Abstract: A method for self-supervised depth and ego-motion estimation is described. The method includes determining a multi-camera photometric loss associated with a multi-camera rig of an ego vehicle. The method also includes generating a self-occlusion mask by manually segmenting self-occluded areas of images captured by the multi-camera rig of the ego vehicle. The method further includes multiplying the multi-camera photometric loss with the self-occlusion mask to form a self-occlusion masked photometric loss. The method also includes training a depth estimation model and an ego-motion estimation model according to the self-occlusion masked photometric loss. The method further includes predicting a 360° point cloud of a scene surrounding the ego vehicle according to the depth estimation model and the ego-motion estimation model.

Abstract: An artificial gene has a 15N abundance exceeding a natural abundance in bases of at least a portion of DNA. A method for mutating a gene includes a first step of producing a state in which 15N is unevenly distributed into a prescribed DNA in a living cell; and a second step of irradiation with a proton beam at an energy at which the 15N produces a resonant nuclear reaction.

Abstract: Disclosed herein is a method for compressing an image for machine vision, the method including detecting objects in an input image using an object detection network, generating a foreground image including bounding boxes corresponding to the objects and a background image, which is an image acquired by excluding the bounding boxes from the input image, encoding the foreground image and the background image, and decoding the encoded foreground image and the encoded background image.

Abstract: Systems and methods for targeted gene modification, targeted insertion, perturbation of gene transcripts, and nucleic acid editing. Novel nucleic acid targeting systems comprise components of Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) systems and transposable elements.

Abstract: The present disclosure relates to an assay for determining drug-target engagement in real-time. Specifically, the present disclosure provides a method for determining drug candidate-target interaction in real-time in living systems using Activity-based Reporter Gene Technology-Bioluminescence Resonance Energy Transfer (AbRGT-BRET) based assay. The said assay is useful for High Throughput Screening of compounds to a specific target.

Abstract: A magnetic-field measuring apparatus includes a SQUID; and flux-locked loop circuitry including first circuitry that includes an amplifier connected to an output of the SQUID, and second circuitry connected to the first circuitry. The first circuitry is along an inner surface or an outer surface of a shielding material that separates an inside of a magnetically shielded room from an outside of the magnetically shielded room, the magnetically shielded room including the SQUID. The second circuitry is in the outside of the magnetically shielded room.

Abstract: A through substrate via structure and a manufacturing method thereof, and a redistribution layer structure and a manufacturing method thereof are provided. The through substrate via structure includes a columnar conductive layer and a nanotwinned metal film disposed at least around the conductive layer. In a cross-section of the through substrate via structure, relative to a total area of the conductive layer and the nanotwinned metal film, an area ratio of the nanotwinned metal film is 50% or less by area.

Abstract: An apparatus for memory integrated management in a cluster system including a plurality of physical nodes connected to each other by a network determines one of the plurality of physical nodes as a node to place a new virtual machine, allocates the first type of memory allocated to the one physical node to the new virtual machine as much as the memory capacity required by the new virtual machine, and distributes the second type of memory to a plurality of virtual machines running on the plurality of physical nodes by integrating and managing the second type of memory allocated to each of the plurality of physical nodes. In this case, the access speed of the second type of memory is faster than that of the first type of memory.

Abstract: A divisible device and a method for sand production and sand control experiment for natural gas hydrate exploitation. The experimental device includes a reactor system, a feeding system, a separation and measurement system, a water-bath jacket system, a support and safety system, and a software recording and analyzing system. In the reactor system, the reactor units can be combined in different ways depending on the experimental conditions and purposes. The reactor units include: left/right reactor units, secondary reactor units, central reactor units, and caps. The combination of a left/right reactor unit with a cap gives a hydrate formation reactor without sand control screens. Combining the left/right reactor unit, secondary left/right reactor units and central reactor units with other accessories allows the reactor system to carry out the simulation experiments with either zero, one, or two view zones, and with either one or two wells.

Abstract: The present disclosure provides compositions (e.g., pyrimidines) and methods capable of potentiating the effects of antimicrobial agents and/or antiviral agents against bacterial infections and/or viral infections, respectively. Methods of sensitizing bacteria to antimicrobial agents and/or antiviral agents, as well as pharmaceutical compositions and therapeutic/prophylactic methods directed at microbial infections and/or viral infections are also provided.

Abstract: A method of forming dialkyl carbonate is provided, which includes introducing carbon dioxide into a catalyst to form dialkyl carbonate, wherein the catalyst is formed by activating a catalyst precursor using alcohol, wherein alcohol is R3—OH, and R3 is C1-12 alkyl group or C5-12 aryl or heteroaryl group. The catalyst precursor is formed by reacting Sn(R1)2(L)2 and Ti(OR2)4, and Sn(R1)2(L)2 and Ti(OR2)4 have a molar ratio of 1:2 to 2:1. R1 is C1-10 alkyl group, R2 is H or C1-12 alkyl group, and L is O—(C?O)—R5, and R5 is C1-12 alkyl group.

Abstract: A highly sensitive allergen measurement method is provided. A method for detecting an allergen in a sample, comprising: treating a sample with a protease; and detecting presence or absence of an allergen marker in the enzyme-treated sample by analysis that utilizes chromatographic separation. The allergen comprises buckwheat and wheat.

Abstract: An isotope production system, emanation generator, and process are disclosed for production of high-purity radioisotopes. In one implementation example, high-purity Pb-212 and/or Bi-212 isotopes are produced suitable for therapeutic applications. In one embodiment the process includes transporting gaseous radon-220 from a radium-224 bearing generator which provides gas-phase separation of the Rn-220 from the Ra-224 in the generator. Subsequent decay of the captured Rn-220 accumulates high-purity Pb-212 and/or Bi-212 isotopes suitable for direct therapeutic applications. Other high-purity product isotopes may also be prepared.

Abstract: A method for multi-camera self-supervised depth evaluation is described. The method includes training a self-supervised depth estimation model and an ego-motion estimation model according to a multi-camera photometric loss associated with a multi-camera rig of an ego vehicle. The method also includes generating a single-scale correction factor according to a depth map of each camera of the multi-camera rig during a time-step. The method further includes predicting a 360° point cloud of a scene surrounding the ego vehicle according to the self-supervised depth estimation model and the ego-motion estimation model. The method also includes scaling the 360° point cloud according to the single-scale correction factor to form an aligned 360° point cloud.

Abstract: A method of manufacturing a semiconductor device, the method including forming a photoresist material layer on a lower film, the photoresist material layer including a crosslinking molecule having a molecular weight of about 1,000 to about 4,000; exposing a partial region of the photoresist material layer; removing an unexposed portion of the photoresist material layer to form a photoresist pattern; and processing the lower film using the photoresist pattern, wherein the crosslinking molecule includes a perfluoro alkyl moiety, the perfluoro alkyl moiety including a carbon-fluorine bond that dissociates in response to the exposing of the partial region of the photoresist material layer.

Abstract: Provided herein, in some embodiments, are methods for analyzing immune cells in a blood sample from a subject having, suspected of having, or being at risk for bacterial sepsis. The present disclosure is based, at least in part, on the finding that certain immune cells are expanded in subjects having sepsis compared to healthy subjects.

Abstract: Provided is a thin-film structure including a substrate, a nanocrystalline graphene layer provided on the substrate, and a two-dimensional material layer provided on the nanocrystalline graphene layer. The nucleation density of the two-dimensional material layer is 109 ea/cm2 or more according to the nanocrystalline graphene layer, and accordingly, a two-dimensional material layer having an improved uniformity may be formed and a time duration for forming the two-dimensional material layer may be greatly decreased.

Abstract: A system of a multi-rotor aircraft that capitalizes on the advantages of fixed wing elements combined with rotary wing structures. The fixed wing elements can help to generate lift once the aircraft is airborne and can thus reduce the need for larger lifting rotors which can allow for longer flight times and distances. Additionally, the systems disclosed herein take advantage of a partial in-wing configuration with a number of rotors to reduce the overall footprint of the vehicle while maintaining the flight efficiency that comes with combining features of fixed and rotary wing elements, and increasing operator safety by shrouding rotating parts. The unique configurations allow for a decoupling of the pitch, yaw and roll authority to reduce the complexity in control systems and improve the flight efficiency of the aircraft. Additional configurations implement the use of smaller thrust rotors that can be used to generate thrust as well as control yaw and thus counteract any remaining unbalanced torque.

Abstract: A device and a method for experimental exploitation of natural gas hydrates in full-sized production wells are provided. The device includes a full-diameter well, and the full-diameter well includes a heating circulation tube, a temperature sensor tube, an upper sealing unit and a lower sealing unit. Perforations are provided along a body of the full-diameter well. A reactor includes an upper cover, a lower cover, and a reactor body. The method is conducted by using the device and the reactor. The device and method allow simulation of sand-control wellbores in actual exploitation of natural gas hydrates, and realize horizontal and vertical sand-control experiments.

Abstract: The present invention relates to a composition for preventing or treating central nerve system diseases, and by means of a compound according to one aspect, by inhibiting the death of adult hippocampal neural stem cells caused by stress and preserving the number of neural stem cells, the composition can be utilized in the prevention, amelioration, or treatment of mental diseases or neurodegenerative diseases, or in the prevention or amelioration of stress.