Abstract: An apparatus includes processor(s) to: perform pre-processing operations including derive an audio noise level of speech audio of a speech data set, derive a first relative weighting for first and second segmentation techniques for identifying likely sentence pauses in the speech audio based on the audio noise level, and select likely sentence pauses for a converged set of likely sentence pauses from likely sentence pauses identified by the first and/or second segmentation techniques based on the first relative weighting; and perform speech-to-text processing operations including divide the speech data set into data segments representing speech segments of the speech audio based on the converged set of likely sentence pauses, and derive a second relative weighting based on the audio noise level for selecting words indicated by an acoustic model or by a language model as being most likely spoken in the speech audio for inclusion in a transcript.
Abstract: A method of making a composite membrane for a lithium-sulfur (Li—S) battery is described. The method includes providing a polymeric separator membrane; synthesizing a graphene oxide (GO) dispersion; and printing the GO dispersion onto at least one surface of the polymeric separator membrane. The GO coating includes a GO layer.
Abstract: A natural gas hydrate inhibitor having a structure of formula (1) or formula (2). The inhibitor of the present invention is synthesized on the basis of N-vinylpyrrolidone by introducing a new structural group to achieve terminal modification of the polymer chain, which thereby improves the inhibitory effect. wherein R is a C1-8 hydrocarbon group.
Type:
Application
Filed:
December 27, 2018
Publication date:
January 27, 2022
Applicant:
GUANGZHOU INSTITUTE OF ENERGY CONVERSION, CHINESE ACADEMY OF SCIENCES
Abstract: An apparatus includes processor(s) to: perform preprocessing operations of a segmentation technique including divide speech data set into data chunks representing chunks of speech audio, use an acoustic model with each data chunk to identify pauses in the speech audio, and analyze a length of time of each identified pause to identify a candidate set of likely sentence pauses in the speech audio; and perform speech-to-text operations including divide the speech data set into data segments that each representing segments of the speech audio based on the candidate set of likely sentence pauses, use the acoustic model with each data segment to identify likely speech sounds in the speech audio, analyze the identified likely speech sounds to identify candidate sets of words likely spoken in the speech audio, and generate a transcript of the speech data set based at least on the candidate sets of words likely spoken.
Abstract: The present invention relates to a recombinant microorganism for producing formic acid, which has a formate dehydrogenase 1 alpha subunit (FDH1?)-encoding endogenous gene deleted therefrom and an FDH1-encoding exogenous gene introduced thereinto, and a method for production of formic acid by using the microorganism.
Type:
Grant
Filed:
November 14, 2018
Date of Patent:
January 25, 2022
Assignee:
UNIST(ULSAN NATIONAL INSTITUTE OF SCIENCE AND TECHNOLOGY)
Inventors:
Yong Hwan Kim, Jung Ho Jang, Byoung Wook Jeon
Abstract: The present subject matter provides compositions, formulations, and methods for inhibiting, treating, or preventing aberrant angiogenesis in a subject.
Type:
Grant
Filed:
November 14, 2017
Date of Patent:
January 25, 2022
Assignee:
The Schepens Eye Research Institute, Inc.
Inventors:
Joseph F. Arboleda-Velasquez, Leo A. Kim, Patricia A. D'Amore
Abstract: A device is described for interrogating human skin using tight coupling between the transmitter and receiver of the millimeter waves (MMWs). Methods are provided to evaluate changes in the amplitude and/or phase of the transmitted MMWs in order to estimate the blood concentration of glucose. Using this device and the related methods, the blood glucose concentration or a change in the blood glucose concentration can be monitored for diagnosing diabetes mellitus and other metabolic disorders of carbohydrate metabolism characterized by either high blood glucose level (hyperglycemia) or low blood glucose level (hypoglycemia), as well as for monitoring (including self-monitoring) a metabolic disorder progression or an efficacy of treatment.
Type:
Grant
Filed:
August 25, 2015
Date of Patent:
January 25, 2022
Assignees:
CALIFORNIA INSTITUTE OF TECHNOLOGY, HUNTINGTON MEDICAL RESEARCH INSTITUTES
Abstract: The present application discloses compounds which are activators of autophagic flux and pharmaceutical compositions comprising said activators. It further discloses use of said compounds and pharmaceutical compositions in the treatment of neurodegenerative diseases, particularly proteinopathies and tauopathies such as Alzheimer's disease. It further discloses methods of enhancing autophagic flux.
Type:
Grant
Filed:
July 5, 2018
Date of Patent:
January 25, 2022
Assignees:
The Trustees of Columbia University in the City of New York, NY State Psychiatric Institute
Inventors:
Kirsten Alison Rinderspacher, Wai Yu, Karen Duff, Donald Landry, Shi-Xian Deng
Abstract: The present invention relates to recombinant adeno-associated virus (rAAV) delivery of polynucleotides for treating Duchenne Muscular Dystrophy resulting from the duplication of DMD exon 2. The invention provides rAAV products and methods of using the rAAV in the treatment of Duchenne Muscular Dystrophy.
Type:
Grant
Filed:
July 11, 2018
Date of Patent:
January 25, 2022
Assignee:
RESEARCH INSTITUTE AT NATIONWIDE CHILDREN'S HOSPITAL
Inventors:
Kevin Flanigan, Adeline Vulin-Chaffiol, Nicolas Wein
Abstract: A detecting device includes a first coil, a third coil, a second coil, and a fourth coil. The first coil generates a first magnetic field on a to-be-measured object. The third coil generates a third magnetic field under the to-be measured object. The second coil generates a second magnetic field. After the fourth coil receives the second magnetic field, a voltage is induced. The induced voltage is amplified by an amplify circuit to drive the third coil. The directions of the currents generated by the first coil and the third coil, respectively, are the same.
Type:
Grant
Filed:
December 19, 2017
Date of Patent:
January 25, 2022
Assignee:
INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE
Abstract: Provided are: a peptide for regulating reactivity to a serotonin reuptake inhibitor-based antidepressant; a vector and a pharmaceutical composition for preventing or treating depression, which comprise same; a method for screening for an antidepressant by evaluating the activity of mossy cells; and the like.
Type:
Grant
Filed:
July 26, 2019
Date of Patent:
January 25, 2022
Assignee:
DAEGU GYEONGBUK INSTITUTE OF SCIENCE AND TECHNOLOGY
Inventors:
Yong Seok Oh, Seo Jin Oh, Jin Hyuk Jang, Jeong Rak Park, Chang Hun Shin, Min Seok Jeong
Abstract: An ultraviolet C light-emitting diode including an n-type semiconductor layer, a p-type semiconductor layer, an active layer, a two-dimensional hole gas (2DHG) inducing layer, and an electron blocking layer is provided. The active layer is disposed between the n-type semiconductor layer and the p-type semiconductor layer, wherein a wavelength of a maximum peak of a spectrum emitted by the active layer ranges from 230 nm to 280 nm. The two-dimensional hole gas (2DHG) inducing layer is disposed between the active layer and the p-type semiconductor layer. A concentration of magnesium in the 2DHG inducing layer is less than 1017 atoms/cm3. The electron blocking layer is disposed between the p-type semiconductor layer and the 2DHG inducing layer. A concentration of magnesium in a part of the electron blocking layer adjacent to the 2DHG inducing layer is greater than 1019 atoms/cm3.
Type:
Grant
Filed:
August 31, 2020
Date of Patent:
January 25, 2022
Assignees:
Industrial Technology Research Institute, OPTO TECH CORP.
Inventors:
Chia-Lung Tsai, Hsueh-Hsing Liu, Chang Da Tsai
Abstract: A hydrogel includes: a partially or fully ionized cationic polymer and at least one selected from the group consisting of a partially or fully ionized anionic polymer and a low molecular weight compound having two or more anionic groups; or a partially or fully ionized anionic polymer and at least one selected from the group consisting of a partially or fully ionized cationic polymer and a low molecular weight compound having two or more cationic groups; and water. The hydrogel can be used for for producing clay with viscoelastic properties.
Type:
Grant
Filed:
January 17, 2019
Date of Patent:
January 25, 2022
Assignee:
DAEGU GYEONGBUK INSTITUTE OF SCIENCE AND TECHNOLOGY
Inventors:
Sang Won Jeong, Hyun-Chul Kim, Seong Jun Lee, Se Geun Lee
Abstract: A light absorber includes an insulating substrate; a reflective layer that is provided on the insulating substrate, that is composed of a metal, and that has conductivity; a conductive pattern that is disposed on the reflective layer and that has defined therein at least one first opening; a nano-antenna that is disposed on the reflective layer and that vertically overlaps the at least one first opening; and an insulating pattern having a first portion that is interposed between the reflective layer and the conductive pattern and having a second portion that is interposed between and completely fills a vertical space between the reflective layer and the nano-antenna so that the reflective layer, the conductive pattern, and the nano-antenna are electrically insulated from each other.
Type:
Grant
Filed:
April 30, 2018
Date of Patent:
January 25, 2022
Assignee:
Electronics and Telecommunications Research Institute
Inventors:
Sunghoon Hong, Hye Won Yoon, Mi Hyun Kim
Abstract: Embodiments of nanostructures comprising metal oxide and methods for forming the nanostructure on surfaces are disclosed. In certain embodiments, the nanostructures can be formed on a substrate made of a nickel titanium alloy, resulting in a nanostructure containing both titanium oxide and nickel oxide. The nanostructure can include a lattice layer disposed on top of a nanotube layer. The distal surface of the lattice layer can have a titanium oxide to nickel oxide ratio of greater than 10:1, or about 17:1, resulting in a nanostructure that promotes human endothelial cell migration and proliferation at the interface between the lattice layer and human cells or tissue. The nanostructure may be formed on the outer surface of an implantable medical device, such a stent or an orthopedic implant (e.g. knee implant, bone screw, or bone staple).
Type:
Grant
Filed:
September 21, 2018
Date of Patent:
January 25, 2022
Assignee:
Alfred E. Mann Institute for Biomedical Engineering at the University of Southern California
Inventors:
David Alvin Tyvoll, Nan Chen, Bharat Kumar Menon, Heather Michelle Grandin, Cesar Escobar Blanco
Abstract: A method for manufacturing a hollow camshaft is provided, and more particularly, a method for manufacturing a combined hollow camshaft by an axial-compression upsetting-deformation technique. The present method solves a problem that the current camshaft manufactured in an internal high-pressure expansion manner in the prior art has the insufficient locking force to cause the loosening of a cam. The method is as follows: a camshaft is formed by combining two independent units, namely a cam and a shaft tube. Non-circular countersinks are distributed on two sides of the cam. Thrust steps are formed on the shaft tube correspondingly. The cam is placed between the two thrust steps of the shaft tube. The locking force is applied to the cam by utilizing the thrust steps on the two sides of the cam based on thermal expansion and contraction. Simultaneously, the thrust steps lock the cam with the countersinks.
Abstract: A rotationally compliant bearing roller assembly having a roller, at least one bearing member operably coupled to a base configured to support rotational movement about a rotational axis; and a rotary compliant joint interconnecting the at least one bearing member to the roller. The rotary compliant joint having a first compliance in a rotational direction about the rotational axis to permit movement of the roller in the rotational direction relative to the at least one bearing member, such that the first compliance being greater than a friction induced compliance of the at least one bearing member in the rotational direction. The compliant joint having a second compliance in a direction orthogonal to the rotational direction, such that the second compliance being less than the first compliance.
Type:
Grant
Filed:
October 5, 2020
Date of Patent:
January 25, 2022
Assignees:
THE REGENTS OF THE UNIVERSITY OF MICHIGAN, Korea Institute of Machinery & Materials
Inventors:
Chinedum E. Okwudire, Xin Dong, Dongwoo Kang
Abstract: The present invention generally relates to compositions and methods for forming droplets and/or emulsions. In some embodiments, the compositions and methods comprise two or more components miscible at a first temperature and immiscible at a second temperature, dispersed in an outer phase.
Type:
Grant
Filed:
February 25, 2019
Date of Patent:
January 25, 2022
Assignee:
Massachusetts Institute of Technology
Inventors:
Timothy M. Swager, Edmundo Daniel Blankschtein, Lauren Dell Zarzar, Vishnu Sresht, Ellen Sletten, Julia Ann Kalow
Abstract: The present invention relates to inhibin analogs, their method of production and their use in the treatment and prophylaxis of disease or conditions associated with reduced levels of inhibin and activin-mediated signaling.
Abstract: Provided is an apparatus for generating a vibrotactile sensation. The apparatus for generating a vibrotactile sensation includes a light source generating light, a vibration layer generating a vibration by receiving the light, a vibration detection unit disposed adjacent to the vibration layer to detect a vibration signal of the vibration layer, and a control unit connected to the vibration detection unit to determine the vibration of the vibration layer by using the vibration signal. Here, the vibration layer includes a thermo-elastic layer that has a first thermal expansion coefficient and a photo-thermal conversion layer that is disposed on the thermo-elastic layer and has a second thermal expansion coefficient less than the first thermal expansion coefficient.
Type:
Grant
Filed:
August 11, 2020
Date of Patent:
January 25, 2022
Assignee:
Electronics and Telecommunications Research Institute