Abstract: A method for a tactile presentation of perceivable content. The method comprises receiving a data representing perceivable content, selecting a plurality of electric currents according to the data, each the electric current is associated with at least one of a plurality of regions of a solution having a plurality of macromolecules, and changing a level of acidity (pH) of at least one of the plurality of regions by applying a respective the electric current thereto. A proton concentration in the plurality of regions tactilely presents the perceivable content.
Type:
Grant
Filed:
March 25, 2009
Date of Patent:
June 23, 2015
Assignee:
Technion Research & Development Foundation Limited
Abstract: Polymeric foams and elastomer/hydrogel bicontinuous composite structures derived from high internal phase emulsions and possessing shape-memory characteristics are disclosed, as well as processes for forming the same and uses thereof in, for example, manufacturing of various articles.
Type:
Application
Filed:
December 22, 2014
Publication date:
June 18, 2015
Applicant:
Technion Research & Development Foundation Limited
Inventors:
Michael S. SILVERSTEIN, Inna Gurevitch, Christine Warwar
Abstract: A system for optical coherence tomography (OCT) is disclosed. The system comprises an optical interferometer apparatus configured to split an optical beam into a reference beam directed to a reference reflector and a sample beam directed to a sample, and to combine a reflected beam from the reference reflector with a returning beam from the sample to form a combined optical signal. The system further comprises a two photon detector configured to detect the combined optical signal by two photon absorption and to provide a corresponding electrical signal, a frequency separation system configured to separate a low frequency component from the electrical signal, and a data processor configured for providing a topographic reconstruction of the sample based, at least in part, on the low frequency component.
Type:
Application
Filed:
May 6, 2013
Publication date:
June 18, 2015
Applicant:
Technion Research & Development Foundation Limited
Inventors:
Amir Nevet, Tomer Michael, Meir Orenstein
Abstract: In a data storage and retrieval system wherein data arranged in nodes is stored and retrieved in pages, each page comprising a cluster of nodes, a method comprising: monitoring ongoing data retrieval to find retrieval patterns of nodes which are retrieved together and to identify changes in said retrieval patterns over time; and periodically reclustering the data nodes among said pages dynamically during usage of the data to reflect said changes, so that nodes more often retrieved together are migrated to cluster together and nodes more often required separately are migrated to cluster separately, thereby to keep small an overall number of page accesses of said data storage and retrieval system during data retrieval despite dynamic changes in patterns of data retrieval. The low number of page accesses allows the reclustering to be carried out concurrently with data access.
Type:
Grant
Filed:
September 12, 2013
Date of Patent:
June 16, 2015
Assignee:
Technion Research & Development Foundation Limited
Abstract: A method for calculating a reconstructed phase that includes: Calculating a current phase signal and current amplitude signal that represent a phase and amplitude of a current input symbol, respectively. Generating, in response to the current phase signal and an estimate of a phase of a last input symbol that preceded the current input symbol, multiple partial references, some of which are responsive to (i) phase signals representative of phases of a plurality of input symbols that preceded the current input symbol, and (ii) estimates of the phase of the plurality of input symbols. Calculating unwrapped partial references. Estimating a constant carrier frequency offset (CFO) phase rotation in response to the unwrapped partial references. Calculating a reconstructed phase of the current input symbol in response to, at least, the estimate of the constant CFO phase rotation and to the unwrapped partial references.
Type:
Grant
Filed:
March 11, 2014
Date of Patent:
June 16, 2015
Assignee:
TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LTD.
Inventors:
Moshe Nazarathy, Igor Tselniker, Alex Tolmachev
Abstract: A method of forming an image of a target that comprises illuminating a target with light, maneuvering an optical unit having at least one diffractive element in front of the target through a plurality of positions, capturing, during the maneuvering, a plurality of spectrally encoded frames each from a portion of the light that is scattered from a different of a plurality of overlapping segments along a track traversing an image plane of the target, and combining the plurality of spectrally encoded frames to form a composite multispectral image of at least a portion of said target.
Type:
Grant
Filed:
July 27, 2011
Date of Patent:
June 2, 2015
Assignee:
Technion Research & Development Foundation Limited
Abstract: A method of expanding and maintaining human embryonic stem cells (ESCs) in an undifferentiated state by culturing the ESCs in a suspension culture under culturing conditions devoid of substrate adherence is provided. Also provided are a method of deriving ESC lines in the suspension culture and methods of generating lineage-specific cells from ESCs which were expanded in the suspension culture of the present invention.
Type:
Grant
Filed:
August 2, 2007
Date of Patent:
May 26, 2015
Assignee:
Technion Research & Development Foundation Limited
Abstract: A method of projection domain processing based on a local transform and shrinkage for use in reconstructing digital images from a set of projections, the method including providing a target image of a target object, providing projection data of the target object, producing filtered projection data by applying a sparsifying transform and a shrinkage function to the projection data, followed by an inverse of the sparsifying transform, producing a restored image by applying a reconstruction transform to the filtered projection data, comparing the restored image to the target image, and producing an optimized projection domain shrinkage function by adapting the shrinkage function to minimize differences between the restored image and the target image. Related apparatus and methods are also described.
Type:
Grant
Filed:
October 23, 2013
Date of Patent:
May 19, 2015
Assignee:
Technion Research & Development Foundation Limited
Inventors:
Michael Elad, Joseph Shtok, Michael Zibulevsky
Abstract: A device for isoelectric focusing. The device comprises a focusing container configured to contain an electrolyte solution and having a longitudinal axis and at least one electrolysis unit mounted in a close proximity to the longitudinal axis. Each electrolysis unit injects an ion flow into the focusing container so as to create a pH gradient having a plurality of steps in the electrolyte solution, along the longitudinal axis. Each step has a substantially uniform pH level and the pH gradient is defined by at least one pH ramp between every two sequential steps of the plurality of steps.
Type:
Grant
Filed:
August 18, 2010
Date of Patent:
May 12, 2015
Assignee:
Technion Research & Development Foundation Limited
Abstract: A composition-of-matter comprising an antibody or antibody fragment including an antigen-binding region capable of specifically binding an antigen-presenting portion of a complex composed of a human antigen-presenting molecule and an antigen derived from a pathogen is disclosed.
Type:
Grant
Filed:
November 17, 2009
Date of Patent:
May 5, 2015
Assignee:
Technion Research & Development Foundation Limited
Abstract: The present invention provides HIV-derived lentivectors which are safe, highly efficient, and very potent for expressing transgenes for human gene therapy, especially, in human hematopoietic progenitor cells as well as in all other blood cell derivatives. The lentiviral vectors comprise a self-inactivating configuration for biosafety and promoters such as the EF1 ? promoter as one example. Additional promoters are also described. The vectors can also comprise additional transcription enhancing elements such as the wood chuck hepatitis virus post-transcriptional regulatory element. These vectors therefore provide useful tools for genetic treatments such as inherited and acquired lympho-hematological disorders, gene-therapies for cancers especially the hematological cancers, as well as for the study of hematopoiesis via lentivector-mediated modification of human HSCs.
Abstract: A composition-of-matter comprising an antibody or antibody fragment including an antigen-binding region capable of specifically binding an antigen-presenting portion of a complex composed of a human antigen-presenting molecule and an antigen derived from a pathogen is disclosed.
Type:
Application
Filed:
January 12, 2015
Publication date:
April 30, 2015
Applicant:
TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITED
Abstract: Provided herein are immunoreactive peptides which can selectively bind Ehrlichia-specific anti-p120 or anti-p140 antibodies. Methods and kits utilizing the immunoreactive peptides are also provided. The immunoreactive peptides may be utilized, e.g., for determining whether or not a subject is infected with Ehrlichia chaffeensis or Ehrlichia canis. In certain embodiments, the immunoreactive peptides may be utilized in an ELISA or lateral flow assay.
Abstract: Provided are serum-free culture media which comprise basic fibroblast growth factor (bFGF), transforming growth factor beta-3, ascorbic acid, xeno-free serum replacement and a lipid mixture. The media may also comprise an IL6R/IL6 chimera, or leukemia inhibitory factor (LIF); wherein the culture medium is capable of maintaining pluripotent stem cells in an undifferentiated state in the absence of feeder cell support. Also provided are cell cultures comprising pluripotent stem cells such as human embryonic stem cells and induced pluripotent stem (iPS) cells, and methods of using the same for expanding pluripotent stem cells in an undifferentiated state using two-dimensional or three-dimensional culture systems. Methods of expanding iPS cells in a suspension culture devoid of substrate adherence and cell encapsulation are also provided.
Type:
Grant
Filed:
November 11, 2010
Date of Patent:
April 28, 2015
Assignee:
Technion Research & Development Foundation Limited
Abstract: The present invention is directed to co-assembled nanoparticle composition comprising denatured ?-lactoglobulin and at least one nutraceutical compound, specifically polyphenols, such as EGCG, compositions comprising same and methods of preparing thereof.
Type:
Grant
Filed:
October 17, 2011
Date of Patent:
April 14, 2015
Assignee:
Technion Research and Development Foundation Ltd.
Abstract: A method for photogrammetric texture mapping using casual images is provided. The method may include the following steps: estimating, for each vertex of at least a portion of a three dimensional (3D) mesh representing a model, projection parameters associated with a virtual camera that is unique for each vertex; mapping pixels from a two dimensional (2D) image to the vertices, such that each mapping of a pixel is based on the estimated respective virtual camera parameters; and texturing the portion of the mesh with corresponding mapped pixels wherein vertices on the textured portion are selected such that they are visible from a specified viewpoint associated with the 3D mesh.
Type:
Grant
Filed:
September 10, 2013
Date of Patent:
April 14, 2015
Assignee:
Technion Research and Development Foundation Ltd.
Abstract: Provided herein are monoclonal antibodies against Olfml-3. In some aspects, methods for treating angiogenesis-related conditions, such as cancer, are provided comprising administering an Olfml-3-binding antibody of the embodiments.
Type:
Application
Filed:
October 9, 2014
Publication date:
April 9, 2015
Applicant:
RESEARCH DEVELOPMENT FOUNDATION
Inventors:
Beat A. IMHOF, Marijana MILJKOVIC-LICINA, Philippe HAMMEL
Abstract: The present invention provides a sensor apparatus based on 2D films or 3D assemblies of cubic nanoparticles capped with an organic coating. The apparatus is used to determine the composition and preferably measure the concentration of volatile and non-volatile compounds in a sample, with very high sensitivity. Methods for use of the apparatus in applications such as diagnosis of disease, food quality and environmental control are disclosed.
Type:
Grant
Filed:
November 20, 2008
Date of Patent:
April 7, 2015
Assignee:
Technion Research and Development Foundation Ltd.
Abstract: A device, a computer readable medium and a method that may include performing a shortened read attempt of multiple data memory cells that store data to provide an estimate of the data; wherein the shortened read attempt has a duration that is shorter than a duration of a full read attempt; performing a shortened read attempt of redundant memory cells that store redundant information to provide an estimate of the redundant information; wherein the estimate of the redundant information is indicative of an expected number of data memory cells that store a certain logic value; determining, based on the estimate of the data, an estimated number of data memory cells that store the certain logic value; comparing the expected number to the estimated number; and providing the estimate of the data as a read result if the expected number and the estimated number equal each other.
Type:
Grant
Filed:
July 12, 2012
Date of Patent:
March 31, 2015
Assignee:
Technion Research and Development Foundation Ltd.