Patents Assigned to Nipro Corporation
  • Patent number: 8496626
    Abstract: Provided is a safety needle assembly for protecting a needle point, a safety type needle assembly having a curved portion, to which an erroneous piercing preventing mechanism is added, or a safety type Hoover needle assembly thereby to prevent the piercing accident. The safety needle assembly includes a needle having a point at its leading end, a hub for holding the root end portion of the needle, and a leading end protecting portion. The safety needle assembly further includes a restricting portion for restricting the distance between the needle and the hub, in that the leading end protecting portion includes a mechanism for warping the needle point, when the leading end protecting portion moves the leading end of the needle to a projecting position, thereby to accommodate the needle point in the inner side of the leading end protecting portion, so that the leading end of the needle is protected.
    Type: Grant
    Filed: April 27, 2007
    Date of Patent: July 30, 2013
    Assignee: Nipro Corporation
    Inventors: Yuki Hiraoka, Ken Suzuki
  • Patent number: 8439941
    Abstract: A disposable lancing device including: a lancet housed in a housing and urged by a spring member such that a puncture member provided at a distal end of the lancet is adapted to extend out from the housing so as to carry out a puncturing operation; a locking ring disposed within the housing such that the lancet is allowed to displace in an extension direction through the locking ring; a locking protrusion provided to the lancet and adapted to be engaged by the locking ring so as to hold the lancet in a puncture-ready position located deep in the housing with the spring member being compressed; and an operating member adapted to carry out the puncturing operation by rotating the locking ring so as to disengage the locking protrusion from the locking ring and displace the lancet in the extension direction by means of the spring member.
    Type: Grant
    Filed: January 26, 2011
    Date of Patent: May 14, 2013
    Assignee: Nipro Corporation
    Inventors: Kohzo Ishikura, Tomohiro Uchimura, Ken Suzuki
  • Patent number: 8426451
    Abstract: An oral solid preparation including a base compound and a powdery or granular additive colored with a colorant and a method of manufacturing an oral solid preparation including the steps of: coloring an additive with a colorant, mixing the resultant additive with a base compound, and tableting the mixture.
    Type: Grant
    Filed: April 25, 2008
    Date of Patent: April 23, 2013
    Assignee: NIPRO Corporation
    Inventors: Junichi Yokoe, Keisuke Nakajo, Naohisa Katayama, Toshiya Kai
  • Publication number: 20130096493
    Abstract: An administration device can discharge a prescribed, equal amount of medicine a number of times by spraying. A spraying device includes a barrel; a gasket provided slidably movable in liquid-tight manner in the barrel; a rod coupled to a base end of the gasket; and a regulating member provided on the barrel, having a projection that can slidably fit with the guide groove. The guide groove includes at least first and second continuous administering grooves. The second administering groove is configured to include a transitional portion extending in the circumferential direction with a groove wall on the base end side aligned with the base end of the first administering portion, and a second administering portion extending from the transitional portion to a base end along the longitudinal direction. An energizing protrusion engageable with the projection is provided at a boundary between the transitional portion and the second administering portion.
    Type: Application
    Filed: June 28, 2011
    Publication date: April 18, 2013
    Applicant: NIPRO CORPORATION
    Inventors: Tomohiko Kubo, Teruhisa Hirobe
  • Publication number: 20130090596
    Abstract: In a pre-filled syringe having an intermediate gasket, a liquid drug is enclosed in the second chamber located on the base end side with respect to the intermediate gasket while a powdered drug is enclosed in the first chamber located on the front end side with respect to the intermediate gasket. The intermediate gasket has at least two layers including a front end layer corresponding to a wall of the first chamber and a base end layer corresponding to a wall of the second chamber, and also has a low water-absorptive layer in the layer on the base end side with respect to the front end layer. The base end layer is formed of a material having low water-absorptivity and not lowering a pH of the liquid drug.
    Type: Application
    Filed: June 8, 2011
    Publication date: April 11, 2013
    Applicant: NIPRO CORPORATION
    Inventors: Takashi Asai, Tsutomu Takahashi, Kenyu Ito, Atsushi Ishikawa
  • Patent number: 8375688
    Abstract: A package for a cryopreservation container including at least an adhesive fluoropolymer film. The package for a cryopreservation container makes it possible to store blood, rare cells and vital tissues in a very low temperature environment without any damage to the container. Further, the sealing strength resulting from heat sealing after placing a cryopreservation container in the packages is very good. Therefore, liquid nitrogen can be inhibited from entering the inside and thus contamination with bacteria, viruses or the like contained in liquid nitrogen can be avoided and the package can be prevented from being broken by expansion of intruder liquid nitrogen on the occasion of thawing. Also disclosed is a method for packaging a cryopreservation container and a method of producing a package for a cryopreservation container.
    Type: Grant
    Filed: June 23, 2011
    Date of Patent: February 19, 2013
    Assignees: Nipro Corporation, Daikin Industries, Ltd.
    Inventors: Kazuki Ishihara, Hideaki Murahashi, Naomi Nakatani, Yoshihiro Yoshikawa, Akio Shirasu, Hidenori Ozaki
  • Patent number: 8371859
    Abstract: The kit for suppressing drug craving K is used by connecting an instrument for suppressing drug craving 1 to a syringe 2 and the instrument for suppressing drug craving 1 has a cylindrical housing 11, a pouch 12 provided in the housing and containing pseudo-blood B and a connecting member 13 with which the distal end of a syringe is coupled and which cause the syringe to communicate with the interior of the pouch. When the syringe accommodating pseudo-drug M is connected to the instrument and the plunger is moved forward (pseudo-priming), the pseudo-drug M flows into a pouch and the pouch inflates (FIG. 2(b)), and if the plunger 4 is pulled back from this condition, the pouch 12 deflates and the pseudo-blood B flows back from the pouch 12 to the syringe 2 (flashback) (FIG. 2(C)).
    Type: Grant
    Filed: October 15, 2008
    Date of Patent: February 12, 2013
    Assignees: National Hospital Organization, Nipro Corporation
    Inventors: Shinji Hirai, Mitsuru Hasegawa, Takeshi Ohguro
  • Patent number: 8333750
    Abstract: A label enables a user to recognize information necessary when using a medicine bag in a reliable fashion. The label includes a base part indicating thereon basic information including at least information on ingredients of medicines accommodated in a medicine bag and a detachable part detachably joined to the base part. The detachable part is so shaped as to be attachable to such an area of the medicine bag that it becomes difficult to use the medicine bag when a surface of the area is covered, and the detachable part indicates thereon characteristic information including at least directions on use of the medicine bag.
    Type: Grant
    Filed: April 28, 2006
    Date of Patent: December 18, 2012
    Assignee: Nipro Corporation
    Inventors: Shinya Tanaka, Kiyoko Enosaki, Katsunori Takasugi, Yoshiharu Yamaguchi
  • Patent number: 8328826
    Abstract: The present invention provides a precursor for producing a tissue regenerating instrument that regenerates a tissue, including: a tube made of a biodegradable material provided with a lumen in a longitudinal direction; a rod made of a biodegradable material swellable with a softening solvent, fixed to an inner wall of the tube substantially parallel to the longitudinal direction of the tube; and an adhesive that fixes the rod to the inner wall of the tube, in which the rod in a non-swelled state has an occupied cross-sectional area perpendicular to the longitudinal direction that is smaller than a cross-sectional area of the lumen of the tube, and the occupied cross-sectional area perpendicular to the longitudinal direction of the rod in a saturated swelled state with the softening solvent is substantially the same as the cross-sectional area of the lumen of the tube.
    Type: Grant
    Filed: August 15, 2007
    Date of Patent: December 11, 2012
    Assignee: NIPRO Corporation
    Inventors: Nobutoshi Doi, Shunsuke Notazawa
  • Patent number: 8323881
    Abstract: A method of injecting cells into a biological tissue comprising thrusting injection needle (200) under microvibration into tissue (5) secured by suction to tissue suction means (210) and effecting injection of a cell suspension into the tissue through the needle. There is also provided an apparatus for cell injection into the biological tissue.
    Type: Grant
    Filed: July 2, 2004
    Date of Patent: December 4, 2012
    Assignees: Japan as represented by President of National Cardiovascular Center, Nipro Corporation
    Inventors: Toshiya Fujisato, Akio Kishida, Soichiro Kitamura
  • Publication number: 20120294947
    Abstract: Provided is an oral preparation that contains a medicinal component having an unpleasant taste and that has better qualities, for example, generation of an analogue can be reduced, better than oral preparations that are produced by conventional techniques and that contain a medicinal component having an unpleasant taste. This objective is achieved by adding a coating agent on the medicinal component and a disintegrator that has a carboxymethyl group.
    Type: Application
    Filed: December 28, 2010
    Publication date: November 22, 2012
    Applicant: NIPRO CORPORATION
    Inventors: Kennichiro Kuninobu, Yohei Hoashi, Naohisa Katayama, Toshiya Kai
  • Publication number: 20120286762
    Abstract: A container for measuring cellular electric potential after being mounted on an electric potential measuring device is provided comprising a container and an electrode substrate, the electrode substrate being attached to a lower end of the container so as to form a plurality of wells, wherein the container comprises a plurality of cylindrical portions whose upper and lower ends are open, the electrode substrate comprises a substrate and a plurality of measurement electrodes and a plurality of reference electrodes disposed on one surface of the substrate, the measurement electrodes and the reference electrodes at least comprise metal-plated copper wiring, a pair of a measurement electrode and a reference electrode are disposed on a bottom of each well, and the measurement electrodes and the reference electrodes are formed by a pre-plating method.
    Type: Application
    Filed: November 22, 2010
    Publication date: November 15, 2012
    Applicant: NIPRO CORPORATION
    Inventors: Shinji Morimoto, Yui Hagiwara
  • Patent number: 8287464
    Abstract: A metal needle is obtained by being dipped in a liquid selected from the group consisting of a strong acid solution of a metal, acetic acid, and butyl acetate, and then dried. Preferably, the strong acid solution of a metal to be used in the dipping treatment may be a nitric acid solution of a metal selected from the group consisting of a transition element, a lanthanoid, and an actinoid, for example, a nitric acid solution of a metal selected from the group consisting of palladium, gadolinium, germanium, beryllium, strontium, scandium, and samarium. The metal needle is a metal needle for insertion into the body that can be reliably imaged even when a general-purpose ultrasound imaging system is used, and thus is useful in confirming insertion of the needle into a blood vessel and arrival of the needle at an organ, and confirming the position of the needle when it is broken.
    Type: Grant
    Filed: March 31, 2008
    Date of Patent: October 16, 2012
    Assignee: Nipro Corporation
    Inventors: Hiroshi Hirota, Yoshiharu Iwase
  • Patent number: 8262685
    Abstract: A disposable lancing device including: a housing; a spring member; a lancet having a skin puncture needle, the spring member and the lancet being housed within the housing such that a needle tip of the skin puncture needle is adapted to be projected out from the housing under urging of the lancet by the spring member to perform skin puncture procedure; and a protective cap having a needle passage hole and covering the needle tip of the skin puncture needle, the protective cap being adapted to separate from the skin puncture needle and rotate so that the needle passage hole of the protective cap is positioned on a path of projection of the skin puncture needle, and the skin puncture procedure is performed with the protective cap supported on the housing.
    Type: Grant
    Filed: March 15, 2010
    Date of Patent: September 11, 2012
    Assignee: Nipro Corporation
    Inventors: Kohzo Ishikura, Ken Suzuki, Takeshi Yamaguchi
  • Publication number: 20120191122
    Abstract: Disclosed is a disposable blood collecting instrument that stably secures a sufficient volume of blood with a single puncture. A tip portion of a piercing body of a lancet contained within a housing projects by means of a biasing force of a spring assembly, and a surrounding area of an opening of the housing is made a transparent visible portion with a visible interior. Additionally, the disposable blood collecting instrument has been formed such that the spring assembly is contained within housing farther behind the piercing body than a position of the tip portion of the piercing body that has entered within the housing after piercing.
    Type: Application
    Filed: September 8, 2010
    Publication date: July 26, 2012
    Applicant: NIPRO CORPORATION
    Inventors: Tomohiro Uchimura, Kohzo Ishikura, Ken Suzuki
  • Patent number: 8211082
    Abstract: To provide a drug solution preparing kit which can be handled with ease in a substantially aseptic manner, and has no risk that a leakage of a drug solution such as a splash and a dispersion of an aerosol to an ambient environment occurs upon preparation of the drug solution There is provided a drug solution preparing kit including a pre-filled syringe and a transfusing tool, wherein the pre-filled syringe includes a sealing member which seals the tip end and can not be removed from the tip end, and that the transfusing tool includes a one-way valve which can discharge only gas from the system in an irreversible manner, and a filter which is provided so as to adjoin to the second communication channel with respect to the one-way valve.
    Type: Grant
    Filed: June 19, 2007
    Date of Patent: July 3, 2012
    Assignee: Nipro Corporation
    Inventors: Mitsuru Hasegawa, Atsushi Ishikawa, Suguru Oyagi, Takeshi Ohguro
  • Patent number: 8211362
    Abstract: A packaged blood purification device including a hollow fiber blood-processing device having a bundle of hollow fibers and a cylindrical container holding the bundle of hollow fibers; and a gas-impermeable container for packaging the hollow fiber blood-processing device. The hollow fiber blood-processing device is sealed together with an oxygen absorber in the gas-impermeable container, and is sterilized with radiation. The blood-processing device is produced by a method including the steps of sealing a hollow fiber blood-processing device in said gas-impermeable container together with an oxygen absorber, and radiation sterilizing the blood-processing device held in the sealed gas-impermeable container.
    Type: Grant
    Filed: September 23, 2004
    Date of Patent: July 3, 2012
    Assignee: Nipro Corporation
    Inventors: Toshiaki Masuda, Yuki Hatakeyama, Takashi Sunohara
  • Publication number: 20120119750
    Abstract: A cellular electric potential measuring container includes a container body and an electrode substrate, the electrode substrate being attached to a lower end of the container body so as to form a plurality of wells. The container body is made from resin and comprises a plurality of tubular portions whose upper and lower ends are open, each of the tubular portions comprises in an inner cavity a measurement portion tapered toward the lower end and having a measurement hole at the lower end, and further on an inner wall at least two retaining means retaining the measurement portion. The electrode substrate comprises a substrate body, with a plurality of measurement electrodes and a plurality of reference electrodes being disposed on one surface of the substrate body. The container body is attached to the surface of the substrate body on which the measurement electrodes and the reference electrodes are disposed, such that the measurement electrodes are exposed through the measurement holes.
    Type: Application
    Filed: July 23, 2010
    Publication date: May 17, 2012
    Applicants: REPROCELL INCORPORATED, NIPRO CORPORATION
    Inventors: Shinji Morimoto, Yui Hagiwara
  • Patent number: D681209
    Type: Grant
    Filed: February 15, 2011
    Date of Patent: April 30, 2013
    Assignee: Nipro Corporation
    Inventors: Shin-ichi Kawamura, Kazuhisa Ishihara, Naoaki Yasumura
  • Patent number: D687943
    Type: Grant
    Filed: February 16, 2011
    Date of Patent: August 13, 2013
    Assignee: Nipro Corporation
    Inventors: Susumu Kobayashi, Yukinori Ebara, Shin-ichi Kawamura, Takashi Arai, Kazuhisa Ishihara, Tomohiro Uchimura, Yuji Kuwahara, Sunsuke Kikumoto, Naoaki Yasumura