Patents Represented by Attorney Heslin Rothenberg Farley & Mesiti P.C.
  • Patent number: 8257716
    Abstract: The present invention relates to an isolated antibody or antigen-binding fragment thereof that specifically binds with high affinity to at least a portion of a segment of human prostate-derived Ets transcription factor (PDEF). The anti-PDEF antibody of the present invention is effective in prognostic and diagnostic assays for detecting PDEF with immunohistochemistry. The present invention also relates to methods of making the anti-PDEF antibody disclosed herein. The present invention further relates to vaccines against cancers associated with positive expression of PDEF, as well as methods for treating those cancers. Vectors, diagnostic kits, and hybridomas are also disclosed.
    Type: Grant
    Filed: December 22, 2008
    Date of Patent: September 4, 2012
    Inventor: Ashwani Sood
  • Patent number: 8260755
    Abstract: A process-based method and system for mapping and documenting a business process integrates information from a plurality of sources into a process map in such manner that only those sources needed to perform the task at hand are accessed in turn through steps in the process map. Business rules pertaining to the task at hand are built into the process steps. The method involves developing a process map, including a series of flow charts, that integrates all processes, sub processes, procedures, reference materials, and forms into a common repository. Advantageously, the method guides the user in step-by-step fashion as to how to use any attached information and tools to successfully complete the process, accessing sub levels of procedure level flow as needed, without requiring access to any other information, tools, or processes.
    Type: Grant
    Filed: August 12, 2004
    Date of Patent: September 4, 2012
    Assignee: International Business Machines Corporation
    Inventor: Gary F. Stecker
  • Patent number: 8259294
    Abstract: A method and device are provided for measurement of various transmission and reflection values of transparent measurement objects having transparent layers in an inline coating system, and particularly the turbidity of the measurement object during a relative movement between the measurement object and measuring device. Transmission fractions are measured in two different radiation directions of a lighting source emitting diffuse light by two photodetectors, by which a fraction of diffuse light of the lighting source is suppressed in one direction.
    Type: Grant
    Filed: August 11, 2010
    Date of Patent: September 4, 2012
    Assignee: Von Ardenne Anlagentechnik GmbH
    Inventors: Holger Proehl, Thomas Knoth, Tina Schoessler, Martin Dimer
  • Patent number: 8256681
    Abstract: There is described a data collection device that can incorporate an encoded information reading unit that can operate within a system including an access point that is wireline connected to a server. The encoded information reading unit can include at least one of a bar code reading unit, an RFID tag reading unit and a credit/debit card reading unit. Further incorporated in the data collection device can be dynamic access module. The dynamic access communication module enables the data collection device to participate in a self organized network that supports multi-hop data packet transmissions between data collection devices and which further enables the device to transmit data received from a peer device to the system access point.
    Type: Grant
    Filed: May 13, 2010
    Date of Patent: September 4, 2012
    Assignee: Hand Held Products, Inc.
    Inventor: Ynjiun P. Wang
  • Patent number: 8256678
    Abstract: There is described an image sensor based indicia reading terminal comprising a variable setting imaging lens having a first setting at which the terminal has a first plane of optimum focus and a second setting at which the terminal has a second plane of optimum focus. According to one embodiment, a first predetermined picture size where picture size is determined according to a number of pixels subject to read out, can be associated to the first lens setting and a second picture size can be associated to the second lens setting such that the terminal with the lens setting set to the first setting reads out a frame of a first picture size and with the lens setting set to a second setting reads out a frame of a second picture size. In addition to or in place of the picture size operational parameters, different operational parameters can be associated to the respective first and second lens settings.
    Type: Grant
    Filed: August 12, 2009
    Date of Patent: September 4, 2012
    Assignee: Hand Held Products, Inc.
    Inventors: William H. Havens, Timothy P. Meier
  • Patent number: 8260387
    Abstract: A superconducting article is provided which includes a superconducting tape assembly. The superconducting tape assembly includes a superconducting tape layer, having one or more superconducting tapes, and a high-permeability magnetic material layer coupled to the superconducting tape layer. The high-permeability magnetic material layer includes a high-permeability magnetic material which remains magnetically soft at a critical temperature Tc of the superconducting tape, and with presence of an ac magnetic field acting on the superconducting tape assembly, re-magnetizes to divert at least a portion of a normal component of the ac magnetic field therethrough, which reduces ac loss in the superconducting tape layer by modifying the ac magnetic field distribution within the superconducting tape of the superconducting tape layer.
    Type: Grant
    Filed: January 9, 2009
    Date of Patent: September 4, 2012
    Assignee: Superpower, Inc.
    Inventor: Maxim Martchevskii
  • Patent number: 8257500
    Abstract: In a transport device for elongated substrates, especially in hot processes, which includes an essentially rectangular frame, formed by longitudinal and transverse spars connected to each other, in which at least three transverse spars are provided between two longitudinal spars, at least one transverse spar is made from a material, whose heat expansion coefficient differs from the heat expansion coefficient of the material of the other transverse spars or/and at least one transverse spar is connected force-free to at least one transverse support or/and at least one transverse spar is formed from an open profile.
    Type: Grant
    Filed: October 8, 2008
    Date of Patent: September 4, 2012
    Assignee: Von Ardenne Anlagentechnik GmbH
    Inventors: Johannes Struempfel, Reinhardt Bauer, Andreas Heisig, Andre Ulbricht, Steffen Goerke, Heiko Richter, Falk Schwerdtfeger
  • Patent number: 8252548
    Abstract: Disclosed is an in vitro method for the identification and the concomitant monitoring of the therapy and cure of drug-induced or addictive substance-induced liver damage, in which the occurrence of the human enzyme carbamoyl synthase 1 (CPS 1) or its concentration is determined in serum or plasma samples from patients who are being or have been treated with potentially liver-damaging drugs, or from people who take harmful stimulants and addictive substances or are exposed to hepatotoxic substances.
    Type: Grant
    Filed: May 8, 2007
    Date of Patent: August 28, 2012
    Assignee: B.R.A.H.M.S GmbH
    Inventors: Andreas Bergmann, Joachim Struck, Nils G. Morgenthaler
  • Patent number: 8247576
    Abstract: The invention provides compounds of the formula: (I) having protein kinase B inhibiting activity: wherein A is a saturated hydrocarbon linker group containing from 1 to 7 carbon atoms, the linker group having a maximum chain length of 5 atoms extending between R1 and NR2R3 and a maximum chain length of 4 atoms extending between E and NR2R3, wherein one of the carbon atoms in the linker group may optionally be replaced by an oxygen or nitrogen atom; and wherein the carbon atoms of the linker group A may optionally bear one or more substituents selected from oxo, fluorine and hydroxy, provided that the hydroxy group when present is not located at a carbon atom a with respect to the NR2R3 group and provided that the oxo group when present is located at a carbon atom a with respect to the NR2R3 group; E is a monocyclic or bicyclic carbocyclic or heterocyclic group; R1 is an aryl or heteroaryl group; and R2, R3, R4 and R5 are as defined in the claims.
    Type: Grant
    Filed: December 23, 2004
    Date of Patent: August 21, 2012
    Assignees: Astex Therapeutics Limited, Institute of Cancer Research: Royal Cancer Hospital, Cancer Research Technology Limited
    Inventors: Valerio Berdini, Gordon Saxty, Marinus Leendert Verdonk, Steven John Woodhead, Paul Graham Wyatt, Robert George Boyle, Hannah Fiona Sore, David Winter Walker, Ian Collins, Robert Downham, Robin Arthur Ellis Carr
  • Patent number: 8245510
    Abstract: An electro-thermal actuator device includes a case defining a cavity in which are housed a thermal actuator, an electrical heater and, at least partially, an actuating shaft. The device comprises a multipolar connector for the rapid, secure and reliable coupling to a respective source of electrical power supply for the heater. The connector can be configured as an adapter unit distinct from the case, suitable to transform a traditional electro-thermal actuator device into the actuator device described above.
    Type: Grant
    Filed: July 16, 2010
    Date of Patent: August 21, 2012
    Assignee: Eltek, S.p.A.
    Inventors: Costanzo Gadini, Renato Gaj, Marco Moro
  • Patent number: 8245401
    Abstract: A cold plate apparatus is provided which includes a tube and a casted heat sink member. The tube includes a first metal and first and second ends, with a heat transfer region disposed between the ends. The heat sink includes a second metal that surrounds the heat transfer region of the tube, with the first and second ends of the tube residing outside of the heat sink. The second metal has a lower melting point than the first, and the metals reacted peritectically such that a metallurgical bond exists between the tube and the heat sink. The metallurgical bond includes an alloy layer that was formed during casting of the heat sink member. A thickness of the alloy layer was minimized during casting of the heat sink member to enhance the heat transfer characteristic of the metallurgical bond.
    Type: Grant
    Filed: November 5, 2009
    Date of Patent: August 21, 2012
    Assignee: International Business Machines Corporation
    Inventors: Bret W. Lehman, Roger R. Schmidt, Prabjit Singh
  • Patent number: 8245375
    Abstract: A method for repairing a rotor of a turbine includes providing a rotor having a groove portion defined by a circumferential portion of the rotor. The circumferential portion of the rotor is removed to create an opening to provide access to the groove such that the opening, immediately adjacent the groove, is narrower than the groove. A guide block may be extended into a receiving slot separating a first protruding surface from a second protruding surface of the rotor such that a weld area slot of the guide block extends over at least a portion of the opening. The opening may be welded adjacent the guide block to close at least a portion of the opening.
    Type: Grant
    Filed: December 17, 2009
    Date of Patent: August 21, 2012
    Assignee: Mechanical Dynamics & Analysis, Ltd.
    Inventors: James Harvey Coffey, Andrew Otto Ruehs
  • Patent number: 8247417
    Abstract: The invention relates to the use of eszopiclone for the treatment of low-level, chronic pain and fatigue associated with pain.
    Type: Grant
    Filed: October 12, 2011
    Date of Patent: August 21, 2012
    Assignee: Sunovion Pharmaceuticals Inc.
    Inventors: Thomas Wessel, Judy Caron
  • Patent number: 8248082
    Abstract: A method for determining current return path integrity in an electric device with a plurality of signal lines and supply lines. A library with at least one reference signal pattern of a near end crosstalk signal on a defined signal line arising from an input signal on another defined signal line is provided, a predetermined signal to a selected signal line of the electric device is applied, the near end crosstalk signal on at least one further signal line of the electric device is detected, said near end crosstalk signal is compared with the corresponding reference signal pattern from the library, and if there is a deviation between the near end crosstalk signal and the corresponding reference signal pattern, an information that there is any defect in the electric device is displayed.
    Type: Grant
    Filed: November 20, 2007
    Date of Patent: August 21, 2012
    Assignee: International Business Machines Corporation
    Inventors: Roland Frech, Erich Klink, Jurgen Saalmuller
  • Patent number: 8248801
    Abstract: Thermoelectric-enhanced, liquid-cooling apparatus and method are provided for facilitating cooling of one or more components of an electronics rack. The apparatus includes a liquid-cooled structure in thermal communication with the component(s) to be cooled, and a liquid-to-air heat exchanger coupled in fluid communication with the liquid-cooled structure via a coolant loop for receiving coolant from and supply coolant to the liquid-cooled structure. A thermoelectric array is disposed with first and second coolant loop portions in thermal contact with first and second sides of the array. The thermoelectric array operates to transfer heat from coolant passing through the first loop portion to coolant passing through the second loop portion, and cools coolant passing through the first loop portion before the coolant passes through the liquid-cooled structure. Coolant passing through the first and second loop portions passes through the liquid-to-air heat exchanger for cooling thereof.
    Type: Grant
    Filed: July 28, 2010
    Date of Patent: August 21, 2012
    Assignee: International Business Machines Corporation
    Inventors: Levi A. Campbell, Richard C. Chu, Michael J. Ellsworth, Jr., Madhusudan K. Iyengar, Robert E. Simons
  • Patent number: 8250134
    Abstract: The simultaneous processing of requests under multiple user identifiers is facilitated. The requests are processed by user servers, in which a user server has an association with a particular user. A user server has a static identity associated therewith and is capable of processing a plurality of requests prior to terminating. The requests are dispatched to the appropriate user servers via a dispatcher server coupled to the user servers.
    Type: Grant
    Filed: December 27, 2006
    Date of Patent: August 21, 2012
    Assignee: International Business Machines Corporation
    Inventors: Patrick J. Callaghan, Tung-Sing Chong
  • Patent number: 8250152
    Abstract: Generally speaking, systems, methods and media for facilitating user-specified delivery options for e-mail messages are disclosed. Embodiments of the method may include receiving by an e-mail client an indication of contents of an e-mail message and a plurality of intended recipients of the e-mail message and generating the e-mail message based on the received indication. Embodiments may also include receiving an indication of user-specified delivery options for each intended recipient of the message, generating meta-data based on the user-specified delivery options, and adding an indication of the meta-data to the message, such as in the data area of the e-mail message. Embodiments may also include transmitting the e-mail message to a mail server.
    Type: Grant
    Filed: August 3, 2006
    Date of Patent: August 21, 2012
    Assignee: International Business Machines Corporation
    Inventors: Omar Cardona, Ricardo N. Olivieri
  • Patent number: D666354
    Type: Grant
    Filed: February 15, 2012
    Date of Patent: August 28, 2012
    Assignee: Schonbek Worldwide Lighting Inc.
    Inventor: Todd Bracher
  • Patent number: D666438
    Type: Grant
    Filed: April 29, 2011
    Date of Patent: September 4, 2012
    Assignee: Magnussen International Corp.
    Inventors: Nathan David Cressman, Matthew Hurley
  • Patent number: D667158
    Type: Grant
    Filed: March 21, 2012
    Date of Patent: September 11, 2012
    Assignee: Boyd Lighting Fixture Company
    Inventors: Andrew G. Fisher, Jeffry H. Weisman