Abstract: An illumination device provides light to a flowing gaseous sample. The device includes a structure including a cavity configured to have a microplasma disposed therein. The cavity substantially encircles a cross-section of a channel that is configured to pass the flowing gaseous sample therethrough. The cavity is defined in part by an interior wall of the structure separating the cavity from the channel. The interior wall includes at least one orifice passing therethrough configured to provide to the flowing gaseous sample light generated by the microplasma. At least one electrode is configured to supply energy to the microplasma within the cavity.

Abstract: A dissolution test apparatus includes a vessel support member, weight sensors, a movable component, a media transport cannula, a pump, and an electronic controller. The vessel support member receives vessels. A weight sensor is located at each vessel site. Each weight sensor contacts a vessel and transmits a measurement signal indicative of the weight of the vessel and any contents therein. The movable component moves the media transport cannula toward a vessel site. The pump establishes media flow between the media transport cannula and the selected vessel. The controller communicates with the weight sensors and may also communicate with the pump. Based on the measurement signals received from the weight sensors, the electronic controller may calculate the volume of media in a given vessel. The electronic controller may also control media flows to or from the vessels by transmitting control signals to the pump assembly.

Abstract: An ion source a first ionizer comprising: an electrospray needle comprising a tip; and a conduit disposed annularly about the needle and configured to pass an inert gas in proximity of the tip to nebulize a fluid emerging from the tip, the nebulized fluid comprising analytes and a mobile phase. The ion source comprises a capillary in tandem with the first ionizer and configured to receive the droplets; a heater configured to heat the capillary to a temperature at which mobile phase vaporizes; and a second ionizer in tandem with the capillary and configured to receive the vaporized mobile phase and the analytes. A method is also described.

Abstract: A number of RF receivers are connected in a network. The network is used to transmit communications, data, or both to and from the RF receivers and to synchronize the RF receivers to a common time. Digitized RF data is time-stamped and stored in memory. A trigger circuit in one or more RF receivers determines whether a trigger criterion or criteria has been met. When a trigger criterion or criteria has been met, some or all of the RF receivers in the network transmit select digitized RF data to a central processing device. The central processing device processes the select digitized data to detect if a signal is present.

Abstract: A device includes: a plurality of sampling phase detectors, each receiving a sampling signal and a VCO output signal and in response thereto outputting a beat signal representing a frequency and phase difference between the VCO output signal and the sampling signal; a frequency/phase detector receiving a reference signal and a combined beat signal produced by combining the beat signals, and in response thereto producing an error signal representing a phase difference between the reference signal and the combined beat signal; a loop integrator receiving the error signal and in response thereto producing the VCO control signal; a power detector detecting a power level of the combined beat signal; and at least one offset voltage generator adjusting a value of a bias voltage in response to the detected power level of the combined beat signal, and applying the adjusted bias voltage to one of the sampling phase detectors.

Abstract: An image processor includes an optical processor and a microwave processor. The optical processor is configured to extract optical image information from optical image data provided by a sensor, the optical image data representing an optical image of an object. The microwave image processor is configured to produce microwave image data representing a microwave image of the object in response to the extracted optical image information and microwave measurements provided by a microwave imager based on illuminating the object with microwave radiation.

Abstract: A system and method are provided which coordinate the actions of a plurality of devices via scheduling occurrence of the actions based on synchronized local clocks of the devices. Thus, a plurality of devices are communicatively coupled via a communication network, and the devices have their local clocks synchronized to a high degree of precision, using IEEE 1588, NTP, or some other technique for synchronizing their local clocks. “Time bombs” can be scheduled on the devices to coordinate the occurrence of actions between the devices in accordance with the detonation times set for the respective time bombs. In certain embodiments, not only the detonation time, but also the respective action to be triggered upon detonation is programmable for each device. The time bombs implemented on the various devices can be used to coordinate the operations of the various devices with a high degree of temporal precision.

Abstract: The invention relates to compositions, methods, and kits for nucleic acid replication, including polymerase chain reaction (PCR) and mutagenesis reactions. A buffer composition is provided which allows higher concentrations of DNA polymerase to be used, resulting in greater yield of amplified product and faster reaction kinetics.

Abstract: A valve for use in high-performance liquid chromatography has a spherical seat and a ball that, when it abuts against the seat, constrains a fluid from flowing through the valve and is capable of moving axially in order to allow the fluid to flow through the valve. The spherical seat has beveled outer faces in order that a force acting on the valve along the axial direction will generate a force acting on the ball. The inclination of the beveled outer face is such that a force acting on the ball counteracts a force exerted on the spherical seat by the ball and essentially compensates it.

Abstract: The subject invention relates to compositions comprising an enzyme mixture which comprises a first enzyme and a second enzyme, where the first enzyme comprises a DNA polymerization activity and the second enzyme comprises an 3?-5? exonuclease activity and a reduced DNA polymerization activity. The invention also relates to the above compositions in kit format and methods for high fidelity DNA synthesis using the subject compositions of the invention.

Abstract: A microfluidic connection comprising a carrier element having a microfluidic channel fixed between a feeding element and a backplate. The feeding element comprises a channel adopted for feeding a fluid into the microfluidic channel of the carrier element. The backplate comprises a recess arranged opposing the feeding element and comprising an elastic thrust piece.

Abstract: Methods, user interfaces, systems and computer readable media for visualizing data to facilitate analysis of the data. Mass data values are provided for a sample having been separated into portions according to a first characteristic of the sample, the slices having been processed to provide the mass data values of members of the sample occurring in the portions. A plot of the mass data values is displayed on a first axis versus the portions on a second axis of the plot. A mass data value of a member may be selected on the plot, and all mass data values occurring in the portion in which the selected mass data value is located are displayed using first visual indicators that are visibly distinct from visual indicators used to display data values occurring outside of the portion in which the selected data value is located.

Abstract: A polymer modified porous substrate for solid phase extraction or chromatography, comprising a porous substrate and a polymeric monolith formed thereon, wherein the polymeric monolith comprises C5-10 monocyclic or bicyclic aryl or heteroaryl, optionally substituted with -L-Qp-Rq; where q is 0-3, p is 0-5, Q is —NRC(O)—, —C(O)NR—, —OC(O)NR—, —OC(O)R—, —NRC(O)O—, —NRC(O)NR—, —NCO, —CHOHCHOH—, CH2OCHCH2O—, —(CH2CH2O)s—, —(CH2CH2CH2O)s—, —C(O)—, —C(O)O—, —CH2C(O)CH2—, —S—, —SS—, —CHOH—, —O—, —SO—, —SO2—, —SO3—, —OSO3, —SO2NR—, —NRq—, and —NRq+—, —CN, —NC, —CHOCH—, —NHC(NH)NH—, —NO2, —NO, —OPO3—, —OH; and R is hydrogen, C5-10 monocyclic or bicyclic aryl or heteroaryl, C1-12 branched, unbranched, or cyclic hydrocarbyl; L is a bond or a C1-12 branched, unbranched, or cyclic hydrocarbyl. Methods of preparing and using the polymer modified porous substrates are disclosed.

Abstract: Methods for linearly amplifying mRNA to produce antisense RNA are provided. In the subject methods, mRNA is converted to double-stranded cDNA using a promoter-primer having a poly-dT primer site linked to a promoter sequence so that the resulting double-stranded cDNA is recognized by an RNA polymerase. The resultant double-stranded cDNA is then transcribed into antisense RNA in the presence of a reverse transcriptase that is rendered incapable of RNA-dependent DNA polymerase activity during this transcription step. The subject methods find use a variety of different applications in which the preparation of linearly amplified amounts of antisense RNA is desired. Also provided are kits for practicing the subject methods.

Abstract: A measurement displacement system and method are described. The measurement displacement system comprises a sensor head configured to transmit input optical beams and to receive measurement beams. The system comprises a transmission grating configured to diffract the input optical beams into sub-beams comprising more than one diffraction order. The transmission grating is adapted move in a direction. The measurement displacement system comprises a reflective element configured to diffract the sub-beams from the transmission grating and to return the sub-beams to the transmission grating. The reflective element is substantially stationary relative to the sensor head and the transmission grating selectively recombines the sub-beams to form the measurement beams and returns the measurement beams to the sensor head.

Abstract: A method for determining input tones required to produce a desired output includes the step of extracting a linearization of a spectral map representing a device under test (DUT) that i) is under drive of a large signal having one or more fundamental frequencies with associated amplitudes and phases, and ii) produces an approximation of a desired output having at least one unwanted spectral component. The method includes the further step of using an inverse of the extracted linearization to determine the input tones required to produce the desired output under a given load condition.

Abstract: Pluggable communication modules, e.g. SFP, XFP, XENPAK, on a service provider's packet switched network will include network monitoring capability, e.g. Intelligent Pluggable Modules. The Intelligent Pluggable Modules are configured to detect emergency calls. When an emergency call is detected, the module notifies a software application of the detected call, including the Media Access Controller (MAC) address of the caller. The application then queries the network equipment, typically the Digital Subscriber Line Access Multiplexer for the ingress port of the MAC address using a protocol such as SNMP. Upon receipt, the service provider's customer database is then queried for the physical port location corresponding to the MAC address. The management station then sends the physical location into the existing 911 system.

Abstract: A data conversion system acquires samples of low frequency signal components of an applied analog signal at a first data conversion rate and samples of high frequency signal components of the applied analog signal at a second data conversion rate that is higher than the first data conversion rate. The data conversion system applies a first correction filter to the acquired samples of the low frequency signal components to provide a first filtered signal and applies a second correction filter to the acquired samples of the high frequency signal components to provide a second filtered signal. The data conversion system interpolates the first filtered signal to provide an interpolated signal, and sums the interpolated signal with the second filtered signal to provide an output signal.

Abstract: Assay chambers that include a form-in-place gasket between a substrate and a cover, and methods of forming such assay chambers, are described. The assay chambers may further be associated with an analysis site for analyzing a sample solution contained within the assay chamber.

Abstract: The mass spectrometer includes a mass analyzer having a pair of planar electrode structures. The electrode structures are disposed opposite one another, parallel to one another, and axially offset from one another, and are structured to generate, in response to a common pattern of voltages applied to them, a cylindrically-symmetric, annular electric field surrounding a cylindrical central region. The electric field includes an annular axially focusing lens region surrounding the central region, and an annular mirror region surrounding the lens region. Ions injected tangentially in the central region towards the electric field reach an ion detector after executing a number of ellipse-like orbits, which enables a long flight path to be accommodated within a small evacuated space.