Patents Assigned to Advanced Cardiovascular Systems
  • Stent Fixture Having Rounded Support Structures and Method for Use Thereof
    Publication number: 20100221409
    Abstract: A stent fixture for supporting a stent during the application of a coating substance is provided.
    Type: Application
    Filed: May 12, 2010
    Publication date: September 2, 2010
    Applicant: Advanced Cardiovascular Systems, Inc.
    Inventors: Nathan Harold, Antonio Garcia, Andrew Tochterman
  • Biobeneficial polyamide/polyethylene glycol polymers for use with drug eluting stents
    Patent number: 7786249
    Abstract: This disclosure covers polymers, which are useful in medical device applications. The polymers comprise at least two different blocks, at least one L1 block with the formula and at least one L2 block with the formula Medical devices comprising these polymers, mixtures of these polymers with therapeutic agents, and methods of making these polymers and mixtures are within the scope of this disclosure. Some of these medical devices are implantable within a mammalian body, such as in a body lumen.
    Type: Grant
    Filed: September 9, 2008
    Date of Patent: August 31, 2010
    Assignee: Advanced Cardiovascular Systems, Inc.
    Inventor: Stephen D. Pacetti
  • Methods of providing antioxidants to a drug containing product
    Patent number: 7785647
    Abstract: A method of providing an antioxidant to a medical device is described.
    Type: Grant
    Filed: July 25, 2005
    Date of Patent: August 31, 2010
    Assignee: Advanced Cardiovascular Systems, Inc.
    Inventor: Ni Ding
  • Method and system of controlled temperature mixing and molding of polymers with active agents for implantable medical devices
    Patent number: 7785512
    Abstract: A method and system for making a composition for use in manufacturing an implantable medical device, such as a drug-eluting and/or delivery stent, is described. The method includes introducing a polymer, active agent, and a solvent into a mixing apparatus such as an extruder. The polymer, active agent, and solvent may be mixed in the apparatus to form a homogeneous or substantially homogeneous polymer mixture. The method may further include controlling a temperature of the polymer mixture in at least a portion of the apparatus. In an embodiment, the polymer mixture may be used as a coating for an implantable medical device, or fabricating an implantable medical device. The invention also includes a composition formed by the method described above.
    Type: Grant
    Filed: May 25, 2004
    Date of Patent: August 31, 2010
    Assignee: Advanced Cardiovascular Systems, Inc.
    Inventor: Jaya Pathak
  • Catheter with optical fiber sensor
    Patent number: 7783338
    Abstract: An apparatus and method to perform therapeutic treatment and diagnosis of a patient's vasculature through the use of an intravascular device having an optical fiber disposed therein. In an embodiment, the apparatus includes an intravascular device to perform a therapeutic treatment and at least one optical fiber disposed through the intravascular device. The optical fiber is configured to provide diagnostic information before, during, and after the therapeutic treatment. In an embodiment, diagnostic information includes vessel and blood characteristics such as hemodynamic characteristics, hematological parameters related to blood and blood components, and thermal parameters of the vasculature.
    Type: Grant
    Filed: January 9, 2008
    Date of Patent: August 24, 2010
    Assignee: Advanced Cardiovascular Systems, Inc.
    Inventors: Robert Ainsworth, Deborah Kilpatrick, Jeong S. Lee, Bridget A. Hurley, Jeffrey T. Ellis
  • Intravascular device and system
    Patent number: 7780694
    Abstract: A device for use in capturing or collecting debris found in blood vessels or other body lumens. The devices can be fabricated from a tube and include longitudinally and circumferentially extending members. The device can further embody structure that provides enhanced radial opening and angular resistance to collapse and structure for absorbing or modifying forces applied thereto by an operator.
    Type: Grant
    Filed: October 6, 2003
    Date of Patent: August 24, 2010
    Assignee: Advanced CArdiovascular Systems, Inc.
    Inventors: Olin Palmer, Christopher T. Shen, Robert LaDuca, Larry Voss, Saypin Phonthalasa, John E. Papp, Stephen A. Morales, Coeta K. Peloquin, Charles R. Peterson, Anuja H. Patel
  • Biologically absorbable coatings for implantable devices based on polyesters and methods for fabricating the same
    Patent number: 7776991
    Abstract: The disclosure contains a medical article comprising a polymer containing polyesters and, optionally, agents for use with medical articles and methods of fabricating the same are disclosed. The medical article generally comprises an implantable substrate having a coating, and the coating contains a polymer comprising a polymeric product of a reaction comprising a polyol and a polycarboxylic acid.
    Type: Grant
    Filed: June 19, 2009
    Date of Patent: August 17, 2010
    Assignee: Advanced Cardiovascular Systems, Inc.
    Inventors: Stephen D. Pacetti, Yiwen Tang
  • Stent mandrel fixture and method for reducing coating defects
    Patent number: 7776381
    Abstract: A stent mandrel fixture for supporting a stent during the application of a coating substance is provided.
    Type: Grant
    Filed: September 26, 2002
    Date of Patent: August 17, 2010
    Assignee: Advanced Cardiovascular Systems, Inc.
    Inventors: Fuh-Wei Tang, Syed F A Hossainy, Dorie M. Happ, Ty Hu
  • Stent coating apparatus and method
    Patent number: 7775178
    Abstract: An apparatus and method for coating abluminal surface of a stent is described. The apparatus includes a stent support, a coating device, and an imaging system. The coating device includes a solution reservoir and transducer assembly. The transducer assembly includes a plurality of transducers and a controller. Each transducer is used to generate focused acoustic waves in the coating substance in the reservoir. A controller is communicated to an image system to enable the transducers to generate droplets on demand and at the predetermined ejection points on the surface of the coating substance to coat the stent. A method for coating a stent includes stent mounting, stent movement, and droplet excitation.
    Type: Grant
    Filed: May 26, 2006
    Date of Patent: August 17, 2010
    Assignee: Advanced Cardiovascular Systems, Inc.
    Inventor: Yung Ming Chen
  • Biocompatible coating for implantable medical devices
    Patent number: 7776926
    Abstract: A random or a block copolymer which includes at least one biologically compatible structural moiety and at least one biologically active moiety is disclosed. The random or block copolymer can be used for fabricating a coating for an implantable medical device such as a stent.
    Type: Grant
    Filed: December 11, 2002
    Date of Patent: August 17, 2010
    Assignee: Advanced Cardiovascular Systems, Inc.
    Inventors: Charles D. Claude, Syed F. A. Hossainy, Eugene T. Michal
  • Balloon catheter having a flexible distal end
    Patent number: 7771449
    Abstract: A catheter having an elongated shaft with a proximal end, a distal end, and at least one lumen, and a distal portion of the shaft being at least in part within an outer sheath having a wedge-shaped distal end. In one embodiment, the outer sheath around the distal end of the shaft is the distal skirt section of the balloon. In an alternative embodiment, the outer sheath is a sleeve member having at least a portion located distal to the distal end of the balloon.
    Type: Grant
    Filed: October 24, 2006
    Date of Patent: August 10, 2010
    Assignee: Advanced Cardiovascular Systems, Inc.
    Inventors: Jacky G. Duchamp, Misty Lynn Gervais, Teresita Baerga
  • Coating abluminal surfaces of stents and other implantable medical devices
    Patent number: 7770536
    Abstract: A sleeve is positioned over a radially-expandable rod assembly and a stent is positioned over the sleeve. A mandrel is inserted into the rod assembly to thereby press the sleeve against the inner surface of the stent and expand the stent. A coating (such as a solvent, a polymer and/or a therapeutic substance) is then applied to the outer (abluminal) surfaces of the stent, by spraying, for example. The sleeve advantageously prevents the coating material from being applied to inner (luminal) surfaces of the stent and also allows the coating material to be efficiently applied to the abluminal surfaces.
    Type: Grant
    Filed: April 15, 2008
    Date of Patent: August 10, 2010
    Assignee: Advanced Cardiovascular Systems, Inc.
    Inventors: Yung Ming Chen, Jeff H. Smith, Celenia Gutierrez
  • Biobeneficial polyamide/polyethylene glycol polymers for use with drug eluting stents
    Patent number: 7772359
    Abstract: This disclosure provides a method device and a method of forming the medical device. The medical device comprises a coating comprising a polymer. The polymer comprises at least two different blocks, at least one L1 block with the formula and at least one L2 block with the formula Medical devices comprising these polymers, mixtures of these polymers with therapeutic agents, and methods of making these polymers and mixtures are within the scope of this disclosure.
    Type: Grant
    Filed: September 9, 2008
    Date of Patent: August 10, 2010
    Assignee: Advanced Cardiovascular Systems, Inc.
    Inventor: Stephen D. Pacetti
  • Apparatus and process for electrolytic removal of material from a medical device
    Patent number: 7771581
    Abstract: An apparatus and process is disclosed for the electrolytic removal of metal from a device, such as a medical device. More particularly, the apparatus of the invention includes a mandrel having slots or openings therein to expose portions of a metallic device, such as a stent, to an electrolytic solution to remove metal from the exposed portion.
    Type: Grant
    Filed: May 17, 2005
    Date of Patent: August 10, 2010
    Assignee: Advanced Cardiovascular Systems, Inc.
    Inventors: Joseph R. Callol, Karim Said Osman, Napoleon L. Caliguiran, Rommel C. Lumauig
  • Coating for Implantable Devices and a Method of Forming the Same
    Publication number: 20100198340
    Abstract: Coatings for implantable devices or endoluminal prosthesis, such as stents, are provided, including a method of forming the coatings. The coatings can be used for the delivery of an active ingredient or a combination of active ingredients.
    Type: Application
    Filed: March 12, 2010
    Publication date: August 5, 2010
    Applicant: Advanced Cardiovascular Systems, Inc.
    Inventors: Syed F.A. Hossainy, Stephen D. Pacetti, Keith E. Fong, Vinayak Bhat, Deborra Sanders Millare, Judy A. Guruwaiya, Daryush Mirzaee, Evgenia Mandrusov
  • Coating for Implantable Devices and a Method of Forming the Same
    Publication number: 20100198339
    Abstract: Coatings for implantable devices or endoluminal prosthesis, such as stents, are provided, including a method of forming the coatings. The coatings can be used for the delivery of an active ingredient or a combination of active ingredients.
    Type: Application
    Filed: March 12, 2010
    Publication date: August 5, 2010
    Applicant: Advanced Cardiovascular Systems, Inc.
    Inventors: Syed F.A. Hossainy, Stephen D. Pacetti, Keith E. Fong, Vinayak Bhat, Deborra Sanders Millare, Judy A. Guruwaiya, Daryush Mirzaee, Evgenia Mandrusov
  • COATING FOR IMPLANTABLE DEVICES AND A METHOD OF FORMING THE SAME
    Publication number: 20100198342
    Abstract: Coatings for implantable devices or endoluminal prosthesis, such as stents, are provided, including a method of forming the coatings. The coatings can be used for the delivery of an active ingredient or a combination of active ingredients.
    Type: Application
    Filed: March 12, 2010
    Publication date: August 5, 2010
    Applicant: Advanced Cardiovascular Systems, Inc.
    Inventors: Syed F.A. Hossainy, Stephen D. Pacetti, Keith E. Fong, Vinayak Bhat, Deborra Sanders Millare, Judy A. Guruwaiya, Daryush Mirzaee, Evgenia Mandrusov
  • COATING FOR IMPLANTABLE DEVICES AND A METHOD OF FORMING THE SAME
    Publication number: 20100198341
    Abstract: Coatings for implantable devices or endoluminal prosthesis, such as stents, are provided, including a method of forming the coatings. The coatings can be used for the delivery of an active ingredient or a combination of active ingredients.
    Type: Application
    Filed: March 12, 2010
    Publication date: August 5, 2010
    Applicant: Advanced Cardiovascular Systems, Inc.
    Inventors: Syed F.A. Hossainy, Stephen D. Pacetti, Keith E. Fong, Vinayak Bhat, Deborra Sanders Millare, Judy A. Guruwaiya, Daryush Mirzaee, Evgenia Mandrusov
  • COATING FOR IMPLANTABLE DEVICES AND A METHOD OF FORMING THE SAME
    Publication number: 20100198343
    Abstract: Coatings for implantable devices or endoluminal prosthesis, such as stents, are provided, including a method of forming the coatings. The coatings can be used for the delivery of an active ingredient or a combination of active ingredients.
    Type: Application
    Filed: March 12, 2010
    Publication date: August 5, 2010
    Applicant: Advanced Cardiovascular Systems, Inc.
    Inventors: Syed F.A. Hossainy, Stephen D. Pacetti, Keith E. Fong, Vinayak Bhat, Deborra Sanders Millare, Judy A. Guruwaiya, Daryush Mirzaee, Evgenia Mandrusov
  • Polymers of fluorinated monomers and hydrophilic monomers
    Patent number: 7766884
    Abstract: A polymer blend that contains a polymer of fluorinated monomers and another biocompatible polymer. The polymer blend can form a coating on a medical device. The medical device can be used for treat, prevent or ameliorate a medical condition.
    Type: Grant
    Filed: May 25, 2007
    Date of Patent: August 3, 2010
    Assignee: Advanced Cardiovascular Systems, Inc.
    Inventor: Stephen Dirk Pacetti