Abstract: The present disclosure relates to methods of feeding animals by providing feed additives that modulate the gut microbiome to improve the health, nutrition, and growth performance. The present disclosure further relates to methods of modulating the microbial species present in the gastrointestinal tract of an animal. Such modulation includes, for example, modulating the level or function of microbial species.
Type:
Grant
Filed:
November 8, 2019
Date of Patent:
February 27, 2024
Assignee:
DSM IP ASSETS B.V.
Inventors:
Stephane Duval, John Michael Geremia, Lisa Ann Laprade, April Waguespack-Levy, Estefania Perez Calvo, Ghislain Schyns, Viviane Verlhac, Joshua Thomas Claypool
Abstract: The present invention relates to the field of microbiology, specifically the field of production of a dairy food product using fermentation and the field of gene transfer by conjugation.
Type:
Grant
Filed:
June 18, 2021
Date of Patent:
February 27, 2024
Assignee:
DSM IP Assets B.V.
Inventors:
Mariya Alexeevna Tarazanova, Thom Huppertz, Herwig Bachmann, Jan Kok, Marke Beerthuyzen
Abstract: The present invention relates a polypeptide having kaurenoic acid 13-hydroxylase activity, which polypeptide comprises an amino acid sequence which, when aligned with a kaurenoic acid 13-hydroxylase comprising the sequence set out in SEQ ID NO: 1 or SEQ ID NO: 3, comprises at least one substitution of an amino acid corresponding to any of amino acids at positions 136, 248, 336 or 403, said positions being defined with reference to SEQ ID NO: 1 or SEQ ID NO: 3 and wherein the polypeptide has one or more modified properties as compared with a reference polypeptide having kaurenoic acid 13-hydroxylase activity. A polypeptide of the invention may be used in a recombinant host for the production of steviol or a steviol glycoside.
Type:
Grant
Filed:
July 21, 2021
Date of Patent:
February 27, 2024
Assignee:
DSM IP ASSETS B.V.
Inventors:
Johannes Gustaaf Ernst Van Leeuwen, Priscilla Zwartjens, Viktor Marius Boer
Abstract: The present invention is directed to a process for making a soluble native rapeseed protein isolate and the soluble native rapeseed protein isolate obtained by the process.
Type:
Grant
Filed:
July 7, 2017
Date of Patent:
February 20, 2024
Assignee:
DSM IP ASSETS B.V.
Inventors:
Johannes Hendrikus Maria Willemsen, Johannes Hendrikus Antonius Jeroen Vermunt, Nienke Nina Hylkema, Gerardus Johannes Franciscus Smolders
Abstract: The present invention is related to a novel enzymatic process for production of retinyl esters, such as in particular retinyl long chain esters, via conversion of retinol, which process includes the use of enzymes having acyltransferase activity. Said process might be used for biotechnological production of vitamin A.
Type:
Grant
Filed:
September 25, 2018
Date of Patent:
February 20, 2024
Assignee:
DSM IP ASSETS B.V.
Inventors:
Nathalie Balch, Paul Blomquist, Reed Doten, Peter Houston, Ethan Lam, Jenna McMahon, Joshua Trueheart, Celine Viarouge
Abstract: The present invention relates to fibers comprising a polyesteramide (PEA) having a chemical formula described by structural formula (IV), wherein m+p varies from 0.9-0.1 and q varies from 0.1 to 0.9; m+p+q=1 whereby m or p could be 0; n is about 5 to about 300; (pref.
Type:
Grant
Filed:
July 21, 2021
Date of Patent:
February 6, 2024
Assignee:
DSM IP ASSETS B.V.
Inventors:
Mirian Hendrika Jacoba Gillisen-Van Der Vight, Jens Christoph Thies, Gueorgui Mihov
Abstract: Preparations of glycan therapeutics, pharmaceutical compositions, dietary supplements and medical foods thereof are provided, and methods of using said glycan therapeutics, e.g. in cancer therapy.
Type:
Grant
Filed:
June 30, 2021
Date of Patent:
January 30, 2024
Assignee:
DSM Nutritional Products, LLC
Inventors:
Geoffrey A. von Maltzahn, Yvonne J. Yamanaka, Jared Silverman, John Miles Milwid, Jacob Rosenblum Rubens, John M. Geremia
Abstract: A method for purifying rebaudioside M, which method comprises: (a) providing a solution comprising rebaudioside M at a concentration of at least about 10 g/L and at a purity of at least about 10% by weight on a dry basis; and (b) crystallizing from the solution a high purity composition comprising rebaudioside M, thereby to purify rebaudioside M.
Type:
Grant
Filed:
August 9, 2017
Date of Patent:
January 23, 2024
Assignee:
DSM IP ASSETS B.V.
Inventors:
Igor Galaev, Robertus Mattheus De Pater
Abstract: The present invention relates to a new delivery system for nutritional ingredients (nutraceuticals). These nutritional ingredients are useful for gut and metabolic health in monogastric animals, especially in humans.
Type:
Grant
Filed:
October 30, 2018
Date of Patent:
January 16, 2024
Assignee:
DSM IP ASSETS B.V.
Inventors:
Elger Funda, Odile Krainz, Robert Steinert
Abstract: Processes for synthesizing new compounds that may usefully be employed in organic synthesis, especially in the synthesis of vitamin A or ?-carotene and derivatives thereof, e.g. canthaxanthin, astaxanthin or zeaxanthin are disclosed. The new compounds are especially useful as intermediates (building blocks) in the synthesis of vitamin A or ?-carotene, preferably vitamin A.
Type:
Grant
Filed:
February 18, 2022
Date of Patent:
December 26, 2023
Assignee:
DSM IP ASSETS B.V.
Inventors:
Raphael Beumer, Werner Bonrath, Marc-André Mueller, Bettina Wüestenberg
Abstract: Processes for preparing a polyamide, a polyamide material obtained by such processes, a nylon salt to be used therein, and processes for making the nylon salt are disclosed. The processes for preparing the polyamide include a direct solid state polymerization process. The salt used herein is a granulate material, prepared by a process, comprising spraying an aqueous solution comprising a diamine and a dicarboxylic acid dissolved in an aqueous medium, or an aqueous slurry comprising a diammonium dicarboxylate salt dispersed in an aqueous medium directly obtained from such an aqueous solution, onto or in a fluidized bed of diammonium dicarboxylate salt particles, while evaporating the aqueous medium, thereby forming a granulate salt material.
Type:
Grant
Filed:
October 28, 2021
Date of Patent:
December 26, 2023
Assignee:
DSM IP ASSETS B.V.
Inventors:
Bas Van Laarhoven, Christiaan Johannes Cornelis Stoelwinder, Mark Helmsing
Abstract: A gluten free native rapeseed protein isolate comprising <10 ppm gliadin and processes to obtain the gluten free native rapeseed protein isolate comprising <10 ppm gliadin.
Type:
Grant
Filed:
December 8, 2016
Date of Patent:
December 19, 2023
Assignee:
DSM IP ASSETS B.V.
Inventors:
Jing Shi, Gerardus Johannes Franciscus Smolders, Johannes Hendrikus Maria Willemsen, Johannes Hendrikus Antonius Jeroen Vermunt, Nienke Nina Hylkema
Abstract: The present invention relates a heteropolysaccharide characterized in that it is substantially composed of the monosaccharides glucose and galactose and rhamnose and N-acetylgalactosamine and a process for the production thereof. The invention further relates to a bacterium capable of producing said heteropolysaccharide and to the use of the heteropolysaccharide and the bacterium for improving the texture of fermented milk products.
Type:
Grant
Filed:
March 10, 2021
Date of Patent:
December 5, 2023
Assignee:
DSM IP ASSETS B.V.
Inventors:
Cornelia Elizabeth Paulina Maljaars, Pim Van Hee
Abstract: A waterproof seal for electrical assemblies wherein an outer sheath of an electrical cable is removed to expose the wires and the insulation is removed from the wires to form a window of exposed electrical conductor, the electrical conductors being maintain apart from each other and contained in a cover that may comprise a connector, an epoxy applied to the electrical conductors to fill in all the space in and around the electrical conductors and the cover to form a waterproof seal that prevents water from wicking past the waterproof seal via an interior of the electrical cable.
Abstract: Methods for providing dietary calcium to livestock and other animals and the compositions for use in providing dietary calcium to livestock are disclosed. Kits to provide the animal with a desired amount of supplemental calcium during normal watering is also disclosed.
Abstract: The invention relates to a thermoplastic composite material comprising a thermoplastic matrix and a fibrous material impregnated with the thermoplastic matrix, wherein the fibrous material comprises carbon fibers with a weight average aspect ratio of length divided by diameter (L/D) of at least 500; the thermoplastic matrix comprises a thermoplastic polymer and a laser absorbing additive.
Type:
Grant
Filed:
December 20, 2018
Date of Patent:
November 21, 2023
Assignee:
DSM IP ASSETS B.V.
Inventors:
Pim Gerard Anton Janssen, Marc Rudolf Stefan Huisman, Giacomo Perfetti
Abstract: The present invention is directed to a method of enhanced production of lipids by limitation of at least two limiting nutrient sources during the fermentation of the lipids producing cells.
Type:
Grant
Filed:
July 18, 2018
Date of Patent:
November 14, 2023
Assignees:
Evonik Operations GmbH, DSM IP Assets B.V.
Inventors:
Adam Burja, James Corona, Jose R. Garcia, Goncalo Oliveira Maia, Horst Priefert, Joachim Windau, Gabriel Závodský
Abstract: The present invention relates to the reduction of oxidative stress, the improvement of the system, the provision of healthy cartilage, as well as the alleviation of pain in ruminants.
Type:
Grant
Filed:
January 23, 2019
Date of Patent:
October 24, 2023
Assignee:
DSM IP ASSETS B.V.
Inventors:
Chris McSweeney, Gonzalo Martinez Fernandez, Stuart Edward Denman, Horst Joachim Paul Peter Schirra