Abstract: Described herein are antibodies that target Leukemia Inhibitory Factor (LIF). Also described herein are uses of these antibodies for the treatment of cancer.
Type:
Grant
Filed:
December 18, 2017
Date of Patent:
July 19, 2022
Assignees:
MEDIMMUNE LIMITED, FUNDACIO PRIVADA INSTITUT D'INVESTIGACIO ONCOLOGIC, FUNDACIO PRIVADA INSTITUCIO CATALANA DE RECERCA I
Inventors:
Joan Seoane Suarez, Judit Anido Folgueira, Johan Fransson, Jean-Philippe Julien, Swetha Raman
Abstract: The present disclosure provides an image sensor and a method for manufacturing deep trench and through-silicon via of the image sensor, wherein: providing a pixel silicon wafer, performing a silicon wafer thinning on a second side of the pixel silicon wafer; forming a deep trench on the the second side of the pixel silicon wafer; filling the deep trench with organic material; coating photoresist on the second side of the pixel silicon wafer; etching the second side of the pixel silicon wafer to form a through-silicon via according to the through-silicon via pattern; depositing a dielectric protective layer on the surface of the deep trench and the surface of the through-silicon via; filling the deep trench with organic material; coating the photoresist on the second side of the pixel silicon wafer; etching the second side of the pixel silicon wafer to form a contact hole according to the contact hole pattern, depositing a barrier layer on the surface of the deep trench and the surface of the through-silicon v
Abstract: Embodiments of the present disclosure include methods, apparatuses, and systems for receiving feedback during transport. Embodiments include a transportation system comprising a tractor, a dolly attached to opposing ends of a first and second trailer, and a sensor feedback system. Sensor feedback system may include a tilt sensor system mounted on at least one of the dolly, the first trailer, and the second trailer, and a user feedback system mounted within the tractor. Tilt sensor system may measure tilt of at least one of the dolly, first and second trailers, and first and second containers attached to the first and second trailers, to obtain tilt information, and send tilt information to the user feedback system via a communication system. User feedback system may receive the tilt information and alert a driver of the tractor if the tilt information is above a predetermined level.
Abstract: The invention provides crystalline forms of biphenyl-2-ylcarbamic acid 1-(2-{[4-(4-carbamoylpiperidin-1-ylmethyl)benzoyl]methylamino}ethyl)piperidin-4-yl ester, and pharmaceutically acceptable solvates thereof. The crystalline form can be a freebase, or a salt such as a diphosphate, monosulfate or dioxalate salt. The invention also provides pharmaceutical compositions comprising these crystalline compounds or prepared using these compounds; processes and intermediates for preparing the crystalline compounds; and methods of using these compounds to treat a pulmonary disorder.
Abstract: A sintered material exhibiting the following chemical composition, as percentages by weight: iron oxide(s), expressed in the Fe2O3 form, ?85%, CaO: 0.1%-6%, SiO2: 0.1%-6%, 0.05% ?TiO2, 0?Al2O3, TiO2+Al2O3?3%, and constituents other than iron oxides, CaO, SiO2, TiO2 and Al2O3: ?5%. The CaO/SiO2 ratio by weight is between 0.2 and 7. The TiO2/CaO ratio by weight is between 0.2 and 1.5.
Type:
Grant
Filed:
April 19, 2017
Date of Patent:
July 19, 2022
Assignee:
SAINT-GOBAIN CENTRE DE RECHERCHES ET D'ETUDES EUROPEEN
Abstract: The present disclosure provides a support for household appliance and a household appliance, the support for household appliance comprises a hydraulic plate, which is fixed to the bottom of the household appliance; a sheath, which is fixedly connected with the hydraulic plate; a regulating support, which is arranged in the sheath and is axially movable relative to the sheath; an accommodation chamber, which is formed by the hydraulic plate, the sheath and the regulating support; and a flexible accommodation body, which accommodates a liquid medium and is arranged in the accommodation chamber. The flexible accommodation body extends and retracts to drive the regulating support to axially move in the sheath for leveling under the action of pressure. The hydraulic plate is locally embedded inside the sheath, thus, the overall height of the support for household appliance is reduced while the overall strength of the hydraulic plate is guaranteed.
Abstract: An intraoral flexible mouthpiece including: a hollow dome portion including a peripheral proximal edge. The hollow dome portion extends distally, and the hollow dome portion includes a central orifice located at the distal portion of the hollow dome portion. A peripheral flexible sheet flange attached along the dome portion peripheral proximal edge. A tube attached to the central orifice and extending distally therefrom. The peripheral flexible sheet flange is configured to be placed in the mouth between the teeth and gums on one side and the lips and cheeks on the other side, and the hollow dome portion is configured to protrude distally out of the mouth.
Abstract: The present invention relates to a connector (1) for a wiper blade, designed to be interposed between an adapter and a structural element of the wiper blade. The connector (1) extends longitudinally between a first longitudinal end (14) and a second longitudinal end (14). The connector (1) comprises at least one fixing block (22) configured such as mechanically to connect the connector (1) to the structural element of the wiper blade and a linking block (13) configured such as mechanically to connect the connector (1) to the adapter. The connector (1) comprises at least one skirt (23) that extends longitudinally from the fixing block (22). The skirt (23) comprises at least one rib (24) that extends between the fixing block (22) and one of the longitudinal ends (14).
Type:
Grant
Filed:
December 27, 2019
Date of Patent:
July 19, 2022
Assignee:
Valeo Systèmes d'Essuyage
Inventors:
Vincent Gaucher, Stéphane Houssat, Guillaume Mouleyre
Abstract: A system and a method for a security strap device including a strap; a lock, the lock comprising a locking mechanism; a fixed portion of the strap being secured inside the lock; a free end of the strap insertable into the lock to form a loop in the strap, the lock is configured to lock a portion of the strap to form the loop in the strap, wherein; the locking mechanism comprises a plurality of latches moveable between a locking position and an unlocking position; the plurality of latches engaging one or more locking slots within the lock when in the locking position to the lock the strap within the lock; and wherein the latches are all simultaneously biased toward the locked position and the latches are required to be simultaneously displaced to an unlocking position to unlock the strap.
Type:
Grant
Filed:
February 14, 2020
Date of Patent:
July 19, 2022
Assignee:
Logistics and Supply Chain MultiTech R&D Centre Limited
Inventors:
Chun Wai Lai, Kwong Man Pun, Yiu Man Chan
Abstract: An armrest assembly for a vehicle seat, the assembly comprising an armrest, a support, and an intermediate portion, the armrest being movable in translation along a vertical direction relative to the support, the assembly further comprising a locking device for the armrest comprising: a first part having toothed elements, and a second part capable of coming into contact with the toothed elements of the first part, and wherein the second part is movable between a locking position in which the second part is in contact with the toothed elements of the first part and an unlocking position allowing movement in translation along the vertical direction of the armrest.
Abstract: A vehicle seat that includes a support intended to be rigidly fixed to the frame of a vehicle, a seating portion, a backrest extending the rear end of the seating portion, and a connecting mechanism which connects the seating portion to the support. The connecting mechanism has a primary mechanism which allows forward tilting of the seating portion and backrest relative to the support between a rest position and a forward-tilted position. The seat includes a first motor able to tilt the seating portion from its rest position to its tilted position, and a control member for the first motor.
Abstract: A computer readable storage medium is presented, having computer readable program instructions thereon for causing a processor to carry out the steps of: sub-dividing a time slot into consecutive time intervals, the time slot belongs to multiple time slots allocated to a first node for transmitting to a second node using a wireless time-division duplex communication link between the first node and the second node, the second node transmitting during separate time slots allocated to said second node; and disrupting communication between said first node and said second node by transmitting, using a transmitter, respective interference signals during at least some of said time intervals, each of said interference signals being transmitted on one of said frequency bands, wherein for at least two of said time intervals said interference signals are transmitted on different frequency band.
Abstract: A powder formed of fused particles. More than 95% by number of the feed particles exhibiting a circularity of greater than or equal to 0.85. The powder contains more than 88% of a silicate of one or more elements chosen from Zr, Hf, Y, Ce, Sc, In, La, Gd, Nd, Sm, Dy, Er, Yb, Eu, Pr, Ho and Ta, less than 10% of a dopant, as percentage by weight based on the oxides. The powder has a median particle size D50 of less than 15 ?m, a 90 percentile particle size, D90, of less than 30 ?m, and a size dispersion index (D90-D10)/D10 of less than 2. The powder has a relative density of greater than 90%. The Dn percentiles of the powder are the particle sizes corresponding to the percentages, by number, of n %, on the cumulative distribution curve of the size of the particles of the powder. The particle sizes are classified in increasing order.
Type:
Grant
Filed:
January 31, 2019
Date of Patent:
July 19, 2022
Assignee:
SAINT-GOBAIN CENTRE DE RECHERCHES ET D'ETUDES EUROPEEN
Abstract: A vehicle seat comprising a seat back with a seat back frame, a seat cushion with a seat cushion frame and one first and second links. The first link is mounted pivoting relative to the seat cushion frame around a first transverse axis, and relative to a seat support around a second transverse axis. The second link is mounted pivoting relative to the seat cushion frame around a third transverse axis, and relative to a seat support around a fourth transverse axis. The first and second links are configured in order to allow lifting a rear part of the seat cushion frame relative to said seat support.
Abstract: A nanofiber based multi-layer filtration material suitable for use in providing air filtration to a user's respiratory system may be provided. as an air filtration garment and/or other air filterina devices such as a face mask, mask and garments or the like. The laminate includes a one or more fabric layer adjacent to one or more nanofiber layers.
Type:
Application
Filed:
July 19, 2021
Publication date:
July 14, 2022
Applicant:
L&C Protec, Inc. d/b/a Cocoon, Inc.
Inventors:
John Peter Lord, Crotty Leo, Vishal Bansal, Christopher Ferraro, Yit-Hong Tee
Abstract: The present invention relates to an ancillary laundry composition for use in laundering white fabrics, the ancillary laundry composition comprising: a. 0.001 to 5 wt. % fluorescer, b. 0.5 to 12 wt. % non-ionic surfactant; and c. Water.
Abstract: The present invention relates to an ancillary laundry composition comprising: a. Soil release polymer; b. 0.5 to 20 wt. % free perfume; c. 0.5-12 wt. % non-ionic surfactant; and d. Water.
Abstract: The invention relates to a method for detecting the rotary angle positions (?, ?) of rotating parts of a wiper motor, the wiper motor having a brushless electric motor as a first part which comprises a rotor rotating about a first axis of rotation and which drives a gear wheel as a second part which rotates about a second axis of rotation and which comprises a driven shaft, and the rotary angle positions (?, ?) of the two rotating parts being detected by means of two sensor devices each having a signal generating element and a sensor element for detecting a changing physical parameter of the signal generating element.
Type:
Application
Filed:
May 4, 2020
Publication date:
July 14, 2022
Applicant:
Valeo Systemes d'Essuyage
Inventors:
Matthias SCHOENDELING, Michael SCHAEUBLE, Joerg BUERKLE, Tobias GROENIG