Patents Assigned to Alcon
  • Use of certain isoquinolinesulfonyl compounds for the treatment of glaucoma and ocular ischemia
    Patent number: 6403590
    Abstract: Isoquinolinesulfonyl compounds are used in ophthalmic compositions to treat glaucoma or other ischemic-borne ocular disorders such as retinopathies or optic neuropathies. These compounds vasodilate ocular blood vessels, lower IOP and prevent or reduce the progression of visual field loss.
    Type: Grant
    Filed: July 31, 2001
    Date of Patent: June 11, 2002
    Assignee: Alcon Laboratories, Inc.
    Inventors: Mark R. Hellberg, Michael A. Kapin, Louis M. Desantis, Jr.
  • Intraocular lens injector cartridge
    Patent number: 6398789
    Abstract: An intraocular lens injector cartridge having a heat retention additive for helping the cartridge retain heat once the cartridge is warmed. Such additives can include an biocompatible material having high heat retention, for example, powdered gold.
    Type: Grant
    Filed: October 19, 2000
    Date of Patent: June 4, 2002
    Assignee: Alcon Universal, Ltd.
    Inventor: Thomas G. Capetan
  • Use of inhibitors of gag synthesis for the treatment of corneal haze
    Patent number: 6399107
    Abstract: This invention relates to the compositions and methods for the treatment of corneal haze. The compositions and methods are particularly directed to the use of GAG synthesis inhibitors in the treatment of corneal haze.
    Type: Grant
    Filed: June 20, 2001
    Date of Patent: June 4, 2002
    Assignee: Alcon Laboratories, Inc.
    Inventors: Timothy L. Kessler, Jon C. Nixon, Karen C. David, Gustav Graff
  • Liquefracture handpiece tip
    Patent number: 6398759
    Abstract: A surgical handpiece having two coaxially mounted tubes or channels mounted to a body. The first tube is used for aspiration and is smaller in diameter than the second tube so as to create an annular passage between the first and second tube. The annular gap communicates with a pumping chamber formed between two electrodes. The pumping chamber works by boiling a small volume of the surgical fluid. As the fluid boils, it expands rapidly, thereby propelling the liquid downstream of the pumping chamber out of the annular gap. The distal end of the annular gap is sealed by frictionally fitting together the distal ends of the first and second tube. One or more grooves formed in either the first or second tubes allow fluid being propelled down the annular gap to escape. A stop may be provided against which the escaping fluid impinges such as by crimping the second tube near the distal end of the second tube.
    Type: Grant
    Filed: October 17, 2000
    Date of Patent: June 4, 2002
    Assignee: Alcon Manufacturing, Ltd.
    Inventors: Glenn Sussman, Donald M. Cohen
  • Methods for treating ocular diseases
    Patent number: 6399058
    Abstract: Methods, for lowering intraocular pressure by implanting in the anterior chamber encapsulated cells which secrete an intraocular pressure lowering substance.
    Type: Grant
    Filed: March 3, 2000
    Date of Patent: June 4, 2002
    Assignee: Alcon Manufacturing, Ltd.
    Inventor: Iok-Hou Pang
  • Compositions containing a benzamide disulfide derivative for treating allergic diseases
    Publication number: 20020065281
    Abstract: Methods and compositions for preventing or treating allergic diseases of the eye, nose, skin, ear, gastrointestinal tract, airways or lung and preventing or treating manifestations of systemic mastocytosis are disclosed. The compositions contain a mast cell stabilizing disulfide derivative as an active ingredient.
    Type: Application
    Filed: April 25, 2001
    Publication date: May 30, 2002
    Applicant: Alcon Universal Ltd.
    Inventors: Steven T. Miller, Mark R. Hellberg, Zixia Feng
  • Anterior chamber phakic lens
    Patent number: 6395028
    Abstract: An anterior chamber phakic lens made from an elastomeric, foldable, highly biocompatible material. The lens has a generally circular optic and integrally formed plate-style haptics, the haptics containing an opening into which project a pair of pincer arms. The pincer arms are sized and shaped so as to pull away from each other when the lens is folded, and are draw back toward each other when the folded lens is released and allowed to return to its unfolded state. Such movement allows the pincers to gather a small section of the iris so as to hold the lens in place.
    Type: Grant
    Filed: July 18, 2001
    Date of Patent: May 28, 2002
    Assignee: Alcon Universal Ltd.
    Inventors: Son Trung Tran, Stephen J. Van Noy
  • Fogging method for a wavefront sensor
    Patent number: 6394605
    Abstract: An automated focusing method for a wavefront sensor that iteratively determines the best optics setting for the wavefront sensor by making objective measurements of the patient's focus without the need for subjective information from the patient.
    Type: Grant
    Filed: May 23, 2001
    Date of Patent: May 28, 2002
    Assignee: Alcon Universal Ltd.
    Inventors: John A. Campin, Gary P. Gray, George H. Pettit
  • Methods of treating ophthalmic, otic and nasal infections and attendant inflammation
    Patent number: 6395746
    Abstract: Methods of treating or preventing ophthalmic, otic, and nasal infections and attendant inflammation are described. The methods utilize ophthalmic, otic, and nasal compositions containing a new class of antibiotics (e.g. trovafloxacin). The compositions also contain one or more anti-inflammatory agents (e.g. dexamethasone). The compositions are utilized to treat ophthalmic, otic, and nasal conditions by topically applying the compositions to the affected tissues.
    Type: Grant
    Filed: September 22, 2000
    Date of Patent: May 28, 2002
    Assignee: Alcon Manufacturing, Ltd.
    Inventors: Gerald Cagle, Robert L. Abshire, David W. Stroman, John M. Yanni
  • Disulfide derivatives useful for treating allergic diseases
    Publication number: 20020058709
    Abstract: Novel disulfide derivatives useful for preventing or treating allergic diseases of the eye, nose, skin, ear, gastrointestinal tract, airways or lung and preventing or treating manifestations of systemic mastocytosis are disclosed. The disulfide derivatives act as mast cell stabilizers.
    Type: Application
    Filed: April 25, 2001
    Publication date: May 16, 2002
    Applicant: Alcon Universal Ltd.
    Inventors: Zixia Feng, Mark R. Hellberg, Steven T. Miller
  • Stannane synthesis of prostanoids
    Patent number: 6388128
    Abstract: The present invention is directed to novel methods of prostanoid synthesis. Specifically, the invention is directed to the addition of alpha chains to prostanoids using cis-alkenylstannane intermediates.
    Type: Grant
    Filed: March 23, 2001
    Date of Patent: May 14, 2002
    Assignee: Alcon Manufacturing, Ltd.
    Inventor: Raymond E. Conrow
  • Hydrophobically-bound, hydrophilic coating compositions for surgical implants
    Patent number: 6388035
    Abstract: Hydrophilic coatings for implants are disclosed. The coatings are hydrophobically bound to the implant, but are not covalently cross-linked or covalently anchored to the implant's surface.
    Type: Grant
    Filed: August 24, 2000
    Date of Patent: May 14, 2002
    Assignee: Alcon Universal Ltd.
    Inventor: Albert R. LeBoeuf
  • Method of treating neurodegenerative disorders of the retina and optic nerve head
    Publication number: 20020049255
    Abstract: The use of 3-benzolphenylacetic acids and derivatives, including nepafenac, to treat neurodegenerative retinal disorders is disclosed.
    Type: Application
    Filed: August 13, 2001
    Publication date: April 25, 2002
    Applicant: Alcon Universal Ltd.
    Inventors: Daniel A. Gamache, Gustav Graff, John M. Yanni, Michael A. Kapin
  • Upregulation of endogenous prostaglandins to lower intraocular pressure
    Patent number: 6376541
    Abstract: A method of lowering intraocular pressure (IOP) employs an upregulating agent that induces increased prostaglandin synthesis in the eye. The method of treatment entails administering to the eye of a mammal in need thereof a prostaglandin upregulating agent to increase endogenous prostaglandin synthesis and thereby effect a reduction in intraocular pressure. In a preferred embodiment the upregulating agent is IL-1.
    Type: Grant
    Filed: December 6, 1999
    Date of Patent: April 23, 2002
    Assignee: Alcon Manufacturing, Ltd.
    Inventors: Jon C. Nixon, Karen C. David
  • Ophthalmic anti-allergy compositions suitable for use with contact lenses
    Patent number: 6375973
    Abstract: Topically administrable anti-allergy compositions comprising olopatadine and a polymeric quaternary ammonium preservative are suitable for use by patients wearing contact lenses.
    Type: Grant
    Filed: January 24, 2001
    Date of Patent: April 23, 2002
    Assignee: Alcon Universal Ltd.
    Inventor: John M. Yanni
  • Aniline disulfide derivatives for treating allergic diseases
    Patent number: 6372802
    Abstract: Methods and compositions for preventing or treating allergic diseases of the eye, nose, skin, ear, gastrointestinal tract, airways or lung and preventing or treating manifestations of systemic mastocytosis are disclosed. The compositions contain a mast cell stabilizing disulfide derivative as an active ingredient.
    Type: Grant
    Filed: April 25, 2001
    Date of Patent: April 16, 2002
    Assignee: Alcon Universal Ltd.
    Inventors: Mark R. Hellberg, Zixia Feng, Steven T. Miller
  • Substituted tetrahydrofuran analogs of prostaglandins as ocular hypotensives
    Patent number: 6369102
    Abstract: Substituted tetrahydrofuran analogs of prostaglandins and methods of their use in treating glaucoma and ocular hypertension are disclosed.
    Type: Grant
    Filed: March 6, 2001
    Date of Patent: April 9, 2002
    Assignee: Alcon Manufacturing, Ltd.
    Inventor: Robert D. Selliah
  • Use of borate-polyol complexes in ophthalmic compositions
    Patent number: 6365636
    Abstract: Water-soluble borate-polyol complexes are useful as buffers and/or antimicrobials in aqueous ophthalmic compositions, including those containing polyvinyl alcohol. These compositions have greater antimicrobial activity than comparable compositions containing typical borate buffers and unexpectedly increase the antimicrobial efficacy of other antimicrobial agents when used in combination. In addition, use of the borate-polyol complexes avoids the incompatibility problem typically associated with the combination of borate buffer and polyvinyl alcohol; therefore, the compositions disclosed herein may also contain polyvinyl alcohol.
    Type: Grant
    Filed: June 20, 2000
    Date of Patent: April 2, 2002
    Assignee: Alcon Manufacturing, Ltd.
    Inventors: Masood Chowhan, Nissanke L. Dassanayake
  • Topical composition comprising ciprofloxacin and hydrocortisone
    Publication number: 20020037884
    Abstract: This invention is directed toward a topical composition comprising ciprofloxacin and hydrocortisone, where the composition contains a specific grade of polyvinyl alcohol as a viscosity augmenter. The specified grade of polyvinyl alcohol is 85-90% hydrolyzed polyvinyl alcohol.
    Type: Application
    Filed: July 16, 2001
    Publication date: March 28, 2002
    Applicant: Alcon Universal Ltd.
    Inventors: Onkar N. Singh, Haresh G. Bhagat, Bhagwati P. Kabra
  • Bottle
    Patent number: D456075
    Type: Grant
    Filed: February 26, 2001
    Date of Patent: April 23, 2002
    Assignee: Alcon Universal Ltd.
    Inventors: Don A. Clements, Donn D. Lobdell