Abstract: The present invention includes methods of treating patients with acute myeloid leukemia across a range of genetic subtypes with DHODH inhibitors, such as 6-fluoro-2-(2?-fluoro-[1,1?-biphenyl]-4-yl)-3-methylquinoline-4-carboxylic acid).

Abstract: Disclosed herein are an apparatus and method for recommending federated learning based on recognition model tendency analysis. The method for recommending federated learning based on recognition model tendency analysis in a server device may include analyzing the tendency of a recognition model trained using reinforcement learning by each of multiple user terminals, grouping the multiple user terminals according to the tendency of the recognition model, and transmitting federated-learning group information including information about other user terminals grouped together with at least one of the multiple user terminals.

Abstract: The present disclosure relates to a microorganism detection apparatus using a dielectrophoresis (DEP) force.

Abstract: In certain aspects, the present disclosure relates to the insight that a polypeptide comprising a ligand-binding portion of the extracellular domain of activin-like kinase I (ALK1) polypeptide may be used to inhibit angiogenesis in vivo, particularly in mammals suffering angiogenesis-related disorders. Additionally, the disclosure demonstrates that inhibitors of ALK1 may be used to increase pericyte coverage in vascularized tissues, including tumors and the retina. The disclosure also identifies ligands for ALK1 and demonstrates that such ligands have pro-angiogenic activity, and describes antibodies that inhibit receptor-ligand interaction.

Abstract: Described are methods for providing personalized medicine for the treatment of B cell malignancies including lymphoma. The methods make use of Chimeric Antigen Receptor (CAR) technology.

Abstract: Provided are an image encoding method and device. When carrying out image encoding for a block within a slice, at least one block in a restored block of the slice is set as a reference block. When this is done, the encoding parameters of the reference block are distinguished, and the block to be encoded is encoded adaptively based on the encoding parameters.

Abstract: In some embodiments, a mass spectrometry tag may comprise a linker region, a mass balance region, and a reporter region. The mass spectrometry tag may be configured to fragment in a mass spectrometer via an energy dependent process to produce multiple reporter molecules. For example, the reporter region of the tag may be configured to produce at least two reporter molecules via fragmentation. In some embodiments, one or more regions of the tag may comprise at least one heavy isotope. In some such embodiments, the ability to fragment into multiple reporter molecules as well as the placement and/or number of heavy isotope(s) allows the mass spectrometry tag to be distinguished from other similar mass spectrometry tags. In some such embodiments, the ability to distinguish between tags having the same or substantially similar total mass to charge ratio and reporter region mass may allow the system to have a greater multiplexing capacity than conventional systems.

Abstract: The present application provides a method for testing the coverage effect of a VHF communication base station, including: a server sending preset test parameter information to a mobile station, sending a first start test instruction to the mobile station and at least one base station, and receiving first audio data and first location information sent by the at least one base station, and second audio data and second location information sent by the mobile station. By using the mobile stations to send or receive audio data at different distances to a temporary VHF communication base station, it is possible to accurately determine a coverage distance of the temporary VHF communication base station and a transmission effect of the audio data at different communication distances.

Abstract: The present disclosure relates to compositions and methods for the diagnosis and treatment or prevention of cancers, particularly cancers that exhibit elevated expression of FOXA1 and/or FOXA1 gene targets, such as certain breast, liver and/or prostate cancers, including luminal and/or ER-positive forms of breast cancer. Three previously identified adenosine receptor antagonists, CGS-15943, MRS-1220 and SCH-58261, as well as furan ring moiety-possessing derivatives of CGS-15943 are specifically provided for killing cancer cells in a manner that appears to involve activation of the aryl hydrocarbon receptor (AHR) by such compounds. The instant disclosure therefore provides for selecting and/or administering CGS-15943, MRS-1220, SCH-58261 and/or a furan-possessing derivative of CGS-15943, MRS-1220 and/or SCH-58261 as a therapeutic agent to target a cancer cell and/or subject having or at risk of developing a cancer.

Abstract: Disclosed herein are genetically modified herpesviruses for the treatment of cancer. Also provided are methods of treating cancer using genetically modified herpesviruses.

Abstract: The invention relates to a carburizing bearing steel and a preparation method thereof. The carburizing bearing steel of the invention comprises: 0.18˜0.24 wt % of C, 0.4˜0.6 wt % of Cr, 0.20˜0.40 wt % of Si, 0.40˜0.70 wt % of Mn, 1.6˜2.2 wt % of Ni, 0.15˜0.35 wt % of Mo, 0.001˜0.01 wt % of S, 0.001˜0.015 wt % of P, 0˜0.20 wt % of Nb, 0˜0.20 wt % of V and the remaining is iron, wherein the contents of Nb and V are not 0 at the same time. In the invention, an appropriate amount of Nb and V is added in combination with other elements so as to refine the grain size, inhibit the generation of large granular carbides in the steel during carburization and improve the uniformity of the microstructure of steel materials, thus further enhancing the contact fatigue life of the carburizing bearing steel.

Abstract: A fund tracking system, a fund tracking method and a graphic user interface are provided. The fund tracking method is used to track a target fund. The fund tracking method includes the following steps. Several ETF asset classes are obtained according to a fund benchmark index of the target fund. Several representative ETFs are obtained according to the ETF asset classes. A simulated investment portfolio is generated according to the representative ETFs. Whether the simulated investment portfolio meets a verification condition is verified. If the simulated investment portfolio meets the verification condition, the simulated investment portfolio is outputted.

Abstract: A switching device in accordance with the present invention includes a first electrode and a second electrode, and the second electrode includes a body part and a cantilever connected to the body part. In addition, one end of a the cantilever comes into contact with the first electrode by an electrostatic force generated by a voltage applied to the first electrode and the second electrode, and the one end of the cantilever is separated from the first electrode due to heat generated by a voltage applied to both ends of the body part. In addition, the second electrode may include a 2-1 electrode, a 2-2 electrode, and an engineered beam connected in between.

Abstract: Disclosed is an image analysis system which includes a first analyzer and a second analyzer. The first analyzer generates first features by encoding images through a first model and adjusts a weight of the first model based on the first features. The second analyzer generates second features based on the first features by encoding the images through a second model, classifies the second features into classes, respectively, and adjusts a weight of the second model based on mutual information and a correlation between a first class among the classes which features corresponding to an original image group from among the second features are classified as and a second class among the classes which features corresponding to an augmentation group of the original image group from among the second features are classified as.

Abstract: The present invention provides a TiAl-based alloy, including: Al: 41 to 43 at %; Fe: 0 to 2.5 at %; Ni: 0 to 2.5 at %; Mo: 0 to 2.0 at %; W: 0 to 2.0 at %; Cr: 0 to 4.5 at %; Mn: 0 to 5.5 at %; V: 0 to 10 at %; Nb: 0 to 10 at %; C: 0.3 to 0.7 at %; and a remainder consisting of Ti and inevitable impurities, in which an alloy element parameter “P=(41.5?Al)/3+Fe+Ni+Mo+W+0.5 Cr+0.4 Mn+0.2 V+0.2 Nb—C” is in a composition range of 1.1 to 1.9, and the TiAl-based alloy has a microstructure consisting of a ? phase of 5 to 30 area %, a ? phase of 0.5 to 5 area %, and a lamellar structure occupying a remaining part.

Abstract: A preparation method of a carbon-based selenium-enriched fertilizer for rice is disclosed. The preparation method of the carbon-based selenium-enriched fertilizer for rice includes planting a selenium-enriched plant material; collecting and concentrating a selenium-enriched extracting solution; preparing modified selenium-enriched biomass charcoal from the tertiary residues; and preparing the carbon-based selenium-enriched fertilizer. In the present disclosure, active organic selenium enriched and generated by plant is compounded with the biomass charcoal, so that the fixation and loss of the active selenium in soil are reduced, and the utilization efficiency of the selenium fertilizer is improved.

Abstract: A multimodal inspection system (MIS) is disclosed herein. The MIS may use one or more modalities to inspect a sample. Some of the modalities include, but are not limited to, Raman, visible (VIS), terahertz (THz) spectroscopy, longwave infrared (LWIR), shortwave infrared (SWIR), laser profilometry (LP), electromagnetic interference (EMI) near field probing, and/or, Millimeter Wave (MMW) radar.

Abstract: A decision engine includes: a genetic algorithm framework including a knowledge base of standard configurations, a candidate selector generator and a selector to select a candidate configuration from a plurality of preferred standard configurations in response to the candidate selector generator; a parallelized reasoning framework including an attack surface reasoning algorithm module to compute the security and cost tradeoffs of an attack surface associated with each candidate configuration; and a user interface framework including a web service engine where users can interact and provide feedback on direction of an evolution used in a genetic algorithm search for evolving defenses.

Abstract: Disclosed is a multi-channel atomic magnetic detector (100), including at least one detection assembly, with each detection assembly including a plurality of detection air chambers (130) in the same plane and a light-splitting member (110) for allocating polarized beams from a light source (180) to each detection air chamber (130) in the detection assembly, wherein the plurality of detection air chambers (130) of each detection assembly are arranged in a centrally symmetric manner or an axially symmetric manner relative to the light-splitting member (110). The multi-channel atomic magnetic detector (100) has a high detection density and is beneficial for noise reduction.

Abstract: A bubble-column-humidification apparatus includes a humidifier chamber configured to receive the feed liquid from a feed-liquid source. A bubble distributor is contained in the humidifier chamber; and a humidifier bath of the feed liquid is also contained in the humidifier chamber above the bubble distributor. The feed liquid forms a continuous and majority phase of the humidifier bath and fills a majority of the humidifier chamber, which has a width at least twice as great as its height. A lower gas region is located below the bubble distributor and the humidifier bath in the humidifier chamber and is configured to receive a carrier gas from a carrier-gas source and to disperse the carrier gas through the bubble distributor. The carrier gas in the lower gas region has a pressure greater than the hydrostatic pressure of the humidifier bath.