Abstract: A magnetic random access memory having reference magnetic resistance is provided. The memory includes at least one magnetic memory cell having an antiferromagnet layer, a pinned layer formed thereon, a tunnel barrier layer formed thereon, and a free layer formed thereon. The pinned layer and free layer are arranged orthogonally to form a reference magnetic resistance state. Through the provided MRAM structure, the access accuracy is greatly increased and the access speed is accelerated.

Abstract: An adjusting technology of thermal processing is provided. A heating lamp and a reflector are disposed over a wafer and the heat flux distribution on the wafer generated by the individual heating lamp is measured and adjusted. A set of heating lamps formed by heating lamps is disposed over the wafer. The heating lamps are in concentric rings and arranged as an axi-symmetric array. The relative position between the set of heating lamps and the wafer is adjusted so that the wafer center is at the position with local mean heat flux from lamps between the most inner lamp subset and its adjacent lamp subset. Followed by adjusting the heating powers, either or both of the wafer and the set of heating lamps are rotated respect to the center of the wafer, so as to improve uniformity of the heat flux distribution on the heated object.

Abstract: The present invention provides a method for reducing stroke-related tissue damage by treating a mammal with E-selectin. Preferably, this treatment induces E-selectin tolerance in the mammal. Another aspect of the invention is a method for inducing E-selectin tolerance in a mammal through intranasal administration of E-selectin, preferably including booster administrations. The present methods are especially adapted for use in patients at increased risk of stroke or who may become at increased risk of stroke.

Abstract: This invention is a method of forming a nitride layer on at least one metal or metal alloy biomedical device, comprising: providing a vacuum chamber with at least one biomedical device positioned thereon on a worktable within the vacuum chamber; reducing the pressure in the vacuum chamber; introducing nitrogen into the vacuum chamber so that the pressure in the vacuum chamber is about 0.01 to about 10 milli-Torr; generating electrons within the vacuum chamber to form positively charged nitrogen ions; providing a negative bias to the worktable so that the positively charged nitrogen ions contact the biomedical devices under conditions such that a nitride layer forms on the at least one prosthetic device.

Abstract: An electrohydrodynamic conduction liquid pumping system includes a vessel configured to contain a liquid or a liquid/vapor therein. This vessel can be of a elongate conduit configuration, an elongate channel configuration or a liquid enclosure configuration. At least a single pair of electrodes are disposed in a spaced apart relation to each other on the vessel and configured to be oriented in the liquid. A power supply is coupled to the electrodes and operable to generate electric fields in between the pair of electrodes, the electric forces inducing a net liquid movement relative to the vessel. Various electrode designs are embraced within the concept of this invention.

Abstract: A gemstone fluorescence measuring device according to the invention generally includes an ultraviolet (“UV”) emission chamber, a UV radiation source, and a light meter assembly. The UV radiation source includes an upper light emitting diode (“LED”) and a lower LED that radiate a gemstone under test from both above and below the gemstone. The UV radiation source provides both trans-radiation and direct radiation to the gemstone, and the UV radiation source has an adjustable intensity, thus facilitating calibration of the fluorescence measuring device. The light meter assembly includes a light detector that detects the visible light emitted from the gemstone under test in response to the UV radiation. The light detector is configured to simulate the spectral characteristics of the human eye. The fluorescence measuring device converts the measured visible light into a numerical lux reading, which can then be converted into a fluorescence grade for the gemstone under test.

Abstract: A region-based illumination-normalization method and system utilizes a plurality of filters to filter a test image for obtaining a high frequency image and a low pass image. The low pass image is segmented into several regions by an image segmentation unit so that a region-based adjustment unit normalizes the regions based on an illumination reference model, respectively. Finally, an image combination unit is employed to combine the high frequency image and the low pass image that is normalized.

Abstract: Method for inoculating a vertebrate host against malaria, by administering to the host a live Plasmodium organism that is genetically engineered to disrupt a liver-stage-specific gene function.

Abstract: Probes, and systems and methods for optically scanning a conical volume in front of a probe, for use with an imaging modality, such as Optical Coherence Tomography (OCT). A probe includes an optical fiber having a proximal end and a distal end and defining an axis, with the proximal end of the optical fiber being proximate a light source, and the distal end having a first angled surface. A refractive lens element is positioned proximate the distal end of the optical fiber. The lens element and the fiber end are both configured to separately rotate about the axis so as to image a conical scan volume when light is provided by the source. Reflected light from a sample under investigation is collected by the fiber and analyzed by an imaging system. Such probes may be very compact, e.g., having a diameter 1 mm or less, and are advantageous for use in minimally invasive surgical procedures.

Abstract: The present invention relates to hemostatic materials made of water-soluble cellulose ether derivatives, such as methylcellulose, ethylcellulose, hydroxyethylcellulose, and pharmaceutically acceptable salts of carboxymethylcellulose, especially to hemostatic materials made of water-soluble cellulose ether derivatives capable of being absorbed in live body. The present invention also relates to the use of water-soluble cellulose hemostatic materials for the preparation of internal and external hemostatic articles and pharmaceutical compositions, and hemostatic articles and pharmaceutical compositions thereof.

Abstract: Methods for making glycoproteins, both in vitro and in vivo, are provided. One method involves incorporating an unnatural amino acid into a protein and attaching one or more saccharide moieties to the unnatural amino acid. Another method involves incorporating an unnatural amino acid that includes a saccharide moiety into a protein. Proteins made by both methods can be further modified with additional sugars.

Abstract: The present invention provides a sensor and methods for determining kinase activity.

Abstract: Intake air is severely restricted during cold start of a diesel engine to provide high engine-out exhaust gas temperatures and quickly heat exhaust treatment devices. Cylinder pressures are maintained substantially below the pressure of the ambient atmosphere during a principal portion of the intake stroke of each combustion cycle to promote rapid fuel vaporization and higher combustion temperatures. The engine is operated in a premixed charge compression ignition combustion mode to provide a high engine-out exhaust temperature, stable combustion, and low emissions during the cold start period.

Abstract: The present invention relates to a nucleic acid molecule comprising the HpYPS1 gene encoding H. polymorpha yapsin1, a polypeptide encoded by the nucleic acid molecule, a H. polymorpha mutant strain having reduced yapsin activity by mutation of the HpYPS gene encoding H. polymorpha yapsin1, a recombinant H. polymorpha strain expressing a foreign protein produced by introducing a gene encoding the foreign protein into the H. polymorpha mutant strain, and a process for preparing a foreign protein comprising culturing the recombinant H. polymorpha strain under conditions to express the foreign protein and isolating the foreign protein from the culture.

Abstract: A multiple source array including a guided-wave structure having a dielectric core and a cladding covering the dielectric core; and an array of dielectric-filled, guided-wave cavities in the cladding extending transversely from the dielectric core and forming an array of apertures through which optical energy that is introduced into the core exits from the core.

Abstract: The invention provides monoclonal antibodies and other binding agents to human cytochrome P450 2C19 having advantageous properties, including capacity substantially to inhibit enzyme activity of human cytochrome P450 2C19 and lack of specific binding to other human cytochrome P450s. The binding agents of the invention are useful inter alia in methods for screening drugs for metabolism by cytochrome P450 2C19, and in methods of measuring P450 2C19 levels in individuals relative to P450 2C19 levels in a control population.

Abstract: This invention relates to the diagnosis and monitoring of ischemia, including but not limited to myocardial and cerebral ischemia, by measuring the concentration of molecules that do not originate from the ischemic tissue but whose concentration in the blood and other fluids changes as a consequence of the ischemic state.

Abstract: An on-chip inductor device for Integrated Circuits utilizes coils on a plurality of metal layers of the IC with electrical connectors between the coils and a magnetic core for the inductor of stacked vias running between the coils. The magnetic core is made from a series of stacked vias which are deposited between each metal layer of the IC having a coil. The magnetic core desirably includes an array of magnetic bars comprising the magnetic core. The via material of the magnetic core may be both magnetic and electrically conductive. The magnetic and electrically conductive via material may also be used for the planar coil electrical connectors or other electrically conductive parts of the IC, or both, thereby lessening fabrication steps. Films of magnetic material may be formed at the ends of the inductor to provide a closed magnetic circuit for the inductor. A high Q factor inductor of small (e.g., transistor) size is thus obtained.

Abstract: Rectangular protruding parts 2 are formed on the surface of one side of a quartz crystal substrate 1; these protruding parts 2 are formed as aggregates of rectangular protruding parts 4 of an even finer pattern. Recessed parts 5 which are lower than the surfaces of the protruding parts 4 are formed between the protruding parts 4; however, the width of these recessed parts 5 is narrow, so that when the protruding parts 4 are viewed on the macroscopic scale, numerous protruding parts 4 are aggregated, and appear to form single protruding parts 2. Such a quartz crystal substrate 1 is clamped between heater blocks from above and below, and the temperature of the quartz crystal substrate is elevated. At the point in time at which this temperature reaches a desired temperature, the substrate 1 is pressed by means of a press. Consequently, stress acts only on the portions corresponding to the protruding parts 4, so that the crystal axis components are inverted only in these portions.

Abstract: A vector system that will produce a pseudotyped lentiviral vector that can be used to deliver a desired gene is disclosed. The vector constructs that are described include a number of modifications that enhance the safety of the vector. The vector can be used to more specifically target cells for expression of certain genes.