Abstract: Provided herein is an improved method for performing CRISPR/Cas based screening that is not dependent on viral cloning methods.

Abstract: The present invention relates to a battery case and a battery cooling system. The battery case includes an outer case; an inner case spaced apart from the outer case; and an intermediate member in a separation space between the outer case and the inner case, wherein the intermediate member includes: a plurality of peak portions which protrudes upward in a shape corresponding to a shape of a plurality of lower pins; a plurality of valley portions which protrudes downward in a shape corresponding to a shape of a plurality of upper pins; and a connection portion disposed between the peak portion and the valley portion.

Abstract: Presented herein, in certain embodiments, are compositions comprising antibody binding agents that specifically bind to A. baumannii and inhibit and/or block A. baumannii infection, and uses thereof.

Abstract: The present disclosure relates to a saccular cavopulmonary assist device, including a shell, an inflow tube (6) and an outflow tube (4), wherein a blood storage cavity (A) and a power cavity (B) are arranged in the shell, and the power cavity (B) is used for providing contraction and relaxation power for the blood storage cavity (A); the inflow tube (6) is arranged at a position corresponding to the power cavity (B) on the shell, an outer end is used for communicating with the vena cava, and an inner end communicates with the blood storage cavity (A) after passing through the power cavity (B); the outflow tube (4) is arranged at a position corresponding to the blood storage cavity (A) on the shell, an outer end is used for communicating with the pulmonary artery, and an inner end communicates with the blood storage cavity (A).

Abstract: The present invention relates to a rotating self-drilling device for extraterrestrial objects.

Abstract: The present invention provides novel compounds of Formulae (I?) and (II), and pharmaceutically acceptable salts, solvates, hydrates, polymorphs, co-crystals, tautomers, stereoisomers, isotopically labeled derivatives, prodrugs, and compositions thereof. Also provided are methods and kits involving the inventive compounds or compositions for treating and/or preventing proliferative diseases (e.g., cancers (e.g., leukemia, acute lymphoblastic leukemia, lymphoma, Burkitt's lymphoma, melanoma, multiple myeloma, breast cancer, Ewing's sarcoma, osteosarcoma, brain cancer, ovarian cancer, neuroblastoma, lung cancer, colorectal cancer), benign neoplasms, diseases associated with angiogenesis, inflammatory diseases, autoinflammatory diseases, and autoimmune diseases) in a subject. Treatment of a subject with a proliferative disease using a compound or composition of the invention may inhibit the aberrant activity of a kinase, such as a cyclin-dependent kinase (CDK) (e.g.

Abstract: Provided herein are CRISPR/Cas methods and compositions for targeting RNA molecules, which can be used to detect, edit, or modify a target RNA.

Abstract: Methods and apparatuses for using a neural network based model to predict an output port for a destination Internet Protocol (IP) address in a network are described. Some embodiments can construct an untrained model comprising a graph neural network (GNN), a first artificial feed-forward neural network (ANN), and a second ANN. Next, the embodiments can train the untrained model to obtain a trained model by: training the first ANN using at least IP addresses of destination nodes in the network, training the GNN using at least an adjacency matrix of the network and initial node features computed using the IP addresses of destination nodes in the network, and training the second ANN by combining the output of the first ANN and an output of the GNN using an attention mechanism. The embodiments can then use the trained model to predict the output port for the destination IP address.

Abstract: A method of predicting a life of a membrane electrode assembly (MEA) of a fuel cell for electric power generation includes: deriving an operating condition for accelerated degradation, which is applicable to the fuel cell; operating the fuel cell for a specific time under the derived operating condition for accelerated degradation and under a normal operating condition, and identifying the degree of degradation of the fuel cell under each of the operating conditions; calculating an acceleration multiple based on the degree of degradation identified under the operating condition for accelerated degradation and under the normal operating condition; and predicting the life of the membrane electrode assembly based on the acceleration multiple.

Abstract: An aromatization catalyst and preparation process and use thereof is set forth. The catalyst comprises an inorganic oxide and a modified Ga-ZSM-5 zeolite, which comprises a modified ZSM-5 zeolite with a hierarchical macro-meso-microporosity and gallium deposited in channels of and/or on surfaces of the modified ZSM-5 zeolite. The hierarchical porosity of the modified ZSM-5 zeolite in the catalyst can reduce diffusion resistance of products during the aromatization reaction, thereby retarding carbon depositing rate and substantially improving catalytic activity, aromatic hydrocarbon selectivity, stability and lifetime of the catalyst. When being used in aromatization of propane, the catalyst exhibits a high stability, a lifetime of more than 320 hours, and a selectivity to aromatic hydrocarbons of up to 73.3 wt. %.

Abstract: A method for producing methyldichlorophosphane, the method including: allowing methane and phosphorus trichloride to react in the presence of an additive using a metal compound, or a metal compound carried on a carrier, or both thereof.

Abstract: The present invention provides a method for monitoring electrical power in high-speed rail traction power supply networks/systems, comprising: collecting voltage and current analog signals from a traction power supply system, and converting the voltage and current analog signals into voltage and current digital signals; obtaining, by a processing unit, digital signals and transfer commands; compressing, by the processing unit, the digital signals according to the transfer commands to digital signal frames; and constructing a data link between the processing unit and a storage unit and transmitting the compressed digital signal frame to the storage unit. The processing unit may use run-length coding algorithm to compress the digital signal to be stored to obtain several compressed digital signal frames. Under different conditions of data link, transmission of compressed digital signal frames is adjustable to improve the reliability of digital signal transmission.

Abstract: The present invention relates to a method and apparatus for transceiving data. A method in which a transmitting terminal transmits data to a receiving terminal in a MIMO system according to one embodiment of the present invention comprises the following steps: generating a data field containing the data; generating a signal field containing information on the data field; generating a data frame containing the data field and the signal field; and transmitting the data frame to the receiving terminal. According to the present invention, an end of the frame being transmitted is accurately notified to the receiving terminal in a communication system in which the frame is transmitted using MIMO, thereby decoding the frame in a more efficient manner at the receiving terminal.

Abstract: The present invention relates to a patterned fiber substrate comprising: a fiber substrate; and a pattern consisting of a functional material and formed on the fiber substrate, wherein at least a part of the functional material that constitutes the pattern is present in inside of the fiber substrate, the fiber substrate has a contact angle of 100 to 170° with pure water on its surface, and the pattern has a narrowest line width of 1 to 3000 ?m.

Abstract: Embodiments relate to a system and method for calibrating a ratio of body size of a subject including setting a body coordinate system of each body segment of the subject, calculating a first rotation matrix from a world coordinate system set based on the ground to a sensor coordinate system of each motion sensor when the subject takes a first basic pose, calculating a second rotation matrix from the world coordinate system to the sensor coordinate system of each motion sensor when the subject takes a second basic pose, calculating a third rotation matrix from the world coordinate system to the body coordinate system of a trunk for a first motion sensor attached to the trunk of the subject, and calculating a ratio of body size of the subject based on the third rotation matrix.

Abstract: Methods for synthesizing crystalline Ni-rich cathode materials are disclosed. The Ni-rich cathode material may have a formula LiNixMnyMzCo1?x?y?zO2, where M represents one or more dopant metals, x?0.6, 0.01?y<0.2, 0?z?0.05, and x+y+z?1.0. The methods are cost-effective, and include methods for solid-state, molten-salt, and flash-sintering syntheses.

Abstract: A solid electrolyte having high electrical conductivity even in a low-temperature region is provided. A solid electrolyte containing a hexagonal perovskite-related compound, in which the compound is a compound represented by the following general formula (1), and an electrolyte layer and a battery using the solid electrolyte are disclosed. Ba7-?Nb(4?x-y)Mo(1+x)MyO(20+z) (1), in the formula (1), M is a cation of at least one element; a represents a Ba deficiency amount and represents a value of 0 or more and 0.5 or less, x represents a value of ?1.1 or more and 1.1 or less, y represents a value of 0 or more and 1.1 or less, and z represents an oxygen non-stoichiometry and represents a value of ?2.0 or more and 2.0 or less, provided that in the formula (1), |x|+y?0.01 is satisfied.

Abstract: The present disclosure provides compounds of Formula (I), and salts, solvates, hydrates, polymorphs, co-crystals, tautomers, stereoisomers, isotopically labeled derivatives, and prodrugs thereof. The provided compounds may be useful for inhibiting kinases, e.g., glycogen synthase kinase 3 (GSK3). The provided compounds may be able to selectively inhibit GSK3a, as compared to GSK3P and/or other kinases. The present disclosure further provides pharmaceutical compositions, kits, and methods of use, each of which involve the compounds. The compounds, pharmaceutical compositions, and kits may be useful for treating diseases associated with aberrant activity of GSK3a (e.g., Fragile X syndrome, attention deficit hyperactivity disorder (ADHD), childhood seizure, intellectual disability, diabetes, acute myeloid leukemia (AML), autism, and psychiatric disorder).

Abstract: An image recognition method, including: obtaining an image to be recognized by an image sensor; inputting the image to be recognized to a single convolutional neural network; obtaining a first feature map of a first detection task and a second feature map of a second detection task according to an output result of the single convolutional neural network, wherein the first feature map and the second feature map have a shared feature; using an end-layer network module to generate a first recognition result corresponding to the first detection task from the image to be recognized according to the first feature map, and to generate a second recognition result corresponding to the second detection task from the image to be recognized according to the second feature map; and outputting the first recognition result corresponding to the first detection task and the second recognition result corresponding to the second detection task.

Abstract: The present invention relates to an exceptionally broad and potent neutralizing antibody which may comprise cross-clade neutralizing coverage of 83% at a median IC50 of 0.003 ?g/ml, compositions containing the same and uses thereof.