Patents Assigned to INSTITUTE
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Patent number: 11406785Abstract: An aspect of the present invention is a gas product including: a gas container; and a gas composition filled in the gas container, in which the gas composition includes nitrogen monoxide, hydrogen, and an inert gas, and a concentration of the nitrogen monoxide is 20% by volume or less based on a volume of the gas composition.Type: GrantFiled: March 4, 2020Date of Patent: August 9, 2022Assignees: SUMITOMO SEIKA CHEMICALS CO., LTD., THE KITASATO INSTITUTEInventors: Masaaki Yamada, Ichiro Misawa, Hirosuke Kobayashi, Kenichi Kokubo
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Patent number: 11410685Abstract: Disclosed are a method for detecting speech concatenating points and a storage medium. The method includes: acquiring a speech to be detected, and determining high-frequency components and low-frequency components of the speech to be detected; extracting first cepstrum features and second cepstrum features corresponding to the speech to be detected according to the high-frequency components and the low-frequency components; splicing the first and the second cepstrum feature of speech per frame in the speech to be detected in units of frame so as to obtain a parameter sequence; inputting the parameter sequence into a neural network model so as to obtain a feature sequence corresponding to the speech to be detected, wherein the model has been trained, has learned and stored a correspondence between the parameter sequence and the feature sequence; and performing detection of speech concatenating points on the speech to be detected according to the feature sequence.Type: GrantFiled: February 9, 2022Date of Patent: August 9, 2022Assignee: INSTITUTE OF AUTOMATION, CHINESE ACADEMY OF SCIENCESInventors: Jianhua Tao, Ruibo Fu, Jiangyan Yi
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Patent number: 11407659Abstract: A desalination and cooling system includes a single effect water-lithium bromide vapor absorption cycle (VAC) system and a forward osmosis with thermal-recovery (FO-TR) desalination system. The FO system employs a Thermo-Responsive Draw Solution (TRDS) Fresh water flows from the FS to the TRDS without application of pressure on the saline water. Afterwards, only thermal energy is required to extract fresh water from the TRDS and recover or regenerate the draw solution. The VAC system serves as a cooling source for cooling or air conditioning applications, generating waste heat as a result. The waste heat generated by the VAC system provides the thermal energy needed to recover the draw solution (DS). The VAC system can be powered by low-grade heat sources like solar thermal energy.Type: GrantFiled: July 9, 2021Date of Patent: August 9, 2022Assignee: KUWAIT INSTITUTE FOR SCIENTIFIC RESEARCHInventors: Hassan Kamal Mohamed Abdulrahim, Mansour Ahmed
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Patent number: 11406653Abstract: The present invention relates to the use of mannuronic diacid oligosaccharide composition in the treatment of pain.Type: GrantFiled: June 28, 2019Date of Patent: August 9, 2022Assignees: GREEN VALLEY (SHANGHAI) PHARMACEUTICALS CO., LTD., SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCESInventors: Meiyu Geng, Xianliang Xin, Zhenqing Zhang, Jian Ding
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Patent number: 11408838Abstract: A method for a multielement analysis via neutron activation. The method includes generating fast neutrons with an energy in the range of 10 keV to 20 MeV and moderating the neutrons, irradiating the sample with the neutrons, and measuring the gamma radiation emitted by the irradiated sample using a detector to determine at least one element of the sample. The sample continuously irradiated in a non-pulsed fashion. The measurement is implemented during the irradiation. The determination of the at least one element includes an evaluation of the measured gamma radiation. The sample is subdivided into individual partitions and the measurement is implemented using a collimator. The evaluation includes a spatially resolved and energy-resolved determination of the neutron flux within the respective partition of the sample and calculation of energy-dependent photopeak efficiencies and neutron flux and neutron spectrum within a single partition of the sample by an approximation method.Type: GrantFiled: May 28, 2018Date of Patent: August 9, 2022Assignees: AACHEN INSTITUTE FOR NUCLEAR TRAINING GMBH, FRAMATOME GMBHInventors: Kai Krycki, John Kettler, Andreas Havenith
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Patent number: 11407985Abstract: The invention provides for delivery, engineering and optimization of systems, methods, and compositions for manipulation of sequences and/or activities of target sequences. Provided are delivery systems and tissues or organ which are targeted as sites for delivery. Also provided are vectors and vector systems some of which encode one or more components of a CRISPR complex, as well as methods for the design and use of such vectors. Also provided are methods of directing CRISPR complex formation in eukaryotic cells to ensure enhanced specificity for target recognition and avoidance of toxicity and to edit or modify a target site in a genomic locus of interest to alter or improve the status of a disease or a condition.Type: GrantFiled: June 10, 2016Date of Patent: August 9, 2022Assignees: THE BROAD INSTITUTE, INC., MASSACHUSETTS INSTITUTE OF TECHNOLOGYInventors: Le Cong, David Benjamin Turitz Cox, Matthias Heidenreich, Randall Jeffrey Platt, Lukasz Swiech, Feng Zhang
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Patent number: 11406588Abstract: Disclosed is a method for eliminating odors including administering a deodorant composition containing an Opuntia ficus (prickly pear) extract or a fraction thereof as an active ingredient. The deodorant composition, which further contains a persimmon extract or a fraction thereof, a persimmon juice, or a green tea extract or a fraction thereof, is useful as a deodorizer for removing or reducing ammonia and trimethylamine.Type: GrantFiled: November 13, 2020Date of Patent: August 9, 2022Assignee: THE WELLNESS LIFE INSTITUTE CO., LTD.Inventors: Hyun Joo Lee, Ha Young Choi, Na Young Choi, Ha Young Song
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Patent number: 11406659Abstract: The present invention relates to the use of mannuronic diacid oligosaccharide composition in the treatment of inflammation.Type: GrantFiled: June 28, 2019Date of Patent: August 9, 2022Assignees: GREEN VALLEY (SHANGHAI) PHARMACEUTICALS CO., LTD., SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCESInventors: Meiyu Geng, Xianliang Xin, Zhenqing Zhang, Jian Ding
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Patent number: 11406064Abstract: The invention discloses a method of rapid generation-adding breeding of rice in the technical field of rice breeding, including soaking seeds of the rice, germination, seedlings cultivation, managing and regulating of the rice at the growth stage, and harvesting the rice. The managing and regulating the rice at the growth stage includes dynamic light quality and photoperiod control in vegetative growth period, heading period and pustulation period; growth period involves light environment regulation with the ratio of red light:blue light:white light of 0.8-1:0.8-1:1.0, photoperiod of 16-18 h; heading period involves light environment regulation with the ratio of red light:blue light:white light of 1-2:0.5-1:1, photoperiod of 12-13.5 h; and pustulation period includes light environment regulation with the ratio of red light:blue light:white light of 1-2:1:1, photoperiod of 16-18 h.Type: GrantFiled: January 24, 2022Date of Patent: August 9, 2022Assignee: INSTITUTE OF URBAN AGRICULTURE, CHINESE ACADEMY OF AGRICULTURAL SCIENCESInventors: Qichang Yang, Zhonghua Bian, Zonggeng Li, Sen Wang, Wei Lu, Chengbo Zhou
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Patent number: 11410746Abstract: Methods for the top-down design of nucleic acid nanostructures of arbitrary geometry based on target shape of spherical or non-spherical topology are described. The methods facilitate 3D molecular programming of lipids, proteins, sugars, and RNAs based on a DNA scaffold of arbitrary 2D or 3D shape. Geometric objects are rendered as node-edge networks of parallel nucleic acid duplexes, and a nucleic acid scaffold routed throughout the network using a spanning tree formula. Nucleic acid nanostructures produced according to top-down design methods are also described. In some embodiments, the nanostructures include single-stranded nucleic acid scaffold, DX crossovers, and staple strands. In other embodiments, the nanostructures include single-stranded nucleic acid scaffold, PX crossovers and no staples. Modified nanostructures include chemically modified nucleotides and conjugated to other molecules are described.Type: GrantFiled: April 27, 2017Date of Patent: August 9, 2022Assignee: MASSACHUSETTS INSTITUTE OF TECHNOLOGYInventors: Remi Veneziano, Sakul Ratanalert, Tyson Shepherd, Hyungmin Jun, Mark Bathe
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Patent number: 11406322Abstract: Methods and systems for measuring muscle sarcomere length are disclosed. In an embodiment, a method comprises illuminating a set of muscle fibers with electromagnetic radiation, measuring an intensity of the electromagnetic radiation as reflected from the muscle fibers, the measuring occurring as a function of wavelength, determining wavelengths corresponding to maximums of reflected intensity, and correlating the determined wavelengths with respective muscle sarcomere lengths. In an embodiment, a system comprises an illumination source system for illuminating the set of muscle fibers with electromagnetic radiation, and an analyzer for measuring the intensity of the electromagnetic radiation as reflected from the muscle fibers.Type: GrantFiled: September 27, 2019Date of Patent: August 9, 2022Assignee: REHABILITATION INSTITUTE OF CHICAGOInventors: Richard L. Lieber, Stojan Radic, Kevin Young
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Patent number: 11409746Abstract: A method of processing database queries according to an embodiment of the disclosure includes the steps of acquiring an input query of a database, generating a join graph consisting of vertexes corresponding to the tables of the database and edges corresponding to join information among the tables, dividing the join graph into a plurality of subgraphs, and for the input query, generating an execution plan of a target query including N-ary join operators by using the plurality of subgraphs, optimizing the execution plan of the target query based on a cost model, acquiring a table sort algorithm of the N-ary join operators included in the target query based on an available size of a GPU or CPU memory, determining a sort order of one or more join columns included in the tables of the N-ary join operators, and based on the sort order of the one or more join columns, performing an operation for the plurality of subgraphs.Type: GrantFiled: November 10, 2020Date of Patent: August 9, 2022Assignee: DAEGU GYEONGBUK INSTITUTE OF SCIENCE AND TECHNOLOGYInventors: Min-Soo Kim, Yoon Min Nam, Sung Jin Lee
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Patent number: 11412507Abstract: A transmission and reception method of a radio signal by a terminal in a wireless communication system comprises the steps of: determining whether or not transmission of an uplink radio signal or reception of a downlink radio signal allocated to a terminal is possible on a slot configured to comprise at least one of one or more downlink symbols for downlink transmission, one or more flexible symbols and one or more uplink symbols for uplink transmission; and controlling the transmission of the uplink radio signal or the reception of the downlink radio signal on the basis of the determination.Type: GrantFiled: March 10, 2020Date of Patent: August 9, 2022Assignee: WILUS INSTITUTE OF STANDARDS AND TECHNOLOGY INC.Inventors: Kyungjun Choi, Minseok Noh, Jinsam Kwak
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Patent number: 11406604Abstract: A method for manufacturing supported lipid bilayer on a porous silica nanoparticle with a ?-potential comprised between ?10 mV and +10 mV, the method comprising the steps of (a) providing a negatively charged supported lipid bilayer on a porous silica nanoparticle, wherein the negatively charged supported lipid bilayer has a ?-potential inferior to ?15 mV and wherein the negatively charged supported lipid bilayer comprised at least one phospholipid and; (b) adding a formulation of lipids, the lipids being 1,2-dioleoyl-3-trimethylammonium-propane alias DOTAP, cholesterol and at least one lipid different from DOTAP and cholesterol. The method further comprises the step of (c) performing an ultra-sonication for promoting DOTAP incorporation. The method can be supplemented by the step of addition of alginate and the step of cross-linking the alginate. Also a nanocapsule and composition comprising the nanocapsule.Type: GrantFiled: January 17, 2018Date of Patent: August 9, 2022Assignee: LUXEMBOURG INSTITUTE OF SCIENCE AND TECHNOLOGY (LIST)Inventors: Gaelle Corne, Jean-Sebastien Thomann
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Patent number: 11409966Abstract: An apparatus to: analyze a data set to identify a candidate topic not in a set of topics; determine whether the prominence of the candidate topic within the data set meets a threshold; in response to meeting the threshold, retrieve a rate of increase in frequency of the candidate topic in online searches; in response to meeting a threshold rate of increase, retrieve the keyword most frequently used in online searches for the candidate topic, use the keyword to retrieve a supplemental data set, and analyze input data extracted from the supplemental data set to determine whether the candidate topic can change the accuracy of a forecast model; and in response to determining that the candidate topic can change the accuracy, add the candidate topic to the set of topics and replace the forecast model with a forecast model trained for the set of topics augmented with the candidate topic.Type: GrantFiled: December 17, 2021Date of Patent: August 9, 2022Assignee: SAS INSTITUTE INC.Inventors: Anand Arun Phand, Sudeshna Guhaneogi, Narender Ceechamangalam Veeraraghavan, Ravinder Singh Chauhan, Shikha Bhat, Kaustubh Yashvant Khandwe, Shalini Sinha, Vineet Roy, Alina Olegovna Asadullina, Vitaly Igorevich Plekhanov, Elizaveta Alekseevna Lavrenova, Dmitry Sergeevich Bodunov, Assol Raufjonovna Kubaeva, Stephen Joseph Ondrik, Steffen-Horst Schlüter, Joseph Michael Martino, John Zhiqiang Zhao, Pravinkumar Bhalerao, Valentina Larina
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Patent number: 11407745Abstract: Disclosed are a compound selected from novel indazole derivatives, pharmaceutically acceptable salts thereof, hydrates thereof and stereoisomers thereof, a method for preparing the compound, and a pharmaceutical composition for preventing, alleviating or treating cancer containing the compound as an active ingredient. The novel indazole derivatives exhibit excellent ABL/DDR1 inhibitory efficacy and anti-proliferative efficacy against cancer cells, specifically blood cancer cells, and inhibitory activity against ABL T315I point mutations, thus being useful for the prevention, alleviation or treatment of cancer, specifically blood cancer, especially chronic myelogenous leukemia.Type: GrantFiled: June 10, 2020Date of Patent: August 9, 2022Assignee: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGYInventors: Gyo Chang Keum, Ashraf Kareem El-Damasy, Hee Won Jin, Taek Kang, Eun Kyoung Bang
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Patent number: 11410546Abstract: Systems and methods determining velocity of an object associated with a three-dimensional (3D) scene may include: a LIDAR system generating two sets of 3D point cloud data of the scene from two consecutive point cloud sweeps; a pillar feature network encoding data of the point cloud data to extract two-dimensional (2D) bird's-eye-view embeddings for each of the point cloud data sets in the form of pseudo images, wherein the 2D bird's-eye-view embeddings for a first of the two point cloud data sets comprises pillar features for the first point cloud data set and the 2D bird's-eye-view embeddings for a second of the two point cloud data sets comprises pillar features for the second point cloud data set; and a feature pyramid network encoding the pillar features and performing a 2D optical flow estimation to estimate the velocity of the object.Type: GrantFiled: May 18, 2020Date of Patent: August 9, 2022Assignee: TOYOTA RESEARCH INSTITUTE, INC.Inventors: Kuan-Hui Lee, Matthew T. Kliemann, Adrien David Gaidon
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Patent number: 11407941Abstract: The present disclosure provides a fluorescent nanomaterial and a preparation method and applications thereof, and the preparation method comprises: subjecting amphiphilic molecules in a solvent system to an illumination treatment and/or a heat treatment to obtain fluorescent nanomaterials. The preparation of fluorescent nanomaterials provided by the present disclosure is simple in process, simple and easily available in raw materials and requires neither additional addition of a strong acid, a strong alkali, a passivating agent and the like, nor high temperature and high pressure in the preparation process. The whole process is environmentally friendly and pollution-free and the products can be used in various fields.Type: GrantFiled: March 22, 2019Date of Patent: August 9, 2022Assignee: INSTITUTE OF PROCESS ENGINEERING, CHINESE ACADEMY OF SCIENCESInventors: Hongbin Cao, He Zhao, Qin Dai
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Publication number: 20220243186Abstract: Provided are a fusion protein used in a CRISPR/Cas system, and a complex including the same and use thereof. Since the gene editing complex including the fusion protein of the present disclosure includes an NKG2D ligand capable of binding to NKG2D expressed on the membrane of natural killer cells, it may be specifically delivered to NKG2D receptor-expressing cells or natural killer cells. Since it may be effectively delivered into the cells through endocytosis of NKG2D without a carrier, a target gene or a target DNA of NKG2D receptor-expressing cells or natural killer cells may be manipulated using the complex.Type: ApplicationFiled: December 7, 2021Publication date: August 4, 2022Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGYInventors: Mihue JANG, Junghee KIM, Sang Chul SHIN, Young Eun LEE, Han-Na YOON
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Publication number: 20220242390Abstract: An energy management method for a hybrid electric vehicle (HEV) includes: acquiring a state variable of an HEV; determining a speed of the HEV at a next moment by using a Markov model; according to a speed at a current moment and an acceleration at the current moment so that determining required power of the HEV at the next moment; determining battery power of the HEV according to the required power of the HEV at the next moment and engine power so that constructing a dynamic model for battery charging/discharging; determining energy costs of the HEV according to the required power at the next moment; constructing an energy optimization scheduling model of the HEV according to the energy costs; and determining an energy management model of the HEV according to the energy optimization scheduling model and the dynamic model for battery charging/discharging, to precisely manage energy of the HEV.Type: ApplicationFiled: July 7, 2020Publication date: August 4, 2022Applicant: SHANDONG INSTITUTE OF ADVANCED TECHNOLOGY, CHINESE ACADEMY OF SCIENCES CO., LTDInventors: Weimin LI, Haibin WANG, Lijuan LI, Jingjing ZHANG