Abstract: Provided are improved methods for identifying the substrate recognition specificity or activity of a protease, convertase (sortase), or kinase. In some embodiments, methods are provided for identifying the endogenous protease or convertase cleaving patterns (e.g., “cleaveOme”) inside the secretory pathway of a living cell. Select embodiments involve aspects of yeast endoplasmic reticulum sequestration screening and next generation sequencing. Methods of producing polypeptides in Kex2 knockout yeast are also provided.

Abstract: ISEs comprising a substrate layer; a carbon nanotube layer disposed on the substrate layer; a conductive metal layer on a portion of the carbon nanotube layer; a conductive polymer disposed on the portion; and an ion-selective membrane disposed on the conductive polymer and methods of making them are provided. A system is also provided for detecting a plurality of analyte ions in a sample comprising a housing; a plurality of ISEs associated with the housing, each electrode comprising an ion-selective membrane to a different analyte ion; a reference electrode associated with the housing; a fluid sample receptacle associated with the housing and in fluid communication with the plurality of ion-selective electrodes and reference electrode.

Abstract: Processing an image includes acquiring, by the image processing apparatus, a target image, extracting a shape of a target object included in the target image, determining a category including the target object based on the extracted shape, and storing the target image by mapping the target image with additional information including at least one keyword related to the category.

Abstract: Patterning methods for forming patterned device substrates are provided. Also provided are devices made using the methods. The methods utilize photoresist features have re-entrant profiles to form a secondary metal hard mask that can be used to pattern an underlying device substrate.

Abstract: An audio metadata providing apparatus and method and a multichannel audio data playback apparatus and method to support a dynamic format conversion are provided. Dynamic format conversion information may include information about a plurality of format conversion schemes that are used to convert a first format set by a writer of multichannel audio data into a second format that is based on a playback environment of the multichannel audio data and that are set for each of playback periods of the multichannel audio data. The audio metadata providing apparatus may provide audio metadata including the dynamic format conversion information. The multichannel audio data playback apparatus may identify the dynamic format conversion information from the audio metadata, may convert the first format of the multichannel audio data into the second format based on the identified dynamic format conversion information, and may play back the multichannel audio data with the second format.

Abstract: A method of obtaining a focus term by using a periodicity of the focus term is provided. The focus term may be used in a plurality of operation processes for processing image data.

Abstract: A microchip includes a first chamber and second chamber formed to a predetermined depth in a member made of polydimethylsiloxane (PDMS); and a channel (microchannel) connecting the first chamber to the second chamber. These components mimic in vivo organs which produce by selecting capacitated motile sperm from semen and causing the selected sperm to meet mature oocyte, and these components are capable of effectively producing motile capacitated good-quality sperms from sperms ejaculated outside the body.

Abstract: A mobile visible light communication (VLC) receiver and associated method of use which overcomes the detrimental effects of the time-varying inter-symbol interference (ISI) due to the VLC receiver's high acceptance angle and vibration in the structure utilizing an optimal multiple-symbol detection (MSD) module and a decision feedback affine projection algorithm (DF-APA) module.

Abstract: A sensor including a layer of amorphous selenium (a-Se) and at least one charge blocking layer is formed by depositing the charge blocking layer over a substrate prior to depositing the amorphous selenium, enabling the charge blocking layer to be formed at elevated temperatures. Such a process is not limited by the crystallization temperature of a-Se, resulting in the formation of an efficient charge blocking layer, which enables improved signal amplification of the resulting device. The sensor can be fabricated by forming first and second amorphous selenium layers over separate substrates, and then fusing the a-Se layers at a relatively low temperature.

Abstract: The scope of this invention is to disclose the method of foaming a superior impact mitigation material, namely semi-closed cell hybrid polyurea foam, using scalable manufacturing process that is geometry-independent and allows for greater control of the resulting foam properties. while the process discussed herein, can be easily used to make complex geometries (e.g., padding foam for helmets, outsoles for walking and running shoes, body armors or other protection applications.

Abstract: A base station for transmitting and receiving signals in a wireless communication system is provided. The base station includes a transceiver, and at least one processor configured to obtain reception antenna weights for the base station including an array of a plurality of antennas, and transmission antenna weights for at least one user equipment (UE), convert signals received from the at least one UE through a plurality of reception paths, into beam-domain signals, based on the transmission antenna weights and the reception antenna weights, combine the converted beam-domain signals by applying predefined combining weights to the converted beam-domain signals, and obtain data from the combined signals.

Abstract: Provided herein are recombinant adeno-associated virus (rAAV) nucleic acid vectors that comprise one or more modifications within at least one inverted terminal repeat (ITR) region. Exemplary modifications include ITR sequences comprising a glucocorticoid responsive element and/or a transcription factor binding site. Also provided are plasmids, libraries, rAAV particles, compositions, kits, and methods related to such vectors.

Abstract: A method for identifying non-IP cameras is disclosed. The method includes receiving name of an organization by one or more processors, performing an internet search via a script for the name associated with the organization by the one or more processors, thereby generating a plurality of website Hypertext Markup Language (HTML) listings, and parsing each of the generated HTMLs to identify uniform resource locator (URL) for a plurality of cameras by the one or more processors; analyzing each of the HTMLs to determine how metadata of each of the plurality of cameras is presented in the HTML by the one or more processors; determining physical location of each of the plurality of cameras by analyzing the associated metadata; and adding the camera of the plurality to a database of cameras.

Abstract: The present disclosure relates to a phase change composite and a heat spreader including the same, and more particularly, to a phase change composite having improved cooling performance by being formed in a layer-by-layer structure composed of a material having high thermal conductivity and a phase change material. According to the present disclosure, by repeatedly laminating thermal conductive layers and phase change material unit layers, thermal conductivity in the horizontal direction may be dramatically improved. In addition, due to a high volume percentage of a phase change material, a heat spreader with a large heat capacity may be provided.

Abstract: Vectors and methods are disclosed for immortalizing mammalian cells by co-expression of v-raf and v-myc proteins. A replication-defective viral vector is used for improved safety. The vector comprises an optional marker gene, and is especially useful for producing an immortalized macrophage by a method that involves contacting the vector with a monocyte, proliferatively growing the monocyte, growing the monocytic cell on a solid surface, and then growing the monocytic cell on a porous surface. An immortalized macrophage is also disclosed.

Abstract: This disclosure relates to variant AAV6 particles engineered to escape host neutralizing antibodies but retain or improve transduction efficiency, and their use as gene delivery vehicles.

Abstract: The invention provides a method for reducing oxidative damage in a mammal, a removed organ, or a cell in need thereof The method comprises administering an effective amount of an aromatic cationic peptide. The aromatic cationic peptide has (a) at least one net positive charge; (b) a minimum of three amino acids; (c) a maximum of about twenty amino acids, (d) a relationship between the minimum number of net positive charges (pm) and the total number of amino acid residues (r) wherein 3 pm is the largest number that is less than or equal to r+1; (e) a relationship between the minimum number of aromatic groups (a) and the total number of net positive charges (pt) wherein 3a or 2a is the largest number that is less than or equal to pt+1, except that when a is 1, pt may also be 1; and (f) at least one tyrosine or tryptophan amino acid.

Abstract: Disclosed is method for preparation of a starch phosphate using phytate. The method enables the preparation of a starch phosphate with improved physical properties such as high transparency, solubility, swelling power, and storage stability by the phosphorylation of a starch using naturally occurring phytate rather than using a synthetic chemical. Due to these advantages, the starch phosphate is expected to replace conventional chemically modified starches. In addition, the method enables the preparation of a starch phosphate based on a simple modification. The use of the starch phosphate greatly contributes to improvements in the quality and storage stability of various starchy foods. Therefore, the starch phosphate is expected to find application in the food industry, including starchy foods.

Abstract: Disclosed is a floating gate memristor device comprising: a substrate; a floating gate disposed on the substrate; an insulating layer covering the floating gate; a first electrode including a plurality of control terminals disposed on the insulating layer and spaced apart from each other, wherein the plurality of control terminals vertically overlap the floating gate; a second electrode spaced away from the first electrode, wherein a ground voltage is applied to the second electrode; and a third electrode disposed on the substrate and electrically connected to the floating gate.

Abstract: The present invention relates to glycyrrhizin-glycol chitosan conjugate-coated nanoparticles, islet cells, prepared using same, for transplantation, and an MRI imaging composition comprising same. If transplanted, the islet cells comprising the nanoparticles can suppress a post-transplantation immune response. The present invention can provide islet cells for transplantation that can be transplanted to a certain region by magnetic force induction and can be tracked by MRI.