Abstract: The present disclosure relates to methods of mining a block of a distributed ledger. The methods include: receiving a block to be mined, the block including a header hash and a plurality of transactions; creating a first signature based on a first function, where inputs to the first function include the header hash and the plurality of transactions; and creating a second signature based on a second function, where an input to the second function is the first signature. In one example, the second function is a multiplicative inverse function and the method further includes creating the second signature that is a multiplicative inverse value of the first signature with respect to a first irreducible polynomial. The method additionally includes creating a chain of signatures, where each of the signatures is a multiplicative inverse value of a previous output with respect to a respective irreducible polynomial.

Abstract: An artificial ligament prosthesis which is notable in that it comprises a layer totally or partly consisting of PCL fibres. The ligament prosthesis is a biodegradable and “biointegrable” artificial ligament which makes it possible to take away all the apprehensions and uncertainties due to non-degradable synthetic supports. It is a prosthetic structure inspired by and similar to the native tissue, which is biodegradable while being sterilisable. It can optionally be seeded in order to facilitate the formation of functional tissues with controlled cell and tissue activity, having the required mechanical properties. The prosthesis maybe slowly resorbable in order to be gradually replaced with a functional tissue identical to that of the native ligament.

Abstract: A system for the therapeutic treatment of joints comprising a composite material comprising a biodegradable polymer matrix and a plurality of piezoelectric particles adapted to generate local electric charges in response to an external stimulation made by means of ultrasound, said plurality of piezoelectric particles being dispersed in the matrix. The composite material also comprises a plurality of stamina cells dispersed in the biodegradable polymer matrix and a plurality of carbon-based particles. The system also comprises a releasing device, arranged to deposit the composite material in a joint cavity at predetermined areas of the cartilage, and a stimulator device arranged to emit ultrasound at a predetermined frequency, a predetermined intensity and for a predetermined time of application, in such a way that, when the device is located near a joint wherein the composite material has been deposited, said ultrasound stimulate the plurality of piezoelectric particles.

Abstract: The present invention is in the field of antiperspirant compositions, in particular, compositions comprising antiperspirant actives.

Abstract: The invention comprises a process for preparing mixtures of DEFI and amide taurate (ATA) having excellent yields of ATA and substantial absence of browning of final ATA and DEFI mixtures. The process permits much greater flexibility in ratios of DEFI to ATA. The invention further relates to mixtures prepared by processes of the invention.

Abstract: A solar power system for a metal shingled roof, including: a plurality of metal roofing shingles; and a plurality of solar module mounting assemblies, wherein each of the solar module mounting assemblies has upper and lower module cleats that support upper and lower solar module frames thereon such that the upper and lower module frames are both spaced apart in a direction parallel to the roof, and spaced apart in a direction perpendicular to the roof.

Abstract: The present invention relates to impregnated inorganic porous particles comprising a eutectic mixture of thymol and menthol. The invention also relates to powder compositions comprising said particles. The invention further relates to methods of cleaning surfaces using said particles and compositions.

Abstract: Systems, kits, and related methods of making fecal transplants are described. In an embodiment, the system comprises a sample collector defining a sample collection chamber shaped to collect a fecal sample from fecal matter; a sample processing module defining a sample port shaped to receive the sample collector and comprising: a channel positioned to receive at a proximal end of the channel the fecal sample from the sample collection chamber when the sample collector is received by the sample port; and a capsule fluidically coupled to a distal end of the channel adapted to receive a portion of the fecal sample passed therethrough; and a sample processing unit comprising: a housing defining an opening shaped to receive the sample processing module; and an actuator disposed in the housing and configured to urge the sample from the sample collection chamber through the channel to the capsule.

Abstract: A solar power system for a metal shingled roof, including: a plurality of metal roofing shingles; and a plurality of solar module mounting assemblies, wherein each of the solar module mounting assemblies has upper and lower module cleats that support upper and lower solar module frames thereon such that the upper and lower module frames are both spaced apart in a direction parallel to the roof, and spaced apart in a direction perpendicular to the roof.

Abstract: The present invention relates to a savoury, particulate composition having a water content of not more than 15 wt. % and comprising: a) 5-99 wt. %, by weight of the composition, tomato powder, wherein at least 70 wt. % of said tomato powder has a mesh size of less than 850 ?m, b) 0.5-5 wt. %, by weight of the tomato powder, calcium carbonate powder, said calcium carbonate powder having a volume median grain diameter (D50) of 0.1-50 ?m.

Abstract: Systems and methods of blocking a biological vessel 2 are provided. The systems and methods may comprise introducing to the vessel an amphiphilic peptide. The peptide may comprise at least thirteen amino acids that may alternate between a hydrophobic amino acid and a hydrophilic amino acid. The peptide may form a beta- sheet spontaneously in an aqueous solution in the presence of a cation.

Abstract: Computational systems implement problem solving using hybrid digital/quantum computing approaches. A problem may be represented as a problem graph which is larger and/or has higher connectivity than a working and/or hardware graph of a quantum processor. A quantum processor may be used determine approximate solutions, which solutions are provided as initial states to one or more digital processors which may implement classical post-processing to generate improved solutions. Techniques for solving problems on extended, more-connected, and/or “virtual full yield” variations of the processor's actual working and/or hardware graphs are provided. A method of operation in a computational system comprising a quantum processor includes partitioning a problem graph into sub-problem graphs, and embedding a sub-problem graph onto the working graph of the quantum processor. The quantum processor and a non-quantum processor-based device generate partial samples.

Abstract: A support for household appliance comprises a hydraulic plate; a sheath connected with the hydraulic plate; a regulating support in the sheath; an accommodation chamber formed by the hydraulic plate, the sheath and the regulating support; and a flexible accommodation body, which accommodates a liquid medium and is arranged in the accommodation chamber. The flexible accommodation body extends and retracts to drive the regulating support to axially move in the sheath for leveling under action of pressure; and the sheath and/or the regulating support are/is provided with a guiding limiting mechanism for limiting the circumferential rotation of the regulating support relative to the sheath. A yielding part corresponding to the guiding limiting mechanism is formed in the hydraulic plate. The overall height of the support for household appliance is lowered, and the stability of shock absorption of the support for household appliance is improved.

Abstract: The invention provides substituted imidazo[1,2-a]pyridine compounds, substituted imidazo[1,2-a]pyrazine compounds, related compounds, compositions containing such compounds, medical kits, and methods for using such compounds and compositions to treat medical disorders, e.g., Gaucher disease, Parkinson's disease, Lewy body disease, dementia, or multiple system atrophy, in a patient. Exemplary imidazo[1,2-a] pyridine compounds described herein include substituted 5-methyl imidazo[1,2-a]pyridine-8-carboxamide compounds and variants thereof.

Abstract: A quantum processor is operable as a universal adiabatic quantum computing system. The quantum processor includes physical qubits, with at least a first and second communicative coupling available between pairs of qubits via an in-situ tunable superconducting capacitive coupler and an in-situ tunable superconducting inductive coupler, respectively. Tunable couplers provide diagonal and off-diagonal coupling. Compound Josephson junctions (CJJs) of the tunable couplers are responsive to a flux bias to tune a sign and magnitude of a sum of a capacitance of a fixed capacitor and a tunable capacitance which is mediated across a pair of coupling capacitors. The qubits may be hybrid qubits, operable in a flux regime or a charge regime. Qubits may include a pair of CJJs that interrupt a loop of material and which are separated by an island of superconducting material which is voltage biased with respect to a qubit body.

Abstract: A portable device for transporting asphalt repair materials for use in repairing potholes in asphalt pavements. The device has a body with a hopper compartment for transporting and dispensing asphalt mix materials. Emulsion oils are held and dispensed from a separate emulsion oil tank. An emulsion pump provides emulsion oils to a spray wand. The emulsion oil tank includes an emulsion rejuvenator apparatus which works to prevent separation of the emulsion oils. A control circuit actuates the rejuvenator any time that the emulsion pump is turned on to supply emulsion oils to a spray wand to spray emulsions onto the road repair site.

Abstract: A propulsion system for small artificial satellites comprises a plurality of engines (2) fixable to a frame (101) of a satellite (100); a control unit (3) connected functionally to the engines (2) for sending at least one activation signal (AS) for activating at least one engine (2); the system is selectively configurable at least between a first configuration in which at least one of the engines (2) is activated for correcting the orbit of the satellite (100) and a second configuration in which at least one of the engines (2) is activated for dispersing said satellite (100) relative to another adjacent satellite.

Abstract: The present invention relates to the field of neurodegenerative diseases. More specifically, the present invention relates to a screening assay to produce compounds stabilizing the gamma-secretase enzyme substrate complex, thereby increasing gamma-secretase processivity while attenuating the release of longer A? peptides. More specifically, gamma-secretase stabilizing compounds increase thermostability of the enzyme/substrate complexes acting in the sequential ?-secretase processing of APP, to result in reduced amyloidogenic A? production, thereby preventing Alzheimer disease.

Abstract: Adapter (26, 26?) for connecting a windscreen wiper blade (12) to a driving arm (14), the adapter (26, 26?) having a ‘U’-section formed by a base and two flanks (42a, 42b) delimiting a housing (45) in which: at least one (42a) of the flanks is formed by at least two walls (42aa, 42bb) separated from one another by at least one cavity (63, 64), and at least one protuberance (60) is connected to at least one of the walls (42aa, 42ab, 42ba, 42bb) and extends at least in part inside said housing (45).

Abstract: Laundry liquid composition comprising a benzoate salt and a linear alkyl benzoate surfactant, said composition having a pH of from 5 to 7.5. A method for preserving a laundry liquid composition comprising linear alkyl benzoate and having a pH of from 5 to 7.5 by adding a benzoate salt.