Abstract: The present disclosure provides a novel method for monitoring the conversion of oral precancerous lesions to oral cancers, including monitoring changes in oral exosome concentrations in a subject, thereby determining the state of the disease and the risk of carcinogenesis. The disclosure also relates to a detection kit for use in the above method.
Type:
Application
Filed:
July 19, 2021
Publication date:
January 13, 2022
Applicant:
RESEARCH INSTITUTE AT NATIONWIDE CHILDREN'S HOSPITAL
Inventors:
Li Chen, Yu Zhou, David Brigstock, Gail Besner
Abstract: A spectrometer includes a transparent substrate including a first surface and a second surface that face each other and are substantially parallel to each other; a slit provided on the first surface and through which light is incident onto the transparent substrate; a spectrum optical system including metasurface including a plurality of nanostructures that are two-dimensionally arranged and satisfy a sub-wavelength scattering condition, wherein the metasurface includes a focusing metasurface which includes first nanostructures of the plurality of nanostructures, and is configured to reflect, disperse, and focus the light incident thereon through the slit, at different angles based on respective wavelengths; and a sensor configured to receive the light from the focusing metasurface. When L is a total length of an optical path from the slit to the sensor and D is a thickness of the transparent substrate, L and D satisfy the following inequality: L/D>3.
Type:
Application
Filed:
September 27, 2021
Publication date:
January 13, 2022
Applicants:
SAMSUNG ELECTRONICS CO., LTD., CALIFORNIA INSTITUTE OF TECHNOLOGY
Inventors:
Seunghoon Han, Amir Arbabi, Andrei Faraon, Ehsan Arbabi
Abstract: Systems and methods for controlling a vehicle with respect to an intersection are disclosed. In one embodiment, a method of controlling a vehicle with respect to an intersection, includes determining a distance of the vehicle with respect to the intersection, wherein the intersection includes a traffic light, determining a velocity of the vehicle, and receiving traffic light state information regarding the traffic light. The method also includes calculating, based on the distance of the vehicle to the intersection, the velocity of the vehicle, and the traffic light state information, a zone of interest with respect to the traffic light. The method further includes manipulating the velocity of the vehicle to modify a size of the zone of interest when a current trajectory of the vehicle will cause the vehicle to enter the zone of interest.
Type:
Application
Filed:
July 10, 2020
Publication date:
January 13, 2022
Applicant:
Toyota Research Institute, Inc.
Inventors:
Yutaka Taruoka, Ryan Marcotte, Hai Jin, Hiroshi Nakamura
Abstract: An operation method of a communication node in a millimeter-wave based communication system may comprise when a first communication path between the second base station and the terminal connected to the first base station is not established, transmitting a radio resource control (RRC) request message requesting establishment of the first communication path to the second base station via the first base station; receiving an RRC response message from the second base station via the first base station, the RRC response message being a response to the RRC request message; and establishing the first communication path based on the RRC response message.
Type:
Application
Filed:
September 27, 2021
Publication date:
January 13, 2022
Applicant:
ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTE
Abstract: The present disclosure relates to compositions and methods for the diagnosis and treatment or prevention of cancers, particularly cancers that exhibit elevated expression of SLC26A2, such as certain ovarian, endometrial, brain, bone, and lung cancers, as well as melanoma. A previously identified vanadium-containing compound, bis(maltolato)oxovanadium(IV) (BMOV), specifically provided for killing of SLC26A2 expressing cancer cells in a SLC26A2-dependent manner. The instant disclosure therefore provides for selecting and/or administering BMOV and related vanadium-containing compounds as a therapeutic agent to target a cancer cell and/or subject having or at risk of developing a cancer. Methods and compositions for therapies that include such compounds are also provided.
Type:
Application
Filed:
November 13, 2019
Publication date:
January 13, 2022
Applicants:
THE BROAD INSTITUTE, INC., DANA-FARBER CANCER INSTITUTE, INC., INSTITUTO CARLOS SLIM DE LA SALUD, A.C.
Inventors:
Steven CORSELLO, Ryan SPANGLER, Rohith NAGARI, Todd GOLUB
Abstract: Ferrimagnetic oscillator magnetometers do not use lasers to stimulate fluorescence emission from defect centers in solid-state hosts (e.g., nitrogen vacancies in diamonds). Instead, in a ferrimagnetic oscillator magnetometer, the applied magnetic field shifts the resonance of entangled electronic spins in a ferrimagnetic crystal. These spins are entangled and can have an ensemble resonance linewidth of approximately 370 kHz to 10 MHz. The resonance shift produces microwave sidebands with amplitudes proportional to the magnetic field strength at frequencies proportional to the magnetic field oscillation frequency. These sidebands can be coherently averaged, digitized, and coherently processed, yielding magnetic field measurements with sensitivities possibly approaching the spin projection limit of 1 attotesla/?{square root over (Hz)}. The encoding of magnetic signals in frequency rather than amplitude relaxes or removes otherwise stringent requires on the digitizer.
Type:
Application
Filed:
May 12, 2021
Publication date:
January 13, 2022
Applicant:
Massachusetts Institute of Technology
Inventors:
John F. Barry, Reed Anderson Irion, Jessica Kedziora, Matthew Steinecker, Daniel K. Freeman, Danielle A. Braje
Abstract: A photonic parallel network can be used to sample combinatorially hard distributions of Ising problems. The photonic parallel network, also called a photonic processor, finds the ground state of a general Ising problem and can probe critical behaviors of universality classes and their critical exponents. In addition to the attractive features of photonic networks—passivity, parallelization, high-speed and low-power—the photonic processor exploits dynamic noise that occurs during the detection process to find ground states more efficiently.
Type:
Application
Filed:
April 26, 2021
Publication date:
January 13, 2022
Applicant:
Massachusetts Institute of Technology
Inventors:
Charles ROQUES-CARMES, Yichen Shen, Li JING, Tena DUBCEK, Scott A. SKIRLO, Hengameh BAGHERIANLEMRASKI, Marin SOLJACIC
Abstract: A method, a processing device and a display system for information display are provided. The system includes a display being light transmissive, at least one first information extraction device, at least one second information extraction device, and a processing device. The processing device is connected to the display, the first information extraction device and the second information extraction device. The first information extraction device is configured to extract a user's position information and posture information. The second information extraction device is configured to extract a target object's position information and posture information.
Type:
Application
Filed:
November 30, 2020
Publication date:
January 13, 2022
Applicant:
Industrial Technology Research Institute
Inventors:
Yu-Hsuan Su, Tzu-Yi Yu, Yu-Hsiang Tsai, Kuan-Ting Chen
Abstract: Disclosed are methods and apparatuses for image data encoding/decoding. A method for decoding a 360-degree image includes the steps of: receiving a bitstream obtained by encoding a 360-degree image; generating a prediction image by making reference to syntax information obtained from the received bitstream; adding the generated prediction image to a residual image obtained by dequantizing and inverse-transforming the bitstream, so as to obtain a decoded image; and reconstructing the decoded image into a 360-degree image according to a projection format. Therefore, the performance of image data compression can be improved.
Abstract: Aspects of the application relate to methods and systems for evaluating treatment response by measuring treatment-induced changes at the single cell level. The disclosure provides methods for isolating single cells that are primary cancer cells, including primary cancer cells from solid tumors, and detecting in minutes to hours from their removal from the body the response of such cells to anti-cancer agents such as radiation, small molecules, biologies, DNA damaging agents and the like.
Type:
Application
Filed:
November 14, 2019
Publication date:
January 13, 2022
Applicants:
Dana-Farber Cancer Institute, Inc., Massachusetts Institute of Technology
Inventors:
Keith Ligon, Seth William Malinowski, Scott R. Manalis, Selim Olcum, Robert J. Kimmerling, Nicholas L. Calistri, David Weinstock, Mark Murakami, Mark M. Stevens
Abstract: Aspects of the present application relate to techniques of diagnosing whether a pathogen (e.g., SARS-CoV-2) is present in a subject using infrared (IR) spectroscopy and machine learning techniques. The techniques use spectral data obtained from performing IR spectroscopy on a biological sample (e.g., saliva or nasal sample, or genetic material extracted therefrom) to generate a set of feature values. The feature values are provided as input to a machine learning model to obtain output indicating whether the pathogen is present in the biological sample. The output of the machine learning model may be used to determine a diagnosis result for a subject.
Type:
Application
Filed:
July 6, 2021
Publication date:
January 13, 2022
Applicants:
Massachusetts Institute of Technology, Mohammed VI Polytechnic University, Laboratoire Anoual
Abstract: The vertical counterforce loading device includes a concrete support member, four transfer components, four connection components, a vertical force transmission component and a load test soil layer. The concrete support member is formed by pouring and concreting below the load test soil layer. The four transfer components are divided into two groups to be symmetrically and parallelly anchored in the concrete support member. The vertical force transmission component includes a load plate, a jack, a primary beam and a secondary beam arranged in sequence from bottom to top. The load plate is installed on the load test soil layer. The number of the secondary beams is two, and the two secondary beams are connected crosswise to both ends of the primary beam. The end portions of the two secondary beams are respectively connected to second ends of the four connection components through reinforcement components.
Type:
Application
Filed:
June 22, 2021
Publication date:
January 13, 2022
Applicant:
China Institute of Water Resources and Hydropower Research
Abstract: A spherical body drive type movement device 10 includes rotary bodies 14, 15, and 16 rotating n number of driving spherical bodies 11, 12, and 13 by being rotationally driven in a state of being in contact from two different directions with each of the driving spherical bodies 11, 12, and 13, and moves on a traveling surface G. The rotary bodies 14, 15, and 16 come into contact with the driving spherical bodies 11, 12, and 13 at positions higher than centers P1, P2, and P3 of the driving spherical bodies 11, 12, and 13 in contact and inside a virtual inverted n-gonal pyramid H or, at positions higher than the centers P1, P2, and P3 of the driving spherical bodies 11, 12, and 13 in contact and on lateral faces ?, ?, and ? of the virtual inverted n-gonal pyramid H.
Abstract: A sensor tube according to the present invention comprises: a tubular body for connecting two connection pipes to each other, wherein the two connection pipes are connected to a humidity sensor, so that the connection pipes transfer steam to the humidity sensor by using circulating air or air discharged from the humidity sensor flow in the connection pipes; and a cover surrounding at least a part of the outer surface of the body to prevent foreign substances having a predetermined size or larger from passing, wherein the body is formed as a porous sintered body which allows stream to be introduced from the outside of the body into the body and be transferred by the circulating air.
Type:
Application
Filed:
October 11, 2019
Publication date:
January 13, 2022
Applicant:
KOREA ATOMIC ENERGY RESEARCH INSTITUTE
Inventors:
Yeon Sik KIM, Tae Soon KWON, Dong Jin EUH, Hae Seob CHOI, Woo Shik KIM
Abstract: An image encoding/decoding method and apparatus are provided. An image decoding method performed by an image decoding apparatus according to the present invention may comprise deriving an intra-prediction mode of a current block, and performing intra-prediction for the current block based on the intra-prediction mode. The deriving of the intra-prediction mode may comprise decoding a predetermined mode sameness indicator.
Type:
Application
Filed:
May 13, 2021
Publication date:
January 13, 2022
Applicants:
Electronics and Telecommunications Research Institute, Industry-University Cooperation Foundation Korea Aerospace University, Hanbat National University Industry-Academic Cooperation Foundation
Inventors:
Jin Ho LEE, Sung Chang LIM, Jung Won KANG, Hyun Suk KO, Ha Hyun LEE, Dong San JUN, Seung Hyun CHO, Hui Yong KIM, Jae Gon KIM, Do Hyeon PARK, Jin Soo CHOI, Hae Chul CHOI
Abstract: A method and apparatus for performing binaural rendering of an audio signal are provided. The method includes identifying an input signal that is based on an object, and metadata that includes distance information indicating a distance to the object, generating a binaural filter that is based on the metadata, using a binaural room impulse response, obtaining a binaural filter to which a low-pass filter (LPF) is applied, using a frequency response control that is based on the distance information, and generating a binaural-rendered output signal by performing a convolution of the input signal and the binaural filter to which the LPF is applied.
Type:
Application
Filed:
March 12, 2021
Publication date:
January 13, 2022
Applicant:
Electronics and Telecommunications Research Institute
Inventors:
Yong Ju LEE, Jae-hyoun YOO, Mi Suk LEE, Kyeongok KANG, Dae Young JANG
Abstract: An image decoding method is disclosed in the present specification. A method of decoding an image, the method may comprises determining whether to perform a context update for a first syntax element of a current block, updating, on the basis of the determination, a context for entropy decoding of the first syntax element and generating, on the basis of the updated context, a bin for the first syntax element, and wherein whether to perform the context update is determined on the basis of the number of pre-decoded predetermined syntax elements for the current block.
Type:
Application
Filed:
November 21, 2019
Publication date:
January 13, 2022
Applicants:
Electronics and Telecommunications Research Institute, CHIPS&MEDIA, INC
Inventors:
Sung Chang LIM, Jung Won KANG, Ha Hyun LEE, Jin Ho LEE, Hui Yong KIM, Dae Yeon KIM, Wook Je JEONG, Hyun Gyu KIM
Abstract: Provided is a machining method for improving machining quality for a machining target by minimizing vibrations occurring during machining of each machining region, deformation of a shape of the machining region, and a position error of the machining region by selecting a machining path in consideration of the number of fixing jigs and a distance between jigs at each machining region.
Type:
Application
Filed:
November 18, 2019
Publication date:
January 13, 2022
Applicant:
KOREA INSTITUTE OF INDUSTRIAL TECHNOLOGY
Inventors:
Tae Gon KIM, Hyo Young KIM, Seok Woo LEE
Abstract: An efficient simulated moving bed device and an efficient simulated moving bed process are provided. The efficient simulated moving bed device comprises an adsorption bed, a raw material feeding system, a desorbent feeding system, a circulating system, an extract system, a raffinate system, a program-controlled valve group, and an automatic control system.
Type:
Application
Filed:
July 5, 2019
Publication date:
January 13, 2022
Applicant:
Inner Mongolia Yitai Coal-based New Materials Research Institute Co., Ltd.