Abstract: A method and system for determining an irradiation dose. The method for determining the irradiation dose includes determining a pixel having a biological feature in a region of interest in a radiotherapy simulated locating image by using a retrospective label; extracting a local radiomics feature based on the pixel having the biological feature, in which the local radiomics feature includes a grayscale histogram intensity, a tumor shape feature, a textural feature, a Laplacian of Gaussian filtering feature, and a wavelet feature; acquiring the local radiomics features to be measured; identifying a positive region having the local radiomics features to be measured based on the local radiomics features; performing three-dimensional reconstruction for the peripheral boundary of the positive region to determine a three-dimensional image.

Abstract: Provided is an amplification circuit for amplifying an input signal. The amplification circuit includes an input stage including an input matching circuit that receives the input signal and an input attenuation circuit that attenuates a gain for the input signal outside an operating frequency band of the amplification circuit, a transistor that amplifies the input signal provided from the input stage, and an output stage including an output matching circuit that receives a signal amplified by the transistor and an output attenuation circuit that attenuates the gain for the input signal outside the operating frequency band of the amplification circuit, and the input attenuation circuit includes a first resistor and a second resistor that are connected to a ground voltage, a first passive element connected between the input matching circuit and the second resistor, and a second passive element connected between the first passive element and the first resistor.

Abstract: Methods and compositions are provided that can be used to vaccinate against and treat HIV. Specifically contemplated are vaccine compositions and methods of using these compositions treat HIV in patients. Aspects of the disclosure relate to an anti-CD40 antibody-HIV antigen fusion protein comprising (i) an anti-CD40 heavy chain (HCD40)-HIV antigen (Ag) fusion protein comprising the formula: HCD40-Ag, wherein Ag is a polypeptide with at least 80% sequence identity to SEQ ID NO:1; and (ii) an anti-CD40 light chain (LCD40).

Abstract: Disclosed herein is an aerogel made from a polyhydroxy benzene compound crosslinked with formaldehyde. The aerogel is dry and has a first volume and wherein the aerogel can be exposed to a liquid and be re-dried in a gas while retaining at least 70% of the first volume.

Abstract: A gyro measurement while drilling system, which includes a strapdown inertial unit, a filtering and level conversion module, a data acquisition and data communication module, a driving mechanism, a driving control module and a navigation computer. A gyro measurement while drilling method, which is used in the measurement while drilling system and includes one or a combination of the following methods: a full parameter variable compensation method, an initial alignment algorithm and a continuous measurement while drilling method. The system and method of the present disclosure can meet the most demanding application scenarios in the field of petroleum drilling measurement, i.e.

Abstract: The present disclosure provides a rapid, scalable, and high-throughput method of identifying the precise regions in a receptor protein which are involved in binding of a molecule of interest. The method of the instant disclosure is useful where the crystal structure of a protein of interest is not available. Also provided are surface display libraries, and methods of making the same.

Abstract: A scent visualization system may comprise a display apparatus for generating a target image including a target object; an olfactory sensor for detecting a scent; and a scent visualization apparatus for generating target associative visualization information that reminds the scent from the target image received from the display apparatus and sensing information received from the olfactory sensor, and generating an associative image by combining the target associative visualization information and the target image. Therefore, a low-cost, high-efficiency, high-utilization, and high-convenience scent visualization system can be provided.

Abstract: A method for separation and enrichment of lithium includes the following steps: pretreatment: diluting and filtering salina aged brine to obtain pretreated brine; separation: separating the pretreated brine via a nanofiltration separation system to obtain nanofiltration permeate and nanofiltration concentrate; first concentration: carrying out first concentration on the nanofiltration permeate via a reverse osmosis system to obtain reverse osmosis concentrate and reverse osmosis permeate; second concentration: carrying out second concentration on the reverse osmosis concentrate via an electrodialysis system to obtain electrodialysis concentrate and electrodialysis permeate, and the electrodialysis concentrate is solution enriching lithium ions.

Abstract: An operation method of a first communication node in a communication system includes receiving a signal from a second communication node; demodulating the signal to obtain LLR values; calculating a first codeword based on the LLR values; selecting error patterns from among all error patterns based on Hamming weights; generating second codewords by applying the first codeword to each of the selected error patterns; and determining a codeword having a highest similarity to the first codeword among the second codewords as an optimal codeword.

Abstract: The invention provides structurally-constrained peptides by hydrocarbon stapling of a BCL9 HD2 helix for use as a therapeutic agent. The invention further provides methods and kits for use of the structurally-constrained peptide of the instant invention. The invention is based, at least in part, on the results provided herein demonstrating that hydrocarbon stapled helical peptides display excellent proteolytic, acid, and thermal stability, restore the native helical structure of the peptide, possess superior pharmacokinetic properties compared to the corresponding unmodified peptides, and are highly effective in binding to ?-catenin in vitro, in cellulo, and in vivo, disrupting the BCL9/?-catenin interaction, and thereby interfering with deregulated Wnt/?-catenin signaling for therapeutic benefit in a variety of human diseases including human cancer.

Abstract: An n-type semiconductor layer has a single-crystal structure and is made of a wide-gap semiconducting material. A p-type semiconductor layer is provided on the n-type semiconductor layer and made of a material different from the aforementioned wide-gap semiconducting material, and has either a microcrystalline structure or an amorphous structure. An electrode is provided on at least one of the n-type semiconductor layer and the p-type semiconductor layer.

Abstract: Embodiments of the disclosure relate to methods and systems for modeling, controlling and computer-platform implementation of a Synthetic Reserve Provisioning System (SRPS) needed to aggregate and integrate small devices closer to consumers, referred to as Distributed Energy Resources (DERs). This know-how is based on data-driven physics-based modeling and it supports the dispatch and scheduling of DERs so that they can participate in system level provision of electricity service. An SRPS generally comprises multiple levels of consumer aggregators (Synthetic Reserve Provisioning (SRP) modules) which interact by exchanging well-defined information about provable consumer characteristics and their own loading and pricing conditions. Three different SRPS designs are described. They differ with respect to implementation requirements for communications, control, technical and economic risks assumed by different SRP modules.

Abstract: An information processing apparatus includes: a corresponding data calculation unit configured to determine importance of each sample in accordance with a difference between a plurality of pieces of observation information observed when an input is given to an observation target and data of a second type generated by a simulator that simulates the observation target based on a sample of a parameter with respect to a plurality of samples and data of a first type indicating the input, and a degree of influence of the sample on distribution of parameters, and then calculate data that corresponds to the distribution of the parameters; a new parameter sample generation unit configured to generate a new sample of the parameters in accordance with predetermined processing using the data that corresponds to the distribution of the parameters; and an iteration control unit configured to perform control so as to repeat the above processing.

Abstract: This application discloses a polymer ultraviolet absorbent and preparation method and application thereof. The synthesis process of the polymer ultraviolet absorbent does not require additional organic solvents, and the reaction by-product is high-purity ethanol, which is relatively economical. green, efficient and environmentally friendly. The polymer ultraviolet absorbent has good water solubility, is convenient to use, safe and non-toxic, and has excellent ultraviolet absorption effect.

Abstract: In various embodiments methods for the treatment or prophylaxis of an age-related and/or pathology-associated increase in intestinal barrier permeability are provided. In certain embodiments the methods comprise administering to a mammal in need thereof an effective amount of one or more agent(s) that inhibit superoxide or hydrogen peroxide production from the outer ubiquinone-binding site of complex III of the mitochondrial electron transport chain (site IIIQo).

Abstract: An encoding apparatus and a decoding apparatus in a transform between a Modified Discrete Cosine Transform (MDCT)-based coder and a different coder are provided. The encoding apparatus may encode additional information to restore an input signal encoded according to the MDCT-based coding scheme, when switching occurs between the MDCT-based coder and the different coder. Accordingly, an unnecessary bitstream may be prevented from being generated, and minimum additional information may be encoded.

Abstract: An audio signal encoding and decoding method using a neural network model, a method of training the neural network model, and an encoder and decoder performing the methods are disclosed. The encoding method includes computing the first feature information of an input signal using a recurrent encoding model, computing an output signal from the first feature information using a recurrent decoding model, calculating a residual signal by subtracting the output signal from the input signal, computing the second feature information of the residual signal using a nonrecurrent encoding model, and converting the first feature information and the second feature information to a bitstream.

Abstract: A lead frame package including first conductive layer, first electronic component, lead frames, second conductive layer and package body. First conductive layer has conductive carriers. First electronic component has first pins. Lead frames and first pins are respectively electrically connected to conductive carriers. Second conductive layer has conductive joints respectively electrically connected to lead frames so as to be electrically connected to at least a part of conductive carriers via lead frames. Package body encapsulates first conductive layer, first electronic component, and lead frames. First conductive layer and second conductive layer are located on two opposite sides of first electronic component, respectively.

Abstract: The present invention relates to a rear lamp which has a 3D light distribution effect so as to represent a sense of depth by the infinity mirror effect and, more specifically, to a rear lamp configured to produce a movable light distribution image.

Abstract: Provided is a semiconductor package structure including a redistribution layer (RDL) structure, a chip, an electronic device and a stress compensation layer. The RDL structure has a first surface and a second surface opposite to each other. The chip is disposed on the first surface and electrically connected to the RDL structure. The electronic device is disposed in the RDL structure, electrically connected to the chip, and includes a dielectric layer disposed therein. The stress compensation layer is disposed in or outside the RDL structure. The dielectric layer provides a first stress between 50 Mpa and 200 Mpa in a first direction perpendicular to the second surface, the stress compensation layer provides a second stress between 50 Mpa and 200 Mpa in a second direction opposite to the first direction, and the difference between the first stress and the second stress does not exceed 60 Mpa.