Patents Represented by Attorney Donald Brown
  • Patent number: 5084725
    Abstract: A speed control device used in an image forming apparatus which includes a detector for checking whether the backing of an image receiving sheet is made of ordinary paper or OHP film, and is capable of controlling the rotating speeds of the motors depending upon the type of the image receiving sheet, i.e., an ordinary paper type or an OHP film type, thereby ensuring that the thermoplastic resin is molten to achieve optimum fluidity irrespective of the type of image receiving sheet.
    Type: Grant
    Filed: October 24, 1990
    Date of Patent: January 28, 1992
    Assignee: Sharp Kabushiki Kaisha
    Inventors: Yoshiaki Ibuchi, Koichi Eto
  • Patent number: 5079235
    Abstract: The present invention relates to certain novel 5-substituted pyrimidine nucleosides and pharmaceutically acceptable derivatives thereof and their use in the treatment of varicella zoster virus, cytomegalovirus and Epstein Barr virus infections. Also provided are pharmaceutical formulations and processes for the preparation of the compounds according to the invention.
    Type: Grant
    Filed: January 16, 1990
    Date of Patent: January 7, 1992
    Assignee: Burroughs Wellcome Co.
    Inventors: Dorothy J. M. Purifoy, Saad G. Rahim
  • Patent number: 5078682
    Abstract: The liquid transfusion apparatus according to the present invention includes a setting device adapted to respectively set a normal level of pressure of the fed liquid and an upper alarm level of pressure of the fed liquid, calculating unit for calculating a percentage of a difference between the detected level of pressure of the liquid and the set normal level to a difference between the set upper alarm level and the set normal level, and display unit for displaying the calculated percentage. The liquid transfusion apparatus is very useful for monitoring the pressure of the liquid which is being administered to a patient.
    Type: Grant
    Filed: November 28, 1989
    Date of Patent: January 7, 1992
    Assignee: Sharp Kabushiki Kaisha
    Inventors: Fumio Miki, Edmund D. D'Silva, Grace M. Esche, Michael S. Fairchild, Larry Kramer, Kenneth M. Lynn
  • Patent number: 5076070
    Abstract: A fan device for a refrigerator includes a hollow wall having a front wall portion and a rear wall portion for dividing an interior space of the refrigerator into a heat exchanging zone and a first portion of a storage zone. An air suction opening is formed in the rear wall portion for allowing an air cooled in the heat exchanging zone to be induced into the hollow wall. A fan is disposed in alignment with the air suction opening so as to induce the cooled air. A plurality of forward air outlet slots are formed in the front wall portion for allowing the air in the hollow wall to be blown to the first portion of the storage zone. A rearward air outlet is formed in the rear wall portion for allowing the air in the hollow wall to be blown to a second portion of the storage zone through a duct communicating the rearward air outlet to the second portion.
    Type: Grant
    Filed: March 8, 1990
    Date of Patent: December 31, 1991
    Assignee: Sharp Kabushiki Kaisha
    Inventors: Akira Takushima, Syozo Tanaka, Yoshiharu Shinobu, Masaki Eguchi
  • Patent number: 5075455
    Abstract: The present invention relates to compounds of formula (I)ArCH.sub.2 R.sup.
    Type: Grant
    Filed: August 29, 1989
    Date of Patent: December 24, 1991
    Assignee: Burroughs Wellcome Co.
    Inventor: Kenneth W. Bair
  • Patent number: 5074857
    Abstract: A bolus for releasing a biologically active substance into a liquid environment according to this invention comprising an elongate core, at least one end of which is frustoconical and a liquid impervious casing at one end and open at the other disposed about the core, the bolus being so constructed that, in use, the casing is progressively shed as the core retreats, thereby releasing the active substance at a rate which varies over at least one time period, the casing being so structured as to retain its integrity without disintegrating in the absence of any support provided by the core.
    Type: Grant
    Filed: June 3, 1986
    Date of Patent: December 24, 1991
    Assignee: Coopers Animal Health Limited
    Inventors: Michael T. Shepherd, Rodney C. Baker, Peter H. Marsden
  • Patent number: 5071983
    Abstract: This invention relates to certain derivatives of 2', 3'-dideoxycytidine and their use in medical therapy particularly in the treatment of HIV infections. Also provided are pharmaceutical formulations and processes for the manufacture of the compounds according to the invention.
    Type: Grant
    Filed: October 6, 1989
    Date of Patent: December 10, 1991
    Assignee: Burroughs Wellcome Co.
    Inventors: George W. Koszalka, Thomas A. Krenitsky
  • Patent number: 5071547
    Abstract: The present invention involves a dual column chromatographic apparatus with column switching capability that is useful in any pressurized fluid chromatography system. The apparatus has at least a first and second chromatographic column, a detector, a fluid conveyance system having a multivalve arrangement, pressurizable fluid conduit assembly, and a controller.The columns are adapted for containing stationary phase or packing for separation of a multicomponent sample into one or more components. The multi-valve arrangement has a plurality of multi-port, multi-modal valves and can include an ingress-egress valve; a guard pre-column valve; detector isolation valve; a set of four, four-port, multi-modal valves; or a set of two four-port, multi-modal valves and one six-port, multi-modal valve or a first valve set and a second valve set. The two chromatographic columns, multi-valve arrangement, and detector are linked for pressurized fluid communication by the pressurized fluid conduit assembly.
    Type: Grant
    Filed: March 23, 1990
    Date of Patent: December 10, 1991
    Assignee: Separations Technology, Inc.
    Inventors: Frederick D. Cazer, Barry L. Scott, Garth E. Strobel
  • Patent number: 5070078
    Abstract: 2',3'-Dideoxy-3'-fluoro pyrimidine nucleosides particularly 2',3'-dideoxy-3'-fluorothymidine have been found to have particularly potent activity against adenovirus infections especially those caused by adenoviruses of serotype 8. Such compounds are preferably presented in pharmaceutical formulations adapted for ophthalmic administration.
    Type: Grant
    Filed: August 19, 1988
    Date of Patent: December 3, 1991
    Assignee: Burroughs Wellcome Co.
    Inventors: John W. T. Selway, Lowrie M. Beacham, III, Susan M. Daluge, Joel Van Tuttle, Thomas A. Krenitsky
  • Patent number: 5068320
    Abstract: This invention relates to certain 6-substituted 2',3'-dideoxypurine nucleosides and derivatives thereof. The compounds are useful as antivirals.
    Type: Grant
    Filed: October 6, 1989
    Date of Patent: November 26, 1991
    Assignee: Burroughs Wellcome Co.
    Inventors: George W. Koszalka, Charlene L. Burns, Thomas A. Krenitsky, Janet L. Rideout
  • Patent number: 5064946
    Abstract: Several novel 3-azido-2,3-dideoxy-.beta.-D-erythro-pentofuranosyl derivatives of substituted pyrimidinones having antiretroviral, especially anti-AIDS, activity are described.
    Type: Grant
    Filed: December 20, 1989
    Date of Patent: November 12, 1991
    Assignee: Burroughs Wellcome Co.
    Inventors: Sammy R. Shaver, George A. Freeman, Janet L. Rideout
  • Patent number: 5061708
    Abstract: The present invention relates to certain amino acid esters of the purine nucleoside acyclovir, pharmaceutically acceptable salts thereof and their use in the treatment and prophylaxis of herpes virus infections. The invention also includes pharmaceutical formulations and processes for the preparation of such compounds.
    Type: Grant
    Filed: November 21, 1989
    Date of Patent: October 29, 1991
    Assignee: Burroughs Wellcome Co.
    Inventor: Thomas A. Krenitsky
  • Patent number: 5059604
    Abstract: A group of 2-aminopurine compounds, which have in the 6-position a hydrogen and in the 9-position an acyclic moiety ##STR1## wherein X is oxygen or sulphur and Y is hydrogen or CH.sub.2 OH (provided than when X is oxygen Y may not be hydrogen), are converted enzymatically in vivo into the corresponding 6-hydroxy (i.e. guanine) derivatives which are potent antiviral compounds. The enzymatic conversion may also be effected ex vivo (i.e. in vitro) as a method of synthesizing the corresponding 6-hydroxy derivatives.
    Type: Grant
    Filed: January 27, 1984
    Date of Patent: October 22, 1991
    Assignee: Burroughs Wellcome Co.
    Inventors: Thomas A. Krenitsky, Lilia M. Beauchamp
  • Patent number: 5056292
    Abstract: A vacuum chamber packaging machine for packing goods in bags, comprises a chamber having a lower chamber part and an upper chamber part which is movable relative to the lower chamber part. The bag is hermetically closed by generating a seal joint. Cutting means are provided for severing the bag collar projecting beyond the seal joint. Means for supplying blow air into the chamber and an opening for blowing the severed bag collar out of the chamber are provided for removing the severed bag collar from the chamber.
    Type: Grant
    Filed: May 10, 1990
    Date of Patent: October 15, 1991
    Assignee: Multivac Sepp Haggenmuller KG
    Inventor: Johann Natterer
  • Patent number: 5053418
    Abstract: Novel combinations of an antiprotozoal naphthoquinone and a 4-pyridinol or an alkanoic ester thereof wherein the antiprotozoal activity of the combination is potentiated with respect to the corresponding activity of the components of the combination. The combinations are especially useful for the treatment or porphylaxis of malaria.
    Type: Grant
    Filed: December 11, 1989
    Date of Patent: October 1, 1991
    Assignee: Burroughs Wellcome Co.
    Inventors: Victoria S. Latter, Alan T. Hudson, William H. G. Richards, Anthony W. Randall
  • Patent number: 5053432
    Abstract: Novel antiprotozoal naphthoquinones having the general formula ##STR1## (wherein either R.sup.1 is hydrogen and R.sup.2 is selected from C.sub.1-6 alkoxy, aralkoxy, C.sub.1-6 alkyl-C.sub.1-6 alkoxy, phenyl substituted by one or two groups selected from halogen and C.sub.1-6 alkyl, halogen and perhalo-C.sub.1-6 alkyl; or R.sup.1 and R.sup.2 are both C.sub.1-6 alkyl or phenyl; and n is 0 or 1) and salt thereof. The compounds of formula (I) are useful for the treatment or prophylaxis of protozoal diseases including malaria, theileriosis and coccidiosis. Various processes for preparing compounds of formula (I) are described.
    Type: Grant
    Filed: December 26, 1989
    Date of Patent: October 1, 1991
    Assignee: Burroughs Wellcome Co.
    Inventors: Alan T. Hudson, Anthony W. Randall
  • Patent number: 5049581
    Abstract: The present invention relates to compounds of formula(I) ArCh.sub.
    Type: Grant
    Filed: August 25, 1989
    Date of Patent: September 17, 1991
    Assignee: Burroughs Wellcome Co.
    Inventor: Kenneth W. Bair
  • Patent number: 5049671
    Abstract: The present invention relates to 6-substituted purine carbocyclic nucleosides and their use in medical therapy particularly in the treatment of HIV and HBV infections. Also provided are pharmaceutical formulations and processes for the preparation of compounds according to the invention.
    Type: Grant
    Filed: December 22, 1989
    Date of Patent: September 17, 1991
    Assignee: Burroughs Wellcome Co.
    Inventor: Susan M. Daluge
  • Patent number: 5046335
    Abstract: It shall be achieved to design tunnel finishers with air rollers such that the replacement of the jackets of the air rollers is easily possible, even if the air rollers are arranged in the interior of a housing.In order to achieve this object the air roller is supported such that the axis (19) may be removed from one of the two bearings therefore such that the jacket (35) can be replaced via the removed free end.Such tunnel finishers can in particular be used in the clothing industry.
    Type: Grant
    Filed: February 19, 1991
    Date of Patent: September 10, 1991
    Inventor: Gunther Riba
  • Patent number: D321483
    Type: Grant
    Filed: April 19, 1989
    Date of Patent: November 12, 1991
    Assignee: Integrated Display Technology Ltd.
    Inventor: Raymond Chan