Abstract: A ruggedized adjustable mounting system is described for adjustably coupling and selectively locking a component supported in a fixture of the mount in a desired orientation. In some embodiments, the mounting system includes one or more kinematic couplings that support a fixture on a base and one or more adjustable couplings that are configured to adjust a separation distance between two opposing portions of the fixture and the base to selectively pivot the fixture about one or more axes of rotation.

Abstract: The present description provides methods, assays and reagents useful for sequencing proteins. Sequencing proteins in a broad sense involves observing the plausible identity and order of amino acids, which is useful for sequencing single polypeptide molecules or multiple molecules of a single polypeptide. In one aspect, the methods are useful for sequencing multiple polypeptides. The methods and reagents described herein can be useful for high resolution interrogation of the proteome and enabling ultrasensitive diagnostics critical for early detection of diseases.

Abstract: Disclosed is a laser system including a first laser and a second laser. The first laser includes a laser cavity, and a gas phase molecular gain medium disposed in the laser cavity, the gain medium having an absorption band. The second laser is a solid state laser configured to be continuously tunable, with respect to an emission wavelength of the second laser, over the absorption band of the gain medium, and the second laser is tuned to pump rotational vibrational transitions in the gain medium to achieve a rotational population inversion.

Abstract: Systems and methods are disclosed herein for quantitatively identifying a patient's sedation level and predicting adverse events, based on one or more capnograms or outputs from a pharmacokinetic, pharmacodynamic, or ventilatory model. A sensor measures a carbon dioxide concentration of air exhaled by a patient into a breath receiver. A processor processes the sensor data to generate a capnogram including one or more respiratory cycles, computes the outputs of pharmacokinetic, pharmacodynamic, or ventilatory models, and extracts one or more of the resulting features from the capnogram and pharmacokinetic, pharmacodynamic, or ventilatory model outputs. A multi-parameter metric is computed based on the one or more extracted features and estimates the current or predicted sedation level of the patient.

Abstract: Systems and methods for a global positioning system using Global Navigation Satellite System (GNSS) signals and Stokes Parameters in accordance with embodiments of the invention are illustrated. One embodiment includes a GNSS. The GNSS includes at least four satellites and a receiver. Each satellite includes at least one pair of antennas, and a transmitter configured to transmit GNSS positioning signals to a receiver. The receiver includes a memory containing a positioning application, and a processor comprising a set of one or more processors, the positioning application configures the processors to determine a position of the receiver by performing the steps of collecting horizontal and vertical linear components of transmitted GNSS positioning signals, computing Stokes parameters of collected GNSS signals, obtaining tuning parameters based on computed Stokes parameters, synthesizing new polarization signal using tuning parameters, and processing new polarization signal to obtain a position of the location.

Abstract: Reaction schemes involving acids and bases; reactors comprising spatially varying chemical composition gradients (e.g., spatially varying pH gradients), and associated systems and methods, are generally described.

Abstract: Chemical reaction devices involving acid and/or base, and related systems and methods, are generally described.

Abstract: An air-coupled ultrasonic plane stress detection method for a composite material based on dual-modal sound-time ratios of a Lamb wave includes: S1: assembling a detection device; S2: based on the detection device and the dual-modal sound-time ratios of the Lamb wave in S1, using unidirectionally loaded stress to obtain different stress coefficient relations; S3: based on the stress coefficient relations in S2, solving stress coefficients; S4: based on the stress coefficients in S3, acquiring three sound-time ratios; S5: based on the sound-time ratios in S4, describing a stress state of a detection point; and S6: repeating S4 and S5 till completing detection and scanning. The method improves the accuracy of stress coefficient calibration and air-coupled ultrasonic stress representation of a composite material panel greatly.

Abstract: Systems and methods for electrochemical hydrogen looping cells are described. Generating a pH swing can expedite carbon dioxide capture from oceanwater. Many embodiments implement electrochemical hydrogen looping cells that simultaneously produce acid via anodic hydrogen oxidation and base via cathodic hydrogen evolution to generate a pH change.

Abstract: Systems and methods involving nanomaterial-based electrodes, such as supercapacitor and battery electrodes that can be flexible, are described.

Abstract: Electrochemical removal of chemical products in seawater, or other aqueous environments, resulting from increased atmospheric carbon dioxide levels is described.

Abstract: The systems and methods for monitoring and/or regulating thermal parameters in convective flow batteries is generally described.

Abstract: Quantum sensors provide excellent performance combining high sensitivity with spatial resolution. Unfortunately, they can only detect signal fields at frequencies in a few accessible ranges, typically low frequencies up to the experimentally achievable control field amplitudes and a narrow window around their resonance frequencies. Fortunately, arbitrary-frequency signals can be detected by using the sensor qubit as a quantum frequency mixer, enabling a variety of sensing applications. The technique leverages nonlinear effects in periodically driven (Floquet) quantum systems to achieve quantum frequency mixing of the signal and an applied AC bias field. The frequency-mixed field can be detected using Rabi and CPMG sensing techniques with the bias field. Frequency mixing can distinguish vectorial components of an oscillating signal field, thus enabling arbitrary-frequency vector magnetometry.

Abstract: A sensor can include one or more of a semiconducting material, an oxidation catalyst, and an oxidation enhancer, the sensor being configured to detect an analyte, such as methane, a thiol, or both.

Abstract: Disclosed are particles for delivering cytokinese, such as IL-12, for the treatment of cancer. The particles comprise cytokines non-covalently bound to liposomes, where the liposomes are coated with polyelectrolytes.

Abstract: The present invention relates to methods for secure computation and/or communication. Entangled photons (118) are generated such that each participating party receives a series of optical pulses. Each party has private information (110, 112) which are never transmitted through public or private communication channels. Instead, each party converts their respective private information (110, 112) into measurement bases via an encryption process (114, 116) which are then applied to the entangled photons (118). After the measurement process, e.g., quantum frequency conversion (122, 124), reference indices are announced (124, 126) so that computation can be performed (128) without revealing the private information directly or indirectly.

Abstract: A system for non-invasive hematological measurements includes a platform to receive a body portion of a user and an imaging device to acquire a set of images of a capillary bed in the body portion. For each image, a controller detects one or more capillaries in the body portion of the finger to identify a first set of capillaries by estimating one or more attributes of each capillary (e.g., structural attributes, flow attributes, imaging attributes, or combinations thereof), wherein at least one attribute of each capillary meets a predetermined criterion. The controller also identifies a second set of capillaries from the first set of capillaries such that each capillary of the second set of capillaries is visible in a predetermined number of images of the set of images.

Abstract: Disclosed is a hollow sulfide microsphere with enriched sulfur vacancies, which is prepared by a method comprising the steps of: dissolving cobalt nitrate and nickel nitrate in a mixed solution of N, N-dimethylformamide and acetone with an equal volume; then adding a chelating agent thereto, subjecting a resulting mixture to a solvothermal reaction to obtain a coordination polymer microsphere; dissolving the coordination polymer microsphere and a sulfurization agent in an organic solvent, and reacting to obtain a hollow sulfide microsphere; and subjecting the hollow sulfide microsphere to reduction treatment with sodium borohydride, centrifuging, washing and drying to obtain the hollow sulfide microsphere with enriched sulfur vacancies having a particle size of 1-2.5 ?m, a shell thickness of 15-30 nm and a specific capacity of the material of 763.4 C g?1 (current density is 1 A g?1).

Abstract: Described herein are compositions and methods of using single-cell RNA-sequencing to identify treatment resistance in patients with ovarian cancer. Also, described herein are compositions and methods for treatment targeting resistance in patients with ovarian cancer.

Abstract: Compositions and methods are described for inducing an immune response against an immunogen in humans. The induced immune response is obtained by administering a heterologous prime-boost combination of an in vitro transcribed (IVT) self-replicating RNA (repRNA) and an adenovirus vector. The compositions and methods can be used to provide a protective immunity against a disease, such as a viral infection or a cancer, in humans.