Patents Represented by Attorney, Agent or Law Firm Felfe & Lynch
  • Patent number: 5616352
    Abstract: The present invention provides a process for the production of fat- and cholesterol-reduced powdered products based on eggs with a high content of phospholipids by extraction with compressed gases, wherein the powdered starting material is extracted with a solvent mixture consisting of propane and carbon dioxide with a mixing ratio of 95/5 to 5/95% by weight at a pressure of <300 bar and at s temperature of <70.degree. C.
    Type: Grant
    Filed: September 18, 1995
    Date of Patent: April 1, 1997
    Assignee: SKW Trostberg Aktiengesellschaft
    Inventors: Jurgen Heidlas, Heinz-Rudiger Vollbrecht, Jan Cully
  • Patent number: 5613743
    Abstract: In a vehicular control system in which target braking torques are set for each of the driven wheels, the smaller target braking torque for the driven wheels is determined. Based on this smaller target braking torque, a target engine torque is calculated, and the engine torque is varied to conform to the target engine torque. Residual braking torques are calculated as differences from the target braking torques for each driven wheel and the target engine torque. These residual braking torques are realized by varying the brake pressure. Therefore the target braking torque is split into an engine torque which is equal for both driven wheels and into a braking torque which may be different for each driven wheel.
    Type: Grant
    Filed: April 6, 1995
    Date of Patent: March 25, 1997
    Assignee: Robert Bosch GmbH
    Inventors: Friedrich Kost, Uwe Hartmann, Karl-Josef Weiss, Thomas Ehret
  • Patent number: 5614394
    Abstract: A method for making an monoclonal antibody specific for vitamin B12 by immunizing mice with vitamin B12-b-acid and isolating hybridomas that produce monoclonal antibodies which have an affinity constant for B12 greater than 5.times.10.sup.9 l/mol is disclosed.
    Type: Grant
    Filed: May 16, 1995
    Date of Patent: March 25, 1997
    Assignee: Boehringer Mannheim GmbH
    Inventors: Nicholas R. Hoyle, Gunter Pappert, Michael Grol, Christa Hubner-Parajsz
  • Patent number: 5614643
    Abstract: Process for the enzymatic production of isomerically pure compounds having the general formulae I and II ##STR1## in which the substituents R have the meanings stated in the claims, as well as their use for the production of isomerically pure isosorbide-2-nitrate having the formula V and isosorbide-5-nitrate having the formula VI, ##STR2## which are both important as therapeutic agents for coronary diseases.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: March 25, 1997
    Assignee: Boehringer Mannheim GmbH
    Inventors: Manfred Schneider, Robert Seemayer
  • Patent number: 5614507
    Abstract: Protein and peptide free compositions are described, which are useful in treating endotoxemia. The compositions contain a phospholipid and a neutral lipid, preferably phosphatidylcholine and triglyceride.
    Type: Grant
    Filed: May 2, 1995
    Date of Patent: March 25, 1997
    Assignee: The Rogosin Institute
    Inventors: Thomas S. Parker, Daniel M. Levine, Albert L. Rubin, Bruce R. Gordon, Stuart D. Saal
  • Patent number: 5611899
    Abstract: An AC voltage source connected to at least one cathode is switched off rapidly upon the occurrence of a critical number of so-called "microarcs" which precede a "large arc". In order to be able to differentiate between large arcs and microarcs, a special counting and evaluation device is provided.
    Type: Grant
    Filed: November 20, 1995
    Date of Patent: March 18, 1997
    Assignee: Leybold Aktiengesellschaft
    Inventor: Wolfram Maass
  • Patent number: 5611858
    Abstract: In an apparatus for the transport of discoidal substrates (3, 3', . . . ) through a treatment station or from a first to a second processing station (4 and 5, respectively) of a vacuum coating apparatus a motor unit (6) is provided, having three planar, positive conveyors driven by the latter, each having at least two sprockets (10, 10' and 12, 12') and a cogbelt (13, 14) guided over each sprocket pair, two of these conveyors being disposed to one another such that their sprockets (10, 10') extend in a common plane, the sprockets (12, 12') of a third conveyor extending in a plane which runs at right angles to the plane of the sprockets (10, 10') of the other two conveyors, and all three of the parallel strands of the three conveyors, which are at an angle to one another, being tangent to the outside edge of circular discoidal substrates (3, 3', . . .
    Type: Grant
    Filed: October 4, 1994
    Date of Patent: March 18, 1997
    Assignee: Leybold Aktiengesellschaft
    Inventor: Jaroslav Zejda
  • Patent number: 5612068
    Abstract: In an apparatus for the transfer of substrates (9) from an initial station (3) through several process stations (4 to 8) and back to this initial station (3), manipulators (10 to 14) having pivoting gripper arms (15 to 19) and carousel transfer systems (20,21) for the transfer of the substrates (9) are provided. One of the carousels (20) provided with substrate holders (22) cooperates both with a two-armed first manipulator (11) and with a two-armed second manipulator (10). The second manipulator (10) lifts several substrates (9) simultaneously from the first carousel (20) in one period of time and feeds them to the corresponding second process station (5) which is configured for the simultaneous processing of several substrates.
    Type: Grant
    Filed: December 7, 1994
    Date of Patent: March 18, 1997
    Assignee: Leybold Aktiengesellschaft
    Inventors: Stefan Kempf, Eggo Sichmann
  • Patent number: 5612201
    Abstract: The invention relates to nucleic acid molecules which are useful in determining expression of the family of molecules known as the MAGE tumor rejection antigen precursors. These nucleic acid are molecules useful as diagnostic aids for determining whether or not an individual has cancer. Methods using these molecules are also described.
    Type: Grant
    Filed: September 1, 1994
    Date of Patent: March 18, 1997
    Assignee: Ludwig Institute for Cancer Research
    Inventors: Etienne De Plaen, Thierry Boon-Falleur, Bernard Lethe, Jean-Pierre Szikora, Charles De Smet, Patrick Chomez
  • Patent number: 5610013
    Abstract: A new family of tumor rejection antigen precursors, and the nucleic acid molecules which code for them, are disclosed. These tumor rejection antigen precursors are referred to as GAGE tumor rejection antigen precursors, and the nucleic acid molecules which code for them are referred to as GAGE coding molecules. Various diagnostic and therapeutic uses of the coding sequences and the tumor rejection antigens, and their precursor molecules are described.
    Type: Grant
    Filed: May 27, 1994
    Date of Patent: March 11, 1997
    Assignee: Ludwig Institute for Cancer Research
    Inventors: Benoit Van den Eynde, Thierry Boon-Falleur
  • Patent number: 5610656
    Abstract: A protective housing (1) for optical equipment, especially for video surveillance cameras, has a tubular housing shell (2), a rear wall (4) with means (5) for introducing or passing through electrical lines (6), an internal equipment carrier (16), and an external housing carrier (17), which are held above and below the housing shell (2) at a fixed distance, parallel to each other. To facilitate installation and removal, a frame part (3), to which the equipment carrier (16) and the housing carrier (17) are attached, is installed between the rear wall (4) and the housing shell (2). It is preferable for a replaceable plate (11) to be attached to the frame part (3); for a first part (12) of a multiconductor plug device (13) to be installed on side of the plate (11) facing the rear wall; and for a second part (15) of the multiconductor plug device (13), which can mate with the first part (12), to be installed on the inside surface (14) of the rear wall (4).
    Type: Grant
    Filed: February 14, 1995
    Date of Patent: March 11, 1997
    Assignee: Videor Technical E. Hartig GmbH
    Inventor: Rainer Bernhardt
  • Patent number: 5609666
    Abstract: During the gradual build-up of porous quartz glass by the combustion of a hydrolysis gas mixture and preferably for a certain period of time thereafter, a drying gas mixture is conducted under positive pressure through the porous tubular deposit from the inside to the outside as it is being built-up. This is accomplished by depositing the quartz on a tubular substrate in which a drying gas is introduced at positive pressure.
    Type: Grant
    Filed: February 16, 1995
    Date of Patent: March 11, 1997
    Assignee: Heraeus Quarzglas GmbH
    Inventor: Walter Heitmann
  • Patent number: 5609647
    Abstract: The invention relates to a hip joint socket for insertion into bone tissue, with an outer metal shell and an inner ceramic shell, the ceramic shell being anchored in the metal shell. To reduce its size while simultaneously reducing the wall thickness of the ceramic shell the inside of the metal shell and the outside of the ceramic shell have a spherical shape accurately fitted to one another and means are disposed for equalizing the transmission of force between the ceramic shell and the metal shell.
    Type: Grant
    Filed: October 17, 1994
    Date of Patent: March 11, 1997
    Assignee: Cerasiv GmbH, Innovatives Keramik-Engineering
    Inventors: Hartmut K alberer, Hans-Georg Pfaff
  • Patent number: 5610116
    Abstract: In order to provide a temperature- and acid-resistant catalyst carrier based on a gas-pervious carrier body and a porous surface layer having a high silica content, while dispensing with a washcoat, the carrier body and the surface layer are designed as a chemically and physically homogeneous structure shaped in a single operation. The SiO.sub.2 content amounts to at least 99% by weight and has a specific surface from 5 m.sup.2 /g to 50 m.sup.2 /g. In a process for producing a catalyst carrier made of synthetic, amorphous silica particles with more than 99% by weight SiO.sub.2, a paste is prepared with the particles, a liquid, and a binder. Plastifying agents are added to the paste and the paste is continuously extruded into a monolithic greenware strand. The alkali and alkaline earth content of the paste is set at no more than 200 ppm and the greenware is cut to length and sintered at a temperature in a range between 800.degree. C. and 1400.degree. C.
    Type: Grant
    Filed: October 5, 1994
    Date of Patent: March 11, 1997
    Assignee: Heraeus Quarzglas GmbH
    Inventors: Waltraud Werdecker, Rolf Gerhardt, Wolfgang Krock
  • Patent number: 5607630
    Abstract: A ceramic moulded body containing at least 10 vol. % fine-grained Al.sub.2 O.sub.3, and a process for its production(a) milling aluminium metal in powder form alone or together with Al.sub.2 O.sub.3 or/and if desired further suitable inorganic substances for ceramic formation in a non-aqueous liquid in the presence of oxygen until 10 to 80% of the metallic aluminium powder has reacted to form one or several aluminium oxidation precursors from the group amorphous Al.sub.2 O.sub.3, .gamma.-Al.sub.2 O.sub.3 and aluminium-organic compounds and the powder has a maximum oxidation rate between 510.degree. and 610.degree. C. according to differential thermoanalytical measurement;(b) molding the powder of step (a) into a green body;(c) slowly heating the green body in an atmosphere containing oxygen to a temperature which is below the melting temperature of aluminium until at least 50% of the metallic aluminium powder remaining after the milling has reacted to Al.sub.2 O.sub.
    Type: Grant
    Filed: September 30, 1994
    Date of Patent: March 4, 1997
    Inventor: Nils Claussen
  • Patent number: 5605839
    Abstract: This invention relates to methods and apparatus for carrying out chemical reactions between a plurality of reactants and in particular it is amenable to micro or nano scale operation and to the sequential chemical reactions required during such processes as construction or sequencing of proteins, oligonucleotides and polysaccharides. The present invention further relates to a capillary liquid chromatography system for high-sensitivity component separation and microsequencing for use in association with the methods and apparatus herein described.
    Type: Grant
    Filed: May 29, 1992
    Date of Patent: February 25, 1997
    Assignee: Ludwig Institute for Cancer Research
    Inventors: Richard J. Simpson, Antony W. Burgess, Robert L. Moritz
  • Patent number: 5606032
    Abstract: The invention involves the purification of various glial mitogenic factors. In one aspect of the invention, vertebrate brain material is extracted, and the extract is then subjected to chromatographic separation. The glial mitogenic factors which can be obtained include a basic polypeptide with a molecular weight of from about 30 to about 36 kD, by reference to SDS-PAGE, and a second basic polypeptide factor which is from about 55 to about 63 kD as determined by SDS-page.
    Type: Grant
    Filed: June 6, 1995
    Date of Patent: February 25, 1997
    Assignees: Ludwig Institute for Cancer Research, Cambridge Neuroscience
    Inventors: Andrew Goodearl, Paul Stroobant, Luisa Minghetti, Michael Waterfield, Mark Marchioni, Mario S. Chen, Ian Hiles
  • Patent number: 5603136
    Abstract: A hollow shaft (4) connected to a drive motor is supported in a machine housing (2) in such a way as to act on a rotary coupling (13) with at least two coupling jaws (28, 29). These jaws are held with freedom of radial and axial movement in recesses (23) in a jaw holder (14), which is able to rotate with the hollow shaft, the recesses being bounded by parallel surfaces (24, 25). The jaws can be pressed radially against the spiral wire rod under the action of a control device (16). To increase the operating reliability and to make it easier to replace the coupling jaws, one end of the hollow shaft (4) is connected nonrotatably with respect to a coupling housing (9), the circumference of which is at least mostly closed, and the jaw holder (14) with the coupling jaws (28, 29) is supported in the coupling housing (9) in such a way that it is not free to rotate but can be removed in the axial direction.
    Type: Grant
    Filed: February 2, 1996
    Date of Patent: February 18, 1997
    Assignee: Rothenberger Werkzeuge-Maschinen GmbH
    Inventor: Jurgen Truschler
  • Patent number: 5602096
    Abstract: Disclosed is the characterization and purification of DNA encoding numerous polypeptides useful for the stimulation of glial cell (particularly, Schwann cell mitogenesis and treating glial cell tumors. Also disclosed are DNA sequences encoding novel polypeptides which may have use in stimulating glial cell mitogenesis and treating glial cell tumors. Methods for the synthesis, purification and testing of both known and novel polypeptides for their use as both therapeutic and diagnostic aids in the treatment of diseases involving glial cells are also provided. Methods are also provided for the use of these polypeptides for the preparation of antibody probes useful for both diagnostic and therapeutic use in diseases involving glial cells. The present invention is specifically directed to a method of using a secretable glial growth factor to induce acetycholine receptor synthesis.
    Type: Grant
    Filed: June 6, 1995
    Date of Patent: February 11, 1997
    Assignees: Ludwig Institute for Cancer Research, Cambridge Neuroscience Research Inc.
    Inventors: Andrew Goodearl, Paul Stroobant, Luisa Minghetti, Michael Waterfield, Mark Marchioni, Mario S. Chen, Ian Hiles
  • Patent number: 5602018
    Abstract: Hypoglycosylated recombinant glucose oxidase with a molecular weight of ca. 68-80 kDa, a specific activity of ca. 200 U/mg unit of weight, a carbohydrate portion of ca. 12% which is obtainable by expression of a recombinant DNA containing the GOD gene in the N-glycosylation-defective yeast mutants DSM 7042, DSM 7338, DSM 7160 or DSM 7340 or allelic mutant strains, fermentation and isolation of the enzyme from the culture supernatant or the cells.
    Type: Grant
    Filed: February 7, 1995
    Date of Patent: February 11, 1997
    Assignee: Boehringer Mannheim GmbH
    Inventors: Erhard Kopetzki, Klaus Lehnert