Abstract: Compositions and methods for accurate and sensitive quantitation of T-tau and P-tau are disclosed.

Abstract: A packet of data and a packet-identification value are transmitted to a network device having an identifier. The stored packet-identification value and the identifier are recorded. The stored packet-identification value is then increased and the process repeats. To receive data, an expected identification value is stored in association with the identifier. A packet and a packet-identification value are received from the network device. The identifier and an indication of receipt are stored. If the received value does not match the expected value for the identifier, the received value is stored. If the values match, the stored packet-identification value and identifier are recorded. If the received value exceeds the expected value, the stored packet-identification value, the identifier and the received identifier are recorded. Subsequently, the stored expected value is increased. The process repeats. Network devices and systems are described.

Abstract: The present invention is based, in part, on our discovery of compositions and methods that can be used to treat a patient who has a compromised bone (due, for example, to a disease such as osteoporosis or an injury such as a bone fracture). The compositions can also be administered prophylactically. For example, they can be administered to help maintain bone health as a patient ages. More specifically, the compositions include polypeptides that constitute (or that include) a fragment of a calcitonin receptor (CR) and polypeptides that constitute (or include) biologically active variants of those fragments. Sequence-specific formulas are provided herein, and polypeptides conforming to those formulas, as well as nucleic acids encoding them, expression vectors, host cells, pharmaceutical formulations, and methods of their preparation and use are within the scope of the present invention.

Abstract: This document provides methods and materials involved in assessing intestinal permeability of a mammal. For example, methods and materials for administering 13C-mannitol to a mammal (e.g., a human) and determining urinary excretion of 13C-mannitol as a measure of intestinal permeability of a mammal are provided.

Abstract: A method of assisting a heart for the operation of a ventricular assist device comprising the steps of implanting a cannula to the heart and deploying a stent within a left ventricle, a right ventricle, a left atrium, or a right atrium of the heart. The stent may be transferable from a first compact configuration to a second open configuration to facilitate implantation. The stent may also have a flared distal end to assist with alignment, positioning, and prevent outgrowth.

Abstract: The present invention relates to a method of fabricating an organic structure directing agent-free CHA type zeolite membrane and a membrane fabricated thereby, and more particularly to a method of fabricating a continuous CHA type zeolite membrane, which exhibits CO2/N2 and CO2/CH4 separation performances comparable with those of conventional membranes, in a cost-effective manner without a calcination process by hydrothermal synthesis using an alkali metal hydroxide without using an organic structure directing agent, and to a membrane fabricated thereby.

Abstract: This invention provides novel indole, indazole, benzimidazole, benzotriazole, indoline, quinolone, isoquinoline, and carbazole selective androgen receptor degrader (SARD) compounds, pharmaceutical compositions and uses thereof in treating hyperproliferations of the prostate including pre-malignancies and benign prostatic hyperplasia, prostate cancer, advanced prostate cancer, castration resistant prostate cancer, other AR-expressing cancers, androgenic alopecia or other hyper androgenic dermal diseases, Kennedy's disease, amyotrophic lateral sclerosis (ALS), abdominal aortic aneurysm (AAA), and uterine fibroids, and to methods for reducing the levels (through degradation) and/or activity (through inhibition) of any androgen receptor including androgen receptor-full length (AR-FL) including pathogenic and/or resistance mutations, AR-splice variants (AR-SV), and pathogenic polyglutamine (polyQ) polymorphisms of AR in a subject.

Abstract: A scaffold comprising electrospun decellularized ECM of an organ, wherein the decellularized ECM has a similar protein composition to native ECM of the organ, Methods of generating same are also disclosed as well as uses of same.

Abstract: An image signal decoding method according to the present invention comprises the steps of: decoding information indicating whether a current block is encoded using a multi-mode intra prediction; when it is determined that the current block is encoded in the multi-mode intra prediction, dividing the current block into a plurality of partial blocks; and obtaining an intra prediction mode of each of the plurality of partial blocks.

Abstract: Systems and methods for fixing a stent in position in an anatomical lumen. Such systems and methods include an intra-luminal stent and a magnet, implanted, for example, in the subcutaneous layer of the subject. The stent and the magnet are magnetically coupled such that the magnetic forces fix the stent in position. Use of the invention permits fixation of an intra-luminal stent to avoid stent migration while minimizing tissue damage.

Abstract: Methods and compositions for modulating repeat non-ATG protein (RAN protein) translation are provided. In some aspects, the disclosure relates to methods for treating a subject having a disease associated with RAN protein translation by administering the subject a modulator of eIF3 or an eIF3 subunit, or an antibody that bind to a RAN protein.

Abstract: A resource recovery method includes: feeding raw water to a first-stage raw water tank; supplying high-temperature vapor to a first-stage heat exchanger; performing heat exchange between the supplied high-temperature vapor and the raw water in the first-stage raw water tank, changing a portion of the water into vapor and supplying the changed vapor to a subsequent-stage heat exchanger; repeatedly performing the performing step for each of the raw water tanks sequentially in the order from a second state to a n-th stage; being feed to a crystallizer from the n-th stage raw water tank; detecting a turbidity of the raw water fed to the crystallizer from the n-th-stage raw water tank; and extracting crystals of valuable resources contained in the raw water fed to the crystallizer from the n-th-stage raw water tank when the turbidity of the raw water becomes a predetermined value.

Abstract: A method for inhibiting metastasis of cancer cells is provided. Inhibitors of heparan sulfate (HS) or hyaluronic acid (HA) are applied to a tumor or a surgical location after removal of the bulk of the tumor. The inhibitors enzymatically cleave surface HS or HA; genetically modify cancer cells to decrease HS or HA production or interfere with the signaling pathway between HS or HA and a MMP or syndecan.

Abstract: Compositions and methods to prevent, inhibit or treat aveolar or periodontal bone loss, enhance bone regeneration, prevent, inhibit or treat peri-implantitis or periodontitis, e.g., periodontitis or peri-implantitis associated with bone loss, or to prevent, inhibit or treat osteoarthritis are provided.

Abstract: A non-transitory computer-readable medium encoded with a computer-readable program, which when executed by a processor, will cause a computer to execute a computational method, the computational method including collecting an image data, wherein the collecting the image data comprises collecting a first plurality of RGB images and a second plurality of hyperspectral images. The method further includes orthorectifying the image data to produce an RGB based orthophoto and a partially rectified hyperspectral orthophoto. The method further includes selecting tie features from each of the RGB based orthophoto and the partially rectified hyperspectral orthophoto. Lastly, the method includes registering the features of the partially rectified hyperspectral orthophoto into the tie features of the RGB based orthophoto.

Abstract: The present invention relates to an apparatus and method for encoding and decoding an image by skip encoding. The image-encoding method by skip encoding, which performs intra-prediction, comprises: performing a filtering operation on the signal which is reconstructed prior to an encoding object signal in an encoding object image; using the filtered reconstructed signal to generate a prediction signal for the encoding object signal; setting the generated prediction signal as a reconstruction signal for the encoding object signal; and not encoding the residual signal which can be generated on the basis of the difference between the encoding object signal and the prediction signal, thereby performing skip encoding on the encoding object signal.

Abstract: This invention provides a measure that makes it possible to prevent more effectively, in comparison with the prior art, the invasion of germs from the gap between a dental prosthesis and the gingiva when the dental prosthesis is used in an oral cavity as well as the infection and inflammation associated therewith. There is a dental prosthesis or a component thereof, characterized in that: the dental prosthesis or the component thereof has hydroxyapatite fine particles on a surface of the dental prosthesis or the component thereof; the hydroxyapatite fine particles are sintered bodies; and the hydroxyapatite fine particles have a mean particle size of 10 to 1,000 nm.

Abstract: An adjustable and self-locking fixation device for fixedly securing two structures wherein the device comprises two spans and a receiving aperture configured to receive the spans and form a closed loop around a first structure. The two spans are further configured to secure and lock onto each other so as to form a second closed loop around the two structures and secure the two structures in a tensioned state.

Abstract: A method for manufacturing a vehicle braking system including the steps of machining a hub so as to provide it with a nose and a tapped hole, mounting, on the nose of the hub, a ring having at least one relief extending in a direction perpendicular to a main axis of the ring, and rigidly attaching the ring to the hub such that the assembly, including the hub and the ring, forms a nut.

Abstract: Systems and methods for neutron detection using tensioned metastable fluid detectors, using a single atom spectroscopy approach.