Patents Represented by Attorney Edward A. Conroy, Jr.
  • Patent number: 4321379
    Abstract: This disclosure describes 8-substituted-4-phenyl-1-oxa-8-azaspiro[4,5]dec-3-en-2-ones and 8-substituted-4-phenyl-1-oxa-8-azaspiro[4,5]decan-2-ones useful as analgesic or neuroleptic agents.
    Type: Grant
    Filed: January 28, 1981
    Date of Patent: March 23, 1982
    Assignee: American Cyanamid Company
    Inventors: John J. Brown, Robert A. Hardy, Jr.
  • Patent number: 4317774
    Abstract: This disclosure describes compounds of the class of 6-[D-.alpha.-(substituted-coumarin-3-carboxamido)phenylacetamido]penicilla nic acids which possess antimicrobial activity.
    Type: Grant
    Filed: March 24, 1978
    Date of Patent: March 2, 1982
    Assignee: American Cyanamid Company
    Inventors: Martin L. Sassiver, James H. Boothe
  • Patent number: 4302589
    Abstract: Novel substituted 3-[2-(4-phenyl or pyridyl-1-piperazinyl or piperidino)ethyl]indolines useful as antipsychotic agents in mammals as well as substituted 3-[2-(4-phenylpiperidino)ethyl]indole intermediates for their preparation.
    Type: Grant
    Filed: May 8, 1980
    Date of Patent: November 24, 1981
    Assignee: American Cyanamid Company
    Inventors: William J. Fanshawe, Thomas C. McKenzie, Lantz S. Crawley
  • Patent number: 4299769
    Abstract: This disclosure describes novel substituted .omega.-heteroaroyl(propionyl or butyryl)-L-prolines and the esters and cationic salts thereof which are useful as hypotensive agents in mammals.
    Type: Grant
    Filed: April 28, 1980
    Date of Patent: November 10, 1981
    Assignee: American Cyanamid Company
    Inventors: Francis J. McEvoy, William B. Wright, Jr., Gary H. Birnberg, Jay D. Albright
  • Patent number: 4296030
    Abstract: This disclosure describes metal chelates of symmetrical 1,4-bis(substituted-amino)-5,8-dihydroxy-anthraquinones useful for inhibiting the growth of tumors and as colorants or dyes.
    Type: Grant
    Filed: April 9, 1980
    Date of Patent: October 20, 1981
    Assignee: American Cyanamid Company
    Inventors: Stanley A. Lang, Jr., Keith C. Murdock
  • Patent number: 4293554
    Abstract: A method of treating asthma in a warm-blooded animal using the compound 6-phenyl-1,2,4-triazolo[4,3-b]pyridazin-3(2H)-one.
    Type: Grant
    Filed: February 21, 1980
    Date of Patent: October 6, 1981
    Assignee: American Cyanamid Company
    Inventors: George R. Allen, Jr., John W. Hanifin, Jr., Daniel B. Moran, Jay D. Albright
  • Patent number: 4289769
    Abstract: This disclosure describes novel derivatives of p-formylbenzamide amidinohydrazone and their use as hypotensive agents.
    Type: Grant
    Filed: August 8, 1980
    Date of Patent: September 15, 1981
    Assignee: American Cyanamid Company
    Inventors: William B. Wright, Jr., Andrew S. Tomcufcik
  • Patent number: 4284785
    Abstract: Isoxazolecarboxylic acid phenyl esters which are intermediates for the preparation of anti-inflammatory agents.
    Type: Grant
    Filed: December 19, 1979
    Date of Patent: August 18, 1981
    Assignee: American Cyanamid Company
    Inventors: John W. Hanifin, Jr., David N. Ridge
  • Patent number: 4283334
    Abstract: 2,3-Disubstituted-2,3,6,7,8,9-hexahydro-5H-thiazolo[3,2-a]-[1,3]diazocin-3- ols which are new compounds useful as diuretic agents.
    Type: Grant
    Filed: December 5, 1979
    Date of Patent: August 11, 1981
    Assignee: American Cyanamid Company
    Inventors: Andrew S. Tomcufcik, William B. Wright, Jr., Joseph W. Marsico, Jr.
  • Patent number: 4278689
    Abstract: This disclosure describes symmetrical 1,4-bis(substituted-amino)-5,8-dihydroxyanthraquinones useful as chelating agents and for inhibiting the growth of transplanted mouse tumors.
    Type: Grant
    Filed: August 2, 1979
    Date of Patent: July 14, 1981
    Assignee: American Cyanamid Company
    Inventors: Keith C. Murdock, Frederick E. Durr
  • Patent number: 4278605
    Abstract: This disclosure describes novel heteroalkylenebisanthraquinones useful as chelating agents and for inhibiting the growth of transplanted mouse tumors.
    Type: Grant
    Filed: June 30, 1980
    Date of Patent: July 14, 1981
    Assignee: American Cyanamid Company
    Inventor: Keith C. Murdock
  • Patent number: 4275010
    Abstract: This disclosure describes 1,4-bis(guanidinylamino)-5,8-dihydroxyanthraquinones useful as chelating agents and for inhibiting the growth of transplanted mouse tumors.
    Type: Grant
    Filed: October 24, 1979
    Date of Patent: June 23, 1981
    Assignee: American Cyanamid Company
    Inventor: Keith C. Murdock
  • Patent number: 4275009
    Abstract: This disclosure describes 1-(aminoalkylamino)-5,8-dihydroxy-4-substituted-anthraquinones useful as chelating agents and for inhibiting the growth of transplanted mouse tumors.
    Type: Grant
    Filed: May 29, 1979
    Date of Patent: June 23, 1981
    Assignee: American Cyanamid Company
    Inventor: Keith C. Murdock
  • Patent number: 4269980
    Abstract: This disclosure describes novel 5-, 7-, and 8-(substituted-phenyl)-1,2,4-triazolo[4,3-c]pyrimidines and 5-, 7-, and 8-(substituted-phenyl)-1,2,4-triazolo[1,5-c]pyrimidines and their use as anxiolytic agents.
    Type: Grant
    Filed: December 17, 1979
    Date of Patent: May 26, 1981
    Assignee: American Cyanamid Company
    Inventors: Robert A. Hardy, Jr., Jannie S. Baker, Nicanor Q. Quinones
  • Patent number: 4269832
    Abstract: This disclosure describes compositions of matter useful as anti-inflammatory agents and as inhibitors of the progressive joint deterioration characteristic of arthritic disease and the methods of meliorating inflammation and of inhibiting joint deterioration in mammals therewith, the active ingredients of said compositions of matter being certain 2-(substituted-amino)-4,6-bis(alkylamino)-s-triazines.
    Type: Grant
    Filed: November 19, 1979
    Date of Patent: May 26, 1981
    Assignee: American Cyanamid Company
    Inventors: Andrew S. Tomcufcik, Adolph E. Sloboda
  • Patent number: 4261896
    Abstract: Novel 1-substituted-2-(substitutedimino)-1H-1,2-dihydrobenz[cd]indoles useful as inhibitors of platelet aggregation.
    Type: Grant
    Filed: November 23, 1979
    Date of Patent: April 14, 1981
    Assignee: American Cyanamid Company
    Inventors: Andrew S. Tomcufcik, Raymond G. Wilkinson
  • Patent number: 4261892
    Abstract: This disclosure describes new compounds and compositions of matter useful as anti-inflammatory agents and as inhibitors of the progressive joint deterioration characteristic of arthritic disease and the methods of meliorating inflammation and of inhibiting joint deterioration in mammals therewith, the active ingredients of said compositions of matter being certain 2,4,6-tris(substituted-amino)-s-triazines.
    Type: Grant
    Filed: March 5, 1979
    Date of Patent: April 14, 1981
    Assignee: American Cyanamid Company
    Inventors: Andrew S. Tomcufcik, Adolph E. Sloboda
  • Patent number: 4259476
    Abstract: Novel heterocyclic anthracycline compounds having antitumor activity against murine P388 leukemia in mice.
    Type: Grant
    Filed: April 2, 1979
    Date of Patent: March 31, 1981
    Inventors: Andrew S. Kende, Howard Newman
  • Patent number: 4259256
    Abstract: This disclosure describes novel substituted 2-benzoyl-3-alkoxy-2-alkenonitriles and substituted 2-benzoyl-3-amino-2-alkenonitriles which are useful as intermediates for the preparation of certain substituted cis-2-benzoyl-3-hydroxy-2-alkenonitriles which possess anti-inflammatory activity.
    Type: Grant
    Filed: July 2, 1979
    Date of Patent: March 31, 1981
    Assignee: American Cyanamid Company
    Inventors: John W. Hanifin, Jr., David N. Ridge
  • Patent number: 4259504
    Abstract: This disclosure describes new compounds and compositions of matter useful as anti-inflammatory agents and as inhibitors of the progressive joint deterioration characteristic of arthritic disease and the methods of meliorating inflammation and of inhibiting joint deterioration in mammals therewith, the novel active ingredients of said compositions of matter being certain substituted 1-phenyl-1H-1,2,4-triazoles and/or the pharmacologically acceptable acid-addition salts thereof.
    Type: Grant
    Filed: August 27, 1979
    Date of Patent: March 31, 1981
    Assignee: American Cyanamid Company
    Inventors: Stanley A. Lang, Jr., Yang-I Lin, David N. Ridge