Abstract: Disclosed are a 4D printing method using thermal anisotropy and thermal transformation, and the resulting product. The method includes (a) artificially planning transverse printing paths and longitudinal printing paths on a specimen to impose a thermal anisotropy to the specimen, (b) sequentially and alternately forming transversely printed layers and longitudinally printed layers on the specimen by printing a thermoplastic polymer in transverse and longitudinal directions to build a 3D printed product, (c) heating the 3D printed product so that the 3D printed product thermally transforms in a specific direction, and (d) controlling heating time to obtain a 4D printed product having a desired final shape which is formed through the transformation of the 3D printed product over the heating time.

Abstract: The present invention is directed to a sensor having continuous and discontinuous regions of conductive metallic nanoparticles capped with an organic coating which enables the detection of volatile organic compounds and/or water vapor. Continuous regions may exhibit a positive response upon exposure to volatile organic compounds and to water vapor, while discontinuous regions exhibit a positive response upon exposure to volatile organic compounds and a negative response upon exposure to water vapor.

Abstract: The present disclosure provides methods and compositions for preventing or treating MV-induced or disuse-induced skeletal muscle infirmities in a mammalian subject. The methods further include administering to the subject an effective amount of an aromatic-cationic peptide.

Abstract: A slurry for electrostatic spray deposition and method for forming a coating film using the same are provided. The slurry comprises a solvent, a first polymer dissolved in the solvent, and polymer particles containing a second polymer and dispersed in the solvent.

Abstract: A method of selectively broadcasting a message to a client by a server without knowing the client's internet protocol (IP) address includes receiving video feeds of an area of interest from one or more cameras, performing target recognition and tracking on one or more targets, including position of the one or more targets, extracting target-specific context parameters from the one or more recognized and tracked targets, encoding the target-specific context parameters into a header, thereby generating a context address for the one or more targets, appending the context address to a message for the one or more targets from a predetermined set of messages based on the position of the one or more targets, thereby generating one or more packets of information, and broadcasting the one or more packets wirelessly to one or more client mobile devices each associated with the one or more targets.

Abstract: A sensor for measuring rate of rotation is disclosed which includes a disk resonator, an anchor coupled to the disk resonator and further coupled to a substrate, and an optical waveguide wrapping around at least a portion of the perimeter of the disk resonator, the optical waveguide having an input end and an output end, wherein the disk resonator is configured to expand radially when subject to a rotational input, and wherein said radial expansion is adapted to cause a change in an optical signal passing through the optical waveguide.

Abstract: A new solvent-based method is presented for making low-cost composite graphite electrodes containing a thermoplastic binder. The electrodes, termed thermoplastic electrodes (TPEs), are easy to fabricate and pattern, give excellent electrochemical performance, and have high conductivity (1500 S m?1). The thermoplastic binder enables the electrodes to be hot embossed, molded, templated, and/or cut with a CO2 laser into a variety of intricate patterns. These electrodes show a marked improvement in peak current, peak separation, and resistance to charge transfer over traditional carbon electrodes. The impact of electrode composition, surface treatment (sanding, polishing, plasma treatment), and graphite source were found to impact fabrication, patterning, conductivity, and electrochemical performance. Under optimized conditions, electrodes generated responses similar to more expensive and difficult to fabricate graphene and highly oriented pyrolytic graphite electrodes.

Abstract: Provided is an electronic signature technique depending on a diametrically different algorithm from the existing asymmetric key infrastructure electronic signature technique which generates predetermined syndrome data based on a message to be transmitted a data receiving device and then detects an error vector for an electronic signature from the syndrome data by using a parity check matrix and then generates an electronic signature value based on an error vector for the electronic signature and transmits the generated electronic signature value to the data receiving device.

Abstract: The present invention relates to a gingerol derivative having inhibitory activity against biofilm formation and a pharmaceutical composition for preventing or treating infections caused by biofilms including the gingerol derivative as an active ingredient. The gingerol derivative of the present invention exhibits significantly improved binding affinity for LasR and inhibitory activity against biofilm formation. Therefore, the gingerol derivative of the present invention can act on various membrane surfaces where biofilms tend to form and can effectively inhibit the formation of the corresponding biofilms. In addition, the use of the pharmaceutical composition according to the present invention can fundamentally prevent or treat a variety of infections caused by biofilms due to the presence of the gingerol derivative in the pharmaceutical composition.

Abstract: This document relates to materials and methods for identifying and monitoring immunoglobulin J chains in a sample, such as a biological sample, using mass spectrometry techniques.

Abstract: This document provides methods and materials related to treating cancer (e.g., skin cancer). For example, methods and materials relating to the use of a composition containing albumin-containing nanoparticle/antibody complexes (e.g., Abraxane®/anti-VEGF polypeptide antibody complexes) to treat cancer (e.g., skin cancer) are provided.

Abstract: A seed coating composition comprising a mixture of a fungal root endophyte isolated from a root of the plant found in low-nutrient, drought-stressed or multiply-stressed conditions and a carrier medium for application of said composition to a target seed, wherein the endophyte is characterised in having a nuclear ribosomal internal transcribed spacer (nr ITS) with at least a 90% sequence identity to any one of SEQ ID NOs: 3 to 15.

Abstract: Conjugates are described herein where CCK2R targeting ligands are attached to an active moiety, such as therapeutic agent or an imaging agent, through a linker. The conjugates can be used in the detection, diagnosis, imaging and treatment of cancer.

Abstract: A method for preparing a three-dimensional graphene structure, and an energy storage device are provided, the method including forming a graphene precursor by heating a carbohydrate and a gas generator, forming a graphene structure having a cavity therein by carbonizing the graphene precursor, and forming nanopores in the graphene structure, wherein the nanopores pass through an outer surface and an inner surface of the graphene structure, and are connected with the cavity.

Abstract: Embodiments of the present disclosure provide for magnetic particle conjugates, methods of making the magnetic particle conjugates, methods of using magnetic particle conjugates, micelles (also referred to as a “magnetic composite nanocarrier” (MC-NC)), methods of making micelles, methods of using micelles, and the like.

Abstract: Human pluripotent stem cells (hPSCs) are promising cell source to produce therapeutic endocrine cells for diabetes treatment. A gel solution made by decellularized tissue-specific extracellular matrix (dpECM) significantly promotes three-dimensional (3D) islet-like organogenesis during induced hPSC differentiation into endocrine lineages. Islet organoids are self-organized even in a two-dimensional (2D) culture mode. Cells derived from hPSCs differentiated on such ECM coated substrates exhibit similar cellular composition to native pancreatic islets. These cells express islet signature markers insulin, PDX-1, C-peptide, MafA, glucagon, somatostatin, and pancreatic polypeptide, and secrete more insulin in response to glucose level compared to a traditional matrix substrate (Matrigel). The dpECM facilitates generating more C-peptide+/glucagon? cells rather than C-peptide+/glucagon+ cells. Remarkably, dpECM also facilitated intra-organoid vascularity by generating endothelial cells and pericytes.

Abstract: Apparatuses, systems, and methods for providing load disaggregation, remote monitoring, and controlling a plurality of loads are provided. The apparatus may include a universal embedded metering and control system (UEMCS) and a universal storage and renewable energy interface (USREI). The UEMCS may include a main device engine, a communication module coupled to the main device engine, a multiplexer coupled to the main device engine, a plurality of current sensors coupled to the multiplexer, and at least one voltage sensor coupled to the main device engine. The USREI may be coupleable to at least one of the plurality of current sensors, coupled to at least one renewable energy source, and configured to provide energy output by the at least one renewable energy source to the UEMCS for output to at least one of the plurality of loads.

Abstract: A system and method for estimating a physiological parameter from data acquired with a medical imaging system includes acquiring data with the medical imaging system. A physiological parameter is estimated from the acquired data using an iterative estimation in which a model of the medical imaging system is decoupled from a physics-based model of the acquired data.

Abstract: Provided are imaging agents comprising a compound of Formula I, or a pharmaceutically acceptable salt thereof, and methods of their use.

Abstract: A method for the rapid and controlled synthesis of mixed metal oxide nanoparticles using relatively low temperature plasma oxidation of liquid droplets of predetermined mixed metal precursors is disclosed. The resulting nanoparticles reflect the metal precursor stoichiometries and the mixed metal oxide's metastable phase can be controlled. The synthesis of mixed transition metal oxide comprising binary metal oxides, ternary mixed metal oxides, quaternary mixed metal oxides and pentanary mixed metal oxides are demonstrated herein.