Abstract: Disclosed is a multi-dimensional gas chromatography chip with a modulator. The multi-dimensional gas chromatography chip includes a chip body including first to third substrates; first micro channel pattern parts including first micro channels; second micro channel pattern parts including second micro channels; a gas inlet to supply a mobile phase; a gas outlet to discharge the mobile phase; position alignment markers formed on one surface of the first substrate, both surfaces of the second substrates and one surface of the third substrate; a first stationary phase spin-coated between the first and second substrates and a second stationary phase spin-coated between the second and third substrates; and a modulator provided in a region serving as an inlet side of the first micro channel pattern parts as well as an outlet side of the second micro channel pattern parts.
Abstract: The present invention relates to a device for obtaining the ion source of a mass spectrometer using an ultraviolet diode and a CEM module, having the purpose of inducing initial electron emission using a CEM module and by radiating ultraviolet photons emitted from the ultraviolet diode to the entrance of the CEM module to obtain a large amount of amplified electron beams from the exit and to produce electron beams the emission times of which are accurately controlled at low temperature and at low power.
Abstract: A liquid medium plasma discharge generating apparatus includes a main body; a power electrode, provided at one side within the main body, for receiving electric power; a diaphragm member provided within the main body, and consisting of a dielectric defining one or more holes or slits; and a liquid medium charged inside the main body, wherein a ground electrode may be further provided in the main body, opposite the power electrode with the diaphragm member therebetween, whereupon the diaphragm member is arranged contacting the ground electrode.
Type:
Grant
Filed:
July 21, 2010
Date of Patent:
January 6, 2015
Assignee:
Korea Basic Science Institute
Inventors:
Dong Chan Seok, Tai Hyeop Loh, Seung Ryul Yoo, Yong Cheol Hong, Bong Ju Lee
Abstract: A method for preparing hydrophobic gold nanoparticles includes adding 1,2-dichlorobenzene as a solvent to gold precursor and using oleylamine and oleic acid with volume ratio of 7.5:2.5 to 5:5 as surfactants. The size of the prepared gold nanoparticles can be controlled over a broad range and may be utilized in various fields such as bio-imaging, photonic crystallization, sensors, organic catalysts, surface enhanced raman spectrum, electronic devices, etc. Further, a method for colorimetric detection of a strong acid uses hydrophilic nanoparticles that are phase transited from the prepared hydrophobic gold nanoparticles. Up to 5 ppm of low content hydrochloric acid can be detected utilizing phase transited hydrophilic nanoparticles in the colorimetric detection method, and the gold nanoparticles that were used in the detection of strong acid can be reused without loss of activity through neutralization with bases.
Type:
Application
Filed:
November 22, 2013
Publication date:
December 25, 2014
Applicant:
Korea Basic Science Institute
Inventors:
Gae Hang LEE, Doo Ri BAE, Yeon Suk CHOI
Abstract: The present invention relates to an ultraviolet diode and an atomic mass analysis ionization source collecting device using an MCP. In the manufacturing of a portable atomic mass analyzer, an object of the present invention is to use an MCP electron multiplier plate, whereby ultraviolet photons emitted from an ultraviolet diode are irradiated on a front surface plate of the MCP electron multiplier plate to induce primary electrons, an amplified electron beam is collected from the electrons, and an electron beam is generated at a low temperature and low power and having a discharge time that is accurately controlled.
Abstract: The present invention relates to a peptide marker for cancer diagnosis and a cancer diagnosis method using the same, more precisely to a peptide marker for cancer diagnosis screened by the following steps: separating and concentrating glycoproteins including a certain glycan chain related to the occurrence of cancer; hydrolyzing the glycoproteins to obtain polypeptides; and quantitatively analyzing the polypeptides to identify certain polypeptides that can track quantitative changes in glycoproteins glycosylated in a specific manner by the occurrence of cancer, and to a cancer diagnosis method using the said peptide marker.
Abstract: The present invention relates to a gaseous sample injection valve. The gaseous sample injection valve includes a middle body injecting a fixed amount of a gaseous sample into the vacuum chamber of a mass spectrometer, the middle body being constituted by a gaseous sample injection tube, a gaseous sample discharge tube, a storage part, and a vacuum chamber connection tube; an upper body accommodating a first solenoid coil, a first plunger, and a first packing; and a lower body accommodating a second solenoid coil, a second plunger, and a second packing. The gaseous sample injection valve according to the present invention may be miniaturized to utilize a lightweight portable mass spectrometer. Also, the vacuum pump may be reduced in load to extend the operation life-cycle of the vacuum pump. In addition, when the gaseous sample is analyzed by using the mass spectrometer, a uniform mass spectrum with respect to the gaseous sample may be obtained.
Abstract: Disclosed is a method of preparing high crystalline nanoporous titanium dioxide, in which the high crystalline nanoporous titanium dioxide, which is harmless to the human body and self-purified through the decomposition of organic matters, is prepared in mass production at the room temperature through a simply synthesis method. The method includes the steps of (a) mixing a titanium precursor and a surfactant in a solvent and performing a sol-gel reaction at a room temperature; (b) maturing a reactant obtained through the sol-gel reaction at the room temperature; (c) filtering the matured reactant and washing the matured reactant; and (d) drying the washed reactant to obtain titanium dioxide having nanopores.
Type:
Grant
Filed:
February 29, 2012
Date of Patent:
October 7, 2014
Assignee:
Korea Basic Science Institute
Inventors:
Hae-Jin Kim, Jou-Hahn Lee, Soon-Chang Lee, Hyun-Uk Lee, Won-Ki Hong, Hye-Ran Kim, Jung-Hye Seo
Abstract: The present invention relates to a pharmaceutical composition for preventing or treating diabetes or fatty liver, and more specifically relates to a pharmaceutical composition for preventing or treating diabetes or fatty liver containing a CYP4A (cytochrome P450A) inhibitor as an active ingredient. According to the present invention, the CYP4A inhibitor suppresses endoplasmic reticulum stress, reduces the blood insulin concentration and suppresses apoptosis of liver cells, and hence exhibits effects in preventing or treating diabetes or fatty liver.
Type:
Application
Filed:
February 11, 2014
Publication date:
September 18, 2014
Applicant:
Korea Basic Science Institute
Inventors:
Gun-Hwa Kim, Soohyun Kim, Jong-Soon Choi, Seung II Kim, Edmond Changkyun Park
Abstract: Iron oxide nano contrast agents for Magnetic Resonance Imaging which have superior T2 contrast effect, and also can be used as a storage or a carrier for drugs and so on, are disclosed. The iron oxide nano contrast agents can be prepared by the steps of: coating surfaces of hydrophobic FeO nanoparticles with a coating material selected from the group consisting of polyethylene glycol-phospholipid conjugate, dextran, chitosan, dimercaptosuccinic acid and mixtures thereof in an organic solvent to form hydrophilic FeO nanoparticles having hydrophilic surfaces and dispersibility in water; dispersing the hydrophilic FeO nanoparticles in water to oxidize FeO; and exposing the oxidized hydrophilic FeO nanoparticles to an acidic buffer to dissolve and remove interior unoxidized FeO portions, and thereby to form Fe3O4 nanoparticles having an interior space.
Type:
Grant
Filed:
July 31, 2013
Date of Patent:
September 9, 2014
Assignee:
Korea Basic Science Institute
Inventors:
Chulhyun Lee, Sung Lan Jeon, Min Kyung Chae, Jee-Hyun Cho, Eun Ju Jang
Abstract: The present invention relates to an apparatus for sterilization which may be applied to a medical dry sterilizer, and more particularly, to an apparatus which injects hydrogen peroxide so as to generate plasma and OH radicals which are effective in sterilization, so as to achieve the sterilization of a treated object. According to the present invention, the apparatus for sterilization comprises: a sterilizing reactor in which sterilization is performed on a treated object; a vacuuming unit which is equipped with a vacuum pump connected to the sterilizing reactor and which vacuumizes the interior of the sterilizing reactor; a hydrogen-peroxide supply unit which supplies hydrogen peroxide in a gas state to the interior of the sterilizing reactor; and a microwave-plasma generating unit which generates plasma using microwaves.
Abstract: The present invention relates to a method of determining a routing path in a communication network in which a plurality of logical networks shares a physical network, and more particularly to such a method of determining a routing path of data, in which multiple routing paths from a source node to a destination node are created based on a change in the dynamic state of a plurality of nodes constituting a logical network, and routing costs for the created multiple routing paths are calculated based on a routing registration message received from the plurality of nodes, and a process time transition value and a transmission time transition value shared by the plurality of nodes.
Abstract: The present invention relates to an apparatus and method for controlling a pipeline-type ion cyclotron resonance mass spectrometer, in which an ion trap unit of the ion cyclotron resonance mass spectrometer is capable of using two digitizers at the same time, thus enabling a measurement process for detecting an electrical signal which indicates the mass of ions corresponding to a specific purpose, and another measurement process for detecting another electrical signal which indicates the mass of ions corresponding to another specific purpose, to be simultaneously performed. Accordingly, it is an aim of the present invention to provide an apparatus and method for controlling a pipeline-type ion cyclotron resonance mass spectrometer, which can overcome the problems of time delay among control procedures, and can present a signal detection step wherein an excitation electrode is utilized to improve the sensitivity and speed of signal detection.
Type:
Grant
Filed:
November 16, 2010
Date of Patent:
August 5, 2014
Assignee:
Korea Basic Science Institute
Inventors:
Seung Yong Kim, Hyun Sik Kim, Jong Shin Yoo
Abstract: The present invention provides a system and method of predicting the initial cooling of a superconducting magnet, which can predict the change in initial cooling temperature of a superconducting magnet when the superconducting magnet is cooled using an ultra-low refrigerator. In the system and method, the change in cooling temperature of a superconducting magnet can be accurately predicted by classifying influence factors related to the cooling of a superconducting magnet into a plurality of control volumes and inducing a governing equation with respect to each of the control volumes. Based on this system and method, the reliability of basic data required to design an apparatus for measuring a high magnetic field for forming an ultralow-temperature environment can be greatly improved.
Abstract: An ion trap mass spectrometer is provided, including: an electron emitter; an ion trap storing ions generated by ionization resulting from an impact with electrons emitted from the electron emitter; a secondary ion filter for blocking out secondary ions generated due to ions selectively released by the ion trap; and a detector detecting ions selectively released from the ion trap, wherein the electron emitter, the ion trap, the secondary ion filter, and the ion detector are arranged on the same axis, so that a pure mass spectrum can be measured by excluding the secondary ions which are causes of background noise signals in the procedure of detection of the ions by the ion trap mass spectrometer.
Abstract: The present invention is directed to a magnetic sensor using a spin transfer torque device, including a spin transfer torque device configured such that the magnetization direction thereof is varied by current, a bipolar pulse source configured to apply bipolar pulses to the spin transfer torque device in order to control the coercive field and sensitivity of the spin transfer torque device, and a signal processing unit configured to calculate magnetic susceptibility or magnetic resistance by counting the parallel (P) or anti-parallel (AP) states of the spin transfer torque device in response to the applied bipolar pulses.
Abstract: Provided are a controller and a control method for improving signal performance of an ion cyclotron resonance mass spectrometer. The controller and control method apply electric signals for causing ions injected into an ion trap of the ion cyclotron resonance mass spectrometer to be injected to the center of the trap as close as possible to trap electrodes, and adjust biased ion motion by appropriately adjusting signals of trap electrodes for causing the injected ions to make ion motion, thereby improving the fidelity of ion signals. The control method for improving signal performance of an ion cyclotron resonance mass spectrometer includes an ion position adjustment process and an ion signal detection process.
Type:
Grant
Filed:
October 31, 2011
Date of Patent:
May 13, 2014
Assignee:
Korea Basic Science Institute
Inventors:
Seung Yong Kim, Hyun Sik Kim, Myoung Choul Choi, Jong Shin Yoo
Abstract: The present invention relates to a device for obtaining the ion source of a mass spectrometer using an ultraviolet diode and a CEM module, having the purpose of inducing initial electron emission using a CEM module and by radiating ultraviolet photons emitted from the ultraviolet diode to the entrance of the CEM module to obtain a large amount of amplified electron beams from the exit and to produce electron beams the emission times of which are accurately controlled at low temperature and at low power.
Abstract: Provided is an imaging system which includes an optical fiber array probe unit integrated with an endoscope unit, thereby simultaneously measuring structural information and functional information of a sample. The optical fiber array probe unit includes an optical fiber array probe integrated with lenses including an optical fiber lens with a lens surface of a predetermined radius of curvature in which one ends of optical fibers are integrally connected with each other by heating a predetermined region including the one ends of two of the optical fibers using a heating means, as an optical fiber array probe integrated lens on which the light transmitted from the light source is incident and which guides light reflected from the sample, and a detector for selectively detecting the light transmitted from the optical fiber array probe integrated with lenses in a predetermined range of wavelength.
Type:
Grant
Filed:
December 7, 2012
Date of Patent:
April 15, 2014
Assignee:
Korea Basic Science Institute
Inventors:
Ki Soo Chang, Seon Young Ryu, Sun Cheol Yang, Geon Hee Kim, Hae Young Choi
Abstract: An apparatus for generating X-ray may include: a plasma chamber; a magnet unit for applying a magnetic field to the plasma chamber, the magnet unit configured to allow the control of the magnitude of the minimum magnetic field in the plasma chamber without change in structure; a microwave generator for applying microwaves to the plasma chamber; a reaction gas injected into the plasma chamber for generating X-ray through electron cyclotron resonance by the magnetic field and the microwaves; a variable guide for focusing the generated X-ray; and a variable extractor for outputting the focused X-ray from the plasma chamber.
Type:
Grant
Filed:
May 18, 2012
Date of Patent:
April 8, 2014
Assignee:
Korea Basic Science Institute
Inventors:
Byoung Seob Lee, Mi Sook Won, Jang Hee Yoon, Jin Yong Park, Se Yong Choi