Abstract: The present invention is based, in part, on the identification of novel methods for defining predictive biomarkers of response to anti-cancer drugs.

Abstract: An inkjet-printing-base process for depositing functional materials, for example PZT, on a substrate, in various instances platinized silicon. Substrate templating (via SAMs) and material deposition are both performed by an inkjet printing process. Additionally, a composition to be used as a SAM precursor ink which is a thiol in a solvent mixture, wherein the composition can be 1 dodecanethiol in a solvent mixture of 2-methoxyethanol and glycerol.

Abstract: The invention relates to a process for treating lignocellulosic biomass by means of an acidic liquor in order to produce “second-generation” (2G) sugary liquors. These sugary liquors may be used to produce other products via a biochemical pathway (e.g. alcohols such as ethanol, butanol or other molecules, for example solvents such as acetone, etc.). This process comprises analysis of the liquid streams withdrawn during the process and adjustment of the composition of the impregnation liquor so as to keep the acidic power of said streams constant.

Abstract: The present application relates to a magnesium oxide based dielectric ceramics with ultrahigh dielectric breakdown strength and a preparation method thereof. The composition of the magnesium oxide based dielectric ceramic material comprises: (1?x)MgO—xAl2O3, wherein 0<x?0.12 and x is a mole percentage. The material has a specific composite structure with magnesium aluminate spinel acting as a second phase surrounding a principal crystalline phase, MgO.

Abstract: Provided herein are CRISPR/Cas methods and compositions for targeting RNA molecules, which can be used to detect, edit, or modify a target RNA.

Abstract: An Electro-Static-Discharge (ESD) protection circuit has a Silicon-Controlled Rectifier (SCR) with a discharge current path in a first direction. A triggering transistor has a trigger current flowing in a second direction that is perpendicular to the first direction. Triggering transistors can be Fin Field-Effect Transistor (FinFET) transistors with current flowing along the long direction of the fins. The trigger current flows into a connecting N+ drain and into an N-Well under a center portion of the connecting N+ drain to inject carriers into the N-base of a PNPN SCR. The injected current flows through the base to generate a voltage gradient that turns on the PN junction in a P+ emitter that is parallel to but spaced apart from the FinFET transistors, causing a discharge current to flow perpendicular to the fins. The perpendicular discharge current flows through the substrate which can handle a larger current than the small fins.

Abstract: Provided herein are CRISPR/Cas methods and compositions for targeting RNA molecules, which can be used to detect, edit, or modify a target RNA.

Abstract: A method is disclosed for use in a planning agent, the method including: identifying a first agent in a vicinity of the planning agent; identifying a location of the first agent and a velocity of the first agent; calculating a set of occupancy costs for the first agent, each occupancy cost in the set of occupancy costs being associated with a different respective location in the vicinity of the planning agent, each occupancy cost in the set of occupancy costs being calculated at least in part based on a cost function that depends on the location of the first agent and the velocity of the first agent; and changing at least one of speed or direction of travel of the planning agent based on the set of occupancy costs.

Abstract: A highly-dielectric, elastic structure includes an elastic body that is highly-dielectric and includes a polymer matrix that including 1000 pbw of a polydimethylsiloxane (PDMS) base and 100 pbw of a PDMS curing agent, and has a tensile strength of 0.1 to 10 MPa; and 22.4 pbw of carbon black that is surface-treated with octadecyltrimethoxysilane (ODTMS) in an amount of at least 0.707 mmol per 22.4 pbw of the carbon black, and that is dispersed in the polymer matrix and cured; and an adhesive electrode that is stretchable, that is disposed on the elastic body, and that includes a polymer adhesive including a 500 pbw of a thermosetting silicone-based polymer adhesive including a curable polymer and a curing agent; and a conductive filler comprising 500 pbw of silver particles and 4000 pbw of a carbonaceous material that is a multi-walled carbon nanotube that are dispersed in the polymer adhesive and cured.

Abstract: The current subject matter includes methods, systems, articles, and techniques to deliver material to anucleate cells, such as red blood cells. Using a rapid deformation based microfluidic system, loading of red blood cells with macromolecules of different sizes has been shown. Although delivery to some mammalian cells, such as cancer cell lines and fibroblasts had been previously demonstrated using this technique, those designs were incompatible with RBCs that have dramatically different physical properties. Through the use of smaller constriction sizes, high speeds and different buffers successful delivery to red blood cells can be achieved. By enabling robust delivery to red blood cells in a simple, scalable manner, the current subject matter can be implemented in a diversity of applications that deliver material to study red blood cell diseases and/or use red blood cells as a therapeutic platform. Related apparatus, systems, techniques, and articles are also described.

Abstract: A synchronization information transmission method includes: receiving synchronization information sent by a preceding node; on the basis of synchronization accuracy information of a current node, updating intermediate node information in the synchronization information; and sending the updated synchronization information to a subsequent node.

Abstract: The present disclosure generally relates to apparatuses, systems, and methods for separating a target species (e.g., CO2) from a gas mixture (e.g., gas stream) via an electrochemical process.

Abstract: A direct liquid fuel cell power generation device comprises a direct liquid fuel cell system and a low-temperature auxiliary starting component. A heat exchanger is arranged at a stack cathode inlet. The heat of a fuel solution at a stack anode outlet is used to heat the air. The heat generated by an electronic load for starting is used to heat a condenser. The heat of a methanol solution at a liquid outlet of a gas-liquid separator is used to preheat high-concentration fuel flowing into a refueling pump. Starting and operation in a low-temperature environment can be realized through auxiliary heating of external power supplies such as the low-temperature auxiliary starting component or an in-vehicle cigarette lighter. Organic micromolecule substances such as methanol and ethanol are used as fuel and are subjected to catalytic combustion in a catalytic combustor.

Abstract: A three-degree-of-freedom bearingless switched reluctance motor excited by a constant current source includes a rotor and a stator. The rotor consisting of a rotating shaft and a rotor core, where a plurality of rotor teeth is uniformly distributed on an outer circumference of the rotor core. The stator includes a stator core, a magnetic isolation ring, an axial suspension winding, and a magnetic conduction ring that are sequentially connected, and axial control cores and annular constant current source windings which are symmetrically arranged on both sides of the stator core. Outer edges of the axial control cores are connected to the magnetic conduction ring, and inner edges extend to the rotor core. The stator core and the magnetic isolation ring both consist of an axial part and a radial part of which an outer end is connected to an inner wall of the axial part.

Abstract: A laser panel, a laser array device, and a laser display. The laser panel and the laser array device separately comprise multiple groups of independent laser light source modules; each group of laser light source modules comprises plural light sources; the plural light sources are all produced by inkjet printing; the laser display and a voltage-driven laser display separately comprise the laser panel. Producing a laser panel by inkjet printing provides a novel technical solution for cheap and industrial manufacturing of laser panels. It is difficult to generate laser coherent superposition between the light emitted by the laser light source module, and therefore, speckles caused by laser coherence in conventional laser display technologies are greatly eliminated. The present invention achieves a voltage-driven laser display, and facilitates achieving a better display effect while reducing the volume of the display.

Abstract: A hand-wearable device includes an elastic sheet including a first elastic layer and a second elastic layer facing each other; a sensor unit formed by printing a predetermined conductive liquid metal between the first elastic layer and the second elastic layer; a wire unit extending from the sensor unit and electrically connected to the sensor unit; an electrode substrate formed on one side of the wire unit and spaced apart from the wire unit by a predetermined distance; and a connection electrode formed by printing a predetermined conductive liquid metal between the wire unit and the electrode substrate.

Abstract: A filament platform insert for insertion into a bowl includes a plurality protruding stages and a plurality of recesses that are each formed in arcuate shapes to form a plurality of arcuate filament channels. An access channel extending along the platform insert, between a top and bottom, and between a rear and front, provides access for insertion of a finger or tool for manipulating an endovascular filament stored in the filament channel. The platform insert is dimensioned such that alignment of multiple such platforms will form filament raceways within a bowl for the coiled reception and storage of multiple endovascular filaments, with each filament reliably isolated from one another. In an alternative configuration, an endovascular filament bowl may be made to have the filament platform as a monolithic component thereof.

Abstract: A minimally invasive surgical device includes a main body, a buffer assembly and a cutter bit. The main body includes an inner tube and an outer tube, wherein the inner tube is disposed in the outer tube. An end of the buffer assembly is connected to the inner tube. The cutter bit is connected to another end of the buffer assembly, wherein the cutter bit has a cutting portion. When the cutting portion is in contact with an object, the buffer assembly is adapted to enable the cutter bit to move relatively to the inner tube to decrease a cutting force between the cutting portion and the object, and is adapted to enable the cutting portion to be tilted with a surface of the object.

Abstract: In order to solve a problem that the level of precision in inferring a crosslingual topic of documents or words in a non-parallel corpus associated in the document level is not high, a topic inferring apparatus includes: a word distribution information storage unit in which word distribution information is stored in association with each of two or more languages; a document topic distribution generating unit that acquires document topic distribution information of a multilingual document set; a segment topic distribution generating unit that acquires segment topic distribution information of each segment, using the document topic distribution information; and a word topic determining unit that determines, for each word contained in two or more documents contained in the multilingual document set, a topic of each word using the segment topic distribution information. Accordingly, it is possible to improve the level of precision in inferring a topic.

Abstract: A LiDAR odometry method based on the directed geometric point and sparse frame includes: obtaining original three-dimensional point cloud data of a surrounding environment in the coordinate system of the current frame of the LiDAR sensor; constructing and converting the first directed geometric point set and first environmental directed geometric point set into the second directed geometric point set and second environmental directed geometric point set in the world coordinate system, respectively; calculating candidate associated points in the second environmental directed geometric point set in association with each point in the second directed geometric point set, and determining the best associated point of each point in the second directed geometric point set; constructing and solving a pose optimization function to obtain an optimized pose from the coordinate system of the current frame of the LiDAR sensor to the world coordinate system; and updating directed geometric point sets of sparse frames.