Patents Assigned to Nipro Corporation
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Patent number: 8957663Abstract: A container for measuring cellular electric potential after being mounted on an electric potential measuring device is provided comprising a container and an electrode substrate, the electrode substrate being attached to a lower end of the container so as to form a plurality of wells, wherein the container comprises a plurality of cylindrical portions whose upper and lower ends are open, the electrode substrate comprises a substrate and a plurality of measurement electrodes and a plurality of reference electrodes disposed on one surface of the substrate, the measurement electrodes and the reference electrodes at least comprise metal-plated copper wiring, a pair of a measurement electrode and a reference electrode are disposed on a bottom of each well, and the measurement electrodes and the reference electrodes are formed by a pre-plating method.Type: GrantFiled: November 22, 2010Date of Patent: February 17, 2015Assignee: Nipro CorporationInventors: Shinji Morimoto, Yui Hagiwara
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Patent number: 8926645Abstract: A disposable lancing device including: a lancet housed in a housing and urged by a spring member such that a puncture member provided at a distal end of the lancet is adapted to extend out from the housing so as to carry out a puncturing operation; a locking ring disposed within the housing such that the lancet is allowed to displace in an extension direction through the locking ring; a locking protrusion provided to the lancet and adapted to be engaged by the locking ring so as to hold the lancet in a puncture-ready position located deep in the housing with the spring member being compressed; and an operating member adapted to carry out the puncturing operation by rotating the locking ring so as to disengage the locking protrusion from the locking ring and displace the lancet in the extension direction by means of the spring member.Type: GrantFiled: April 17, 2013Date of Patent: January 6, 2015Assignee: Nipro CorporationInventors: Kohzo Ishikura, Tomohiro Uchimura, Ken Suzuki
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Publication number: 20140358218Abstract: Provided is a stent of a novel structure with which deflection of a line-shaped body during expansion is prevented and a substantially uniform expansion is achieved over an entire length thereof, and with which, after implantation, stent fracture and damage of body tissue can be prevented by the stent exhibiting a superior pliability and conformability to a shape of a somatic lumen. A stent having a cylindrical peripheral wall formed with a line-shaped body that extends in a helical form in a circumferential direction while reciprocating in an axial direction at a given amplitude. In the stent, connecting parts are formed to link portions of the line-shaped body that are adjacent in the axial direction, and a friable part is provided to rupture itself by being implanted in the somatic lumen and release a link made by the connecting parts.Type: ApplicationFiled: August 22, 2012Publication date: December 4, 2014Applicant: NIPRO CORPORATIONInventors: Kazuaki Mitsudo, Koji Akimoto
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Patent number: 8900212Abstract: A connection device includes a main holder including a syringe holder to be attached to a syringe and a cannula holder which includes a double-head cannula. The cannula holder is located at a retracted position retracted with respect to the syringe holder in the pre-use state, and is advanced to an advanced position abutting on the syringe holder in the use state. The connection device further includes a separation preventing mechanism which engages the syringe to prevent separation of the syringe from the syringe holder in the state where the cannula holder is located at the retracted position. When the cannula holder is located at the advanced position, the separation preventing mechanism releases an engagement state with the syringe to permit the separation of the syringe from the syringe holder.Type: GrantFiled: July 12, 2010Date of Patent: December 2, 2014Assignee: Nipro CorporationInventor: Tomohiko Kubo
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Patent number: 8900199Abstract: A needle tip protector is configured in such a manner that a flexible plate is provided to a protector main body over which an action ring is mounted and that the flexible plate undergoes flexural deformation when the action ring is moved to a predetermined position relative to the protector main body. When the flexible plate undergoes flexural deformation, a needle tip of an inner needle to which the protector main body is mounted is protected by a protection part placed at a distal end of the flexible plate. The needle tip protector is also provided with a slip-stop mechanism for preventing the action ring from slipping out of the protector main body in an axial direction of the needle.Type: GrantFiled: October 1, 2009Date of Patent: December 2, 2014Assignee: Nipro CorporationInventors: Katsunori Kawai, Tatsuya Kudo, Hiroyuki Nakagami
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Publication number: 20140316350Abstract: A bottomed, tubular hollow elastic body that opens toward an outlet side of a drug solution flow path is accommodated and arranged in an accommodation part formed in a housing, and a middle protrusion is provided protruding toward an inlet side of the drug solution flow path from a center part of a bottom wall of the hollow elastic body. Insertion of a male luer causes the bottom wall of the hollow elastic body to be elastically deformed so as to enter inside a peripheral wall, increasing the volume of the drug solution flow path, which is formed between an outer surface of the hollow elastic body and an inner surface of the accommodation part. Removing the male luer and canceling the elastic deformation of the hollow elastic body causes the volume of the drug solution flow path to be reduced.Type: ApplicationFiled: December 27, 2012Publication date: October 23, 2014Applicant: NIPRO CORPORATIONInventors: Takeshi Yamaguchi, Tomohiro Uchimura, Kohzo Ishikura
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Patent number: 8864737Abstract: To provide a drug solution preparing kit which can be handled with ease in a substantially aseptic manner, and has no risk that a leakage of a drug solution such as a splash and a dispersion of an aerosol to an ambient environment occurs upon preparation of the drug solution There is provided a drug solution preparing kit including a pre-filled syringe and a transfusing tool, wherein the pre-filled syringe includes a sealing member which seals the tip end and can not be removed from the tip end, and that the transfusing tool includes a one-way valve which can discharge only gas from the system in an irreversible manner, and a filter which is provided so as to adjoin to the second communication channel with respect to the one-way valve.Type: GrantFiled: March 7, 2012Date of Patent: October 21, 2014Assignee: Nipro CorporationInventors: Mitsuru Hasegawa, Atsushi Ishikawa, Suguru Oyagi, Takeshi Ohguro
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Patent number: 8864735Abstract: A bottle-type blow-molded plastic infusion container that can be set in an upright position. When liquid is discharged from the container, almost no dead space occurs in shoulder and bottom portions (required amount of air to be placed in the container to remove residual liquid is less). The blow-molded container has a mouth section (1), a neck section (2), the shoulder section (3), a barrel section (4), and the bottom section (5). The barrel section (4) has a pair of broad side faces (41, 41) and a pair of narrow side faces (42, 42). The bottom section (5) is formed in a shape symmetrical about a longitudinal axis of the bottom section (5) and bent inward in a V shape. Further, the shoulder section (3) has a pair of broad side faces (31, 31) and a pair of narrow side faces (32, 32). In the narrow side faces (32, 32) are formed grooves (33, 33) symmetrical about a longitudinal axis and bent inward in a V shape.Type: GrantFiled: September 25, 2007Date of Patent: October 21, 2014Assignee: Nipro CorporationInventors: Yoshihiko Sano, Hitoshi Futagawa, Toshihiro Kikuchi
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Patent number: 8864700Abstract: A plurality of heat transfer pipes have a circumferential portion arranged at a short distance from an inner surface of a heat exchanger case while they are bundled to form a pipe group and a first chord which retracts toward a center in a direction of cylinder diameter from an arc formed by the circumferential portion. The plurality of bundled heat transfer pipes are loaded in the exchange case such that the first chord and an inner surface of the heat exchange case on a side where a heat exchange medium inlet port is attached are opposed to each other. By making a flow of a heat exchange medium to each heat transfer pipe uniform, a heat exchanger capable of obtaining high heat exchange performance is obtained.Type: GrantFiled: February 15, 2011Date of Patent: October 21, 2014Assignee: Nipro CorporationInventors: Shin-ichi Kawamura, Kazuhisa Ishihara, Naoaki Yasumura
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Publication number: 20140303565Abstract: A nasal cavity administration container includes a body section including a medical fluid storage section having an opening and a plunger having a pressing part, and a plunger moving amount regulation member having a stopper and being engaged with the body section, an engagement with the body section being relieved only in a state where the pressing part abuts on the stopper. When the plunger is pushed into the medical fluid storage section, the plunger moves forward until the pressing part abuts on the stopper. The plunger is further pushed into the medical fluid storage section with the plunger moving amount regulation member detached from the body section. The nasal cavity administration container can administer a medical fluid easily and appropriately.Type: ApplicationFiled: May 11, 2012Publication date: October 9, 2014Applicant: NIPRO CORPORATIONInventors: Tomohiko Kubo, Teruhisa Hirobe
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Patent number: 8845591Abstract: A liquid medicine self-administration device including a flexible reservoir, an operating member, a pushing member to move with respect to the operating member and to induce pressure deformation of the reservoir, and engaging means engages the operating member. With the operating member engaged by the engaging means, the pushing member is relatively moved to the operating member based on restoring force of a spring member to push the reservoir by the pushing member. By disengaging means moving in unison with the pushing member, the engaging means is released from an engaged state with respect to the operating member, when the pushing member has moved to a predetermined location while pushing the reservoir.Type: GrantFiled: March 15, 2010Date of Patent: September 30, 2014Assignee: Nipro CorporationInventors: Akihiko Ishizaki, Katsuhiro Hiejima, Tomohiro Uchimura
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Publication number: 20140288407Abstract: An electrocardiograph measures an electrocardiac signal by processing electric signals detected by bioelectrode pads. The bioelectrode pads each includes a plurality of sheets of electrodes disposed by being stacked on each other; conductive gel sheets disposed alternately with the sheets of electrodes and interposed between the electrodes; and a dynamic pressure stabilizing plate. The electrocardiograph includes a first differential circuit for obtaining an electrocardiac source signal by taking the difference between signals each obtained from any one of the electrodes of each of two bioelectrode pads; a second differential circuit for obtaining a body motion noise signal by taking the difference between signals obtained from any two of the electrodes of each of said two bioelectrode pads; and a body motion noise removing circuit for removing the low frequency components of the body motion noise signal of each of said two bioelectrode pads from the electrocardiac source signal.Type: ApplicationFiled: November 2, 2011Publication date: September 25, 2014Applicants: NIPRO CORPORATION, HARADA ELECTRONICS CO., LTD.Inventors: Yoshihiko Sano, Masahide Harada
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Patent number: 8820119Abstract: To provide a vial with low alkali elution and a method for producing the same by removing a deteriorated region caused by processing on an internal surface of a vial. A vial with reduced alkali elution and a method for producing the same by forming vials from borosilicate glass tubes comprises a first step of forming a borosilicate glass tube into a cup-shaped body by formation of a bottom of a vial, and a second step of forming the cup-shaped body into the vial by formation of a mouth of the cup-shaped body.Type: GrantFiled: May 15, 2006Date of Patent: September 2, 2014Assignee: Nipro CorporationInventors: Hideo Kuwabara, Hideki Yamauchi, Yoshitaka Ishimi, Shinichiro Senga
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Publication number: 20140187744Abstract: The purpose of the present invention is to establish a novel therapy method for hyperbilirubinemia and therefore, to provide a bilirubin excretion enhancer. The present invention provides a bilirubin excretion enhancer comprising, as an active ingredient, a serum albumin domain II-like protein comprising a serum albumin subdomain IIA. In one embodiment, the serum albumin subdomain IIA has an amino acid sequence of SEQ ID NO: 1. In one embodiment, the serum albumin domain II-like protein is a serum albumin domain II. In one embodiment, the serum albumin domain II comprises the amino add sequence of SEQ ID NO: 4.Type: ApplicationFiled: August 9, 2012Publication date: July 3, 2014Applicant: NIPRO CORPORATIONInventors: Masaki Otagiri, Toru Maruyama, Yu Ishima, Ai Minomo
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Patent number: 8764703Abstract: In a pre-filled syringe having an intermediate gasket, a liquid drug is enclosed in the second chamber located on the base end side with respect to the intermediate gasket while a powdered drug is enclosed in the first chamber located on the front end side with respect to the intermediate gasket. The intermediate gasket has at least two layers including a front end layer corresponding to a wall of the first chamber and a base end layer corresponding to a wall of the second chamber, and also has a low water-absorptive layer in the layer on the base end side with respect to the front end layer. The base end layer is formed of a material having low water-absorptivity and not lowering a pH of the liquid drug.Type: GrantFiled: June 8, 2011Date of Patent: July 1, 2014Assignee: Nipro CorporationInventors: Takashi Asai, Tsutomu Takahashi, Kenyu Ito, Atsushi Ishikawa
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Patent number: D707824Type: GrantFiled: August 20, 2012Date of Patent: June 24, 2014Assignee: Nipro CorporationInventor: Koichi Murai
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Patent number: D707825Type: GrantFiled: August 20, 2012Date of Patent: June 24, 2014Assignee: Nipro CorporationInventor: Koichi Murai
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Patent number: D709198Type: GrantFiled: August 20, 2012Date of Patent: July 15, 2014Assignee: Nipro CorporationInventor: Koichi Murai
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Patent number: D713525Type: GrantFiled: November 27, 2013Date of Patent: September 16, 2014Assignee: Nipro CorporationInventors: Takeshi Oguro, Hideki Yagi
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Patent number: D721171Type: GrantFiled: July 2, 2013Date of Patent: January 13, 2015Assignee: Nipro CorporationInventor: Koichi Murai