Abstract: A speed control device used in an image forming apparatus which includes a detector for checking whether the backing of an image receiving sheet is made of ordinary paper or OHP film, and is capable of controlling the rotating speeds of the motors depending upon the type of the image receiving sheet, i.e., an ordinary paper type or an OHP film type, thereby ensuring that the thermoplastic resin is molten to achieve optimum fluidity irrespective of the type of image receiving sheet.
Abstract: The present invention relates to certain novel 5-substituted pyrimidine nucleosides and pharmaceutically acceptable derivatives thereof and their use in the treatment of varicella zoster virus, cytomegalovirus and Epstein Barr virus infections. Also provided are pharmaceutical formulations and processes for the preparation of the compounds according to the invention.
Abstract: The liquid transfusion apparatus according to the present invention includes a setting device adapted to respectively set a normal level of pressure of the fed liquid and an upper alarm level of pressure of the fed liquid, calculating unit for calculating a percentage of a difference between the detected level of pressure of the liquid and the set normal level to a difference between the set upper alarm level and the set normal level, and display unit for displaying the calculated percentage. The liquid transfusion apparatus is very useful for monitoring the pressure of the liquid which is being administered to a patient.
Type:
Grant
Filed:
November 28, 1989
Date of Patent:
January 7, 1992
Assignee:
Sharp Kabushiki Kaisha
Inventors:
Fumio Miki, Edmund D. D'Silva, Grace M. Esche, Michael S. Fairchild, Larry Kramer, Kenneth M. Lynn
Abstract: A fan device for a refrigerator includes a hollow wall having a front wall portion and a rear wall portion for dividing an interior space of the refrigerator into a heat exchanging zone and a first portion of a storage zone. An air suction opening is formed in the rear wall portion for allowing an air cooled in the heat exchanging zone to be induced into the hollow wall. A fan is disposed in alignment with the air suction opening so as to induce the cooled air. A plurality of forward air outlet slots are formed in the front wall portion for allowing the air in the hollow wall to be blown to the first portion of the storage zone. A rearward air outlet is formed in the rear wall portion for allowing the air in the hollow wall to be blown to a second portion of the storage zone through a duct communicating the rearward air outlet to the second portion.
Abstract: A bolus for releasing a biologically active substance into a liquid environment according to this invention comprising an elongate core, at least one end of which is frustoconical and a liquid impervious casing at one end and open at the other disposed about the core, the bolus being so constructed that, in use, the casing is progressively shed as the core retreats, thereby releasing the active substance at a rate which varies over at least one time period, the casing being so structured as to retain its integrity without disintegrating in the absence of any support provided by the core.
Type:
Grant
Filed:
June 3, 1986
Date of Patent:
December 24, 1991
Assignee:
Coopers Animal Health Limited
Inventors:
Michael T. Shepherd, Rodney C. Baker, Peter H. Marsden
Abstract: This invention relates to certain derivatives of 2', 3'-dideoxycytidine and their use in medical therapy particularly in the treatment of HIV infections. Also provided are pharmaceutical formulations and processes for the manufacture of the compounds according to the invention.
Type:
Grant
Filed:
October 6, 1989
Date of Patent:
December 10, 1991
Assignee:
Burroughs Wellcome Co.
Inventors:
George W. Koszalka, Thomas A. Krenitsky
Abstract: The present invention involves a dual column chromatographic apparatus with column switching capability that is useful in any pressurized fluid chromatography system. The apparatus has at least a first and second chromatographic column, a detector, a fluid conveyance system having a multivalve arrangement, pressurizable fluid conduit assembly, and a controller.The columns are adapted for containing stationary phase or packing for separation of a multicomponent sample into one or more components. The multi-valve arrangement has a plurality of multi-port, multi-modal valves and can include an ingress-egress valve; a guard pre-column valve; detector isolation valve; a set of four, four-port, multi-modal valves; or a set of two four-port, multi-modal valves and one six-port, multi-modal valve or a first valve set and a second valve set. The two chromatographic columns, multi-valve arrangement, and detector are linked for pressurized fluid communication by the pressurized fluid conduit assembly.
Type:
Grant
Filed:
March 23, 1990
Date of Patent:
December 10, 1991
Assignee:
Separations Technology, Inc.
Inventors:
Frederick D. Cazer, Barry L. Scott, Garth E. Strobel
Abstract: 2',3'-Dideoxy-3'-fluoro pyrimidine nucleosides particularly 2',3'-dideoxy-3'-fluorothymidine have been found to have particularly potent activity against adenovirus infections especially those caused by adenoviruses of serotype 8. Such compounds are preferably presented in pharmaceutical formulations adapted for ophthalmic administration.
Type:
Grant
Filed:
August 19, 1988
Date of Patent:
December 3, 1991
Assignee:
Burroughs Wellcome Co.
Inventors:
John W. T. Selway, Lowrie M. Beacham, III, Susan M. Daluge, Joel Van Tuttle, Thomas A. Krenitsky
Abstract: This invention relates to certain 6-substituted 2',3'-dideoxypurine nucleosides and derivatives thereof. The compounds are useful as antivirals.
Type:
Grant
Filed:
October 6, 1989
Date of Patent:
November 26, 1991
Assignee:
Burroughs Wellcome Co.
Inventors:
George W. Koszalka, Charlene L. Burns, Thomas A. Krenitsky, Janet L. Rideout
Abstract: Several novel 3-azido-2,3-dideoxy-.beta.-D-erythro-pentofuranosyl derivatives of substituted pyrimidinones having antiretroviral, especially anti-AIDS, activity are described.
Type:
Grant
Filed:
December 20, 1989
Date of Patent:
November 12, 1991
Assignee:
Burroughs Wellcome Co.
Inventors:
Sammy R. Shaver, George A. Freeman, Janet L. Rideout
Abstract: The present invention relates to certain amino acid esters of the purine nucleoside acyclovir, pharmaceutically acceptable salts thereof and their use in the treatment and prophylaxis of herpes virus infections. The invention also includes pharmaceutical formulations and processes for the preparation of such compounds.
Abstract: A group of 2-aminopurine compounds, which have in the 6-position a hydrogen and in the 9-position an acyclic moiety ##STR1## wherein X is oxygen or sulphur and Y is hydrogen or CH.sub.2 OH (provided than when X is oxygen Y may not be hydrogen), are converted enzymatically in vivo into the corresponding 6-hydroxy (i.e. guanine) derivatives which are potent antiviral compounds. The enzymatic conversion may also be effected ex vivo (i.e. in vitro) as a method of synthesizing the corresponding 6-hydroxy derivatives.
Type:
Grant
Filed:
January 27, 1984
Date of Patent:
October 22, 1991
Assignee:
Burroughs Wellcome Co.
Inventors:
Thomas A. Krenitsky, Lilia M. Beauchamp
Abstract: A vacuum chamber packaging machine for packing goods in bags, comprises a chamber having a lower chamber part and an upper chamber part which is movable relative to the lower chamber part. The bag is hermetically closed by generating a seal joint. Cutting means are provided for severing the bag collar projecting beyond the seal joint. Means for supplying blow air into the chamber and an opening for blowing the severed bag collar out of the chamber are provided for removing the severed bag collar from the chamber.
Abstract: Novel combinations of an antiprotozoal naphthoquinone and a 4-pyridinol or an alkanoic ester thereof wherein the antiprotozoal activity of the combination is potentiated with respect to the corresponding activity of the components of the combination. The combinations are especially useful for the treatment or porphylaxis of malaria.
Type:
Grant
Filed:
December 11, 1989
Date of Patent:
October 1, 1991
Assignee:
Burroughs Wellcome Co.
Inventors:
Victoria S. Latter, Alan T. Hudson, William H. G. Richards, Anthony W. Randall
Abstract: Novel antiprotozoal naphthoquinones having the general formula ##STR1## (wherein either R.sup.1 is hydrogen and R.sup.2 is selected from C.sub.1-6 alkoxy, aralkoxy, C.sub.1-6 alkyl-C.sub.1-6 alkoxy, phenyl substituted by one or two groups selected from halogen and C.sub.1-6 alkyl, halogen and perhalo-C.sub.1-6 alkyl; or R.sup.1 and R.sup.2 are both C.sub.1-6 alkyl or phenyl; and n is 0 or 1) and salt thereof. The compounds of formula (I) are useful for the treatment or prophylaxis of protozoal diseases including malaria, theileriosis and coccidiosis. Various processes for preparing compounds of formula (I) are described.
Abstract: The present invention relates to 6-substituted purine carbocyclic nucleosides and their use in medical therapy particularly in the treatment of HIV and HBV infections. Also provided are pharmaceutical formulations and processes for the preparation of compounds according to the invention.
Abstract: It shall be achieved to design tunnel finishers with air rollers such that the replacement of the jackets of the air rollers is easily possible, even if the air rollers are arranged in the interior of a housing.In order to achieve this object the air roller is supported such that the axis (19) may be removed from one of the two bearings therefore such that the jacket (35) can be replaced via the removed free end.Such tunnel finishers can in particular be used in the clothing industry.