Abstract: An in-chip monitoring method and apparatus are disclosed. In one embodiment the apparatus includes a test pad, a transmission gate and a plurality of test components coupled to the transmission gate. The transmission gate is attached to a substrate and adapted to receive a code word uniquely addressed to one of the plurality of test components. In a further embodiment, the transmission gate is further adapted to relay an output of the one of the plurality of test components to the test pad, in response to receipt of the code word.
Type:
Grant
Filed:
January 16, 2002
Date of Patent:
May 24, 2005
Assignee:
Microtune (San Diego), Inc.
Inventors:
Jonathon Cheah, Chee Kwang Quek, Ee Hong Kwek
Abstract: A grilling apparatus including an ash receptacle and a grill assembly. The grill assembly includes a firebox and at least one support arm connecting the firebox to the ash receptacle for pivotal movement of the grill assembly between a cooking position and a cleaning position. In an alternative embodiment, the grilling apparatus includes two grill assemblies coupled to the ash receptacle for pivotal movement between cooking and cleaning positions.
Abstract: A wireless receiver e.g., a Bluetooth-compatible receiver or a receive chain in a Bluetooth-compatible transceiver, includes a discriminator unit and a timing recovery unit. The output of the discriminator unit is provided as an input to the timing recovery unit, which timing recovery unit is configured to align a free-running clock of the receiver with a received signal to extract received data therefrom.
Abstract: The invention provides methods for identifying a modulator of quorum sensing signaling in bacteria, and for identifying a quorum sensing controlled gene in bacteria. In addition, the invention provides quorum sensing controlled genetic loci in Pseudomas aeruginosa. Novel indicator strains and vectors for engineering the strains for use in the method of the invention are also provided.
Type:
Grant
Filed:
September 1, 2000
Date of Patent:
February 15, 2005
Assignees:
University of Iowa Research Foundation, Vertex Pharmaceuticals (San Diego) LLC
Inventors:
Marvin Whiteley, Kimberly M. Lee, E. Peter Greenberg, Ute Muh
Abstract: The present invention relates to hepatitis virus core proteins and nucleic acids. In particular, the present invention provides compositions and methods comprising recombinant hepatitis virus core proteins or nucleic acids for use in vaccine formulations.
Type:
Application
Filed:
July 30, 2003
Publication date:
February 3, 2005
Applicant:
Vaccine Research Institute of San Diego
Abstract: The present invention relates to reporter gene constructs encoding a cytoplasmic form of chitobiase (N,N?-diacetylchitobiase) and methods of using these reporter gene constructs. The use of a cytoplasmic form of chitobiase as a reporter enzyme is generally applicable to the study of gene expression in organisms which do not contain N-acetyl-?-D-glucosaminidases.
Abstract: A method and apparatus for tuning a VCO circuit to provide desired modulations is described. In one embodiment, the method of the present invention uses a controlled voltage from a digital-to-analog converter to obtain VCO voltage/frequency characteristics. The VCO voltage/frequency characteristics are used to determine a VCO capacitance value as well as a charge pump current level for each frequency band of interest. For one embodiment, the VCO circuit includes a bank of switchable capacitors used to set the VCO capacitance value. The charge pump includes a number of switch-controlled current meters to set the charge pump current level. The VCO capacitors and charge pump current meters are controlled by an off-chip CPU.
Type:
Grant
Filed:
January 16, 2002
Date of Patent:
December 28, 2004
Assignee:
Microtune (San Diego), Inc.
Inventors:
Shih-Tsung Yang, Jonathon Y. Cheah, Ee Hong Kwek, Chun-Yip Antony Lau
Abstract: An appliance is provided for connecting the water-tight cap of an endoscope or bronchoscope to the proximal body of the endoscope or bronchoscope, respectively. In one version of the invention, one end of the appliance is connected to the “S” connector of the proximal body of the endoscope, as described in detail herein. In another version of the invention, one end of the appliance is wrapped around the proximal body of the endoscope, as described in detail herein. The invention also includes methods of operating the appliance.
Abstract: A microplate lid having a substantially flat, generally rectangular top with first and second pairs of opposite sides. A flange depends from the top of the first and second pairs of sides, the flange bearings at least one recess area along each side of the first pair of sides, the recessed area extended into the top.
Type:
Grant
Filed:
November 27, 2000
Date of Patent:
November 30, 2004
Assignee:
Vertex Pharmaceuticals (San Diego) LLC
Inventors:
Christopher B. Shumate, Peter J. Coassin
Abstract: The present invention provides plants that exhibit modulated reproductive development and methods of modulating the timing of reproductive development in plants.
Type:
Application
Filed:
March 4, 2004
Publication date:
November 18, 2004
Applicant:
University of California, San Diego Technology Transfer and Intellectual Property Services
Inventors:
Martin F. Yanofsky, Soraya Pelaz, Gary Ditta
Abstract: A potent peptide inhibitor (SuperSog) of TGF-&bgr; family growth factor signalling, peptide variants thereof and nucleotide coding sequences therefor are provided by the invention. The Super-Sog peptide comprises a fragment of the Drosophilia short gastrulation (Sog) gene which includes the CR-1 cysteine-rich repeat of Sog. Methods and compositions for use of Super-Sog in therapeutic and diagnostic applications are also provided.
Abstract: A sampling system includes a rocket body, and a first sampling vessel coupled to the rocket body, wherein, during operation, a propellant is discharged from the rocket body and causing the rocket body to be propelled towards a body of liquid. The sampling system may also include a deployment line coupled to the rocket body at a first point on the line, the deployment line also coupled proximate to a launching area at a second point on the line, wherein, subsequent to the discharge of the propellant, the rocket is retrieved by an operator using the deployment line.
Abstract: The present invention provides compounds which inhibit serine protease activity of matriptase or MTSP1. Also provided are pharmaceutical compositions comprising those compounds and methods of using the compounds and pharmaceutical compositions to treat conditions ameliorated by inhibition of matriptase or MTSP1. The invention provides recombinant serine protease domains and methods of using peptides comprising a recombinant serine protease domain to screen for compounds that inhibit serine protease activity of matriptase or MTSP1.
Type:
Grant
Filed:
September 8, 2000
Date of Patent:
September 28, 2004
Assignee:
Dendreon San Diego LLC
Inventors:
Edwin L. Madison, Joseph Edward Semple, Gary Samuel Coombs, John Eugene Reiner, Edgar O. Ong, Gian Luca Araldi
Abstract: A sequence of cards is stored that graphically represents available options within an information system. In response to a single user action, the sequence of cards is successively displayed within a focus area of the user interface. In response to a subsequent user action, the successive display is discontinued to display a particular card representing a selected option.
Type:
Application
Filed:
May 3, 2002
Publication date:
September 16, 2004
Applicant:
diego, inc.
Inventors:
James A. Billmaier, John M. Kellum, Dewey M. Reid, Philip A. Rogan
Abstract: A method is described comprising: receiving a synchronization packet transmitted form a first device; receiving a data packet transmitted from the first device, the data packet being offset from the synchronization packet by a particular amount of time; and identifying the first device based on the amount of time from which the data packet is offset from the synchronization packet. Also disclosed is a method implemented on a first wireless device comprising: transmitting a synchronization packet to a second wireless device; and transmitting a first data packet to the second wireless device, the first data packet being offset from the synchronization packet by a first amount of time, wherein the first amount of time from which the first data packet is offset from the synchronization packet identifies first wireless device to second wireless device.
Abstract: Engineered fluorescent proteins, nucleic acids encoding them and methods of use are provided.
Type:
Grant
Filed:
February 5, 2002
Date of Patent:
August 24, 2004
Assignees:
The Regents of the University of California, Vertex Pharmaceuticals (San Diego) LLC, State of Oregon Acting by and through the State Board of
Higher Education on behalf of the University of Oregon
Inventors:
Roger Y. Tsien, S. James Remington, Andrew B. Cubitt, Roger Heim, Mats F. Ormö
Abstract: A high-speed phase-frequency detection module is described to function at very high frequencies and to produce very low jitter. In one embodiment, high-speed phase-frequency detection module includes a PFD with edge-triggered asynchronous-reset true-single-phase-clocking (“TSPC”) D flip-flops that have very short CLK to Q and Reset to Q time delays. In one embodiment, the high-speed phase-frequency detection module includes a charge pump, without replica or feedback, that can respond to the very narrow pulses from the PFD and produce output voltages with small ripple, thus leading to low VCO output jitter.
Type:
Grant
Filed:
January 15, 2002
Date of Patent:
August 17, 2004
Assignee:
Microtune (San Diego), Inc.
Inventors:
Jonathon Cheah, Christopher Yong, Minjie Wu
Abstract: A VCO circuit for a fractional-n PLL circuit is described for implementing a direct modulation scheme. An embodiment of the invention provides a bank of switchable capacitors used to stringently control the gain of the VCO (KVCO). The capacitors provide the stringent control necessary for direct modulation. The bank of switchable capacitors is used to coarsely tune the VCO circuit. A linear capacitor is placed in series with, the varactor to linearize the frequency/capacitance response of the varactor. The capacitor also serves to isolate a reference voltage that is used to bias the varactor diode to ensure the linear range of the varactor is within the voltage range of the VCO circuit power supply. The varactor is used for fine tuning of the VCO circuit. For one embodiment the input voltages to the VCO are across a resistance value sufficient to dampen noise picked up through an external loop filter.
Abstract: The present invention relates to certain substituted heterocycles of Formula (I) which are useful in the treatment of diseases related to lipid and carbohydrate metabolism, such as type 2 diabetes, adipocyte differentiation, uncontrolled proliferation, such as lymphoma, Hodgkin's Disease, leukemia, breast cancer, prostate cancer or cancers in general; and inflammation, such as osteoarthritis, rheumatoid arthritis, Crohn's Disease or Inflammatory Bowel Disease.
Type:
Grant
Filed:
December 31, 2002
Date of Patent:
July 20, 2004
Assignee:
Incyte San Diego
Inventors:
Magnus Pfahl, Catherine Tachdjian, Hussien A. Al-Shamma, Andrea Fanjul, David P. M. Pleynet, Lyle W. Spruce
Abstract: A linescan camera is used in conjunction with a mechanical scanning mechanism to acquire high-resolution images of an area under video surveillance. The video signal from the linescan camera is converted into a digital data stream, compressed, and stored in a digital memory. Under control of an operator, full-field images are selectively recalled from the digital memory and converted to a lower resolution for display on a monitor. The operator selects a region-of-interest from the full-field display through the use of a computer pointing device, such as a mouse. The selected area is then displayed on the monitor in its full acquired resolution, thereby allowing the operator to view high-resolution images of a large area under surveillance.