Abstract: The present invention relates to a system (1) for cleaning an optical sensor (3), notably of a motor vehicle, comprising: —an element (5) for spraying a cleaning liquid, —a tank (7) of cleaning liquid fluidically connected to the element (5) for spraying cleaning liquid, —a pump (9) configured to pump the cleaning liquid from the tank (7) to the element (5) for spraying the cleaning liquid, the system (1) also comprising a containment wall (11) for the cleaning liquid, which is movable between a retracted position in which the containment wall is configured to be positioned outside the field of view of the optical sensor (3) and a cleaning position in which the containment wall (11) is configured to be positioned in front of the optical sensor (3) so as to define a collection vessel (13) for the cleaning liquid, and in that it comprises an evacuation pipe (15) for the cleaning liquid that is connected both to the collection vessel (13) in the cleaning position and to the tank (7) of cleaning liquid.

Abstract: A pyranoglucose-substituted pyrazole compound, used as a pharmaceutical intermediate, having the structural formula represented by formula (9c). The present invention further relates to an intermediate compound represented by formula (10c) or a salt thereof. The present invention further relates to a preparation method of the aforementioned intermediate compound and a method of using the same to prepare an SGLT inhibitor. By means of the novel key intermediate, the preparation technique of an SGLT inhibitor is greatly simplified. In addition, because the intermediate can be precipitated in the form of a salt and is easy to purify, the purity of the SGLT inhibitor is significantly increased, compared with the original preparation pathway (crude product purity can reach 99% or more).

Abstract: Described herein are methods and devices for configuring a wireless device using audio data that is transmitted from a mobile device to the wireless device via a wired connection. For example, wireless configuration data may be sent from an audio port of the mobile device to an audio port of the wireless device while the mobile device and the wireless device are temporarily connected via an audio cable. According to an example method, a mobile device may determine wireless configuration data associated with a wireless local area network. The mobile device may then send the wireless configuration data to a wireless device via an audio port of the mobile device, such that the wireless device may be configured to access the wireless local area network.

Abstract: This microwave component (10) comprises a waveguide (12) comprising an upper layer, a lower layer, and a central layer (18) intermediate between the upper layer and the lower layer, said layers defining a zone (19) of propagation of an electromagnetic wave, the propagation zone (19) extending along a propagation axis, and comprising a cavity (32) bounded by the upper layer, the lower layer, and, laterally, by two opposite lateral edges (36) of the central layer (18). The waveguide (12) comprises at least one dielectric strip (28) placed in the propagation zone (19), the dielectric strip (28) being defined in one of the upper layer and the lower layer or being placed in the cavity (32) away from the lateral edges (36) of the cavity (32).

Abstract: A cap assembly for a refill capsule and associated refill system is disclosed. The cap assembly (200) comprises an inner wall (202) defining a conduit (203) through the cap assembly (200) and an outer wall (204) surrounding the inner wall to form a circumferential void between the inner and outer walls (202, 204). A connecting wall joins the inner and outer walls (202, 204). The cap assembly (200) further comprises a closure member (208) which is sealed to the inner wall (202) with a peripheral frangible connection (210). The frangible connection (210) is disposed between a first peripheral recess (222) formed between the inner wall (202) and the downstream side (208b) of the closure member (208), and a second peripheral recess (224) between the inner wall (202) and the upstream side (208b) of the closure member (208).

Abstract: The present invention relates to an oil-in-water-emulsified food product comprising: water, acetic acid, organic acids other than acetic acids, amino acids, phenolic compounds, and vegetable oil comprising 35 to 95 wt % C18:1 and 1 to 50 wt % C18:2 fatty acids, based on the weight of the vegetable oil.

Abstract: The present invention relates to novel crystalline forms of butanedioic acid 7-cyclopentyl-N,N-dimethyl-2-{[5-(piperazin-1-yl) pyridin-2-yl]amino}-7H-pyrrolo[2,3-d]pyrimidine-6-carboxamide of formula-la and process for preparation thereof. The present invention also relates to a process for the preparation of 7-cyclopentyl-N,N-dimethyl-2-{[5-(piperazin-1-yl)pyridin-2-yl]amino}-7H-pyrrolo[2,3-d] pyrimidine-6-carboxamide. Further, the present application also relates to acid addition salts of 7-cyclopentyl-N,N-dimethyl-2-{[5-(piperazin-1-yl)pyridin-2-yl]amino}-7H-pyrrolo[2,3-d] pyrimidine-6-carboxamide and process for the preparation thereof.

Abstract: A miniaturized, automated method for controlled printing of large arrays of nano- to femtoliter droplets by actively transporting mother droplets over hydrophilic-in-hydrophobic (“HIH”) micropatches. The technology uses single or double-plate devices where mother droplets can be actuated and HIH micropatches on one or both plates of the device where the droplets are printed. Due to the selective wettability of the hydrophilic micropatches in a hydrophobic matrix, large nano- to femtoliter droplet arrays are created when mother droplets are transported over the arrays. The parent droplets are moved by various droplet actuation principles. Also, a method using two plates placed one top another while being separated by a spacer. One plate is dedicated to confirming and guiding parent droplets by using hydrophilic patches in a hydrophobic matrix, while the other plate contains HIH arrays for printing of the droplets.

Abstract: A cap assembly for a refill capsule and associated refill system is disclosed. The cap assembly (200) comprises an inner wall (202) defining a conduit (203) through the cap assembly (200) and an outer wall (204) surrounding the inner wall to form a circumferential void between the inner and outer walls (202, 204). A connecting wall joins the inner and outer walls (202, 204). The cap assembly (200) further comprises a closure member (208) which is sealed to the inner wall (202) with a peripheral frangible connection (210). The frangible connection (210) is disposed between radially offset portions of the inner wall (202).

Abstract: There is disclosed a system for locating an object on a surface waveguide. The surface waveguide is made of one or more 1D wires and/or 2D waveguides comprising conductive elements arranged in patterns. Emitters with known positions can couple with receivers coupled with the surface waveguide. The position of receivers can be determined, for example by multilateration or signal strength indication. Conductive elements can be sprayed or sewed or otherwise deposited onto surfaces such as a ground floor, a sidewalk or a road lane. Described developments comprise the use of absorbers, protective layers, unidirectional emitters, contactless coupling, and various arrangements comprising frequency-selective layers, arrangements in lattices, trellis or anisotropic surfaces. Signal processing aspects and software embodiments are also described.

Abstract: A method for manufacturing a vehicle seat backrest comprises the steps of: providing first and second uprights of a backrest frame and a support member of an upper backrest adjustment device; positioning the first upright partly facing a first side face of the support member and the second upright partly facing a second side face of the support member; moving the first upright relative to the second upright along a transverse direction of the support member, in order to sandwich the support member such that the support member of the upper backrest adjustment device is mounted on the first and second uprights of the backrest frame so as to pivot about a transverse axis.

Abstract: The present invention relates to peptides and compositions for use in improving transduction efficiency of viruses into target cells.

Abstract: The present invention aims to provide a therapeutic drug for cancer having a superior treatment effect. A cancer treatment using a CBP/catenin inhibitor and an immune checkpoint inhibitor in combination not only increases a treatment effect on cancer, but also enables an effective treatment of cancer patients showing low sensitivity when an immune checkpoint inhibitor is used alone.

Abstract: The invention relates to a CD5L-binding agent or a pharmaceutical composition thereof for use in the treatment of cancer by inhibiting macrophage M2 activation or promoting lymphocyte activation.

Abstract: Antisense oligonucleotides are provided. These antisense oligonucleotides are useful in the preparation of gapmers for inhibition of Tau mRNA transcription. Inhibition of Tau mRNA transcription may result in decrease of amounts of Tau protein in a subject, allowing treatment of diseases and disorders related to expression of Tau, including Alzheimer's disease and primary tauopathies.

Abstract: The present invention relates to combination of actives that provides synergistic preservative action especially for use in personal care compositions. The preservative system comprises a combination of sodium benzoate and a second active selected from benzhydroxamic acid or tricarballylic acid.

Abstract: A compound for regulating body weight imbalance, a composition thereof and an application thereof. The inventor unexpectedly discovered that diosmin hydrogen sulfate derivatives have the effects of regulating body weight imbalance, and are expected to be developed as safe and effective weight imbalance regulators or used as synergists to improve the regulatory effects of existing weight imbalance regulators.

Abstract: Method of manufacturing a photovoltaic cell, comprising the steps of: providing a photovoltaic conversion device; providing a transparent conductive oxide layer upon at least a first face of said photovoltaic conversion device; forming a self-assembled monolayer on said transparent conductive oxide layer, said self-assembled monolayer being based on molecules terminated by at least one group F which is chosen from: a phosphonic acid group, a P(O)O2?M+ group, a OPO3H2 group, or an OP(O)O2?M+ group, wherein M+ is a metal cation; patterning said self-assembled monolayer so as to define at least one plateable zone in which said transparent conductive oxide layer is exposed; plating a metal onto said at least one plateable zone.