Abstract: The invention generally relates to conducting reactions in Leidenfrost-levitated droplets.

Abstract: The delivery system may include, for example, an outer catheter having a distal tip and an inner support member, such as an inner catheter, disposed within the outer catheter. The inner support member includes an anchor member adjacent a distal tip of the inner support member and a support portion axially inward of the anchor member. The support portion is configured for supporting an implantable device thereon. A diameter of the anchor member corresponds to a diameter of a portion of a vessel in which the anchor member is to be disposed. The anchor member is configured to be lodged in the portion of the vessel to locate an intended position of the anchor member and to prevent movement of the inner support member relative to the vessel during release of the implantable device.

Abstract: A wearable paper-based platform with simultaneous passive and active feedback for monitoring perspiration is provided. The sensor platform comprises two modules: a disposable wicking-based sweat collection patch with discrete colorimetric feedback, and a reusable electronic detachable module for active feedback. The disposable patch comprises a hygroscopic wicking material laminated between two polymeric films. The wicking material is patterned with a radial finger design that offers discretized visual readout of the sensor. The active module attaches to the film and alerts the user when the film collects a pre-determined volume of sweat. The multi-feedback system allows high-performance athletes who value objective quantification of perspiration to better assess their sweat loss during physical activities.

Abstract: The present disclosure relates to a pharmaceutical composition for preventing or treating neurodegenerative diseases, the pharmaceutical composition including a graphene nanostructure as an active ingredient.

Abstract: Optoelectronic devices that use very thin single-crystalline inorganic semiconductor films as phonon-absorbing layers in combination with non-lattice optical cavities are provided.

Abstract: Described herein are compositions of antibodies and carrier proteins and methods of making and using the same, in particular, as a cancer therapeutic. Also described are lyophilized compositions of antibodies and carrier proteins and methods of making and using the same, in particular, as a cancer therapeutic.

Abstract: A distal radioulnar joint prosthesis for replacing the distal radioulnar joint and a method for its implantation is provided. Such a device includes an ulnar component, a radial component, and a motion liner. The ulnar component includes a stem, a collar, and a shell. The radial component includes a hemispherical ball and plate. The hemispherical ball of the radial component is secured with the radial plate and articulates with the ulnar shell via the motion liner. The prosthesis is designed to more accurately replicate the biomechanics of the distal wrist than currently used implants.

Abstract: The present disclosure relates to a novel method of laser-based fabrication of a carbon nanotube (CNT)-metal composite on a flexible substrate, and the fabricated CNT-metal composite that is bonded with the flexible substrate, and that has a high electrical conductivity, and that has a longer bending-fatigue life than the laser-sintered metal of the same type without CNTs onto the flexible substrate.

Abstract: Compounds and compositions that can modulate mitochondrial function in neuronal cells are provided herein, as are methods for using the compounds and compositions to treat or prevent conditions such as Alzheimer's disease. For example, compounds of Formula I, compositions containing the compounds, and methods for using the compounds and compositions are provided herein: wherein X is absent, CH2, or C(O); R1 is H, OH, CN, NO2, halo, C1-3 alkyl, C1-3 haloalkyl, C1-3 alkoxy, C1-3 haloalkoxy, C3-7 cycloalkyl, amino, C1-3 alkylamino, or di(C1-3 alkyl)amino; R2 is H or C1-6 alkyl; R3 is H, C1-6 alkyl, —C(O)(C1-3 alkyl), or —C(O)O(C1-3 alkyl); R4 is C3-10 cycloalkyl, C6-10 aryl, 5-10 membered heteroaryl, or 5-10 membered heterocycloalkyl, each optionally substituted by 1, 2, 3, or 4 independently selected R5 groups; and R5 is OH, CN, NO2, halo, C1-3 alkyl, C1-3 haloalkyl, C1-3 alkoxy, C1-3 haloalkoxy, C3-7 cycloalkyl, amino, C1-3 alkylamino, or di(C1-3 alkyl)amino.

Abstract: Disclosed herein are inhibitors of PU.1. The inhibitors are useful for treating disorders associated with abnormal PU.1 levels and function.

Abstract: Various examples related to automatically composing universal filters are presented. In one example, among others, a system includes processing circuitry that can organize data received by the system into clusters or quasi-orthogonal regions, which are organized based upon a centroid threshold distance. The data can be organized by applying a cluster and retain operation, a cluster and merge operation or a split and retain operation. The system can then determine filter weights based at least in part upon centers of the clusters; update a content addressable filter bank (CAFB) based upon the filter weights; and filter subsequently received data based upon the CAFB. In another example, a method includes receiving and organizing initial data into clusters or quasi-orthogonal regions; determining filter weights based at least in part upon centers of the clusters; updating a CAFB based upon the filter weights; and receiving and filtering subsequent data based upon the CAFB.

Abstract: An optical device, wherein the optical device includes a dielectric layer over a mirror layer. The optical device further includes a plurality of plasmonic nanoparticles over the dielectric layer. Additionally, the optical device includes a protective layer over the plurality of plasmonic nanoparticles.

Abstract: The present invention generally relates to carbon monoxide releasing compounds and compositions, and their use as carbon monoxide prodrugs.

Abstract: An oral dosage form comprising a single dose of 25-hydroxy-vitamin D3 sufficient to elevate the serum level in a human to a concentration in the range of 30 ng/ml to 200 ng/ml for at least 7 days and a pharmaceutically suitable oral carrier system, wherein subsequent single doses at least every 7 days are sufficient to sustain the serum level in a human to a concentration in the range of 30 ng/ml to 200 ng/ml at steady-state pharmacokinetics is disclosed.

Abstract: The present invention relates to a composition or cell therapeutic agent for preventing or treating liver fibrosis, containing an exosome or exosome-derived ribonucleic acid. The exosome or ribonucleic acid derived therefrom, of the present invention, has effects of inhibiting activities of hepatic stellate cells and Kupffer cells and reducing the expression of ?-SMA and inhibits the progression of liver fibrosis by inhibiting the deposition of collagen, thereby being effectively usable as a cell therapeutic agent for the prevention or treatment of liver fibrosis.

Abstract: This document relates to methods and materials for providing stimulation or ablation to the stellate ganglion. For example, this document relates to methods and devices for providing stimulation or ablation to the stellate ganglion to modify blood pressure.

Abstract: The 360-degree image producing method according to an embodiment of the present invention includes: an information receiving step of receiving 360-degree image producing information including a plurality of camera images, pose information, position information, depth information, a camera model, and a 360-degree model; a target selecting step of selecting a depth information point corresponding to a target pixel included in the 360-degree image among a plurality of points included in the depth information, using the position information, the 360-degree model and the depth information; an image pixel value acquiring step of acquiring a pixel value of a pixel of a camera image corresponding to the depth information point among the plurality of camera images; and a target pixel constructing step of constructing a pixel value of the target pixel.

Abstract: Systems and methods for diagnosing prostate cancer. Image sets (e.g., MRI collected at one or more b-values) and biological values (e.g., prostate specific antigen (PSA)) have features extracted and integrated to produce a diagnosis of prostate cancer. The image sets are analyzed primarily in three steps: (1) segmentation, (2) feature extraction, smoothing, and normalization, and (3) classification. The biological values are analyzed primarily in two steps: (1) feature extraction and (2) classification. Each analysis results in diagnostic probabilities, which are then combined to pass through an additional classification stage. The end result is a more accurate diagnosis of prostate cancer.

Abstract: A sensing device that may include a substrate; a single-ended SPAD; first electrical components; second electrical components; and capacitors. The SPAD, the first electrical components and the second electrical components are formed on the substrate. The SPAD and the first electrical components belong to a high voltage domain of the sensing device. The high voltage domain is configured to receive a high supply voltage that exceeds a breakdown voltage of the SPAD. The second electrical components belong to a low voltage domain of the sensing device. The capacitors are coupled between the low voltage domain and the high voltage domain. The first electrical components and the second electrical components belong to an electrical circuit that is configured to perform quenching of the SPAD.

Abstract: A semiconductor building block is disclosed which includes a plurality of logic gates, each having at least one P-channel device, at least one N-channel device, and a current controller controlling current for each of the plurality of logic gate having a voltage source input (vdd), a ground input (vss), a first input current (ibiasn) adapted to control current through the at least one N-channel device, a second input current (ibiasp) adapted to control current through the at least one P-channel device, and an analog voltage input (delta) representing i) a predetermined ratio between respective on currents in the at least one P-channel device to ibiasp, and ii) the predetermined ratio between respective on currents in the at least one N-channel device to ibiasn.