Patents Assigned to E
  • Metallization utilizing a catalyst which is removed or deactivated from undesired surface areas
    Patent number: 4749449
    Abstract: Metallization of nonconductive through holes with pattern plating of a conductive surface is undertaken by removing or deactivating a catalyst from undesired areas prior to electroplating onto the catalyzed surface.
    Type: Grant
    Filed: June 5, 1987
    Date of Patent: June 7, 1988
    Assignee: E. I. Du Pont de Nemours and Company
    Inventor: Kevin D. Scott
  • Process for bimodal chlorination of polyethylene
    Patent number: 4749751
    Abstract: A process is disclosed for producing a blend of chlorinated low density polyethylene and chlorinated high density polyethylene wherein the polyethylenes are placed in a solvent and the temperature raised to a point where the low density polyethylene goes into solution and the high density polyethylene does not go into solution. The low density polyethylene is chlorinated up to the desired level and then the temperature is raised to dissolve the high density polyethylene and chlorination of both polyethylenes is continued to the desired level.
    Type: Grant
    Filed: July 20, 1987
    Date of Patent: June 7, 1988
    Assignee: E. I. Du Pont de Nemours and Company
    Inventors: Royce E. Ennis, Wolfgang Honsberg
  • 7-oxabicycloheptane substituted amino prostaglandin analogs
    Patent number: 4749715
    Abstract: 7-Oxabicycloheptane substituted amino prostaglandin analogs are provided having the structural formula ##STR1## wherein n is 1 to 5; R.sup.1 is CO.sub.2 H, CO.sub.2 lower alkyl or ##STR2## and R.sup.2 is ##STR3## wherein R.sup.3 is lower alkyl, aralkyl, --NHalkyl or --NHaryl, or R.sup.2 is ##STR4## wherein q is 1 to 12, and R.sup.4 is lower alkyl, lower alkenyl, lower alkynyl, aryl, arylalkyl, lower alkoxy, aryloxy, arylalkyloxy, amino, alkylamino arylamino, arylalkylamino, lower alkyl-S--, aryl-S--, arylalkyl-S--, ##STR5## (wherein n' is 0, 1 or 2), alkylaminoalkyl, arylaminoalkyl, arylalkylaminoalkyl, alkoxyalkyl, aryloxyalkyl or arylalkoxyalkyl.The compounds are cardiovascular agents useful, for example, in the treatment of thrombotic disease and are useful in the preparation of radiolabelled analogs.
    Type: Grant
    Filed: March 2, 1987
    Date of Patent: June 7, 1988
    Assignee: E. R. Squibb & Sons, Inc.
    Inventor: Steven E. Hall
  • Diamino ketones and alcohols as analgesic agents
    Patent number: 4749792
    Abstract: Analgesic activity is exhibited by compounds having the formula ##STR1## and pharmaceutically acceptable salts thereof wherein R.sub.1, R.sub.2 and R.sub.4 are each independently hydrogen, alkyl, carboxyalkyl, halosubstituted alkyl, hydroxyalkyl, aminoalkyl, mercaptoalkyl, alkylthioalkyl, (cycloalkyl)alkyl, (heteroaryl)alkyl, arylalkyl, carbamoylalkyl, guanidinylalkyl, or heteroaryl, and R.sub.3 is hydroxymethylene or carbonyl.
    Type: Grant
    Filed: September 26, 1984
    Date of Patent: June 7, 1988
    Assignee: E. R. Squibb & Sons, Inc.
    Inventors: Sesha I. Natarajan, Eric M. Gordon
  • Acrylic amphoteric polymers
    Patent number: 4749762
    Abstract: Amphoteric polymers prepared by polymerization of (a) acrylic acid, (b) N,N-dimethyl- orN,N-diethylaminoethyl methacrylate and, optionally, (c) esters of methacrylic or acrylic acid prepared by (i) emulsion polymerization of (b), (c) and the methyl ester of (a), followed by basic hydrolysis, or (ii) polymerization of (a), (b) and (c) in the presence of a strong acid, and photographic emulsions comprised of said polymers in which the molar ratio of (a) to (b) is at least 2 to 1 and a silver halide.
    Type: Grant
    Filed: May 12, 1982
    Date of Patent: June 7, 1988
    Assignee: E. I. Du Pont de Nemours and Company
    Inventor: Robert P. Foss
  • Microbiological decomposition of chlorinated aliphatic hydrocarbons
    Patent number: 4749491
    Abstract: An aerobic method for in situ treatment of water and soil which has been contaminated with chlorinated hydrocarbons. The aerobic method involves feeding an aqueous solution of an oxygen source and nutrients without the addition of a flammable carbon source such as propane or methane gas to a contaminated area to cause the indigenous microorganisms to grow consuming the contaminants.
    Type: Grant
    Filed: July 23, 1987
    Date of Patent: June 7, 1988
    Assignee: E. I. Du Pont de Nemours and Company
    Inventors: Bernard C. Lawes, Carolann D. Litchfield
  • Aminocarbonyl renin inhibitors
    Patent number: 4749781
    Abstract: Compounds of the formula ##STR1## are disclosed. These compounds intervene in the conversion of angiotensinogen to angiotensin II by inhibiting renin and thus are useful as antihypertensive agents.
    Type: Grant
    Filed: September 19, 1986
    Date of Patent: June 7, 1988
    Assignee: E. R. Squibb & Sons, Inc.
    Inventor: Eric M. Gordon
  • Multilayer reverse osmosis membrane in which one layer is poly-meta-phenylene tetrahydrofuran-2,3,4,5-tetracarboxamide
    Patent number: 4749488
    Abstract: A multilayer membrane for performing reverse osmosis is disclosed. The membrane comprises a porous support and interfacially polymerized thereon a superposed layer of poly meta-phenylene tetrahydrofuran-2,3,4,5-tetracarboxamide in which up to 50 mole % of the tetrahydrofuran-2,3,4,5-tetracarboxamide units have been replaced with isophthalamide or terephthalamide units. The preferred material for forming the support is a polysulfone.
    Type: Grant
    Filed: October 8, 1987
    Date of Patent: June 7, 1988
    Assignee: E. I. Du Pont De Nemours and Company
    Inventors: Samuel D. Arthur, Sherman A. Sundet
  • Phosphate cement including fly ash for high-strength concrete-like products
    Patent number: 4749413
    Abstract: Rapid-setting compositions based on MgO and Al(H.sub.2 PO.sub.4).sub.3 and having at least a ten-minute working time, and thus suitable for mortars and road patching, form concrete-like products having increased compressive strength when fly ash is present. Fly ash reacts with aluminum phosphate to form a cementitous composition whose compressive strength is the cause of the strength increase observed in the MgO/Al(H.sub.2 PO.sub.4).sub.3 reaction product.
    Type: Grant
    Filed: October 24, 1986
    Date of Patent: June 7, 1988
    Assignee: E. I. Du Pont de Nemours and Company
    Inventor: Ernst A. Tomic
  • Antiinflammatory and/or analgesic 5-alkylthiophenes
    Patent number: 4749712
    Abstract: 5-Alkyl-2,3-diarylthiophenes, such as 5-(1,1-dimethylethyl)-2,3-bis(4-methoxyphenyl)thiophene, 5-(1-methylpropyl)-2,3-bis(4-methoxyphenyl)thiophene and 5-cyclohexyl-2,3-bis(4-methoxyphenyl)thiophene, are useful in the treatment of inflammation and/or pain.
    Type: Grant
    Filed: December 5, 1984
    Date of Patent: June 7, 1988
    Assignee: E. I. Du Pont de Nemours and Company
    Inventor: Stephen B. Haber
  • Aryl substituted aminomethyl benzene derivatives having antiarrhythmic utility
    Patent number: 4748184
    Abstract: The present invention relates to new compounds of the formula ##STR1## wherein X is ##STR2## wherein R.sub.1 is hydrogen, lower alkyl, phenyl, benzyl, cinnamoyl, thiophene, furan, pyrrole, imidazole, pyrazole oxazole or thiazole; W is hydrogen or hydroxy; (Y).sub.A is positioned ortho to W and is an aminoloweralkyl having the formula --CH.sub.2 NR.sub.2 R.sub.3 where R.sub.2 and R.sub.3 are the same or different and may be lower alkyl or R.sub.2 and R.sub.3 may together with N form a pyrrolidine, piperidine or azepine ring, and A is 2; n and m are independently from 0 to 5; and R is straight or branched C.sub.1 -C.sub.10 alkyl, straight or branched C.sub.3 -C.sub.10 cycloalkyl, straight or branched C.sub.2 -C.sub.4 alkenyl or straight or branched C.sub.2 -C.sub.4 alkynyl, or a pharmaceutically acceptable salt thereof.These compounds are useful in the treatment of various cardiac arrhythmias.
    Type: Grant
    Filed: December 27, 1985
    Date of Patent: May 31, 1988
    Assignee: E. I. Du Pont de Nemours and Company
    Inventors: David M. Stout, William L. Matier, Lawrence A. Black
  • 4-hydroxycoumarin derivatives
    Patent number: 4748185
    Abstract: The invention provides 4-hydroxycoumarin compounds of general formula ##STR1## wherein R.sup.1 and R.sup.2 are independently selected from hydrogen and halogen atoms and R represents a group of formula ##STR2## wherein one of n and n' is O, the other being 0 or 1, D represents a moiety --O--, --(CH.sub.2).sub.m -- or --O(CH.sub.2).sub.m -- where m is 1 or 2 and X represents a substituent selected from hydrogen, halogen, CN, CF.sub.3, OCF.sub.3, C.sub.1-6 alkyl and C.sub.1-6 alkoxy moieties, provided that when n is 1 and D is --OCH.sub.2 --, X may additionally represent a phenyl group, optionally substituted in the 4-position by a substituent selected from halogen, CN, CF.sub.3, OCF.sub.3, C.sub.1-6 alkyl and C.sub.1-6 alkoxy moieties; their preparation and their use as rodenticides.
    Type: Grant
    Filed: December 16, 1986
    Date of Patent: May 31, 1988
    Assignee: E. I. Du Pont de Nemours and Company
    Inventors: Ian D. Entwistle, Peter Boehm
  • Compartmentalized cell-culture device and method
    Patent number: 4748124
    Abstract: A closed, cell culture device constructed using a first and second sheet of gas permeable, liquid-impermeable material. A third sheet of a material selectively permeable to a class of molecules sandwiched between the first and second sheets, all of the sheets being formed such that the first and third sheets define a first closed compartment and the second and third sheets define a second closed compartment, each compartment having an access port.
    Type: Grant
    Filed: October 30, 1984
    Date of Patent: May 31, 1988
    Assignee: E. I. Du Pont de Nemours and Company
    Inventor: Erwin A. Vogler
  • Herbicidal pyrazole sulfonamides
    Patent number: 4747870
    Abstract: This invention relates to certain pyrazole sulfonylurea herbicidal compounds, agriculturally suitable compositions thereof and a method of their use.
    Type: Grant
    Filed: March 13, 1987
    Date of Patent: May 31, 1988
    Assignee: E. I. Du Pont de Nemours and Company
    Inventor: Barry A. Wexler
  • Spunlaced nonwoven protective fabric
    Patent number: 4748065
    Abstract: A flame resistant and noxious chemical adsorbent, flexible, creped fabric suited for use as a protective garment is disclosed. The fabric is spunlaced and nonwoven and is impregnated with adsorbent carbonized particles.
    Type: Grant
    Filed: August 13, 1986
    Date of Patent: May 31, 1988
    Assignee: E. I. Du Pont de Nemours and Company
    Inventor: Murty S. S. R. Tanikella
  • Method for forming amphotericin B crystals in fermentation broth
    Patent number: 4748117
    Abstract: A new method is provided for forming crystals of amphotericin B directly in fermentation broth which crystals are easily separable without use of costly solvent extraction techniques which method includes a direct microbial cell autolysis step to induce crystal formation.
    Type: Grant
    Filed: April 16, 1986
    Date of Patent: May 31, 1988
    Assignee: E. R. Squibb & Sons, Inc.
    Inventors: Raphael Y. Ko, Laszlo J. Szarka
  • Heat exchanger for liquids
    Patent number: 4747449
    Abstract: A heat exchanger for cooling liquid food products includes an elongated shell through which a refrigerant can be recirculated and hollow tubes extending within the shell interior in parallel spaced relation between its opposite ends for carrying the liquid food product. A pair of electropolished stainless steel tube sheets are attached to opposite ends of the shell and have openings defined therethrough. The tube sheets support the hollow tubes at their opposite ends in communication with the openings. Also, a pair of electropolished stainless steel end bonnets are releasably attached to the tube sheets and mounted for pivotal movement between opened and closed positions relative thereto. The end bonnets have flow return pockets defined therein which communicate pairs of openings with one another independently of others of the openings.
    Type: Grant
    Filed: July 25, 1986
    Date of Patent: May 31, 1988
    Assignee: E. L. Nickell Co., Inc.
    Inventor: Shelby W. Nickell
  • Pre-filled syringe
    Patent number: 4747829
    Abstract: A pre-filled syringe is provided with a retractile needle. The needle end of a syringe is enclosed in a sterile chamber within a casing sealed by a cap with a break-off tip. The barrel of the syringe is movable within the casing from a remote pre-injection position to a forward injection position and back again. When the barrel is moved forward a first end of the needle passes through the opening of the cap and then the opposite end comes in contact with the injectant. When the barrel is withdrawn to a pre-injection position, the needle is retracted within the casing and is prevented from re-entering the opening in the cap.
    Type: Grant
    Filed: January 21, 1987
    Date of Patent: May 31, 1988
    Assignee: E. R. Squibb & Sons, Inc.
    Inventors: Jean-Louis Jacob, Gaetan Sanschagrin, Jean Thibodeau, France Guay
  • Benzazepine derivatives
    Patent number: 4748239
    Abstract: Vasodilating activity is exhibited by compounds having the formula ##STR1## and pharmaceutically acceptable salts thereof.
    Type: Grant
    Filed: April 24, 1987
    Date of Patent: May 31, 1988
    Assignee: E. R. Squibb & Sons, Inc.
    Inventors: David Floyd, John Krapcho
  • Shipping bag for particulate material
    Patent number: D296078
    Type: Grant
    Filed: January 14, 1985
    Date of Patent: June 7, 1988
    Assignee: E. I. Du Pont de Nemours and Company
    Inventor: Richard B. Nelson