converts the intensity data into values corresponding to the intensity data of the highest-intensity ion by multiplying the intensity data by a factor calculated from a known isotopic abundance ratio.Type: GrantFiled: October 28, 2011Date of Patent: March 3, 2015Assignee: Shimadzu CorporationInventor: Kazuo Mukaibatake
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Patent number: 8972198Abstract: Methods of determining analyte concentration. The methods use a fraction of the predicted total charge, from analyte electrolysis, instead of using time, for determination of a data collection endpoint. The total charge is then extrapolated from the data collection endpoint. The analyte concentration is determined from the total charge.Type: GrantFiled: May 11, 2011Date of Patent: March 3, 2015Assignee: Abbott Diabetes Care Inc.Inventors: Ting Chen, Benjamin J. Feldman
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Patent number: 8972203Abstract: By using information collected on-site, estimation of a damage area at that time and also prediction regarding subsequent expansion of a disaster-affected area are performed. The estimation device includes a storage unit that stores an exposure calculation formula expressing an exposure amount, which is an integrated value of the concentration of a material with respect to time, at a certain time and a certain position, by using the diffusivity and flow rate of the material; an information-acquisition unit that acquires position information of disaster victims at a prescribed time as input information; and a calculation unit that obtains a critical value of the exposure amount by applying the position information of each disaster victim at the prescribed time to the exposure calculation formula and that specifies the disaster-affected area at the prescribed time on the basis of the exposure calculation formula for when the critical value is obtained.Type: GrantFiled: August 24, 2010Date of Patent: March 3, 2015Assignee: Mitsubishi Heavy Industries, Ltd.Inventors: Shigehiro Nukatsuka, Akiyoshi Sato, Takeshi Adachi, Kotaro Nariki
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Patent number: 8972196Abstract: Disclosed are embodiments that relate to algorithms and methods for calibrating an analyte sensor, and more particularly, to algorithms for calibrating an optical glucose sensor comprising an equilibrium fluorescent chemical indicator system. In particular, a method of detecting an analyte concentration is disclosed where a modified Michaelis-Menten equation comprising Michaelis-Menten parameters is used to characterize the signal generated by the analyte sensor.Type: GrantFiled: June 4, 2010Date of Patent: March 3, 2015Assignee: Medtronic Minimed, Inc.Inventors: Thomas A. Peyser, Soya Gamsey, Matthew A. Romey, David R. Markle
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Publication number: 20150051843Abstract: A system and method for processing data in chromatographic systems is described. In an implementation, the system and method includes processing data generated by a chromatographic system to generate processed data, analyzing the processed data, and preparing and providing results based on the processed data.Type: ApplicationFiled: September 11, 2012Publication date: February 19, 2015Applicant: LECO CorporationInventors: Jihong Wang, Peter Markel Willis
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Patent number: 8956567Abstract: A control system for optimizing a chemical loop system includes one or more sensors for measuring one or more parameters in a chemical loop. The sensors are disposed on or in a conduit positioned in the chemical loop. The sensors generate one or more data signals representative of an amount of solids in the conduit. The control system includes a data acquisition system in communication with the sensors and a controller in communication with the data acquisition system. The data acquisition system receives the data signals and the controller generates the control signals. The controller is in communication with one or more valves positioned in the chemical loop. The valves are configured to regulate a flow of the solids through the chemical loop.Type: GrantFiled: May 12, 2014Date of Patent: February 17, 2015Assignee: ALSTOM Technology LtdInventors: Xinsheng Lou, Abhinaya Joshi, Hao Lei