Patents Assigned to Nipro Corporation
  • Patent number: 7914494
    Abstract: An indwelling catheter comprises a tube, a female connector and an elastically deformable hemostasis valve which can be pressed by a male connector. An opening taper portion tapered forwardly is formed in a longitudinal intermediate portion of an inner circumferential surface of the female connector. The elastically deformable hemostasis valve is provided longitudinally slidably in the opening taper portion of the female connector and an inside portion extending rearwardly from the opening taper portion. The hemostasis valve includes; a body having a hollow form opened at its front and rear ends or a tubular portion fitted over the connecting portion from a rearward direction; and an openable/closable portion being opened by elastic deformation of the body or the tubular portion.
    Type: Grant
    Filed: September 27, 2007
    Date of Patent: March 29, 2011
    Assignee: Nipro Corporation
    Inventor: Katsuhiro Hiejima
  • Patent number: 7910360
    Abstract: An apparatus and method for inoculating a biological substrate with cells include provision for rotating a container in which the substrate and a cell suspension are received about first and second axes of rotation. The apparatus comprises said container, first drive means for rotatably supporting the container about the first axis, and second drive means for rotatably supporting the first drive means about the second axis. The first and second axes of rotation do not lie in the same plane and extend in different directions so that the container revolves around the second axis while the container is rotating about the first axis. The inoculation method utilizes this apparatus.
    Type: Grant
    Filed: August 18, 2004
    Date of Patent: March 22, 2011
    Assignees: JAPAN as represented by PRESIDENT OF NATIONAL CARDIOVASCULAR CENTER, Nipro Corporation
    Inventors: Toshiya Fujisato, Takuro Kogoshi, Yusuke Suga, Akio Kishida, Takeshi Nakatani, Soichiro Kitamura
  • Patent number: 7908935
    Abstract: The inventors perfected the present invention upon finding that a conventional fecal sampling stick is given a hollow structure that has openings a certain distant apart, permitting in aspiration through the capillary tube phenomenon. That is, the present invention is a feces collection container for collecting faeces as an analyte, which comprises a fecal sampling stick which has a holding part (11) at a base, a fecal sampling part (12) at a tip and is formed a hollow passage with openings at the tip and on the base side a predetermined distance from the tip.
    Type: Grant
    Filed: December 15, 2006
    Date of Patent: March 22, 2011
    Assignee: Nipro Corporation
    Inventors: Mitsuru Hasegawa, Yoshikatsu Tomita, Seiji Okamoto
  • Patent number: 7893212
    Abstract: The present invention provides an S-nitroso group-containing albumin, comprising an S-nitroso group introduced to at least one lysine in the amino acid sequence for albumin. The S-nitro group has been introduced into a lysine in the S-nitroso group-containing albumin of the invention to allow more S-nitroso groups to be included in the albumin, thus ensuring more potent inhibition of cancer cells in NO groups.
    Type: Grant
    Filed: August 29, 2008
    Date of Patent: February 22, 2011
    Assignee: Nipro Corporation
    Inventors: Masaki Otagiri, Keisuke Nakajo, Naohisa Katayama, Toshiya Kai
  • Patent number: 7883864
    Abstract: A method of efficiently removing or fixing donor cells from a native tissue of mammalian origin comprises immersing the tissue in a treating solution, and irradiating the tissue with microwave while maintaining the temperature thereof in the range between 0° C. and 40° C.
    Type: Grant
    Filed: December 11, 2003
    Date of Patent: February 8, 2011
    Assignees: Japan as represented by President of National Cardiovascular Center, Nipro Corporation
    Inventors: Toshiya Fujisato, Akio Kishida, Seiichi Funamoto, Takeshi Nakatani, Soichiro Kitamura
  • Patent number: 7846127
    Abstract: A multi lumen catheter including an inner tube having a front tip, an outer tube, a tube or lumen for inserting a guide wire, a blood extraction lumen and a blood return lumen which are formed in the outer tube and inner tube, respectively, or both in the outer tube, wherein the inner tube is inserted in the outer tube, and allowed to slide relative thereto, and the front tip is jointed to the front end of the outer tube to shut off communication of the lumens with the exterior. A multi-lumen catheter with balloon includes a balloon provided on a tabular body at a front end thereof, a blood return port and a blood extraction port provided in the tubular body on opposite sides of the balloon, and an outer cylinder slidable on the tubular body to close the blood extraction and blood return ports and the balloon.
    Type: Grant
    Filed: September 20, 2007
    Date of Patent: December 7, 2010
    Assignee: Nipro Corporation
    Inventors: Junichi Igarashi, Katsuhiro Hiejima
  • Patent number: 7837042
    Abstract: The invention relates to a hollow fiber membrane module comprising polysulfone type selectively permeable hollow fiber membranes which contain a polysulfone-based resin and a hydrophilic polymer as main components, wherein (A) the content of the hydrophilic polymer in the uppermost layer of the inner surface of the hollow fiber membrane is at least 1.1 times larger than the content of the hydrophilic polymer in the proximate layer of the inner surface of the membrane, and (B) the content of the hydrophilic polymer in the uppermost layer of the outer surface of the hollow fiber membrane is at least 1.1 times larger than the content of the hydrophilic polymer in the uppermost layer of the inner surface of the membrane. The hollow fiber membrane module is exposed to a radioactive ray, on condition that the oxygen concentration of an ambient atmosphere around the hollow fiber membrane is from 0.001 to 0.1%, and that the moisture content of the hollow fiber membrane to the weight thereof is from 0.2 to 7 mass %.
    Type: Grant
    Filed: August 9, 2005
    Date of Patent: November 23, 2010
    Assignee: Nipro Corporation
    Inventors: Hideyuki Yokota, Kimihiro Mabuchi, Noriko Monden, Noriaki Kato, Yuuki Hatakeyama, Takashi Sunohara, Toshiaki Masuda
  • Patent number: 7837622
    Abstract: A recording medium includes a sensor circuit unit generating a current in accordance with a blood glucose level in blood, and a control unit calculating blood glucose level data from the data obtained by digital conversion of the generated current at signal processing unit, writing the calculated data to an EEPROM as a memory unit, reading the blood glucose level data from EEPROM and transmitting the same to a portable terminal on which recording medium is mounted, through a communication control unit. The recording medium further includes a power supply control unit receiving power from the portable terminal on which the recording medium is mounted, and supplying power to various portions in the recording medium.
    Type: Grant
    Filed: August 6, 2002
    Date of Patent: November 23, 2010
    Assignee: Nipro Corporation
    Inventors: Takehito Itoh, Hideyuki Tomita
  • Patent number: 7833321
    Abstract: There is provided a protective filter 1 for an extracorporeal circulation circuit pressure monitor, having a dialysis device side housing 2, an extracorporeal circulation circuit side housing 3, and a hydrophobic filter 4 held between both the housings, which allows passage of a gas but does not allow passage of a liquid, characterized in that a plurality of ribs 27 and 38 capable of supporting the hydrophobic filter 4 are respectively provided in both housings, and a protective member 5 for preventing direct contact between the ribs 38 and the hydrophobic filter 4 is interposed between the ribs 38 provided in the extracorporeal circulation circuit side housing 3 and the hydrophobic filter 4.
    Type: Grant
    Filed: August 31, 2007
    Date of Patent: November 16, 2010
    Assignee: Nipro Corporation
    Inventors: Katsunori Kawai, Akinobu Yamaguchi
  • Publication number: 20100286565
    Abstract: To provide a means capable easily releasing twist of two or more guidewires passed through a guiding catheter without pulling out the guidewires. A twist releasing apparatus has a shaft, a first tube formed at the tip of the shaft and has a first lumen through which two or more guidewires can be passed, a second tube disposed through a gap at the tip side in the axis direction relative to the first tube and has a second lumen through the two or more guidewires can be passed, and a connection portion for connecting the first tube and the second tube so that the two or more guidewires can be passed through the first lumen and the second lumen. The second tube has a slit that is formed in an axis direction and can be elastically deformed. The connection portion can be elastically deformed into a curved shape in the axis direction.
    Type: Application
    Filed: March 22, 2010
    Publication date: November 11, 2010
    Applicant: Nipro Corporation
    Inventors: Shinsuke Nanto, Satoru Mori
  • Publication number: 20100249718
    Abstract: A liquid medicine self-administration device including a flexible reservoir, an operating member, a pushing member to move with respect to the operating member and to induce pressure deformation of the reservoir, and engaging means engages the operating member. With the operating member engaged by the engaging means, the pushing member is relatively moved to the operating member based on restoring force of a spring member to push the reservoir by the pushing member. By disengaging means moving in unison with the pushing member, the engaging means is released from an engaged state with respect to the operating member, when the pushing member has moved to a predetermined location while pushing the reservoir.
    Type: Application
    Filed: March 15, 2010
    Publication date: September 30, 2010
    Applicant: NIPRO CORPORATION
    Inventors: Akihiko Ishizaki, Katsuhiro Hiejima, Tomohiro Uchimura
  • Publication number: 20100249819
    Abstract: A disposable lancing device including: a housing; a spring member; a lancet having a skin puncture needle, the spring member and the lancet being housed within the housing such that a needle tip of the skin puncture needle is adapted to be projected out from the housing under urging of the lancet by the spring member to perform skin puncture procedure; and a protective cap having a needle passage hole and covering the needle tip of the skin puncture needle, the protective cap being adapted to separate from the skin puncture needle and rotate so that the needle passage hole of the protective cap is positioned on a path of projection of the skin puncture needle, and the skin puncture procedure is performed with the protective cap supported on the housing.
    Type: Application
    Filed: March 15, 2010
    Publication date: September 30, 2010
    Applicant: NIPRO CORPORATION
    Inventors: Kohzo Ishikura, Ken Suzuki, Takeshi Yamaguchi
  • Publication number: 20100219094
    Abstract: A drug container with no need to peel a gas-barrier film or with no need to contain a desiccant, an oxygen absorbent or the like, in which the contents therein can be seen by the naked eyes. The container (10) comprises a front sheet (20) and a rear sheet (22), the front sheet (20) and the rear sheet (22) being fusion-bonded each other so as to form a space (14) therebetween, wherein the front sheet is constituted of a multilayered film having a linear-polyolefin layer as the outermost layer, wherein the rear sheet is constituted of a multilayered film having at least one selected from a group consisting of a metal foil, a vapor-deposited metal layer and a vapor-deposited inorganic layer, and wherein a transparent covering sheet (24) comprising a film having a vapor-deposited metal oxide layer is fusion-bonded to the front sheet so that the entire outer surface of at least a part of the front sheet which forms the space can be covered with the transparent covering sheet (24).
    Type: Application
    Filed: May 22, 2007
    Publication date: September 2, 2010
    Applicant: Nipro Corporation
    Inventors: Masashi Moteki, Minoru Honda, Kenji Omori
  • Publication number: 20100206748
    Abstract: Provided is a stress measurement kit that is economical and that has good sensitivity. The stress measurement kit for measuring a stress level of a test subject includes: (A) a sensor chip including an electrically insulating substrate, and an electrode system that is placed on the electrically insulating substrate and that includes at least a working electrode and a counter electrode, wherein glucose dehydrogenase (GDH) and an electron mediator are immobilized on the working electrode; (B) a polysaccharide; and (C) a sensor body including an insertion hole into which the sensor chip is inserted, an electrical measurement means that is electrically connected to the electrode system of the sensor chip in a state where the sensor chip is inserted into the insertion hole, and a conversion means by which a current value or an electric quantity measured by the electrical measurement means is converted into an amylase activity value.
    Type: Application
    Filed: July 31, 2008
    Publication date: August 19, 2010
    Applicant: NIPRO CORPORATION
    Inventors: Mitsuhiro Morita, Toshiaki Baba, Hiroshi Yoshida, Emi Nishimura
  • Patent number: 7753893
    Abstract: A drug solution injector for determining an accurate injection volume of a drug solution by weighing the drug solution reservoir with a weighing scale. A drug solution injector is provided with a weighing scale that is compact, does not disturb handling and enables an accurate determination of the injection volume of the drug solution. A drug solution injector includes a drug solution reservoir composed of a chamber for reserving a drug solution therein and pressurization mechanism for pushing out of the reserved drug solution. An injection line is connected to the reservoir to inject the drug solution to the body. The drug solution reservoir is fixedly provided with a weighing scale for measuring a weight of the drug solution stored in the drug solution reservoir.
    Type: Grant
    Filed: February 8, 2005
    Date of Patent: July 13, 2010
    Assignee: Nipro Corporation
    Inventors: Yasuhiko Morita, Atsushi Funayama, Satoki Hino
  • Patent number: 7754879
    Abstract: A porphyrin compound represented by general formula (A): Also disclosed are a porphyrin metal complex-albumin inclusion compound having a porphyrin compound, in which M denotes Fe or Co, included in albumin, and an artificial oxygen carrier containing the porphyrin metal complex-albumin inclusion compound as an active component.
    Type: Grant
    Filed: March 13, 2009
    Date of Patent: July 13, 2010
    Assignee: Nipro Corporation
    Inventors: Eishun Tsuchida, Teruyuki Komatsu, Akito Nakagawa, Naomi Ohmichi
  • Patent number: 7740613
    Abstract: An inserter includes a housing, a plunger holding an indwelling member, a lifter contained in the housing in the state where the lifter is axially movable relative to the plunger, a needle holder contained in the housing and having a projection that can be latched by the plunger and the lifter, an insertion needle held by the needle holder and inserted in a cannula, and a spring provided between the plunger and the lifter and applying a biasing force in the direction of biasing the plunger and the lifter away from each other. The projection of the needle holder is latched by the plunger before the indwelling member reaches the body surface of the user, and latched by the lifter after the indwelling member reaches the body surface of the user.
    Type: Grant
    Filed: December 12, 2008
    Date of Patent: June 22, 2010
    Assignee: Nipro Corporation
    Inventors: Hiroyuki Yokoi, Yukinori Ebara
  • Patent number: D622378
    Type: Grant
    Filed: April 2, 2009
    Date of Patent: August 24, 2010
    Assignee: Nipro Corporation
    Inventor: Osamu Katoh
  • Patent number: D627459
    Type: Grant
    Filed: September 9, 2009
    Date of Patent: November 16, 2010
    Assignee: Nipro Corporation
    Inventors: Yoshikuni Uchida, Youta Sekiduka, Hirokazu Sutou
  • Patent number: D634425
    Type: Grant
    Filed: September 24, 2009
    Date of Patent: March 15, 2011
    Assignee: Nipro Corporation
    Inventors: Kazuhiro Watanabe, Naoki Nakagawa, Yuki Hiraoka