Patents Assigned to INSTITUTE
  • Patent number: 11238998
    Abstract: An in-vessel cooling and power generation system according to the present disclosure may include a small scale reactor vessel, a heat exchange section provided inside the reactor vessel, and formed to supply supercritical fluid to receive heat from a reactor coolant system in the reactor vessel, an electric power production section comprising a supercritical turbine formed to produce electric energy using the energy of the supercritical fluid whose temperature has increased while receiving heat from the reactor coolant system, a cooling section configured to exchange heat with the supercritical fluid discharged after driving the supercritical turbine to shrink a volume of the supercritical fluid, wherein the supercritical fluid that has received heat from the reactor coolant system in the heat exchange section is formed to circulate through the electric power production section, and the cooling section.
    Type: Grant
    Filed: May 23, 2018
    Date of Patent: February 1, 2022
    Assignees: KOREA ATOMIC ENERGY RESEARCH INSTITUTE, KING ABDULLAH CITY FOR ATOMIC AND RENEWABLE ENERGY
    Inventors: Youngin Kim, Seungyeob Ryu, Joohyung Moon, Soojai Shin, Seok Kim, Hyunjun Cho, Juhyeon Yoon, Kilsung Kwon
  • Patent number: 11236041
    Abstract: The present invention discloses a type-G crystal form of fenolamine, a preparation method thereof, and a composition and use thereof. In particular, disclosed is a type-G crystal form of the fenolamine compound (chemical name: trans-2-(2,5-dimethoxyphenyl)-3-(4-hydroxy-3-methoxyphenyl)-N-(4-hydroxyphenylethyl)acrylamide, a preparation method thereof, and a composition and use thereof. Specifically, the present invention discloses the presence of a solid of a type-G fenolamine crystal form in solid state; a method for preparing the solid of type-G crystal form; and use of the solid of the type-G fenolamine crystal form as a pharmaceutical active ingredient in the manufacture of a medicament for prevention and treatment of Parkinson's disease (PD), improvement of learning and memory disorder, and treatment of memory loss and Alzheimer's disease (AD).
    Type: Grant
    Filed: September 7, 2018
    Date of Patent: February 1, 2022
    Assignees: INSTITUTE OF MATARIA MEDICA, CHINESE ACADEMY OF MEDICAL SCIENCES, SHIJIAZHUANG YILING PHARMACEUTICAL CO., LTD.
    Inventors: Yang Lv, Shiying Yang, Gengtao Liu, Dan Zhang, Xiuqi Bao, Ping Xie
  • Patent number: 11237143
    Abstract: Reagents and methods are disclosed for detection of oxidizers and inorganic salts and other analytes of interest. The reagents can interact with their target analytes, especially oxidizer compositions or oxidizer-based explosives, to selectively enhance their ionization yield, interacting by chemical reaction or by forming an associative adduct which facilitates their detection. For example, the reagents can adduct with the counter-ion of the intended analyte for improved direct detection and/or react chemically via acid-base reactions to produce a new product for detection. In another aspect of the invention, reactive reagents and methods are also disclosed that facilitate indirect detection of the analyte at lower temperatures based on reduction-oxidation (redox) chemistry. These reagents are particularly useful in detecting oxidizer analytes.
    Type: Grant
    Filed: February 17, 2017
    Date of Patent: February 1, 2022
    Assignee: Massachusetts Institute Of Technology
    Inventors: Kerin E. Gregory, Roderick R. Kunz, Michael Sworin
  • Patent number: 11235283
    Abstract: An ionic liquid and a forward osmosis process employing the same are provided. The ionic liquid has a structure represented by Formula (I) ABn??Formula (I), wherein A is n is 1 or 2; m is 0, or an integer from 1 to 7; R1 and R2 are independently methyl or ethyl; k is an integer from 3 to 8; B is i is independently 1, 2, or 3; and j is 5, 6, or 7. The forward osmosis process employing the ionic liquid is used to desalinate a brine via a forward osmosis (FO) model.
    Type: Grant
    Filed: December 30, 2019
    Date of Patent: February 1, 2022
    Assignee: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE
    Inventors: Po-I Liu, Hsin Shao, Min-Chao Chang, Yi-Chun Chen, Chiung-Hui Huang, Chia-Hua Ho, David Chiuni Wang, Ren-Yang Horng
  • Patent number: 11236134
    Abstract: The present invention provides HIV-1 vaccine immunogens. Some of the immunogens contain a soluble gp140-derived protein that harbors a modified N-terminus of the HR1 region in gp41. Some of the immunogens contain an HIV-1 Env-derived trimer protein that is presented on a nanoparticle platform. The invention also provides methods of using the HIV-1 vaccine immunogens for eliciting an immune response or treating HIV infections.
    Type: Grant
    Filed: February 3, 2020
    Date of Patent: February 1, 2022
    Assignee: The Scripps Research Institute
    Inventors: Leopold Kong, Ian A. Wilson, Natalia De Val, Andrew B. Ward, Dennis Burton, Linling He, Jiang Zhu
  • Patent number: 11239081
    Abstract: A method for preparing an ohmic contact electrode of a GaN-based device. Said method comprises the following steps: growing a first dielectric layer (203) on an upper surface of a device (S1); implanting silicon ions and/or indium ions in a region of the first dielectric layer (203) corresponding to an ohmic contact electrode region, and in the ohmic contact electrode region of the device (S2); growing a second dielectric layer (206) on an upper surface of the first dielectric layer (203) (S3); activating the silicon ions and/or the indium ions by means of a high temperature annealing process, so as to form an N-type heavy doping (S4); respectively removing portions, corresponding to the ohmic contact electrode region, of the first dielectric layer (203) and the second dielectric layer (206) (S5); growing a metal layer (208) on the upper surface of the ohmic contact electrode region of the device, so as to form an ohmic contact electrode (S6).
    Type: Grant
    Filed: February 27, 2019
    Date of Patent: February 1, 2022
    Assignee: THE 13TH RESEARCH INSTITUTE OF CHINA ELECTRONICS
    Inventors: Yongliang Tan, Xingzhong Fu, Zexian Hu, Xiangwu Liu, Lijiang Zhang, Yuxing Cui, Xingchang Fu
  • Patent number: 11236279
    Abstract: Internal combustion engines tolerant to tar-containing producer gas are disclosed. Two concepts are described. The engines are tolerant to producer gas from a biomass gasifier with minimal pretreatment. When biomass is gasified to be burned for power generation or to be used to synthesize chemicals such as biofuels, a large fraction of the installation cost is spent on equipment to clean up the heavy organic components (also referred to as ‘tars’) from the gas stream, hereafter referred to as ‘producer gas’. The invention described herein may be used to enable power generation from gasified biomass with minimal treatment. It may also be used to treat biomass at a very low cost for other uses such as synthesizing chemicals. The producer gas is not necessarily limited to biomass derived. Producer gas derived from coal or other sources has similar issues and the invention described herein would be equally applicable.
    Type: Grant
    Filed: December 20, 2017
    Date of Patent: February 1, 2022
    Assignee: Massachusetts Institute of Technology
    Inventors: Emmanouil Kasseris, Leslie Bromberg
  • Patent number: 11239222
    Abstract: Provided is a cooled optical transmission module device including a silicon wafer having a plurality of platform mounting grooves, each of which serves as a space for mounting in which an optical transmission platform therein, a thermoelectric cooler bonded to the platform mounting groove to transfer heat to outside, the optical transmission platform provided on the thermoelectric cooler and configured to output an optical signal by generating and reflecting the optical signal, a dielectric sub-mount bonded to the platform mounting groove of the silicon wafer and electrically connected to the mounted optical transmission platform, and a cover configured to cover the platform mounting groove of the silicon wafer and seal the platform mounting groove while providing an electric path.
    Type: Grant
    Filed: October 27, 2020
    Date of Patent: February 1, 2022
    Assignee: ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTE
    Inventors: Eun Kyu Kang, Jong Jin Lee, Sang Jin Kwon, Won Bae Kwon, Dae Seon Kim, Soo Yong Jung
  • Patent number: 11240081
    Abstract: A UE in a wireless communication system is disclosed. The UE includes a communication module and a processor for controlling the communication module. The processor determines a first cyclic shift (CS) value based on hybrid automatic repeat request acknowledgment (HARQ-ACK) information representing a response to a downlink channel having been received from a base station, determines a CS offset based on request information representing a request to be transmitted from the UE to the base station, determines a second CS value representing a degree of cyclic-shifting a base sequence to be used in a physical uplink control channel (PUCCH) based on the first CS value and the CS offset, and transmits the PUCCH for simultaneous transmission of the request information and the HARQ-ACK information using a sequence generated by cyclic-shifting the base sequence based on the second CS value.
    Type: Grant
    Filed: February 7, 2020
    Date of Patent: February 1, 2022
    Assignee: WILUS INSTITUTE OF STANDARDS AND TECHNOLOGY INC.
    Inventors: Minseok Noh, Jinsam Kwak, Kyungjun Choi, Hyukmin Son
  • Patent number: 11239569
    Abstract: Described is a stacked patch antenna array scan-capable to 55 degrees and operable over an octave or greater frequency bandwidth.
    Type: Grant
    Filed: February 28, 2020
    Date of Patent: February 1, 2022
    Assignee: Massachusetts Institute of Technology
    Inventor: Pierre A. Dufilie
  • Patent number: 11240166
    Abstract: The present invention relates to a wireless communication terminal and a wireless communication method for efficiently scheduling uplink multi-user transmission. To this end, provided are a base wireless communication terminal, including: a transceiver configured to transmit and receive a wireless signal; and a processor configured to control an operation of the transceiver, wherein the processor selects an access category for transmitting a trigger frame which solicits an uplink multi-user transmission, performs a backoff procedure for transmitting the trigger frame based on the selected access category, and transmits the trigger frame when a backoff counter of the backoff procedure expires and a wireless communication method using the same.
    Type: Grant
    Filed: June 22, 2020
    Date of Patent: February 1, 2022
    Assignees: WILUS INSTITUTE OF STANDARDS AND TECHNOLOGY INC., SK TELECOM CO., LTD.
    Inventors: Jinsoo Ahn, Yongho Kim, Jinsam Kwak, Juhyung Son
  • Patent number: 11234651
    Abstract: Apparatus, system and method for medical analysis of a seated individual, includes determining the aortic valve opening; the PTT; and calculating the PWV. Determining the aortic valve opening includes collecting BCG data while sitting on a seat and determining the timing of the aortic valve opening, taking into account posture. Measuring the aortic pulse wave transit time includes collecting BCG data while sitting on a seat capable of measuring changes in apparent weight; determining the timing of the aortic valve opening; detecting the arrival of the pulse wave at the end point; and measuring the relative timings of the two events. Calculating the PWV includes determining a length of the arterial segment through which a pulse wave is to be measured between a start point and an end point; and dividing the determined length of the arterial segment by the PTT.
    Type: Grant
    Filed: April 8, 2019
    Date of Patent: February 1, 2022
    Assignee: Rochester Institute of Technology
    Inventors: David A. Borkholder, Nicholas J. Conn, Masoumeh Haghpanahi
  • Patent number: 11239141
    Abstract: A lead frame package including first conductive layer, first electronic component, lead frames, second conductive layer and package body. First conductive layer has conductive carriers. First electronic component has first pins. Lead frames and first pins are respectively electrically connected to conductive carriers. Second conductive layer has conductive joints respectively electrically connected to lead frames so as to be electrically connected to at least a part of conductive carriers via lead frames. Package body encapsulates first conductive layer, first electronic component, and lead frames. First conductive layer and second conductive layer are located on two opposite sides of first electronic component, respectively.
    Type: Grant
    Filed: September 24, 2020
    Date of Patent: February 1, 2022
    Assignee: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE
    Inventors: Ren-Shin Cheng, Shih-Hsien Wu, Yu-Wei Huang, Chih Ming Shen, Yi-Chieh Tsai
  • Patent number: 11239323
    Abstract: An object is to provide a technology for enabling prevention of deterioration of characteristics of an oxide semiconductor device. The oxide semiconductor device includes an n-type gallium oxide epitaxial layer, a p-type oxide semiconductor layer, and an oxide layer. The p-type oxide semiconductor layer is disposed above the n-type gallium oxide epitaxial layer, contains an element different from gallium as a main component, and has p-type conductivity. The oxide layer is disposed between the n-type gallium oxide epitaxial layer and the p-type oxide semiconductor layer, and is made of a material different from gallium oxide and different at least partly from a material of the p-type oxide semiconductor layer.
    Type: Grant
    Filed: August 8, 2019
    Date of Patent: February 1, 2022
    Assignees: MITSUBISHI ELECTRIC CORPORATION, TOKYO INSTITUTE OF TECHNOLOGY
    Inventors: Yohei Yuda, Tatsuro Watahiki, Shinsuke Miyajima, Yuki Takiguchi
  • Patent number: 11237056
    Abstract: Novel monolithic cyclical reflective spatial heterodyne spectrometers (CRSHS) are presented. Monolithic CRSHS in accordance with the invention have a single frame wherein a flat mirror, roof mirror, and symmetric grating are affixed. The invention contains only fixed parts; the flat mirror, roof mirror, and symmetric grating do not move in relation to the frame. Compared to conventional CRSHS known in the art, the present invention enables much smaller and lighter CRSHS, requires less time and skill for maintenance, and is a better economic option. The disclosed invention may include fixed field-widening optical elements or a fiber-fed assembly.
    Type: Grant
    Filed: November 7, 2017
    Date of Patent: February 1, 2022
    Assignee: California Institute of Technology
    Inventor: Seyedeh Sona Hosseini
  • Patent number: 11234359
    Abstract: A method for soil moisture retrieval using multi-channel collaboration algorithm and passive microwave radiometry including: establishing mathematical relationship formula between brightness temperatures at any two channels according to microwave radiative transfer equation; collecting actual brightness temperatures of core channel and collaborative channels; selecting parameters to be retrieved including soil moisture value; giving a series of estimated values of parameters to be retrieved, calculating a series of predicted brightness temperatures of collaborative channels according to actual brightness temperature of core channel, microwave radiative transfer equation and mathematical relationship formula, comparing predicted brightness temperatures with actual brightness temperature, and determining soil moisture value.
    Type: Grant
    Filed: September 3, 2020
    Date of Patent: February 1, 2022
    Assignee: Aerospace Information Research Institute, Chinese Academy of Sciences
    Inventor: Tianjie Zhao
  • Patent number: 11234919
    Abstract: The present invention relates to a novel compound represented by following formula 2 produced by means of marine-derived fungus Penicillium sp. and a composition for improving skin wrinkles, enhancing elasticity and skin whitening using excellent collagen synthesis promoting activity and melanin production inhibitory activity of the novel compound. In formula 2, R1 is any one selected from the group consisting of H, OH, COOH, an alkyl having 1 to 6 carbon atoms and an alkoxy having 1 to 6 carbon atoms. R1 is any one selected from the group consisting of H, OH, COOH, an alkyl having 1 to 6 carbon atoms and an alkoxy having 1 to 6 carbon atoms. R2 is any one selected from the group consisting of H, OH, COOH, an alkyl having 1 to 6 carbon atoms and an alkoxy having 1 to 6 carbon atoms. R3 is any one selected from the group consisting of H, OH, COOH, an alkyl having 1 to 6 carbon atoms and an alkoxy having 1 to 6 carbon atoms.
    Type: Grant
    Filed: September 26, 2017
    Date of Patent: February 1, 2022
    Assignee: Korean Institute of Ocean Science & Technology
    Inventors: Heejae Shin, Gambang Pil, Hyiseung Lee, Jongseok Lee, Yeonju Lee, Jihoon Lee
  • Patent number: 11235054
    Abstract: Stable, immunogenic combination vaccine(s) comprising a mixture of antigens for prevention and prophylaxis of infections caused by Rotavirus, Poliomyelitis virus, Haemophilus influenzae, Corynebacterium diphtheriae, Clostridium tetani, Bordetella pertussis and Hepatitis B virus. A multivalent combination vaccine comprises i) significantly dose-reduced Salk-IPV or Sabin-IPV (IPV) antigens prepared by methods of formaldehyde inactivation and alum hydroxide adsorption resulting in maximum D-antigen recovery; ii) Injectable heat inactivated Rotavirus antigen(s) providing broad cross-protective immunity among human rotavirus strains; iii) Hib PRP-carrier protein conjugate having improved stability and immunogenicity; iv) whole cell pertussis antigen with improved immunogenicity and stability; and v) Homogenous fractions of Diphtheria and Tetanus toxoids.
    Type: Grant
    Filed: August 24, 2017
    Date of Patent: February 1, 2022
    Assignees: Serum Institute of India Private Limited, The United States of America, as Represented by the Secretary, Department of Health and Human Services
    Inventors: Rajeev Mhalasakant Dhere, Sambhaji Shankar Pisal, Jagdish Kamalaji Zade, Rajendra Narayan Sabale, Ravindra Bapurao Kadam, Abhijeet Sanjeev Kamble, Baoming Jiang, Roger Glass
  • Patent number: 11235032
    Abstract: The present disclosure provides a method of treating cancer with a priming dose of combination immunotherapy comprising IL-2 (e.g., extended-PK IL-2), an immune checkpoint inhibitor, a tumor targeting antibody or integrin-binding polypeptide, and optional cancer vaccine, administered prior to maintenance doses of immune checkpoint inhibitor therapy. The methods of the disclosure can be used to treat a broad range of cancer types.
    Type: Grant
    Filed: November 22, 2019
    Date of Patent: February 1, 2022
    Assignee: Massachusetts Institute of Technology
    Inventors: Chensu Wang, Karl Dane Wittrup, Darrell J. Irvine
  • Patent number: 11239211
    Abstract: An electronic device package structure including a substrate, a first circuit layer, a second circuit layer, an electronic device and an input/output device is provided. The first circuit layer includes a first conductive portion, a second conductive portion and a first curve portion located between the first conductive portion and the second conductive portion. At least a partial thickness of the first curve portion is greater than a thickness of the first conductive portion. The electronic device disposed on the second circuit layer is electrically connected to the second conductive portion of the first circuit layer. The input/output device disposed corresponding to the first conductive portion is electrically connected to the first conductive portion of the first circuit layer.
    Type: Grant
    Filed: January 7, 2020
    Date of Patent: February 1, 2022
    Assignee: Industrial Technology Research Institute
    Inventors: Wei-Kuo Han, Jing-Yao Chang, Tao-Chih Chang