Patents Assigned to Corixa
  • Compositions and methods for therapy and diagnosis of ovarian cancer
    Patent number: 6488931
    Abstract: Compositions and methods for the therapy of cancer, such as ovarian cancer, are disclosed. Compositions may comprise one or more ovarian carcinoma proteins, immunogenic portions thereof, polynucleotides that encode such portions or antibodies or immune system cells specific for such proteins. Such compositions may be used, for example, for the prevention and treatment of diseases such as ovarian cancer. Methods are further provided for identifying tumor antigens that are secreted from ovarian carcinomas and/or other tumors.
    Type: Grant
    Filed: June 23, 1999
    Date of Patent: December 3, 2002
    Assignee: Corixa Corporation
    Inventors: Jennifer L. Mitcham, Tony N. Frudakis, Gordon E. King
  • Compositions and methods for the therapy and diagnosis of colon cancer
    Publication number: 20020177552
    Abstract: Compositions and methods for the therapy and diagnosis of cancer, such as colon cancer, are disclosed. Compositions may comprise one or more colon tumor proteins, immunogenic portions thereof, or polynucleotides that encode such portions. Alternatively, a therapeutic composition may comprise an antigen presenting cell that expresses a colon tumor protein, or a T cell that is specific for cells expressing such a protein. Such compositions may be used, for example, for the prevention and treatment of diseases such as colon cancer. Diagnostic methods based on detecting a colon tumor protein, or mRNA encoding such a protein, in a sample are also provided.
    Type: Application
    Filed: June 8, 2001
    Publication date: November 28, 2002
    Applicant: Corixa Corporation
    Inventors: Yuqiu Jiang, Susan L. Harlocker, Heather Secrist
  • Compositions and methods for the therapy and diagnosis of lung cancer
    Publication number: 20020172952
    Abstract: Compositions and methods for the therapy and diagnosis of cancer, particularly lung cancer, are disclosed. Illustrative compositions comprise one or more lung tumor polypeptides, immunogenic portions thereof, polynucleotides that encode such polypeptides, antigen presenting cell that expresses such polypeptides, and T cells that are specific for cells expressing such polypeptides. The disclosed compositions are useful, for example, in the diagnosis, prevention and/or treatment of diseases, particularly lung cancer.
    Type: Application
    Filed: July 10, 2001
    Publication date: November 21, 2002
    Applicant: Corixa Corporation
    Inventors: Robert A. Henderson, Tongtong Wang, Yoshihiro Watanabe, Jeffrey C. Johnson, Marc W. Retter, Margarita Durham, Darrick Carter, Gary R. Fanger, Thomas S. Vedvick, Chaitanya S. Bangur, Andria McNabb
  • Compounds and methods for therapy and diagnosis of lung cancer
    Patent number: 6482597
    Abstract: Compounds and methods for the treatment and diagnosis of lung cancer are provided. The inventive compounds include polypeptides containing at least a portion of a lung tumor protein. Vaccines and pharmaceutical compositions for immunotherapy of lung cancer comprising such polypeptides, or DNA molecules encoding such polypeptides, are also provided, together with DNA molecules for preparing the inventive polypeptides.
    Type: Grant
    Filed: January 10, 2000
    Date of Patent: November 19, 2002
    Assignee: Corixa Corporation
    Inventors: Tongtong Wang, Nancy A. Hosken, Michael D. Kalos, Gary R. Fanger, Liqun Fan
  • Compositions and methods for the therapy and diagnosis of colon cancer
    Publication number: 20020164345
    Abstract: Compositions and methods for the therapy and diagnosis of cancer, particularly colon cancer, are disclosed. Illustrative compositions comprise one or more colon tumor polypeptides, immunogenic portions thereof, polynucleotides that encode such polypeptides, antigen presenting cell that expresses such polypeptides, and T cells that are specific for cells expressing such polypeptides. The disclosed compositions are useful, for example, in the diagnosis, prevention and/or treatment of diseases, particularly colon cancer.
    Type: Application
    Filed: October 18, 2001
    Publication date: November 7, 2002
    Applicant: Corixa Corporation
    Inventor: Yuqiu Jiang
  • Compositions and methods for the therapy and diagnosis of colon cancer
    Publication number: 20020156011
    Abstract: Compositions and methods for the therapy and diagnosis of cancer, such as colon cancer, are disclosed. Compositions may comprise one or more colon tumor proteins, immunogenic portions thereof, or polynucleotides that encode such portions. Alternatively, a therapeutic composition may comprise an antigen presenting cell that expresses a colon tumor protein, or a T cell that is specific for cells expressing such a protein. Such compositions may be used, for example, for the prevention and treatment of diseases such as colon cancer. Diagnostic methods based on detecting a colon tumor protein, or mRNA encoding such a protein, in a sample are also provided.
    Type: Application
    Filed: January 15, 2002
    Publication date: October 24, 2002
    Applicant: Corixa Corporation
    Inventors: Yuqiu Jiang, Susan L. Harlocker, Heather Secrist, Aijun Wang, John A. Stolk
  • Ovarian tumor antigen and methods of use therefor
    Publication number: 20020155468
    Abstract: Compositions and methods for the therapy and diagnosis of cancer, such as ovarian cancer, are disclosed. Compositions may comprise HPP14, an immunogenic portion or variant thereof or a polynucleotide that encodes such a polypeptide. Alternatively, a therapeutic composition may comprise an antigen presenting cell that expresses HPP14 (or a portion or other variant thereof), or a T cell that is specific for cells expressing such a protein. Such compositions may be used, for example, for the prevention and treatment of diseases such as ovarian cancer. Diagnostic methods based on the detection of HPP14 expression are also provided.
    Type: Application
    Filed: December 7, 2001
    Publication date: October 24, 2002
    Applicant: Corixa Corporation
    Inventors: Davin C. Dillon, Susan Hand-Zimmermann, Steven P. Fling
  • Compositions and methods for therapy and diagnosis of ovarian cancer
    Patent number: 6468546
    Abstract: Compositions and methods for the therapy and diagnosis of cancer, such as ovarian cancer, are disclosed. Compositions may comprise one or more ovarian carcinoma proteins, immunogenic portions thereof, polynucleotides that encode such portions or antibodies or immune system cells specific for such proteins. Such compositions may be used, for example, for the prevention and treatment of diseases such as ovarian cancer. Methods are further provided for identifying tumor antigens that are secreted from ovarian carcinomas and/or other tumors. Polypeptides and polynucleotides as provided herein may further be used for the diagnosis and monitoring of ovarian cancer.
    Type: Grant
    Filed: September 24, 1999
    Date of Patent: October 22, 2002
    Assignee: Corixa Corporation
    Inventors: Jennifer L. Mitcham, Gordon E. King, Paul A. Algate
  • Compositions and methods for ovarian cancer therapy and diagnosis
    Patent number: 6468758
    Abstract: Compositions and methods for the therapy and diagnosis of cancer, such as ovarian cancer, are disclosed. Compositions may comprise one or more ovarian carcinoma proteins, immunogenic portions thereof, polynucleotides that encode such portions or antibodies or immune system cells specific for such proteins. Such compositions may be used, for example, for the prevention and treatment of diseases such as ovarian cancer. Methods are further provided for identifying tumor antigens that are secreted from ovarian carcinomas and/or other tumors. Polypeptides and polynucleotides as provided herein may further be used for the diagnosis and monitoring of ovarian cancer.
    Type: Grant
    Filed: September 16, 1999
    Date of Patent: October 22, 2002
    Assignee: Corixa Corporation
    Inventors: Darin R. Benson, Michael J. Lodes, Jennifer L. Mitcham, Gordon E. King
  • Immune mediators and related methods
    Publication number: 20020151707
    Abstract: Immune modulators, such as soluble, fused MHC heterodimers and soluble, fused MHC heterodimer:peptide complexes, are described. Related methods and peptides are also disclosed. In a preferred aspect, these mediators and methods are related to autoimmunity.
    Type: Application
    Filed: February 20, 2002
    Publication date: October 17, 2002
    Applicant: Corixa Corp.
    Inventors: Wayne Kindsvogel, Eva Pia Reich, Jane A. Gross, Shrinkant Deshpande, Paul O. Sheppard
  • Compositions and methods for the therapy and diagnosis of colon cancer
    Publication number: 20020150922
    Abstract: Compositions and methods for the therapy and diagnosis of cancer, particularly colon cancer, are disclosed. Illustrative compositions comprise one or more colon tumor polypeptides, immunogenic portions thereof, polynucleotides that encode such polypeptides, antigen presenting cell that expresses such polypeptides, and T cells that are specific for cells expressing such polypeptides. The disclosed compositions are useful, for example, in the diagnosis, prevention and/or treatment of diseases, particularly colon cancer.
    Type: Application
    Filed: November 16, 2001
    Publication date: October 17, 2002
    Applicant: Corixa Corporation
    Inventors: John A. Stolk, Jiangchun Xu, Ruth A. Chenault, Madeleine Joy Meagher
  • Compositions and methods for the therapy and diagnosis of breast cancer
    Publication number: 20020150581
    Abstract: Compositions and methods for the therapy and diagnosis of cancer, particularly breast cancer, are disclosed. Illustrative compositions comprise one or more breast tumor polypeptides, immunogenic portions thereof, polynucleotides that encode such polypeptides, antigen presenting cell that expresses such polypeptides, and T cells that are specific for cells expressing such polypeptides. The disclosed compositions are useful, for example, in the diagnosis, prevention and/or treatment of diseases, particularly breast cancer.
    Type: Application
    Filed: December 7, 2001
    Publication date: October 17, 2002
    Applicant: Corixa Corporation
    Inventors: Yuqiu Jiang, Davin C. Dillon, Jennifer L. Mitcham, Jiangchun Xu, Susan L. Harlocker, William T. Hepler, Robert A. Henderson, Gary R. Fanger, Thomas S. Vedvick, Patricia D. McNeill, Margarita Durham
  • Compositions and methods of their use in the treatment, prevention and diagnosis of tuberculosis
    Patent number: 6465633
    Abstract: The present invention relates to Mycobacterium antigens, optionally from a species such as M. tuberculosis, M. bovis, M. smegmatis, BCG, M. leprae, M. scrofulaceum, M avium-intracellulare, M. marinum, M. ulcerans, M. kansasii, M. xenopi, M. szulgai, M. fortuium, or M. chelonei. In particular, the invention relates to M. tuberculosis secretory polypeptides, polynucleotides that encode the polypeptides, and methods of using such compositions in the treatment, prevention and diagnosis of M. tuberculosis infection.
    Type: Grant
    Filed: December 23, 1999
    Date of Patent: October 15, 2002
    Assignee: Corixa Corporation
    Inventor: Yasir Skeiky
  • Compounds for immunotherapy of prostate cancer and methods for their use
    Patent number: 6465611
    Abstract: Compounds and methods for treating prostate cancer are provided. The inventive compounds include polypeptides containing at least a portion of a prostate tumor protein. Vaccines and pharmaceutical compositions for immunotherapy of prostate cancer comprising such polypeptides, or DNA molecules encoding such polypeptides, are also provided, together with DNA molecules for preparing the inventive polypeptides.
    Type: Grant
    Filed: January 15, 1999
    Date of Patent: October 15, 2002
    Assignee: Corixa Corporation
    Inventors: Jiangchun Xu, Davin C. Dillon, Jennifer Lynn Mitcham
  • Compositions and methods for the therapy and diagnosis of lung cancer
    Publication number: 20020147143
    Abstract: Compositions and methods for the therapy and diagnosis of cancer, particularly lung cancer, are disclosed. Illustrative compositions comprise one or more lung tumor polypeptides, immunogenic portions thereof, polynucleotides that encode such polypeptides, antigen presenting cell that expresses such polypeptides, and T cells that are specific for cells expressing such polypeptides. The disclosed compositions are useful, for example, in the diagnosis, prevention and/or treatment of diseases, particularly lung cancer.
    Type: Application
    Filed: June 28, 2001
    Publication date: October 10, 2002
    Applicant: Corixa Corporation
    Inventors: Tongtong Wang, Margarita Durham, Gary R. Fanger, Thomas S. Vedvick, Darrick Carter, Yoshihiro Watanabe, Robert A. Henderson, David W. Peckham, Neil Fanger
  • Compounds and methods for treatment and diagnosis of chlamydial infection
    Publication number: 20020146776
    Abstract: Compounds and methods for the diagnosis and treatment of Chlamydial infection are disclosed. The compounds provided include polypeptides that contain at least one antigenic portion of a Chlamydia antigen and DNA sequences encoding such polypeptides. Pharmaceutical compositions and vaccines comprising such polypeptides or DNA sequences are also provided, together with antibodies directed against such polypeptides. Diagnostic kits containing such polypeptides or DNA sequences and a suitable detection reagent may be used for the detection of Chlamydial infection in patients and in biological samples.
    Type: Application
    Filed: December 5, 2001
    Publication date: October 10, 2002
    Applicant: Corixa Corporation
    Inventors: Ajay Bhatia, Peter Probst
  • Compounds and methods for diagnosis of tuberculosis
    Patent number: 6458366
    Abstract: Compounds and methods for diagnosing tuberculosis are disclosed. The compounds provided include polypeptides that contain at least one antigenic portion of one or more M. tuberculosis proteins, and DNA sequences encoding such polypeptides. Diagnostic kits containing such polypeptides or DNA sequences and a suitable detection reagent may be used for the detection of M. tuberculosis infection in patients and biological samples. Antibodies directed against such polypeptides are also provided.
    Type: Grant
    Filed: May 5, 1998
    Date of Patent: October 1, 2002
    Assignee: Corixa Corporation
    Inventors: Steven G. Reed, Yasir A. W. Skeiky, Davin C. Dillon, Antonio Campos-Neto, Raymond Houghton, Thomas S. Vedvick, Daniel R. Twardzik, Michael J. Lodes, Ronald C. Hendrickson
  • Compositions and methods for the therapy and diagnosis of pancreatic cancer
    Publication number: 20020137911
    Abstract: Compositions and methods for the therapy and diagnosis of cancer, such as pancreatic cancer, are disclosed. Compositions may comprise one or more pancreatic tumor proteins, immunogenic portions thereof, or polynucleotides that encode such portions. Alternatively, a therapeutic composition may comprise an antigen presenting cell that expresses a pancreatic tumor protein, or a T cell that is specific for cells expressing such a protein. Such compositions may be used, for example, for the prevention and treatment of diseases such as pancreatic cancer. Diagnostic methods based on detecting a pancreatic tumor protein, or mRNA encoding such a protein, in a sample are also provided.
    Type: Application
    Filed: July 30, 2001
    Publication date: September 26, 2002
    Applicant: Corixa Corporation
    Inventors: Ruth A. Pyle, Jiangchun Xu
  • Compositions and methods for the therapy and diagnosis of colon cancer
    Publication number: 20020131971
    Abstract: Compositions and methods for the therapy and diagnosis of cancer, particularly colon cancer, are disclosed. Illustrative compositions comprise one or more colon tumor polypeptides, immunogenic portions thereof, polynucleotides that encode such polypeptides, antigen presenting cell that expresses such polypeptides, and T cells that are specific for cells expressing such polypeptides. The disclosed compositions are useful, for example, in the diagnosis, prevention and/or treatment of diseases, particularly colon cancer.
    Type: Application
    Filed: December 26, 2001
    Publication date: September 19, 2002
    Applicant: Corixa Corporation
    Inventors: Gordon E. King, Madeleine Joy Meagher, Jiangchun Xu, Heather Secrist
  • Compositions and methods for the therapy and diagnosis of ovarian cancer
    Publication number: 20020132237
    Abstract: Compositions and methods for the therapy and diagnosis of cancer, particularly ovarian cancer, are disclosed. Illustrative compositions comprise one or more ovarian tumor polypeptides, immunogenic portions thereof, polynucleotides that encode such polypeptides, antigen presenting cell that expresses such polypeptides, and T cells that are specific for cells expressing such polypeptides. The disclosed compositions are useful, for example, in the diagnosis, prevention and/or treatment of diseases, particularly ovarian cancer.
    Type: Application
    Filed: May 29, 2001
    Publication date: September 19, 2002
    Applicant: Corixa Corporation
    Inventors: Paul A. Algate, Robert Jones, Susan L. Harlocker