Abstract: Some embodiments disclosed herein include systems and method for verifying meter accuracy. The system may include an electric vehicle charging station that includes a submeter that measures an amount of energy discharged from the electric vehicle charging station and to a connected electric vehicle. A meter test device may also be connected to the electric vehicle charging station to determine the accuracy of the submeter in local time.

Abstract: Microelectromechanical system are disclosed that include at least one electrode, microelectrode or combination thereof, wherein the at least one electrode comprises a carbon material, a glassy carbon material or a combination thereof. Contemplated systems are suitable for ?-ECoG arrays. Additional microelectromechanical systems are disclosed that include at least one electrode, microelectrode or combination thereof, wherein the at least one electrode comprises a carbon material, a glassy carbon material or a combination thereof; at least one substrate, surface, layer or a combination thereof, wherein the at least one electrode, microelectrode or combination thereof is disposed on, coupled with or otherwise layered on the at least one substrate, surface, layer or a combination thereof; and at least one bump pad, wherein the at least one electrode, microelectrode or combination thereof is coupled with the at least one bump pad via at least one conductive metal.

Abstract: The present invention is directed to a system and method for photoeradication of microorganisms from a target. The target is irradiated with pulsed purple or blue light in which (a) the light pulses have a peak irradiance and a pulse duration sufficient to optically excite a photoactive molecule capable of photoeradication of the microorganisms and (b) the light pulses are separated by an off time sufficient to allow the photoactive molecule to return to a ground state creating an oxidation reaction that produces free radicals which destroy a cellular structure of the microorganisms and thereby photoeradicate all or a portion of the microorganisms. The photoactive molecule may comprise either an endogenous molecule present in the microorganisms or an exogenous molecule applied to the target.

Abstract: A delivery system and method for a brewed beverage, such as coffee or tea, that stores a batch of brewed beverage in a cooled container, and heats a serving quantity on demand at the point of dispensing. A heater such as a tankless water heater may be connected to a dispensing line to generate hot servings on demand. Cold servings may also be provided. Quality control of the brewing process may be improved by brewing in a centralized, controlled environment and then shipping cooled containers to dispensing points such as coffee shops or cafés. Containers may be filled with a gas such as nitrogen to prevent oxidation, thereby preserving freshness during storage or shipping. At the dispensing site, containers may be refrigerated and attached to gas tanks to maintain the freshness as servings are dispensed.

Abstract: The invention provides a series of conformationally stable and selective kinase inhibitors, and methods of using the kinase inhibitors. The effect of atropisomerism on kinase selectivity was assessed, finding improved selectivity compared to rapidly interconverting parent compounds. The compounds herein are atropisomers having increased kinase selectivity, and are for use in treating conditions that benefit from selective kinase inhibition.

Abstract: The scope of this invention is to disclose the method of foaming a superior impact mitigation material, namely semi-closed cell hybrid polyurea foam, using scalable manufacturing process that is geometry-independent and allows for greater control of the resulting foam properties. while the process discussed herein, can be easily used to make complex geometries (e.g., padding foam for helmets, outsoles for walking and running shoes, body armors or other protection applications.

Abstract: A magnetic resonance imaging apparatus according to an embodiment includes sequence controlling circuitry and processing circuitry. The sequence controlling circuitry acquires a first piece of data by executing a first pulse sequence having a first Echo Time (TE) value, to acquire a second piece of data by executing a second pulse sequence having a second TE value different from the first TE value, and to acquire a third piece of data by executing a third pulse sequence having a third TE value different from the first and the second TE values. The processing circuitry extracts a signal related to water, a signal related to a first fat, and a signal related to a second fat, on the basis of the first piece of data, the second piece of data, and the third piece of data.

Abstract: A pipeline inspection system is described. The system comprises a body, cameras, support members, and light sources. The cameras are coupled to the body and configured to obtain image information related to an interior surface of the pipe. The support members extend away from the body in a radial direction to contact the interior surface of the pipe and support the body. An individual support member has a first end coupled to the body, and a second end configured to contact the interior surface of the pipe. The light sources are configured to light the interior surface of the pipe. They are coupled to the support members at or near the second end such that the light sources are located in one or more radial positions near the interior surface of the pipe, separated from the one or more cameras and the body by the one or more support members.

Abstract: Provided herein are systems and methods for applying materials to articles or projectiles in order to coat at least a portion of the projectile. An embodiment of disclosure provides launching the a projectile into a stream of fluid. The fluid may be a molten metal, powder suspension or slip to be later sintered, molten polymer, monomers to be later polymerized or gaseous species that can locally react with the projectile to produce coatings such as oxides, nitrides, carbides, etc. The passage of the projectile through the fluid results in a coating on the projectile.

Abstract: A device and method is described for electronic human prosthetics, and specifically a body-machine interface (BMI) device where the input, output and on-board computing are combined into a single unit to form a compact ECG, respiratory sensing, temperature-sensing-prosthetics device. The devices (BMIs) can also communicate with other body-machine interface devices (BMI) and/or with external controllers wirelessly. The compact device has ultrasonic battery charging system. One or more BMI can be wirelessly connected so that a closed loop of BMIs, or a BMI and an external controller, can wirelessly send trigger pulses to the stimulator over the heart, glossopharyngeal nerve(s) or diaphragm.

Abstract: Microelectromechanical system are disclosed that include at least one electrode, microelectrode or combination thereof, wherein the at least one electrode comprises a carbon material, a glassy carbon material or a combination thereof. Contemplated systems are suitable for ?-ECoG arrays. Additional microelectromechanical systems are disclosed that include at least one electrode, microelectrode or combination thereof, wherein the at least one electrode comprises a carbon material, a glassy carbon material or a combination thereof; at least one substrate, surface, layer or a combination thereof, wherein the at least one electrode, microelectrode or combination thereof is disposed on, coupled with or otherwise layered on the at least one substrate, surface, layer or a combination thereof; and at least one bump pad, wherein the at least one electrode, microelectrode or combination thereof is coupled with the at least one bump pad via at least one conductive metal.

Abstract: Herein reported are new tricyclic cytidine compounds, such as 8-diethylamino-tC (8-DEA-tC), that respond to DNA and/or RNA duplex formation with up to a 20-fold increase in fluorescent quantum yield as compared with the free nucleoside, depending on neighboring bases. This turn-on response to duplex formation is by far the greatest of any reported nucleoside analogue that can participate in Watson-Crick base pairing. Measurements of the quantum yield of 8-DEA-tC mispaired with adenosine and, separately, opposite an abasic site show that there is almost no fluorescence increase without the formation of correct Watson-Crick hydrogen bonds. Kinetic isotope effects from the use of deuterated buffer show that the duplex protects 8-DEA-tC against quenching by excited state proton transfer. DFT calculations provide a rationale for the observed photophysical properties that is dependent on duplex integrity and the electronic structure of the analogue.

Abstract: This application relates to techniques for obtaining wide area intermittent video (WAIV). Some embodiments disclosed herein include a method of obtaining WAIV. The method can include, for example, capturing images at a series of sensor stations having pre-determined locations along a flightline. The flightline can be repeated one or more times, where images are captured at the same sensor stations with each pass of the flightline. The captured images from the same sensor station may have replicated view geometry and may be co-registered and precisely aligned with pixel-level precision. The captured images from multiple sensor stations through time may also be displayed together based upon absolute or relative sensor station locations to create a temporal sequence of wide area intermittent video. The approach provides efficient methods for creating wide area video with reduced temporal imaging frame rates. Systems and devices for forming wide area intermittent video are also disclosed.

Abstract: An article for treating the rim of a beverage glass includes a tray, an edible liquid substance, an edible particulate substance, and a cover. The sheet has an upper surface with a plurality of recesses extending downwardly from the upper surface. The edible liquid substance and the edible particulate substances are separately disposed in different recesses. The cover is assembled to the upper surface to retain the edible substances within the recesses.

Abstract: Disclosed and described herein are smart, high-speed UV communication protocols, inspired by the biological principles. The disclosed and described protocols use a ‘pipe’ routing topology to deliver large amount of data among the UVs equipped with multi-beam antennas. The disclosed and described embodiments include bio-inspired pipe routing and adaptive batch coding (ABC) based congestion control. In regard to bio-inspired pipe routing, a human's brain uses highly cooperative neuro cells to memorize everything. Inspired by neuro networks, a pipe architecture with high-throughput node-to-node data delivery is disclosed and described herein. The pipe routing uses multi-beam antennas to achieve parallel data transmission. In regard to ABC based congestion control, a new network coding called ABC is disclosed, which can minimize traffic congestion occurrences in the above pipe routing. The disclosed and described transport layer protocol includes both end-to-end reliability and congestion control.

Abstract: Provided are compositions, e.g., multiplexed platforms or systems, to screen for molecules, e.g., small molecule active agents such as drugs, that inhibit enzymes such as proteases. Provided are cell-based or multiplexed platforms for monitoring or assay the activity of a protease. Provided are cell-based assays and multiplexed systems for the monitoring of enzyme, activity such as proteolytic cleavage on the cell surface, where optionally the protein, e.g., an enzyme, can be naturally expressed on the cell surface or engineered to be expressed on the cell's surface. Provided are cells and stable cell lines expressing an “assay construct” and an enzyme of interest, where optionally one cell or cell line expresses both the “assay construct” and the enzyme, or two different cells or independent cell lines are used and mixed in the assay, where one expresses the “assay construct” with the enzyme substrate and the second expressing the enzyme.

Abstract: The invention provides a series of conformationally stable and selective kinase inhibitors, and methods of using the kinase inhibitors. The effect of atropisomerism on kinase selectivity was assessed, finding improved selectivity compared to rapidly interconverting parent compounds. The compounds herein are atropisomers having increased kinase selectivity, and are for use in treating conditions that benefit from selective kinase inhibition.

Abstract: Systems and methods facilitating objective evaluations of subjects to facilitate detecting clinically relevant changes in balance are provided. The system includes a portable balance board with a sensor in each of four feet for detecting downward force. Each sensor is communicatively coupled to a circuit board with a wired or wireless communication capability. A subject stands on the balance board and each sensor sends a signal to the circuit board, which communicates the four signals to a companion device that uses the signals to calculate the center of pressure (“COP”) of the subject over time. The subject can perform the BESS test and the resulting COP data is used to calculate a field path length for the subject. The field path length is compared to a previously determined baseline path length for the subject to detect any clinically relevant change in balance of the subject.

Abstract: A system for managing grid interaction with an energy storage device includes an energy exchange server, a plurality of energy storage devices, a plurality of interconnect socket adapters, and a plurality of energy exchange controllers, each energy exchange controller coupling to one of the plurality of interconnect socket adapters and dictating energy consumption based on energy pricing data received from the energy exchange server.

Abstract: Non-conductive films for constructing lighter than air balloons are provided. A non-conductive film may comprise multiple layers of gas barrier polymers. An outer surface printable layer and an interior heat or ultrasonically sealable layer may also be included. Each gas barrier film may comprise multiple (e.g., from 3 to approximately 75) barrier layers. A gas barrier core has a nano-layer structure. A gas barrier core may also comprise a biodegradable film or a bio-based film. A non-conductive film may comprise a metal layer for enhancing gas barrier properties. The metal layer may be discontinuous. The metal layer may be conductive and coated with an insulating top coat.