Abstract: This invention relates to a method of determining, in a subject having active breast gross cystic disease, the risk of future breast cancer development. The level of glycoprotein GCDFP-15 in the plasma is measured at the time of cyst aspiration in order to provide an indication as to the likelihood of future breast cancer development.

Abstract: A new family of tumor rejection antigen precursors, and the nucleic acid molecules which code for them, are disclosed. These tumor rejection antigen precursors are referred to as GAGE tumor rejection antigen precursors, and the nucleic acid molecules which code for them are referred to as GAGE coding molecules. Various diagnostic and therapeutic uses of the coding sequences and the tumor rejection antigens, and their precursor molecules are described. Tumor rejection antigens are also shown.

Abstract: Disclosed is a process for the preparation of 5-formylaminopyrimidines of the general formula: ##STR1## in which R.sup.1, R.sup.2 and R.sup.3 are the same or different and signify H, OH, SH, NH.sub.2, alkylamino, halogen, O-alkyl, S-alkyl or alkyl, as well as aryl, and alkyl is an aliphatic radical containing up to 4 carbon atoms, from the corresponding 5-nitrosopyrimidines of the general formula: ##STR2## in which R.sup.1, R.sup.2 and R.sup.3 have the same meanings as above, wherein the starting compound is subjected to a reductive formylation in the presence of a noble metal catalyst, as well as of formic acid and of a salt thereof.

Abstract: The wheel speeds are measured by wheel speed sensors and are fed to an evaluation circuit. By way of the evaluation circuit, brake pressure control signals at least for increasing pressure and for decreasing pressure for a specific duration are then produced for the closed-loop/open-loop control of the wheel movement behavior. Moreover, brake pressure control signals are also usually output by the evaluation circuit in order to keep the brake pressure constant. These brake pressure control signals are fed to brake pressure control units for varying the brake pressure. The core of the invention consists in the fact that the duration at least of the first decrease in brake pressure at the front wheels is selected to be dependent on the speed of the vehicle at the start of braking.

Abstract: Disclosed is a process and apparatus for producing a topical coating on a food product. The topical coating may be a sweetener wherein a superheated pressurized solution of the sweetener is sprayed on a heated food product to form a coating thereon. The topical coating may also contain a flavoring.

Abstract: The invention provides for the production of several humanized murine antibodies specific for the antigen LK26, which is recognized by the murine antibody LK26. This antigen is expressed on all choriocarcinoma, teratocarcinoma and renal cancer cell lines whereas it is not expressed on cell lines of leukaemias, lymphomas, neuroectodermally-derived and epithelial tumour cell lines (excepting a small subset of epithelial cell lines). Furthermore, whereas renal cancer cell lines express the LK26 antigen, normal renal epithelial cells do not. Similarly, with the exception of the trophoblast, all normal adult and fetal tissues tested are negative for the LK26 phenotype. The invention also provides for numerous polynucleotide encoding humanized LK26 specific antibodies, expression vectors for producing humanized LK26 specific antibodies, and host cells for the recombinant production of the humanized antibodies.

Abstract: Immunogens of formula I are provided for obtaining HbA.sub.1c -specific antibodies ##STR1## M is 1 to 40, T is a carrier protein and A is a 10-20 atoms spacer and is ##STR2## where X is S or --NH--, n is 1 to 4 and B is a succinimide containing organic radical. The antibodies obtained bind glycosylated hemoglobin to determine HbA.sub.1c in body fluids.

Abstract: Biological agents such as secretory cells are encapsulated in a hydrophilic gel made of agarose or collagen-agarose and gelatin sponge-agarose combinations. In a preferred embodiment, semi-solid beads are formed from a suspension containing collagen, agarose and secretory cells such as pancreatic islets, the collagen is polymerized to form solid, agarose-collagen beads and the solid beads are coated with agarose. Coating is preferably by rolling the solid beads in about 5-10% agarose, contacting the rolled beads with mineral oil and washing oil from the beads. Beads containing secretory cells can be transplanted into a mammal to treat a condition caused by impaired secretory cell function.

Abstract: To produce a free-flowing granulate which has a high bulk density and a defined particle size distribution, which generates little dust, is easy to handle, and is suitable as a starting material for quartz glass products, the mixing operation includes a first mixing phase, in which the materials to be mixed are subjected to a slow mixing action to form a coarse-grained mass, and a second mixing phase, in which the coarse-grained mass is converted to a fine-grained mass by a more intensive mixing action which grinds and compacts the grains. The content of silica powder in the materials to be mixed is adjusted at least during the second mixing phase to a value of at least 75 wt. %.

Abstract: A drill head carries a plurality of coaxially mounted drill crowns beginning with a first crown and followed by additional drill crowns which, upon rotation, describe concentric envelope circles of successively larger diameters. The first drill crown has cutting elements with a diamond coating with an average particle size of 200-1,000 .mu.m, and the additional drill crowns have cutting elements with a diamond coating with an average particle size of 200-300 .mu.m. The difference in diameter of succeeding drill crowns is successively small. Alignment of the drill crowns in a pilot hole is achieved by guide elements mounted behind the drill crowns and describing an inner envelope circle which is smaller than the outer envelope circle described by the largest drill crown, thereby defining a radial safety gap into which fluid is fed to form a cushion during rotation.

Abstract: Disclosed is an all-ceramic drill bit which combines the positive properties of ceramic with a tool geometry adapted to the special features of the material. The drill bit is formed with a groove for the shavings which extends in the axial direction linearly along a surface line.

Abstract: Disclosed is a barium-free glass of good x-ray absorption, which has a composition (in wt.-% on the oxide basis) of SiO.sub.2 50-75; ZrO.sub.2 5-30; Li.sub.2 O 0-5; Na.sub.2 O 0-25; K.sub.2 O 0-25; .SIGMA. alkali oxides 0-25. Preferred is a dental glass of the composition of SiO.sub.2 55-70; ZrO.sub.2 10-25; Li.sub.2 O 0-15; Na.sub.2 O 10-25; K.sub.2 O 0-15; .SIGMA. alkaloids 15-25. The glass can furthermore contain also up to 3 wt.-% of fluorine, up to 5 wt.-% of MgO, up to 5 wt.-% of TiO.sub.2, and in each case up to 10 wt.-% of the oxides Al.sub.2 O.sub.3, GeO.sub.2, P.sub.2 O.sub.5, La.sub.2 O.sub.3, Y.sub.2 O.sub.3, Ta.sub.2 O.sub.3, Gd.sub.2 O.sub.3, ZnO and Nb.sub.2 O.sub.5. The glass finds its use in powder form with an average particle size of .ltoreq.10 .mu.m as filler for dental composites for filling teeth.

Abstract: Electroplated steel sheet suitable for soldering is provided herein by coating the plated steel sheet with a post-treatment solution in the range of 0.02 to 2 .mu.m in dry thickness. The post-treatment solution contains from 2 to 100 g/l of at least one water-soluble or water-dispersed material. The post-treatment solution may further contain chromium ion, hereafter referred to as Cr.sup.6+, from 0.01 to 3 g/l, and/or organic amine soap from 10 to 100 g/l. A suitable pH value of the post-treatment solution is from 3 to 10.

Abstract: A rotating cylindrical quartz glass tube is partitioned into at least 3 chambers comprising a pre-heating chamber, a reaction chamber, and a gas desorption chamber. The process comprises pre-heating the starting quartz powder by continuously supplying it into the pre-heating chamber, refining the powder by transferring it into the reaction chamber in which the powder is brought into contact with a chlorine-containing gas atmosphere, and transferring the powder into the gas desorption chamber; the chambers may be partitioned using a sectioning plate having an opening. Alkali metal elements such as sodium and potassium, as well as transition metal elements such as iron, copper, chromium, and nickel are removed from a powder of naturally occurring quartz. The process also removes alkaline earth metal elements such as magnesium and calcium. Furthermore, it is of high productivity because it can be operated continuously to yield high purity quartz powder at a low cost.

Abstract: The invention concerns a method for the detection of a programmed or induced cell death of eukaryotic cells as well as a suitable test kit for this method of detection.

Abstract: A film processing apparatus includes a film inserting device operable to receive negative film strips cut into a predetermined length and transported from a film transporting device and then to insert the film strips one after another into each independent film-holding pocket of a film sheet holder. A planar member is disposed adjacent an inserting opening of the film sheet holder and displaceable by contacting the film being transported. In association with the planar member, a jamming detection sensor is provided for detecting a jammed condition of the film according to a displacement of the planar member.

Abstract: An ABS which evaluates slip values prescribes pressure values for the wheel brakes. In order to improve the driving stability, these pressure values are varied by a brake controller using the deviation of the yawing speed from a set value and the front-axle steering angle as input variables. The brake controller determines its output values (variation values) with the aid of the fuzzy logic. Additionally, rear-axle steering is integrated into the system, the system partially also using fuzzy logic. Subsequently, an adaptation which is based on fuzzy logic and uses the brake controller and the rear-axle steering controller in a weighted fashion is proposed.

Abstract: The present invention provides immunogens for obtaining HbA.sub.1c -specific antibodies, which immunogens have the general formula: ##STR1## wherein M is 1 to 40, T is a carrier protein and A is a spacer which has a chain length of 10 to 20 atoms and has the general formula: ##STR2## wherein X is a sulphur atom or au --NH-- group, n is 1 to 4 and B is an organic radical which contains a succinimide group. The present invention also provides a process for obtaining antibodies which specifically bind glycosylated haemoglobin, wherein an immunogen of general formula (I) is injected into an organism capable of antibody formation and the antibodies are then obtained in known manner. These antibodies can be used for determining HbA.sub.1c in body fluids.

Abstract: Wheel speeds on each side of the vehicle are added, and the sums are subtracted to form a difference VXU which is time filtered to produce a filtered difference VXG. As long as VXU does not exceed VXG by more than a speed dependent threshold, a signal indicating straight line travel is produced. This signal can be cancelled when VXG exceeds a vehicle dependent threshold and is also blocked when the vehicle speed falls below a minimum, when the ABS is operating, or when the vehicle is decelerating. The signal indicating straight line travel accounts for tire tolerance and can be used to control vehicle dynamics, for example by preventing an increase in brake pressure or engine braking when the vehicle is travelling in a curve.

Abstract: A serial data stream of control commands is sent to a shift register having a delay time corresponding to a shift frequency which is a multiple of the maximum expected bit rate, each control command beginning with a uniform binary character having a start sequence with a maximum duration. The bit rate is calculated from the duration of the start sequence which is measured by activating a counting circuit during the time in which the data stream is passing through the shift register. The bit rate is programmed into an integrated serial data transmission component, preferably a UART, and the delay time of the shift register is determined according to the maximum duration of the start sequence, plus the time required to program the bit rate into the UART.