Abstract: A launcher for a soft compressible closed cell foam ball which includes a cavity in which the ball is forced into from the front of the barrel and is held loosely therein and a plunger coupled to the barrel for causing theball to be compressed and then spring out of the cavity accompanied by a loud popping sound.
Abstract: A ball launcher for launching a plurality of soft closed cell plastic compressible balls, one ball at a time, by causing a plurality of balls in a line, one ball at a time (each time the plunger is moved back and forth), to squeeze past a constriction at the front of the launcher. The front most ball in the line of balls, to be launched, is urged against the constriction by a resilient biasing carriage engaging the rear most ball in the line of balls.
Abstract: An appliance support as used in particular in intensive care stations of hospitals comprises a support arm for receiving support members for the appliances and supply connections for operating the same. Such an appliance support shall be modified to allow as many appliances, such as pumps and the like, as possible to be mounted thereto and to be movable relative thereto. To this end the support arm comprises a longitudinally extending groove and a support member being slidable in the groove and being pivotable around an axis relative to the support arm.
Abstract: A packaging machine for producing a reclosable package from a bottom film, a top film and a closure strip therebetween shall be designed to facilitate the generation of a hermetic seal in particular in the region of the closure strip with low film consumption. To this end a sealing station for sealing an edge portion between the product and the closure strip and an evacuation and sealing station having a chamber for sealing the package including the edge portion are provided.
Abstract: Novel (2S, 3S, 5R) morpholinols of formula (I) ##STR1## together with the (+-)-(2R*,3R*,5S*) racemates thereof, and their salts, whereinX is hydrogen, alkyl of 1 to 6 carbon atoms, cycloalkyl of 3 to 6 carbon atoms or a group --CH.sub.2 --X.sup.1 where X.sup.1 is cycloalkyl of 3 to 6 carbon atoms.The compounds have a variety of uses in human medicine, in particular in the treatment of mental disorders such as depression.
Type:
Grant
Filed:
April 2, 1991
Date of Patent:
April 14, 1992
Assignee:
Burroughs Wellcome Co.
Inventors:
James L. Kelley, David L. Musso, Grady E. Boswell, Barrett R. Cooper
Abstract: The present invention relates to electrophoresis. More particularly, the present invention relates to utilization of electrophoresis with controlled cooling. Still more particularly, the invention relates to a method and apparatus for separating chemical components in a solution in both a batch and a continuous mode.
Abstract: A class of halogen-substituted diphenylsulfide compounds are disclosed which produce a large selective inhibition of serotonin uptake in brain. Such compounds are useful in the treatment of depression, anxiety, obsessive compulsive disorders and substance abuse disorders such as alcoholism.
Type:
Grant
Filed:
June 28, 1991
Date of Patent:
April 14, 1992
Assignee:
Burroughs Wellcome Co.
Inventors:
Lawrence E. Brieaddy, Claudia E. B. Hollingsworth, Barrett R. Cooper
Abstract: A method of cleaning a photosensitive member in an electrophotographic apparatus in which an electrophotographic operation is performed by charging the photosensitive member with a predetermined voltage, exposing the charged photosensitive member so as to form a latent image thereon and developing the latent image by use of toner, includes the steps of charging the photosensitive member with a half tone level voltage which is smaller than the predetermined voltage, and developing the charged photosensitive member by use of toner without exposing the charged photosensitive member, so as to form a uniform half tone toner image thereon. The cleaning method also includes the step of scraping off the toner of the uniform half tone toner image from the photosensitive member by a blade abutting thereto.
Abstract: The present invention is concerned with compounds of formula (I) ##STR1## wherein R.sub.1 is hydrogen;R.sub.2 is carbonyl; andR.sub.3 is hydroxy;and salts thereof, with processes for preparing same and with their use in medicine for the treatment of hypertension.
Type:
Grant
Filed:
December 18, 1989
Date of Patent:
April 7, 1992
Assignee:
Burroughs Wellcome Co.
Inventors:
John D. McDermed, Anjaneyulu S. Tadepalli, Vincent H. Chang, Kevin P. Hurley
Abstract: A method of controlling veterinary ectoparasites of mammals and birds of the sub-orders Ixodoidea and Sarcoptiformes comprising the application of a parasiticidally effective, non-toxic amount of a pyrethroid of formula ##STR1## together with at least one parasiticidal organophosphorus compound active against said ectoparasites.
Abstract: A halogen-substituted diphenylsulfide compound is disclosed which produce a large selective inhibition of serotonin uptake in brain. This compound is useful in the treatment of depression as well as anxiety, obsessive compulsive disorders and alcoholism.
Abstract: Treatment of AIDS or humans carrying or infected with the AIDS virus or having antibodies to the AIDS virus is disclosed using the compound 3'-azido-3'-deoxythymidine or a pharmaceutically acceptable basic salt thereof.Also disclosed is the use of the 5'-mono-, di- and triphosphate of 3'-azido-3'-deoxythymidine or a pharmaceutically acceptable basic salt thereof for the same purpose.
Type:
Grant
Filed:
November 30, 1990
Date of Patent:
March 3, 1992
Assignee:
Burroughs Wellcome Co.
Inventors:
Janet L. Rideout, David W. Barry, Sandra N. Lehrmaan, Martha H. St. Clair, Phillip A. Furman
Abstract: The invention relates to a correction and supporting apparatus. Such an apparatus is in particular used for stabilizing an injured spinal column. For allowing an easy adjustment of the vertebrae to be stabilized and a later readjustment four screws are provided each having a threaded shaft portion 7 and a receiver member 8 joined thereto. A first pair of threaded rods 45, 46 is provided for connecting a respective rod with two of the screws at the receiver member thereof forming a first connecting point, and a second pair of threaded rods 29, 30 is provided for connecting a respective one thereof with two of the screws at a second connecting point which is offset with respect to the first connecting point towards the threaded shaft portion.
Abstract: A preparation comprising essentially xylitol and glucose in a variable relation, each no more than 200 grams and no less than 20 grams each, as part of total intravenous nutrition support to cover the energy expenditure in humans with reduced ability to utilize amino acids.
Abstract: Compounds of general formula (I) ##STR1## wherein R.sup.1 represents an optinally substituted carbocyclic or heterocyclic aryl group, or an optionally substituted alkyl, alkenyl, cycloalkyl or cycloalkenyl group; R.sup.2 represents an optionally substituted alkyl, alkenyl, alkynyl, cycloalkyl or cycloalkenyl group or an optionally substituted carbocyclic or heterocyclic aryl or aralkyl group; R.sup.3 represents a hydrogen atom or an alkyl group; and either X represents an oxygen or sulphur atom, a group --CH.sub.2 -- or a group NR.sup.4 where R.sup.4 represents a hydrogen atom or a C.sub.1-4 alkyl group; and Y represents a group --CH.sub.2 -- or --CH.sub.2 CH.sub.2 -- X-Y together represent the group --CH.dbd.CH--; and salts and physiologically functional derivatives thereof are useful in the treatment of tumours. Processes for preparing the compounds, intermediates useful in their preparation, pharmaceutical compositions containing them and their use in the treatment of tumours are also described.
Abstract: The present invention relates to 6-substituted purine carbocyclic nucleosides and their use in medical therapy particularly in the treatment of HIV and HBV infections. Also provided are pharmceutical formulations and processes for the preparation of compounds according to the invention.
Abstract: The present invention relates to 6-substituted purine carbocyclic nucleosides and their use in medical therapy particularly in the treatment of HIV and HBV infections. The invention also relates to pharmaceutical formulations and processes for the preparation of compounds according to the invention.
Abstract: Treatment of AIDS or humans carrying or infected with the AIDS virus or having antibodies to the AIDS virus is disclosed using the compound 3'-azido-3'-deoxythymidine or a pharmaceutically acceptable basic salt thereof. Also disclosed is the use of the 5'-mono-, di- and triphosphate of 3'-azido-3'-deoxythymidine or a pharmaceutically acceptable basic salt thereof for the same purpose. Additionally, there is disclosed the treatment of Kaposi's sarcoma with 3'-azido-3'-deoxythymidine (AZT) and the synergistic activity in the treatment of humans infected with HTLV-III of AZT and interferon as well as AZT and acyclovir.
Type:
Grant
Filed:
April 18, 1990
Date of Patent:
February 4, 1992
Assignee:
Burroughs Wellcome Co.
Inventors:
Janet L. Rideout, David W. Barry, Sandra N. Lehrman, Martha H. St. Clair, Phillip A. Furman