Abstract: The present invention provides compounds of Formula (II) (e.g., compounds of Formula (I)), and pharmaceutically compositions thereof. Compounds of Formula (II) are believed to be binders of bromodomains and/or bromodomain-containing proteins (e.g., bromo and extra terminal (BET) proteins). Also provided are methods, uses, and kits using the compounds and pharmaceutical compositions for inhibiting the activity (e.g., increased activity) of bromodomains and/or bromodomain-containing proteins and for treating and/or preventing in a subject diseases associated with bromodomains or bromodomain-containing proteins (e.g., proliferative diseases, cardiovascular diseases, viral infections, fibrotic diseases, metabolic diseases, endocrine diseases, and radiation poisoning). The compounds, pharmaceutical compositions, and kits are also useful for male contraception.
Type:
Application
Filed:
February 2, 2015
Publication date:
January 12, 2017
Applicant:
Dana-Farber Cancer Institute, Inc.
Inventors:
James E. Bradner, Nathanael S. Gray, Jun Qi, Michael R. McKeown, Dennis Buckley
Abstract: Disclosed are a method of encoding a division block in video encoding and a method of decoding a division block in video decoding. An input picture is divided into encoding unit blocks. The encoding unit blocks are divided into sub-blocks. The sub-blocks are encoded by selectively using at least one of intra prediction encoding and inter prediction encoding. A decoding process is performed through a reverse process of the encoding method. When pixel values of an encoding unit block are encoded in video encoding, the flexibility in selecting an encoding mode is increased and the efficiency of encoding is increased.
Type:
Application
Filed:
September 7, 2016
Publication date:
January 12, 2017
Applicants:
KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY, KOREAN BROADCASTING SYSTEM
Inventors:
Mun Churl KIM, Bum Shik LEE, Jae Il KIM, Chang Seob PARK, Sang Jin HAHM, In Joon CHO, Keun Sik LEE, Byung Sun KIM
Abstract: Provided is a method of synthesizing boron nitride, comprising the steps of: preparing a boron compound and a nitrogen compound; mixing the boron compound and the nitrogen compound in a non-aqueous solvent; forming an ester compound by melting the mixture in the non-aqueous solvent; dehydrating the ester compound; and forming boron nitride by nitriding the ester compound in a reductive atmosphere.
Type:
Application
Filed:
July 7, 2016
Publication date:
January 12, 2017
Applicant:
KOREA INSTITUTE OF ENERGY RESEARCH
Inventors:
In Sub HAN, Se Young KIM, Hyun Uk KIM, Young Hoon SEONG, Sang Kuk WOO, Hee Yeon KIM, Doo Won SEO, Min Soo SUH, Seong OK HAN
Abstract: A method in a data processing system and apparatus for organizing files, data items, web site members, or web pages, structured or unstructured, of multiple users stored across one or more server computers into hierarchical file structures on a recordable medium of a data processing system. A user-defined metalabel is assigned to each of the electronic files, data items, web site members, or web pages. The electronic files, data items, web site members, or web pages are organized as a function of the metalabels into the hierarchical file structures. The method includes automatically weighting of individual metalabels as a function of relevance to a corresponding one of the electronic files, data items, web site members, or web pages. Searching the plurality of hierarchical structures can then be done with a query including at least one term and a relevance threshold.
Abstract: A composition and use thereof are disclosed herein. The composition comprises at least two selected from the group of amphiphilic block copolymer, polyurethane and acidic ionic compound. Also an oil-based drilling fluid comprising the composition and a method improving shearing force of oil-based drilling fluid are disclosed. The composition disclosed herewith can raise the shearing force of oil-based drilling fluid.
Type:
Application
Filed:
July 6, 2016
Publication date:
January 12, 2017
Applicants:
China Petroleum & Chemical Corporation, SINOPEC Research Institute of Petroleum Engineering
Abstract: An electrically driven pump is provided, which includes an impeller. The impeller includes an upper plate, blades and a lower plate. The blades are formed on a lower surface of the upper plate, the blades include first blades and second blades, and a length of each of the first blades is greater than a length of each of the second blades. The first blades are uniformly distributed along a circumference of the upper plate. The first blades and the second blades are distributed alternately in the circumferential direction. The first blades each include a first head portion and a first tail portion, the second blade includes a second head portion and a second tail portion, and the first tail portion and the second tail portion are aligned with outer edge of the upper plate. The impeller arranged in such manner facilitates the improvement of hydraulic efficiency and lift.
Type:
Application
Filed:
June 28, 2016
Publication date:
January 12, 2017
Applicant:
HANGZHOU SANHUA RESEARCH INSTITUTE CO., LTD.
Abstract: An optical signal processing apparatus using a planar lightwave circuit (PLC) with a waveguide-array structure includes a PLC board including a waveguide-array structure, a cylinder lens for collimating optical signals emitted and output from the PLC board into parallel beams, a condenser lens for condensing, for each channel, optical signals output by passing through the cylinder lens, and a light receiving element for receiving optical signals condensed on at least one channel from the condenser lens and converting the optical signals into electrical signals, wherein the PLC board divides an optical signal input thereto into a plurality of different optical signals and outputs the optical signals at different propagation angles.
Type:
Application
Filed:
June 6, 2016
Publication date:
January 12, 2017
Applicant:
ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTE
Abstract: A medical imaging apparatus includes an ultrasound probe to transmit and receive an ultrasound signal to obtain an ultrasound image of an object; a sensor coupled to the ultrasound probe to provide a position information related to an ultrasound imaging position in the object; and a processor to extract a certain anatomical feature from the ultrasound image and the certain anatomical feature from a medical image of the object acquired by an imaging modality different from an ultrasound apparatus, perform a first registration between the medical image and the ultrasound image based on the certain anatomical feature, perform a second registration between the sensor and the medical image based on the position information and the first registration, and control a display to display a portion of the medical image corresponding to the ultrasound imaging position based on the second registration.
Type:
Application
Filed:
September 26, 2016
Publication date:
January 12, 2017
Applicants:
SAMSUNG MEDISON CO., LTD., KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY
Inventors:
Dong Gyu HYUN, Jong Beom RA, Duhgoon LEE, Woo Hyun NAM
Abstract: A video deblurring method based on a layered blur model includes estimating a latent image, an object motion and a mask for each layer in each frame using images consisting of a combination of layers during an exposure time of a camera when receiving a blurred video frame, applying the estimated latent image, object motion and mask for each layer in each frame to the layered blur model to generate a blurry frame, comparing the generated blurry frame and the received blurred video frame, and outputting a final latent image based on the estimated object motion and mask for each layer in each frame, when the generated blurry frame and the received blurred video frame match. Accordingly, by modeling a blurred image as an overlap of images consisting of a combination of foreground and background during exposure, more accurate deblurring results at object boundaries can be obtained.
Type:
Application
Filed:
June 23, 2016
Publication date:
January 12, 2017
Applicant:
Korea Institute of Science and Technology
Inventors:
Byeongjoo AHN, Ig Jae KIM, Junghyun CHO
Abstract: A spin modulator with phase tuning means which comprises, a spin array which consists of m×n matrix spin-transfer torque oscillators, a selection control means which selectively operates the spin-transfer torque oscillators according to an operation condition of the spin array, and a phase tuning array which includes m×n matrix phase tuning means, wherein the m×n matrix phase tuning means tune a phase synchronization operation of the spin-transfer torque oscillators according to the operation condition.
Type:
Grant
Filed:
October 15, 2013
Date of Patent:
January 10, 2017
Assignee:
Korea Advanced Institute of Science and Technology
Abstract: Disclosed decoding method of the intra prediction mode comprises the steps of: determining whether an intra prediction mode of a present prediction unit is the same as a first candidate intra prediction mode or as a second candidate intra prediction mode on the basis of 1-bit information; and determining, among said first candidate intra prediction mode and said second candidate intra prediction mode, which candidate intra prediction mode is the same as the intra prediction mode of said present prediction unit on the basis of additional 1-bit information, if the intra prediction mode of the present prediction unit is the same as at least either the first candidate intra prediction mode or the second candidate intra prediction mode, and decoding the intra prediction mode of the present prediction unit.
Type:
Grant
Filed:
October 4, 2011
Date of Patent:
January 10, 2017
Assignees:
Electronics and Telecommunications Research Institute, Korea Advanced Institute of Science and Technology
Inventors:
Jong Ho Kim, Hui Yong Kim, Se Yoon Jeong, Sung Chang Lim, Ha Hyun Lee, Jin Ho Lee, Suk Hee Cho, Jin Soo Choi, Jin Woong Kim, Chie Teuk Ahn, Mun Churl Kim, Bum Shik Lee
Abstract: At least two types of dielectric materials such as oxide nanosheets having a layered perovskite structure that differ from each other are laminated, and the nanosheets are bonded to each other via an ionic material, thereby producing a superlattice structure-having ferroelectric thin film. Having the layered structure, the film can exhibit ferroelectricity as a whole, though not using a ferroelectric material therein. Accordingly, there is provided a ferroelectric film based on a novel principle, which is favorable for ferroelectric memories and others and which is free from a size effect even though extremely thinned.
Type:
Grant
Filed:
October 4, 2011
Date of Patent:
January 10, 2017
Assignee:
NATIONAL INSTITUTE FOR MATERIALS SCIENCE
Abstract: The present invention relates to an improved method for purifying a sulfonated aromatic monomer. The method is an economical method capable of providing a highly pure sulfonated aromatic monomer, in which a salt precipitation step and a recrystallization step are simplified while maintaining the reaction conditions used in a conventional method for synthesizing the sulfonated aromatic monomer, and a purification process is carried out using an easily available and stable chemical substance. The sulfonated aromatic monomer obtained by the purification method will be useful for the preparation of a polymer for a polymer electrolyte membrane and will be advantageous to synthesize polymer with high molecular weight.
Type:
Grant
Filed:
November 14, 2011
Date of Patent:
January 10, 2017
Assignee:
KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY
Inventors:
Young Taik Hong, Seog Je Kim, Ji Young Park, Dong Hyun Lee
Abstract: The combination multi-effect distillation and multi-stage flash evaporation system integrates a multi-stage flash (MSF) evaporation system with a multi-effect distillation (MED) system such that the flashing temperature range of the MSF process is shifted upward on the temperature scale, while the MED distillation process operates in the lower temperature range. The multi-stage flash evaporation system includes a plurality of flash evaporation/condensation stages, such that the multi-stage flash evaporation system receives a volume of seawater or brine from an external source and produces distilled water. The multi-effect distillation system includes a plurality of condensation/evaporation effects, such that the multi-effect distillation system receives concentrated brine from the multi-stage flash desalination system and produces distilled water.
Type:
Grant
Filed:
December 9, 2015
Date of Patent:
January 10, 2017
Assignee:
Kuwait Institute for Scientific Research
Abstract: A method for synthesizing nanodiamonds includes high energy ball milling of graphite powder for a period of at least 52 hours at a rotation speed of about 400 rotations per minute to produce nanodiamonds. The ball milling can occur in an inert atmosphere at ambient pressure and room temperature. The nanodiamonds can have a spherical morphology and a particle size distribution ranging from about 1 nanometer to about 10 nanometers.
Type:
Grant
Filed:
February 29, 2016
Date of Patent:
January 10, 2017
Assignee:
KUWAIT INSTITUTE FOR SCIENTIFIC RESEARCH
Abstract: A composite powder is provided. The composite powder comprises 80-97 wt % of carbide and 3-20 wt % of blending metal powder comprising cobalt and a first metal powder, wherein the first metal powder is formed of one of aluminum, titanium, iron, nickel, or a combination thereof, and the amount of cobalt is 90-99% of total blending metal powder.
Type:
Grant
Filed:
January 8, 2015
Date of Patent:
January 10, 2017
Assignee:
INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE
Abstract: Provided is a method of manufacturing an anode core-shell complex for a solid oxide fuel cell, including (A) manufacturing a stabilized zirconia (YSZ) sol by using zirconium hydroxide (Zr(OH)4) and yttrium nitrate (Y(NO3)3.6H2O) as a starting material and distilled water as a solvent by a hydrothermal method, (B) agitating nickel chloride, stabilized zirconia in a sol state, and a surfactant, (C) adding sodium hydroxide (NaOH), (D) adjusting a pH to a range of 6 to 8, and (E) sintering the nickel-stabilized zirconia core-shell powder.
Type:
Grant
Filed:
November 25, 2013
Date of Patent:
January 10, 2017
Assignee:
KOREA INSTITUTE OF CERAMIC ENGINEERING AND TECHNOLOGY
Inventors:
Byung Hyun Choi, Mi Jung Ji, Min Jin Lee, Sun Ki Hong, Young Jin Kang
Abstract: Methods and apparatus for monitoring wideband GHz spectrum for wireless communication, and sensing and decoding respective frequency components of a time-varying signal corresponding to the monitored spectrum. Concepts relating to sparse Fast Fourier Transform (sFFT) techniques facilitate identification of one or more frequency components of a sparsely occupied spectrum by sub-sampling the signal corresponding to the monitored spectrum at a sampling rate below the Nyquist criterion. The disclosed methods and apparatus may be implemented using conventional relatively low-power wireless receivers and using off-the-shelf relatively inexpensive low-speed and low-power analog-to-digital converters (ADCs) typically employed in WiFi devices or cellular phones, in tandem with unique processing techniques based on sFFTs and sub-Nyquist criterion sampling, and have demonstrated efficacy even in scenarios where the monitored spectrum is not sparse.
Type:
Grant
Filed:
November 19, 2014
Date of Patent:
January 10, 2017
Assignee:
MASSACHUSETTS INSTITUTE OF TECHNOLOGY
Inventors:
Dina Katabi, Haitham Z. Al-Hassanieh, Lixin Shi, Omid Salehi-Abari, Ezzeldin Hamed
Abstract: A weak magnetic force magnetic separator, including: a belt conveyor conveying separation target particles; and a suspended magnet unit provided at a distance above the belt conveyor and configured to magnetically attract, with a uniform, weak magnetic force, the separation target particles conveyed over a belt. With a length of the magnet unit in its longer direction being greater than a belt width of the belt, and with the magnet unit placed such that its longer direction is aligned with the belt width direction and its both ends overhang the belt width, and such that a distance from the surface of the belt is constant across its longer direction, magnetic flux density variations in the belt width direction over the belt surface facing the magnet unit are 10% or less within a weak magnetic force range of from over 0 to 700 gauss.
Type:
Grant
Filed:
February 7, 2013
Date of Patent:
January 10, 2017
Assignee:
NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY