Abstract: A device, method, and non-transitory computer readable medium for fractional order dynamic inversion control of nonlinear systems under the influence of a disturbance. The method for fractional order dynamic inversion control includes receiving a mathematical model of a controlled device, the mathematical model including a set of movement trajectories, wherein the movement trajectories include control objectives, formulating a first set of linear, time-varying, fractional order differential equations from the mathematical model, the first set including dynamic constraints on the control objectives, transforming the first set into linear equations by differentiating a norm measure function along the movement trajectories, thus generating a second set of fractional order differential equations, and determining a control signal for controlling the movement trajectories in the presence of disturbances by dynamically inverting the second set of fractional order differential equations.

Abstract: A device, method, and non-transitory computer readable medium for interactive 3D visualization of ultrasound images of a supraspinatus tendon injury. Ultrasound images are acquired of a region in which the supraspinatus tendon injury is suspected. The ultrasound images are preprocessed, and energy of the preprocessed ultrasound images is minimized. A set of supraspinatus tendon images are extracted from low energy preprocessed ultrasound images. A morphological operation is performed on the set of supraspinatus tendon images to generate a smoothed set of supraspinatus tendon images. A binary mask is applied to the smoothed set of supraspinatus tendon images to detect boundary points of the supraspinatus tendon and generate a set of segmented image frames. The set of segmented image frames are arranged based on spatial position of each segmented image frame with respect to the supraspinatus tendon. A 3D representation of the supraspinatus tendon is reconstructed and rendered on a display.

Abstract: A method and a system of distributed estimation using q-diffusion least mean squares (qDiff-LMS) to modify adaptive filter weights in a decentralized wireless sensor network of N nodes is described. The method includes receiving, at each node, k, a local estimate of a previous time instance weight, wk(i?1), of an adaptive filter of each neighboring node, l, where l=1, 2, . . . , M, combining the local estimates of the previous time instance weights to generate a linear combination of global diffused weights, Øk(i?1), measuring, for each node k, an output, yk(i), of the adaptive filter of the node k, calculating, for each node k, a desired response, dk(i); generating, for each node k, an estimation error, ekCTA(i) by subtracting the output, yk(i) from the desired response, dk(i), and updating the global diffused weights by adding a portion of the estimated error to the global diffused weights.

Abstract: A method for detecting MERS-CoV at high sensitivity and specificity using IgY antibodies that bind to MERS-CoV N protein, its fragments and domains. Isolated or purified IgY monospecific antibodies to MERS-CoV N protein.

Abstract: A supercoil filtration unit is provided. The supercoil filtration unit includes an outer coil, and an inner coil disposed within the outer coil. The inner coil includes a plurality of hollow fiber membranes which are aligned and arranged into a helical bundle containing multiple turns of the inner coil per turn of the outer coil. The supercoil filtration unit further includes a feed inlet, a permeate outlet, and a retentate outlet. The feed inlet is disposed upon the outer coil and in fluid communication with a first interior volume. The permeate outlet is disposed upon the outer coil at a location distant from the feed inlet and in fluid communication with a second interior volume. The retentate outlet is disposed upon the outer coil at a location distant from the feed inlet and in fluid communication with the first interior volume.

Abstract: Methods and apparatuses are provided for estimating a path of an aerial vehicle engaged in attacking network devices in a wireless communication network. A distance function corresponding to the aerial vehicle and a boundary node is determined based on an initial coordinate location of the aerial vehicle and an initial coordinate location of the boundary node. A function of jamming power received at the boundary node from the aerial vehicle is determined based at least on the first distance function and a transmission power of the boundary node. The function of jamming power represents a power associated with a jamming signal received from the aerial vehicle at the boundary node. A trajectory of the aerial vehicle at a plurality of time periods is estimated by the boundary node with an extended Kalman filter. The extended Kalman filter is determined based on the function of jamming power.

Abstract: The invention pertains to liposomes containing an oil-in-water emulsion of a selected combination of at least ten different essential plant oils produced with phospholipids found in human membranes and methods for treating respiratory diseases, disorders or conditions by administering the liposomes into the nose and respiratory system.

Abstract: Provided are a self-nanoemulsifying 3D printer ink composition and a method of using such composition to manufacture a 3D-printed tablet having compartmentalized active pharmaceutical ingredients. In particular, the 3D-printed tablet composition includes glimepiride and/or rosuvastatin in a curcuma oil based self-nanoemulsifying drug delivery system (SNEDDS). The disclosure also provides a method of treating a metabolic disorder or disease by administering a therapeutically effective amount of the 3D-printed tablet to a subject in need thereof.

Abstract: The invention pertains to liposomes containing an oil-in-water emulsion of a selected combination of at least ten different essential plant oils produced with phospholipids found in human membranes and methods for treating respiratory diseases, disorders or conditions by administering the liposomes into the nose and respiratory system.

Abstract: A tissue splitting device for splitting a harvested soft tissue to provide a layer of tissue having a uniform thickness and methods for tissue transplantation using uniform layers of tissue.

Abstract: A sustained-release formulation of 5-fluorouracil (5-FU) providing a polymeric coating in a nanosuspension comprising sodium alginate and carrageenan for oral administration. The nanosuspension forms an insoluble sedimenting gel in the low pH environment of the stomach to speed gastric emptying. The sedimented insoluble gel becomes soluble in the pH environment of the small intestine and is transported to the colon where 5-FU is released at a predictable rate. The targeted delivery to the colon inhibits loss of 5-FU in the gastrointestinal tract and increases 5-FU exposure to cancerous cells in the colon.

Abstract: An organic light emitting diode (OLED) utilizes dysprosium incorporated tris-(8-hydroxyquinoline) aluminum (Alq3-Dy) as the emissive layer. The OLED, which can be fabricated as a multi-layer device with each layer having a thickness of 30-300 nm, provides a luminance value at a voltage ranging from 24V to 30V of 3000-15000 cd/m2. In comparison to similar OLEDs which utilize pure Alq3, the diodes with the Alq3-Dy layer provide an electroluminescence intensity 20 times higher than diodes with a pure Alq3 layer (Alq3 OLED). In addition, the peak position (EL emission band) of the Alq3-Dy OLED is shifted to the higher wavelength side by 10 nm compared to that of the pure Alq3 OLED (from 515 nm to 525 nm).

Abstract: An ophthalmic formulation comprising transethosomes is provided. The transethosomes include a phospholipid, an edge activator, ethanol, and ketoconazole, wherein a surface of the transethosome is modified with a cationic charge inducing agent. The transethosomes may be incorporated into in situ gelling or hydrogel compositions. The formulations are useful for the sustained delivery of ketoconazole to the posterior eye segment of a subject.

Abstract: A method of synthesizing nanoparticles comprising TiO2 and marine-based materials is provided. The method comprises mixing a solution containing a titanium precursor with a marine plant extract to form a colloidal suspension; aging the colloidal suspension to form a gel; drying the gel; and grinding the gel to obtain a powder comprising nanoparticles comprising TiO2 and marine-based materials. Paint formulations comprising the nanoparticles and methods of using the same are also provided.

Abstract: Nanoparticles having radially-oriented pores are fabricated from a noble metal. The pores have a specific geometrical shape, such as a circle, triangle, hexagon or other polygon. The nanoparticles are administered to a subject to form a nanoparticle-loaded tumor, which is targeted with a radiation beam as part of a radiotherapeutic treatment. The pores redirect photons of the radiation beam to intensify and enhance the dose received by tumor cells, while concomitantly reducing the dose received by surrounding cells and/or tissues. The nanoparticles may be combined with a radiosensitizing drug or agent, administered together or separately, to form a dose-enhancement composition that further intensifies the received dose of radiation at the target.

Abstract: Devices, methods, and non-transitory computer readable media perform steps for securing communications in a Multi-User (MU), Massive, Multiple Input Multiple Output (MIMO) network. The base station estimates an initial precoding matrix based on a first estimated value of a signal to interference plus noise ratio (SINR) and determines a kth user device outage probability value and an eavesdropper device outage probability value associated with the eavesdropper device. An optimized beamformer weight matrix is determined based on the user device outage probability value and the eavesdropper device outage probability value. The base station determines whether the optimized beamformer weight matrix satisfies at least one outage condition. When the outage condition is satisfied, the base station transmits the optimized beamformer weight matrix to each remote radio head, which transmits downlink signals using a kth beamformer vector of the optimized beamformer weight matrix.

Abstract: Provided are methods of using oleanolic acid and derivatives for treating coronavirus infection. The method includes using propargyl-moiety containing oleanolic acid derivatives for inhibiting coronavirus growth by impairing the viral replication of SARS-CoV-2 through inhibition of the viral function of SARS-CoV-2 main protease.

Abstract: A 15-level multilevel inverter circuit includes an outer circuit, an inner circuit, a polarity changing circuit and a computing device. The outer circuit and the inner circuit include a plurality of DC voltage supplies. Each DC voltage supply has a positive and a negative terminal. The outer circuit, the inner circuit and the polarity changing circuit include a plurality of unidirectional power switches. Each unidirectional power switch is a transistor with a diode connected in parallel to the transistor. The computing device is configured to provide control signals to the gates of the plurality of the unidirectional power switches of the outer circuit and the inner circuit to add or subtract the voltage of each of inner DC voltage supplies to form square waveforms approximating sinusoidal waveforms, and to the gates of the plurality of the unidirectional power switches of the polarity changing circuit to switch the polarity of the voltage.

Abstract: A multi-level switched capacitor boost inverter includes a series connection of a two-switched capacitor circuit, a source module and at least one one-switched capacitor circuit. Level-shifted pulse width modulation is used to apply gate pulses to the switches. The multi-level switched capacitor boost inverter uses only three capacitors and a single DC voltage source to generate thirteen voltage levels at load terminals with a voltage gain of three. The capacitors of the two-switched capacitor circuit are self-balancing. Additional one-switched capacitor circuits can be added in series with the inverter. Each additional one-switched capacitor circuit increases the number of levels and increases the gain by one.

Abstract: A 15-level multilevel inverter circuit includes an outer circuit, an inner circuit, a polarity changing circuit and a computing device. The outer circuit and the inner circuit include a plurality of DC voltage supplies. Each DC voltage supply has a positive and a negative terminal. The outer circuit, the inner circuit and the polarity changing circuit include a plurality of unidirectional power switches. Each unidirectional power switch is a transistor with a diode connected in parallel to the transistor. The computing device is configured to provide control signals to the gates of the plurality of the unidirectional power switches of the outer circuit and the inner circuit to add or subtract the voltage of each of inner DC voltage supplies to form square waveforms approximating sinusoidal waveforms, and to the gates of the plurality of the unidirectional power switches of the polarity changing circuit to switch the polarity of the voltage.