Abstract: The invention relates to the diagnostic and therapeutic uses of a miRNA molecule, an equivalent or a source thereof in a disease and condition associated with melanoma or a disease or a condition associated with activated BRAF pathway.
Type:
Application
Filed:
January 4, 2013
Publication date:
May 2, 2013
Applicants:
Koninklijke Nederlandse Akademie van Wetenschappen, InteRNA Technologies B.V.
Inventors:
InteRNA Technologies B.V., Koninklijke Nederlandse Akademie van Wetensch
Abstract: A voltage sampling RF receiver in which an impedance control circuit controls the input impedance, by using a mixer stage which generates a feedback voltage, which is coupled to the RF input by a feedback resistor. A biasing arrangement can be used to adjust the feedback path so that local oscillator leakage signals are suppressed.
Abstract: The present invention relates to a Lactuca sativa seed designated 79-190 RZ or 79-107 RZ, which exhibits a combination of traits including resistance to downy mildew (Bremia lactucae Regel.) races Bl:1 to Bl:28, currant-lettuce aphid (Nasonovia ribisnigri) biotype Nr:0, as well as an extraordinary high number of red-colored, elongated leaves of substantially equal size. The present invention also relates to a Lactuca sativa plant produced by growing the 79-190 RZ or 79-107 RZ seed. The invention further relates to methods for producing the lettuce cultivar, represented by lettuce variety 79-190 RZ or 79-107 RZ.
Type:
Application
Filed:
December 12, 2012
Publication date:
May 2, 2013
Applicant:
RIJK ZWAAN ZAADTEELT EN ZAADHANDEL B.V.
Abstract: The present invention provides herbicide-tolerant plants. The present invention also provides methods for controlling the growth of weeds by applying an herbicide to which herbicide-tolerant plants of the invention are tolerant. Plants of the invention may express an acetyl-Coenzyme A carboxylase enzyme that is tolerant to the action of acetyl-Coenzyme A carboxylase enzyme inhibitors.
Type:
Application
Filed:
September 1, 2010
Publication date:
May 2, 2013
Applicant:
BASF AGROCHEMICAL PRODUCTS, B.V,
Inventors:
Scots L. Mankin, Haiping Hong, Leon Neuteboom, Sherry R. Whitt, Dale R. Carlson, Ulrich Schöfl, Allan R. Wenck
Abstract: A poly(aryl ether sulfone) comprises units of formula (I): wherein Ar1 is a divalent C6-C15 aromatic group, Ar2 is a divalent C6-C15 aromatic group, Ar3 is a divalent C6-C15 aromatic group, and n is greater than 1; and a terminal group of formula (II) derived from a monofunctional phenoxide wherein is X is a hydrogen atom or an organic substituent having from 1 to 20 carbon atoms; wherein the poly(aryl ether sulfone) has a hydroxyl group content greater than 0 and less than 50 parts per million (ppm), based on the poly(aryl ether sulfone) weight, a glass transition temperature of 180 to 290° C., a weight average molecular weight of 20,000 to 100,000, a halogen content of greater than 0 and less than 3000 ppm based on the poly(aryl ether sulfone) weight. The poly(aryl ether sulfone) is free of methoxy groups.
Type:
Application
Filed:
October 31, 2011
Publication date:
May 2, 2013
Applicant:
SABIC INNOVATIVE PLASTICS IP B.V.
Inventors:
Eric Lee Lutz, William Hoy Heath, Roy Ray Odle, Thomas Link Guggenheim
Abstract: Antibodies which block binding of hPD-1 to hPD-L1 or hPD-L2 and their variable region sequences are disclosed. A method of increasing the activity (or reducing downmodulation) of an immune cell through the PD-1 pathway is also disclosed.
Abstract: A persistent connection is used for real-time or near real-time data transfer from a push platform on a network to a mobile station. To establish and maintain the persistent connection between the mobile station and push platform on the network, various protocols are defined over a packet connection between the mobile station and push platform. The real-time or near real-time data is pushed or sent by the push platform to the mobile station, as the data becomes available from a data source. In particular, heartbeat messages are used to determine whether or not the persistent connection is alive and available for real-time or near real-time data transfer. When the persistent connection is lost, the mobile station uses a retry connection scheme based on the number of connection attempts made by the mobile station for establishing a new persistent connection to the push platform.
Abstract: Exterior mirror unit for a motor vehicle comprising a mirror base for attachment to the motor vehicle and a mirror support for attachment of a mirror element, wherein the minor support is merely manually adjustable relative to the minor base, further comprising a coupling element for coupling of the mirror support with the minor base, wherein the coupling element is designed to pull the minor support towards the mirror base.
Abstract: A connector comprises a base, a gate, and a locking mechanism. The base forms an opening. The gate is slidably operatively connected to the base and spans the opening. The locking member has an engaging position and a releasing position. The engaging position secures the gate to the base, and the releasing position allows the gate to be moved relative to the base.
Abstract: A product that comprises a mounting hole or a preform for the mounting hole and a radio frequency identification transponder for wireless identification, said transponder comprising at least an integrated circuit and wiring, wherein the wiring of the transponder at least partly encircles the mounting hole or the preform, is disclosed. The product may be configured to break when the product is ripped between the mounting hole and an edge of the product. Furthermore, the product may operate in two modes depending on whether or not an electrically conductive object is penetrating the mounting hole, and may be configured to be suspended in connection with an electrically conductive hanger by using the mounting hole. In addition, a method to produce such a product is disclosed.
Abstract: A natural language call router forwards an incoming call from a caller to an appropriate destination. The call router has a speech recognition mechanism responsive to words spoken by a caller for producing recognized text corresponding to the spoken words. A robust parsing mechanism is responsive to the recognized text for detecting a class of words in the recognized text. The class is defined as a group of words having a common attribute. An interpreting mechanism is responsive to the detected class for determining the appropriate destination for routing the call.
Abstract: A canister style surface cleaning apparatus comprises a wheeled based having a front end and a cleaning mount, the cleaning mount adapted to receive a surface cleaning attachment that comprises a first flexible hose; a portable cleaning unit removably mounted on the wheeled base and comprising a suction motor and at least one cyclonic separation stage having an associated material collection chamber which is sealed when the portable cleaning unit is removed from the wheeled base; and, a fluid flow path extending from the cleaning mount to a clean air exit of the surface cleaning apparatus.
Abstract: A display driving system for an electrowetting display device having at least one display element, the display driving system comprising a driver stage for the display element, the driver stage providing a display voltage to be applied to the display element in response to a data signal representing an image to be displayed, the driver stage including a variable source providing a variable voltage in dependence on the data signal, the display driving system including an offset source providing an offset voltage, the display voltage being the sum of the offset voltage and the variable voltage.
Type:
Application
Filed:
December 18, 2012
Publication date:
May 2, 2013
Applicant:
SAMSUNG LCD NETHERLANDS R & D CENTER B.V.
Inventor:
Samsung LCD Netherlands R & D Center B.V.
Abstract: The present invention relates to Lactuca sativa seed designated 79-99 RZ, which exhibits resistance to downy mildew (Bremia lactucae Regel.) races Bl:1 to Bl:28, lettuce mosaic virus (LMV) and currant-lettuce aphid (Nasonovia ribisnigri) and which has deeply red, deeply-incised, nicely-filled leaves. The present invention also relates to a Lactuca sativa plant produced by growing the 79-99 RZ seed. The invention further relates to methods for producing the lettuce cultivar, represented by lettuce variety 79-99 RZ.
Type:
Application
Filed:
November 1, 2012
Publication date:
May 2, 2013
Applicant:
RIJK ZWANN ZAADTEELT EN ZAADHANDEL B.V.
Abstract: A valve 28 is positioned in the upper portion of the interior space of the bellows 10. A flow of low pressure air is induced inside the bellows when the valve elements 40 move away from the air inlet openings 38. When high pressure air is moved into the central portion of the valve housing 30, the valve elements 40 tend to move radially outwardly to block the air passages 38 and 42, thereby terminating the suction applied to the bellows.
Type:
Application
Filed:
November 2, 2011
Publication date:
May 2, 2013
Applicant:
AMF Automation Technologies, LLC, d/b/a AMF Baker Systems
Inventors:
Roland Lomerson, JR., Michael W. Norton
Abstract: A lithographic apparatus arranged to transfer a pattern from a patterning device onto a substrate, the lithographic apparatus including a substrate table constructed to hold a substrate and a gripper arranged to position the substrate on the substrate table. The gripper includes a vacuum clamp arranged to clamp the substrate at a top side thereof. The vacuum clamp may be arranged to clamp at least part of a circumferential outer zone of the substrate top surface. There is also provided a substrate handling method including positioning the substrate using a gripper on a substrate table of a lithographic apparatus, the method including clamping the substrate at a top side thereof using a vacuum clamp of the gripper.
Type:
Application
Filed:
October 24, 2012
Publication date:
May 2, 2013
Applicant:
ASML NETHERLANDS B.V.
Inventors:
Raymond Wilhelmus Louis LAFARRE, Hubert Marie Segers, Theodorus Petrus Maria Cadee, Yang-Shan Huang, Christiaan Louis Valentin
Abstract: Safe bus devices use a safety protocol in order to transmit safe data encapsulated in an industrial Ethernet message via an Ethernet-based field bus. However, this restricts the safe bus device to a certain combination of safety protocol and industrial Ethernet protocol. In order to be able to use a safe bus device 12, 14, 151 more flexibly, it is provided that, to transmit the safety-oriented data, the industrial Ethernet protocol uses the session layer 5 and/or presentation layer 6 of the safety protocol, which is independent of the industrial Ethernet protocol, instead of the session layer 5 and/or presentation layer 6 which is implemented in the industrial Ethernet protocol, whereby such a bus device 12, 14, 151 becomes independent of the industrial Ethernet protocol.
Abstract: A spin torque oscillator device having a magnetic free layer with a magnetic anisotropy that has a component that is oriented perpendicular to a direction of an applied magnetic field. The spin torque oscillator device includes a magnetic reference layer, a magnetic free layer and a non-magnetic layer sandwiched there-between. A component of the magnetic anisotropy of the free layer can be oriented perpendicular to a magnetization of the reference layer, and this orientation relative to the magnetization of the reference layer can be either in lieu of or in addition to its orientation relative to the applied magnetic field. The magnetic anisotropy cants the magnetization of the free layer which would otherwise be oriented antiparallel with the magnetization of the reference layer. The magnetic anisotropy in the free layer improves performance of the spin torque sensor by reducing noise.
Abstract: The invention relates to ring-annulated dihydropyrrolo[2,1-a]isoquinoline compounds according to general Formula I or a pharmaceutically acceptable salt thereof. The compounds can be used for the treatment of infertility.
Type:
Grant
Filed:
July 27, 2010
Date of Patent:
April 30, 2013
Assignee:
Merck Sharp & Dohme B.V.
Inventors:
Cornelis Marius Timmers, Hubert Jan Jozef Loozen, Herman Thijs Stock
Abstract: Storage architecture for bit patterned media uses both erase band and shingled magnetic recording. A hard disk drive may comprise a disk having bit patterned media with a plurality of data tracks arrayed in architecture pages having at least one of erase band mode (EBM), shingled mode (SM) and unallocated space. An actuator has a head for writing data to the data tracks of the bit patterned media. A control system monitors, reallocates and reconfigures the architecture pages from EBM, SM or unallocated space to a different one of EBM, SM or unallocated space to enhance performance of the hard disk drive.