Patents Assigned to Alcon
  • Upregulation of endogenous prostaglandins to lower intraocular pressure
    Patent number: 6376541
    Abstract: A method of lowering intraocular pressure (IOP) employs an upregulating agent that induces increased prostaglandin synthesis in the eye. The method of treatment entails administering to the eye of a mammal in need thereof a prostaglandin upregulating agent to increase endogenous prostaglandin synthesis and thereby effect a reduction in intraocular pressure. In a preferred embodiment the upregulating agent is IL-1.
    Type: Grant
    Filed: December 6, 1999
    Date of Patent: April 23, 2002
    Assignee: Alcon Manufacturing, Ltd.
    Inventors: Jon C. Nixon, Karen C. David
  • Ophthalmic anti-allergy compositions suitable for use with contact lenses
    Patent number: 6375973
    Abstract: Topically administrable anti-allergy compositions comprising olopatadine and a polymeric quaternary ammonium preservative are suitable for use by patients wearing contact lenses.
    Type: Grant
    Filed: January 24, 2001
    Date of Patent: April 23, 2002
    Assignee: Alcon Universal Ltd.
    Inventor: John M. Yanni
  • Aniline disulfide derivatives for treating allergic diseases
    Patent number: 6372802
    Abstract: Methods and compositions for preventing or treating allergic diseases of the eye, nose, skin, ear, gastrointestinal tract, airways or lung and preventing or treating manifestations of systemic mastocytosis are disclosed. The compositions contain a mast cell stabilizing disulfide derivative as an active ingredient.
    Type: Grant
    Filed: April 25, 2001
    Date of Patent: April 16, 2002
    Assignee: Alcon Universal Ltd.
    Inventors: Mark R. Hellberg, Zixia Feng, Steven T. Miller
  • Substituted tetrahydrofuran analogs of prostaglandins as ocular hypotensives
    Patent number: 6369102
    Abstract: Substituted tetrahydrofuran analogs of prostaglandins and methods of their use in treating glaucoma and ocular hypertension are disclosed.
    Type: Grant
    Filed: March 6, 2001
    Date of Patent: April 9, 2002
    Assignee: Alcon Manufacturing, Ltd.
    Inventor: Robert D. Selliah
  • Use of borate-polyol complexes in ophthalmic compositions
    Patent number: 6365636
    Abstract: Water-soluble borate-polyol complexes are useful as buffers and/or antimicrobials in aqueous ophthalmic compositions, including those containing polyvinyl alcohol. These compositions have greater antimicrobial activity than comparable compositions containing typical borate buffers and unexpectedly increase the antimicrobial efficacy of other antimicrobial agents when used in combination. In addition, use of the borate-polyol complexes avoids the incompatibility problem typically associated with the combination of borate buffer and polyvinyl alcohol; therefore, the compositions disclosed herein may also contain polyvinyl alcohol.
    Type: Grant
    Filed: June 20, 2000
    Date of Patent: April 2, 2002
    Assignee: Alcon Manufacturing, Ltd.
    Inventors: Masood Chowhan, Nissanke L. Dassanayake
  • Topical composition comprising ciprofloxacin and hydrocortisone
    Publication number: 20020037884
    Abstract: This invention is directed toward a topical composition comprising ciprofloxacin and hydrocortisone, where the composition contains a specific grade of polyvinyl alcohol as a viscosity augmenter. The specified grade of polyvinyl alcohol is 85-90% hydrolyzed polyvinyl alcohol.
    Type: Application
    Filed: July 16, 2001
    Publication date: March 28, 2002
    Applicant: Alcon Universal Ltd.
    Inventors: Onkar N. Singh, Haresh G. Bhagat, Bhagwati P. Kabra
  • Pharmaceutical suspension compositions lacking a polymeric suspending agent
    Publication number: 20020037877
    Abstract: Stable aqueous pharmaceutical suspension compositions containing lecithin as a stabilizing additive and lacking a polymeric suspending agent are disclosed.
    Type: Application
    Filed: July 16, 2001
    Publication date: March 28, 2002
    Applicant: Alcon Universal Ltd.
    Inventor: Onkar N. Singh
  • Process for manufacturing compositions containinig ciprofloxacin and hydrocortisone
    Publication number: 20020037883
    Abstract: This invention is directed toward a method of preparing a topical composition comprising ciprofloxacin and hydrocortisone. The method involves dispersing hydrocortisone with lecithin for greater than 45 minutes prior to combining hydrocortisone with the balance of the composition.
    Type: Application
    Filed: July 16, 2001
    Publication date: March 28, 2002
    Applicant: Alcon Universal Ltd.
    Inventor: Onkar N. Singh
  • Method of treating angiogenesis-related disorders
    Publication number: 20020037929
    Abstract: The use of 3-benzolphenylacetic acids and derivatives, including nepafenac, to treat angiogenesis-related disorders, including ophthalmic angiogenesis-related disorders such as diabetic retinopathy and exudative macular degeneration, is disclosed.
    Type: Application
    Filed: August 13, 2001
    Publication date: March 28, 2002
    Applicant: Alcon Universal Ltd.
    Inventors: Michael A. Kapin, David P. Bingaman, Daniel A. Gamache, Gustav Graff, John M. Yanni
  • Pharmaceutical compositions containing tobramycin and xanthan gum
    Publication number: 20020035088
    Abstract: Topically administrable aqueous solution compositions containing tobramycin and xanthan gum are disclosed. The solution compositions contain a buffering agent and a pH-adjusting agent in an amount sufficient to achieve a pH above 7.8 in order to minimize or avoid compatibility problems between tobramycin and xanthan gum.
    Type: Application
    Filed: July 11, 2001
    Publication date: March 21, 2002
    Applicant: Alcon Universal Ltd.
    Inventors: Nuria Carreras Perdiguer, Jose Alberto Vallet Mas, Gemma Torrella Cabello
  • Lamellar dissecting instrument
    Patent number: 6358262
    Abstract: A microsurgical instrument having a handle and a dissecting tip coupled to the handle is disclosed. The handle includes a cannula for transporting surgical fluid. The dissecting tip includes a blade for dissecting tissue and an aperture for delivering the fluid. The instrument may be used to more effectively create an intracorneal pocket for the implantation of an intracorneal optical lens.
    Type: Grant
    Filed: December 20, 1999
    Date of Patent: March 19, 2002
    Assignee: Alcon Universal Ltd.
    Inventors: Kwan Y. Chan, Gregory S. Milios, David E. Booth, Dyson W. Hickingbotham
  • Lamellar dissecting instrument
    Patent number: 6358261
    Abstract: A microsurgical instrument that includes a handle and a dissecting tip coupled to the handle is disclosed. The tip includes a blade having a generally elliptical three-dimensional geometry. The blade may include an edge having a first arc and an opposing second arc. When the instrument is used to form an intracorneal pocket for the implantation of an intracorneal optical lens, the curvature of the first arc allows the edge to dissect a first blind spot of the pocket, and the curvature of the second arc allows the edge to dissect a second blind spot of the pocket. The blade may also be formed with a first depression in its top surface and a second depression in its bottom surface. When the instrument is used to form an intracorneal pocket, the depressions reduce the drag on, and corresponding trauma to, stromal tissue.
    Type: Grant
    Filed: November 5, 1999
    Date of Patent: March 19, 2002
    Assignee: Alcon Universal Ltd.
    Inventors: Kwan Y. Chan, Gregory S. Milios, David E. Booth, Dyson W. Hickingbotham
  • Alkyl trypsin compositions and methods of use in contact lens cleaning and disinfecting systems
    Patent number: 6358897
    Abstract: Improved stability, liquid enzyme compositions containing an alkylated trypsin and methods involving the combined use of these compositions with an aqueous composition are disclosed for the cleaning or simultaneous cleaning and disinfecting of contact lens. Methods for a daily use regimen are also disclosed.
    Type: Grant
    Filed: September 1, 1998
    Date of Patent: March 19, 2002
    Assignee: Alcon Laboratories, Inc.
    Inventors: Bor-Shyue Hong, Bahram Asgharian, Ronald P. Quintana
  • Topical suspension formulations containing ciprofloxacin and dexamethasone
    Patent number: 6359016
    Abstract: Suspension formulations containing dexamethasone and ciprofloxacin are disclosed. The formulations contain a nonionic polymer, a nonionic surfactant and an ionic tonicity agent, but are physically stable and easily re-suspended. The formulations are intended for topical application to the eye, ear or nose.
    Type: Grant
    Filed: May 25, 2001
    Date of Patent: March 19, 2002
    Assignee: Alcon Universal Ltd.
    Inventors: Onkar N. Singh, Haresh G. Bhagat
  • Switchable tackiness coating compositions for ophthalmic implants
    Publication number: 20020028330
    Abstract: The application of switchable tackiness coating compositions to ophthalmic implants provides the benefits of body temperature tackiness without the disadvantages of room temperature tackiness.
    Type: Application
    Filed: August 24, 2001
    Publication date: March 7, 2002
    Applicant: Alcon Universal Ltd.
    Inventors: Anilbhai S. Patel, Douglas C. Schlueter, Mutlu Karakelle
  • Compositions containing hydroxyeicosatetraenoic acid derivatives and methods of use in treating dry eye disorders
    Patent number: 6353022
    Abstract: Compositions containing one or more HETE derivative(s) and an effective concentration of ethanol and methods of use for treating dry eye are disclosed.
    Type: Grant
    Filed: October 23, 2000
    Date of Patent: March 5, 2002
    Assignee: Alcon Universal Ltd.
    Inventors: L. Wayne Schneider, Daniel A. Gamache, Lori K. Weimer, Timothy L. Kessler, Zhongyou Wei, Terri Pasquine, John M. Yanni, Haresh G. Bhagat
  • 11-halo prostaglandins for the treatment of glaucoma or ocular hypertension
    Patent number: 6353000
    Abstract: A method of treating glaucoma or ocular hypertension in a patient, which comprises administering to the patient a pharmaceutically effective amount of a compound of formula I:
    Type: Grant
    Filed: June 2, 1999
    Date of Patent: March 5, 2002
    Assignee: Alcon Laboratories, Inc.
    Inventors: Verney L. Sallee, Mark R. Hellberg, Peter G. Klimko, Paul W. Zinke
  • Phospholipids of hydroxyeicosatetraenoic acid-like derivatives and methods of use
    Patent number: 6353032
    Abstract: Phospholipid-HETE derivatives, compositions and methods of use are disclosed. The compounds are particularly useful for treating dry eye.
    Type: Grant
    Filed: October 23, 2000
    Date of Patent: March 5, 2002
    Assignee: Alcon Universal Ltd.
    Inventors: Gustav Graff, Peter G. Klimko
  • Pharmaceutical compositions containing tobramycin and xanthan gum
    Patent number: 6352978
    Abstract: Topically administrable aqueous solution compositions containing tobramycin and xanthan gum are disclosed. The solution compositions contain a buffering agent and a pH-adjusting agent in an amount sufficient to achieve a pH above 7.8 in order to minimize or avoid compatibility problems between tobramycin and xanthan gum.
    Type: Grant
    Filed: July 11, 2001
    Date of Patent: March 5, 2002
    Assignee: Alcon Universal Ltd.
    Inventors: Nuria Carreras Perdiguer, Jose Alberto Vallet Mas, Gemma Torrella Cabello
  • Bottle
    Patent number: D456075
    Type: Grant
    Filed: February 26, 2001
    Date of Patent: April 23, 2002
    Assignee: Alcon Universal Ltd.
    Inventors: Don A. Clements, Donn D. Lobdell