Abstract: The invention relates to stabilized liquid fungicide-containing formulations based on fatty acid amides as solvents, to a process for production thereof, to a method of controlling phytopathogenic fungi in crop protection, and to the use thereof as crop protection agents.

Abstract: The invention relates to 17-hydroxy-17-pentafluoroethyl-estra-4,9(10)-dien-11-aryl derivatives of Formula I with progesterone antagonizing action and method of production thereof, use thereof for the treatment and/or prophylaxis of diseases and use thereof for the production of medicinal products for the treatment and/or prophylaxis of diseases, in particular of fibroids of the uterus (myomas, uterine leiomyoma), endometriosis, heavy menstrual bleeds, meningiomas, hormone-dependent breast cancers and complaints associated with the menopause or for fertility control and emergency contraception.

Abstract: The present invention relates to immunomodulator compositions and methods of use as well as methods of making. The immunomodulator compositions comprise immunostimulatory plasmids, or DNA sequence, capable of eliciting an immune response in a recipient subject. Further, the immunostimulatory plasmids, or DNA sequence, do not contain antibiotic resistance coding sequence to help reduce the potential of horizontal transfer of antibiotic resistance in a population.

Abstract: The present application relates to novel substituted imidazo[1,2-a]pyrazine carboxamides of general formula (I) to processes for their preparation, to their use, alone or in combinations, for the treatment and/or prophylaxis of diseases, and to their use for producing medicaments for the treatment and/or prophylaxis of diseases, in particular for the treatment and/or prophylaxis of cardiovascular disorders.

Abstract: A description is given of herbicidal compositions which comprise the active ingredients isoxaflutole and diflufenican. These herbicidal compositions are particularly suitable for use against weed plants in crops of useful plants.

Abstract: The present invention describes a novel method for preparing 4-cyanopiperidine hydrochloride.

Abstract: The instant disclosure provides an ability to use an array of data inputs to enter a network and thereby provide a realtime improvable database. The present invention is novel in its ability to maximize the customer's interface with a pest control system, thus allowing for maximum efficiency for current and future designs as well as a high level of compatibility with ancillary regulatory, financial and planning type functions.

Abstract: The invention relates inter alia to compounds of the general formula (I) in which the A1-A4, T, n, W, Q, R1 and B1-B4 radicals are each as defined in the description. Also described are processes for preparing the compounds of the formula (I). The inventive compounds are especially suitable for controlling insects, arachnids and nematodes in agriculture, and ectoparasites in veterinary medicine.

Abstract: An inserter for an intrauterine system includes a handle. The handle has a longitudinal opening at its first end, the opening having a longitudinal axis parallel to the longitudinal axis of the inserter, a first end and a second end, a movable slider arranged in the longitudinal opening and having a first end and a second end. The inserter also includes a movable plunger and an insertion tube arranged around the plunger having a first end and a second end, with its second end attached to the slider. The handle further includes a lock for reversibly locking the intrauterine system in relation to the plunger via a removal string of the intrauterine system, the lock being attached to the plunger and being controllable at least by a part or an extension of the slider and/or of the insertion tube or of the handle.

Abstract: The invention relates to a method for producing a security and/or valuable document containing a polymer layer composite or consisting thereof, said polymer layer composite being formed from a polymer layer partial composite and a polymer cover layer and the polymer layer partial composite and/or the polymer cover layer containing a laser sensitive component, consisting of the followings steps: A) first personalized information is applied to the polymer layer partial composite by means of an inkjet printing method as a colored inkjet printed layer, B) the polymer cover layer is applied to the inkjet printed layer and is joined to the polymer layer partial composite by thermal lamination, and C) second personalized information is inscribed into the polymer layer composite of the security and/or valuable document, obtained in step B), by means of laser engraving. The invention also relates to a security and/or valuable document that can be produced according to said method.

Abstract: This patent document relates to antibodies, antigen-binding antibody fragments (Fabs), and other protein scaffolds, directed against human antithrombin ? complexed with heparin and/or heparin-like structure (AT?H). These AT?H binding proteins can block the anti-coagulant activity of AT? to induce coagulation. Therapeutic uses of these antibodies and binders are described herein as are methods of panning and screening specific antibodies.

Abstract: The present invention relates to benzimidazol-2-amines of general formula (I) in which R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, R11 and R12 are as defined herein, to methods of preparing said compounds, to intermediate compounds useful for preparing said compounds, to pharmaceutical compositions and combinations comprising said compounds and to the use of said compounds for manufacturing a pharmaceutical composition for the treatment or prophylaxis of a disease, in particular of neoplasms, as a sole agent or in combination with other active ingredients.

Abstract: The present invention relates to a new class of high relaxivity extracellular gadolinium chelate complexes, to methods of preparing said compounds, and to the use of said compounds as MRI contrast agents.

Abstract: A method for protecting a pressure transducer from fluid pressure damage using a pressure isolation mechanism is disclosed. The method includes associating the pressure transducer with an isolation port of the pressure isolation mechanism, placing a pressurizing device for delivering fluid under pressure in fluid connection with an inlet port of the pressure isolation mechanism, and actuating the pressurizing device to cause fluid flow in the inlet port such that a free floating, fluid flow responsive valve member positioned in an internal cavity of the pressure isolation mechanism engages a seal seat therein to attain a closed position, preventing fluid flow between the inlet port and the isolation port and thus prevent overpressure in the isolation port. Hemodynamic pressure signals read with the pressure transducer may be transmitted at least in part through a body of the valve member, or a portion thereof, when in the closed position.

Abstract: The present application relates to novel bicyclic compounds, to their use for controlling animal pests and to processes and intermediates for their preparation.

Abstract: The present invention relates to benzimidazol-2-amines of general formula (I) in which R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, R11 and R12 are as defined herein, to methods of preparing said compounds, to intermediate compounds useful for preparing said compounds, to pharmaceutical compositions and combinations comprising said compounds and to the use of said compounds for manufacturing a pharmaceutical composition for the treatment or prophylaxis of a disease, in particular of neoplasms, as a sole agent or in combination with other active ingredients.

Abstract: The invention relates to substituted pyridobenzazepine and pyridobenzazocine derivatives and to processes for preparation thereof, and also to the use thereof for production of medicaments for treatment and/or prophylaxis of diseases, especially of cardiovascular disorders, preferably thrombotic or thromboembolic disorders, and oedemas, and also ophthalmic disorders.

Abstract: Isolated monoclonal antibodies that bind human tissue factor pathway inhibitor (TFPI) and the isolated nucleic acid molecules encoding them are provided. Pharmaceutical compositions comprising the anti-TFPI monoclonal antibodies and methods of treating deficiencies or defects in coagulation by administration of the antibodies are also provided. Methods of producing the antibodies are also provided.

Abstract: The present invention relates to substituted N-(phenyl-heteroaryl)-3-acetylamino-benzamides and N-[3-(acetylamino)phenyl]-phenyl-heteroaryl-carboxamides of general formula (I) as described and defined herein, to methods of preparing said compounds, to intermediate compounds useful for preparing said compounds, to pharmaceutical compositions and combinations comprising said compounds and to the use of said compounds for manufacturing a pharmaceutical composition for the treatment or prophylaxis of a disease such as cancer, wherein i.a.: LA represents an optionally substituted methylene or ethylene group; LB represents —N(H)—C(?O)— or —C(?O)—N(H)—; R1 represents an optionally substituted 5- to 8-membered heterocycloalkyl, 4- to 10-membered heterocycloalkenyl, aryl, heteroaryl or —N(R7)(Ci-C6-alkyl) group; R2 represents an optionally substituted 5- or 6-membered heteroaryl group; R3 represents an optionally substituted phenyl group.

Abstract: Isolated monoclonal antibodies that bind human tissue factor pathway inhibitor (TFPI) are provided. Isolated nucleic acid molecules encoding monoclonal antibodies that bind TFPI are also contemplated. Pharmaceutical compositions comprising the anti-TFPI monoclonal antibodies and methods of treating deficiencies or defects in coagulation by administration of the antibodies are also provided. Methods of producing the antibodies are also provided.