Abstract: The present invention describes a process for making cheese, comprising: a) adding to milk a carbohydrase selected from the group consisting of ?-galactosidase, N-acetyl-galactosaminidase and neuraminidase, b) incubating so as to partially deglycosylate ?-casein in the milk, and c) during or after step b) conditions causing clotting of the milk.

Abstract: A JFET integrated onto a substrate having a semiconductor layer at least and having source and drain contacts over an active area and made of first polysilicon (or other conductors such as refractive metal or silicide) and a self-aligned gate contact made of second polysilicon which has been polished back to be flush with a top surface of a dielectric layer covering the tops of the source and drain contacts. The dielectric layer preferably has a nitride cap to act as a polish stop. In some embodiments, nitride covers the entire dielectric layer covering the source and drain contacts as well as the field oxide region defining an active area for said JFET. An embodiment with an epitaxially grown channel region formed on the surface of the substrate is also disclosed.

Abstract: The present invention relates to the use of compounds of the formula (I) wherein the clotted line is an optional bond; R1 is butyl or butyryl if R2 is hydroxyl but is butyl if R2 is hydrogen; or R1 and R2 taken together are 1-butylidene optionally substituted by hydroxyl, methyl, or 3-(?,?-dimethylacrylyloxy)-pentylidenyl; X is a residue selected from the group consisting of X1, X2, X3, X4, and X5; wherein X is X2, X3 or X5 if the dotted line in formula (I) is absent; and X is X1, X4 or X5 if the dotted line signifies a bond in formula (I) above; R3 is hydroxyl or butyryl; and n is 1 or 2, as agents for the prevention, control and treatment of conditions requiring modulation of inflammation in mammals. In another aspect, the present invention relates to the use of compounds of the formula (I) as active ingredients in the manufacture of medicaments/compositions for the prevention, control and treatment of conditions requiring modulation of inflammation.

Abstract: A Junction Field-Effect transistor with no surface contact for the back gate and twice as much transconductance in the channel and with a higher switching speed is achieved by intentionally shorting the channel-well PN junction with the gate region. This is achieved by intentionally etching away field oxide outside the active area at least in the gate region so as to expose the sidewalls of the active area down to the channel-well PN junction or a buried gate which is in electrical contact with the well. Polysilicon is then deposited in the trench and doped heavily and an anneal step is used to drive impurities into the top and sidewalls of the channel region thereby creating a “wrap-around” gate region which reaches down the sidewalls of the channel region to the channel-well PN junction.

Abstract: The invention relates to a rope containing a plurality of stands comprising a mixture of high-performance poly-ethylene fibres and polytetraflooroethylene fibres in a mass ratio of 70:30 to 98:2. The rope shows markedly improved service life performance in cyclic bend-over-sheave applications. The invention also relates to the use of said rope as a load-bearing member in bend-over-sheave applications.

Abstract: Process for the coating of polymer particles, comprising contacting the particles with a composition comprising an additive, a film-forming binder that is miscible with the polymer, and a distributing agent, removing the distributing agent at a particle temperature at which the binder can form a film and that is below the softening temperature Tp of the polymer, and forming and consolidating an additive-containing layer of binder on the polymer particles, the polymer particles being kept in mutual motion while they are being contacted with the composition and while the additive-containing layer of binder is being formed and consolidated.

Abstract: Optical fiber coatings are disclosed having excellent ribbon stripping and adhesion behavior. The coatings are radiation-curable. The excellent stripping and adhesion behavior can be achieved by several means which include by use of additives, by use of radiation-curable oligomers having higher molecular weight, or by use of coatings having certain thermal properties. Combination of means can be employed. Stripping behavior can be measured by crack propagation and fiber friction measurements.

Abstract: Topical composition for use especially as a skin lightener, characterized in that it contains an effective amount of at least one compound of general formula (I) or a mixture of such compounds and/or an acid addition salt thereof: in which X is NH or a direct bond and n is 2, 3 or 4, preferably 2 or 3, and its use for lightening skin colour, for depigmenting liver spots and for evening out non-uniformities in skin colouration. The invention further relates to dermatologically effective compositions containing at least one disulfide of general formula (I) and at least one additional skin care ingredient.

Abstract: A method for modeling a circuit includes receiving a netlist that defines a plurality of connections between a plurality of circuit elements and identifying a subset of the connections. The method also includes routing the identified connections with a first group of wires having a first wire width and routing at least a portion of the remaining connections with a second wire width. The second wire width is smaller than the first wire width. The method further includes replacing the first group of wires with a third group of wires having the second wire width.

Abstract: A process for preparing racemic alkyl-5-halopent-4-enecarboxylic acids and esters thereof of the formula (I), in which R is a C1-C6-alkyl radical, R1 is H or C1-4-alkyl and X is chlorine, bromine or iodine, which comprises a) reacting a dialkyl alkylmalonate of the formula (II),in which R is as defined above and R2 is a C1-C4-alkyl radical, in the presence of a metal alkoxide of the formula MOR3, in which M may be Na, K or Li, and R3 is a C1-C4-alkyl radical, and in an organic solvent, with 1,3-dihalopropene to give the corresponding allylated malonate, then b) after full conversion, adding an inorganic salt and a C1-C6 alcohol to the reaction mixture, heating the reaction mixture to reflux temperature, then c) isolating the desired racemic ester of the formula (I) from the reaction mixture by extraction or direct distillation and d) if the racemic acid is the desired end product, hydrolyzing the ester function.

Abstract: The invention relates to a newly identified polynucleotide sequence comprising a gene that encodes a novel lipolytic enzyme from Aspergillus niger. The invention features the full length nucleotide sequence of the novel gene, the cDNA sequence comprising the full length coding sequence of the novel lipolytic enzyme as well as the amino acid sequence of the full-length functional protein and functional equivalents thereof. The invention also relates to methods of using these enzymes in industrial processes and methods of diagnosing fungal infections. Also included in the invention are cells transformed with a polynucleotide according to the invention and cells wherein a lipolytic enzyme according to the invention is genetically modified to enhance its activity and/or level of expression.

Abstract: This invention relates to unsaturated polyester resin or vinyl ester resin compositions comprising a polymer containing reactive unsaturations as a resin; a 1,3-dioxo-component, and optionally a reactive diluent and/or an inhibitor and/or a stabilizer; the resin compositions being curable with a peroxide component, and wherein the resin in the resin composition has an acid value=10; and the resin composition contains—while being cured—a base, which is either selected from the group of organic or inorganic oxides, hydroxides, alkoxides or carboxylates for each of which the cation has a redox potential of the metal of at most ?1V, or of ammonium ions; or is selected from the group of nitrogen-containing organic compounds. The present invention also relates to objects and structural parts prepared from such resin composition by curing with a peroxide.

Abstract: Cosmetic composition which can be applied topically, comprising at least one compound of the general formula (I) in which R1 is H, C1-C20-alkyl, cycloalkyl or aryl-C1-C4-alkyl, n is 1-4, X is —O—, —NH— or —NR2— and R2H or C1-C20-alkyl; and at least one compound corresponding to the above formula (I) but in which XR1 with X having the possible meaning of —NH— is the residue of an alpha-amino acid; use of these compounds and of the composition for stimulating the synthesis of the proteins of the basement membrane; and also both those compounds of the formula (I) in which X is —NR2— and both R1 and R2 are different from H, and the compounds corresponding to formula (I) but in which XR1 with X having the possible meaning of —NH— is the residue of an alpha-amino acid, as such.

Abstract: This invention is in the field of polymer chemistry. More in particular it provides a method to produce polymers such as block copolymers or cross-linked networks that are suitable for medical applications. The invention also provides degradable materials that may degrade completely when used in the human or animal body, minimizing residual components that may be toxic or otherwise undesirable.

Abstract: The invention related to a process for the polymerization of at least one aliphatic C2-20 or aromatic C4-20 hydrocarbyl mono- or multiolefin in the presence of a catalyst and an aluminum comprising co-catalyst, wherein the catalyst comprises a composition of a metal-organic reagent, a spectator ligand and optionally at least one equivalent of a hydrocarbylating agent. The invention further relates to a polymer obtainable by the process of the invention.

Abstract: The present invention relates to newly identified genes that encode proteins that are involved in the synthesis of L-ascorbic acid (hereinafter also referred to as Vitamin C). The invention also features polynucleotides comprising the full-length polynucleotide sequences of the novel genes and fragments thereof, the novel polypeptides encoded by the polynucleotides and fragments thereof, as well as their functional equivalents. The present invention also relates to the use of said polynucleotides and polypeptides as biotechnological tools in the production of Vitamin C from microorganisms, whereby a modification of said polynucleotides and/or encoded polypeptides has a direct or indirect impact on yield, production, and/or efficiency of production of the fermentation product in said microorganism. Also included are methods/processes of using the polynucleotides and modified polynucleotide sequences to transform host microorganisms.

Abstract: The present invention relates to a process for the production of vitamin C from L sorbosone using an aldehyde dehydrogenase which is isolated from Gluconobacter oxydans DSM 4025 (FERM BP-3812), said enzyme having the following physicochemical properties: (a) molecular weight of 150,000±6,000 Da or 230,000±9,000 Da (consisting of 2 or 3 homologous subunits, each subunit having a molecular weight of 75,000±3,000 Da); (b) substrate specificity as active on aldehyde compounds; (c) Cofactors are pyrroloquinoline quinone and heme c; (d) Optimum pH between 6.4 and 8.2 for vitamin C production from L-sorbosone; and (e) as inhibitors Co2+, Cu2+, Fe2+, Ni2+, Zn2+, monoiodoacetate and ethylendiamine tetraacetic acid. The process is performed in the presence of a suitable electron acceptor and the vitamin C isolated from the reaction mixture.

Abstract: A JFET structure with self-aligned metal source, drain and gate contacts with very low resistivity and very small feature sizes. Small source, drain and gate openings are etched in a thin dielectric layer which has a thickness set according to the desired source, gate and drain opening sizes, said dielectric layer having a nitride top layer. Metal is deposited on top of said dielectric layer to fill said openings and the metal is polished back to the top of the dielectric layer to achieve thin source, drain and gate contacts. Some embodiments include an anti-leakage poly-silicon layer lining the contact holes and all embodiments where spiking may occur include a barrier metal layer.

Abstract: 2-Butene-1.4-diol can be prepared by hydrogenating 2-butyne-1,4-diol in the presence of a structured catalyst in the absence of a solvent.

Abstract: A junction field effect transistor comprises a semiconductor substrate, a source region formed in the substrate, a drain region formed in the substrate and spaced apart from the source region, and a gate region formed in the substrate. The transistor further comprises a first channel region formed in the substrate and spaced apart from the gate region, and a second channel region formed in the substrate and between the first channel region and the gate region. The second channel region has a higher concentration of doped impurities than the first channel region.