Abstract: The present invention relates to a recombinant microorganism having heterologous genes introduced thereto and a method for producing a useful material from formic acid and carbon dioxide using the microorganism. The present invention provides a novel microorganism having a cyclic metabolic pathway introduced thereto through which C3 or higher carbon organic compounds can be synthesized from formic acid and carbon dioxide, whereby carbon dioxide rich in nature and formic acid that is of low toxicity and suitable for anabolic reaction in view of reaction kinetics and which can be easily and rapidly synthesized from carbon dioxide can be used to effectively synthesize the C3 organic compound pyruvic acid from which various high-value added compound can be synthesized.

Abstract: The present disclosure relates to 7-substituted pyrrolo[2,1-f][1,2,4]triazine compounds or pharmaceutically acceptable salts thereof, and preparation methods and uses thereof. These compounds show good PI3K inhibitory activity, can effectively inhibit the activity of PI3K kinase, and has significant enhancement and improvement of pharmacokinetic properties, such as bioavailability, due to the introduction of the 7-position group; furthermore, the compounds of the present disclosure exhibit an unpredictable high selectivity and strong inhibitory activity on PI3K?, and thus these compounds can be used for treating diseases related to PI3K pathway, especially for anti-cancer or for the treatment of tumors, leukemias and autoimmune diseases. After further optimizing and screening, the compounds are expected to be developed into a new type of anti-tumor drugs.

Abstract: An apparatus and method for broadcast signal frame using a bootstrap and a preamble are disclosed. An apparatus for generating broadcast signal frame according to an embodiment of the present invention includes a time interleaver configured to generate a time-interleaved signal by performing interleaving on a BICM output signal; and a frame builder configured to generate a broadcast signal frame including a bootstrap and a preamble using the time-interleaved signal.

Abstract: A phosphate ester compound can include a cation and an anion, the anion being an alkyl phosphate. The phosphate ester compound can be a phosphate ester ionic liquid. The phosphate ester compound can be manufactured in a solvent-free environment. The phosphate ester compound can be used as an electrolyte in a battery, for example, a lithium-ion battery.

Abstract: The present disclosure is directed to novel germanosilicate compositions and methods of producing the same. In particular, this disclosure describes new silica-rich compositions of the germanosilicate designated CIT-13, with and without added metal oxides. The disclosure also describes methods of preparing and using these new germanosilicate compositions as well as the compositions themselves.

Abstract: Disclosed is a field-effect transistor and a method for manufacturing a field-effect transistor. The method comprises: forming an NMOSFET region and a PMOSFET region on a substrate; forming a hard mask on the NMOSFET region and the PMOSFET region, and patterning through the hard mask; forming a multiple of stacked nanowires in the NMOSFET region and a multiple of stacked nanowires in the PMOSFET region; forming a first array of nanowires in the NMOSFET region and a second array of nanowires in the PMOSFET region; and forming an interfacial oxide layer, a ferroelectric layer, and a stacked metal gate in sequence around each of the nanowires included in the first array and the second array. Wherein the NMOSFET region and the PMOSFET region are separated by shallow trench isolation.

Abstract: The present invention enables three-dimensional nanofabrication by isotropic shrinking of patterned hydrogels. A hydrogel is first expanded, the rate of expansion being controlled by the concentration of the crosslinker. The hydrogel is then infused with a reactive group and patterned in three dimensions using a photon beam through a limited-diffraction microscope. Functional particles or materials are then deposited on the pattern. The hydrogel is then shrunk and cleaved from the pattern.

Abstract: Provided is a three dimensional tissue scaffold comprising a stem cell attracting element associated with a matrix, and fusion protein of stem cell attracting factor and collagen-binding domain, and methods of uses thereof.

Abstract: An application of alginate sulfate in the preparation of drugs and health care products for preventing and treating diseases caused by human papillomavirus. Alginate sulfate has a strong dose-dependent inhibitory effect on HPV infection through experiments, and alginate sulfate inhibited the expression of E6 and E7 genes and proteins in HPV-transformed Hela and Caski cells in a dose-dependent manner. The alginate sulfate can be developed into a drug or a health care product against human papillomavirus by systematic scientific experiments, which will have a good market application prospect.

Abstract: An Intelligent Real-Time Robot Operating System (IRT-ROS) architecture and an operation method thereof are provided. The IRT-ROS architecture includes a General-Purpose OS kernel, a Real-Time OS kernel, and an Inter-processor Interrupt interface. The General-Purpose OS kernel is configured to run a General-Purpose OS to execute a non-real-time process. The Real-Time OS kernel is configured to run a Real-Time OS to execute a real-time process. The IPI interface is connected between the General-Purpose OS kernel and the Real-Time OS kernel, and is configured to support communication between the non-real-time process and the real-time process. The AIRT-ROS architecture allows Linux and RTERS to respectively execute non-real-time process and real-time process, and to respectively respond IRQ of non-real-time devices and IRQ of real-time devices. Communications between non-real-time process and real-time process are supported.

Abstract: Provided is a method of supporting a random access of MPEG data, the method including: obtaining at least one access unit including media data coded through processing including an encapsulation and a packetization; generating at least one media processing unit (MPU) by grouping at least one access unit; determining an initialization flag indicating whether the at least one access unit includes all of data required for initialization of a decoding process, in the at least one MPU; and inserting the initialization flag into a header of the at least one MPU.

Abstract: In some embodiments, a self-aligned electrospray device can include a silicon wafer, a fluid reservoir, and a circuit. The silicon wafer can have a layer of electrically insulating material deposited on a top surface and a deposited layer of electrically conducting material. The silicon wafer and the deposited layers can have through holes. The electrically insulating layer may be undercut. The fluid reservoir can be mounted to a bottom surface of the silicon wafer for containing fluid. The circuit can provide an electric potential difference and be coupled between the layer of electrically conducting material and the fluid reservoir.

Abstract: Bistable devices are constructed using a polynucleotide platform for the sensing of molecular events such as binding or conformational changes of target molecules. Uses include measurement of target concentration, measuring the effect of environmental condition (such as heat, light, or pH) on the target, or screening a library for molecules that bind the target or modulate its biological function. Devices comprise three regions: a top lid, bottom lid, and flexible linker or hinge between them. A device has an open configuration in which the top and bottom lid are separated, and a closed configuration they are bound close together. Binding domains or variations of the target molecule are fixed to a device so that when the molecular event occurs, the device switches from open to closed, or vice versa, which generates a signal. Devices carry DNA tags to enable separation of open and closed devices, as well as barcoding for multiplexed detection.

Abstract: The invention features methods, devices, and kits for predicting the responsiveness of a cancer patient (e.g., a breast cancer patient, such as a grade 1, 2, or 3 breast cancer patient) to anthracycline treatment by determining the expression levels of four chromosomal instability (CIN) genes including HDGF, KIAA0286, RFC4, and MSH6, collectively referred to as CIN4. Patients that have a low CIN4 score benefit from anthracycline treatment compared patients with a high CIN4 score.

Abstract: A traffic flow dynamic guiding method based on a region block includes: building communication connection with a cloud server by a vehicle-mounted terminal; performing data acquisition by the vehicle-mounted terminal, and uploading acquired data to the cloud server; receiving feedback of the cloud server by the vehicle-mounted terminal which is including an accident occurring probability of a current automobile in a set range of a current road section; sending the probability to a driver in a human-computer interaction mode; receiving communication addresses, sent by the cloud server, of the surrounding vehicle-mounted terminals in the set range by the current vehicle-mounted terminal in order to build a connection relationship with the surrounding vehicle-mounted terminals; performing running and updating after the region block relationship is built; performing traffic flow guiding on traffic accident information and performing traffic flow guiding on official vehicles by using the region block relationship.

Abstract: A ferroelectric memory is provided. The ferroelectric memory includes a substrate, a first conductive layer disposed on the substrate, a patterned oxide layer disposed on the first conductive layer and the substrate, exposing a part of the first conductive layer, a second conductive layer disposed on the exposed first conductive layer and the patterned oxide layer, an antiferroelectric layer disposed on the exposed first conductive layer and the second conductive layer, a ferroelectric layer disposed on the second conductive layer and located on the antiferroelectric layer, a conductive oxide layer disposed between the antiferroelectric layer, and a third conductive layer disposed on the conductive oxide layer and between the ferroelectric layer.

Abstract: A solid waste treatment system includes: a solid-liquid separator module configured to receive mixed solid and liquid waste and separating solid material from the mixed solid and liquid waste; an accumulator and macerator module configured to receive and macerate the solid material from the solid-liquid separator module; a drying module configured to receive and dry the macerated solid material from the accumulator and macerator module; and a combustion module configured to receive and combust the dried macerated solid material from the drying module.

Abstract: In one embodiment, a system for associating LiDAR points with objects is provided. Objects in an image are identified and bounding boxes are placed on each object in the image. LiDAR points are received and are projected into the image based on a reference frame of the image. All pixels of the image that are not inside a bounding box are changed to a color such as black. All points that are inside a bounding box are changed to a color that is unique to the particular bounding box. To determine which LiDAR points are associated with the objects in the image, for each LiDAR point a color of the pixel having the same coordinates in the image as the LiDAR point is determined. If the determined color is black than the LiDAR point is not associated with any object. Else, the LiDAR point is located in the bounding box that uses the determined color, and the LiDAR point can be labeled as being located with the object corresponding to the bounding box.

Abstract: A rock mass shear test system for high-energy accelerator computed tomography (CT) scanning includes double horizontal loading devices, a first bearing device for bearing a static shear box, a second bearing device for bearing a dynamic shear box, and a normal loading device, etc. In the test, the double horizontal loading devices simultaneously apply an identical loading force to the rock mass, and the normal loading device applies a shear force to the rock mass. The double horizontal loading devices are provided in parallel and spaced apart, a loading force is applied in the horizontal direction, and a shear force is applied in the vertical direction, so that the loading cylinder and the rock mass sample are effectively prevented from interfering with each other during the accurate scanning process of the shearing progressive failure process of the rock mass.

Abstract: Provided are an uplink transmission method and downlink transmission method in a mobile communication network including a relay. In the uplink and downlink transmission methods, frame structures and transmission timings of a backhaul downlink and a backhaul uplink are determined in consideration of at least one of a time for the relay to switch between transmission and reception and a signal transmission time. Accordingly, in a wireless communication system including a relay, it is possible to effectively perform data transmission and reception between the relay and a base station.